BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0228.p (575 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2816 [J] COG0442 Prolyl-tRNA synthetase Rso Ralstonia solanac... 926 0.0 PA0956 [J] COG0442 Prolyl-tRNA synthetase Pae Pseudomonas aerugi... 722 0.0 NMB1339 [J] COG0442 Prolyl-tRNA synthetase Nme Neisseria meningi... 702 0.0 NMA1553 [J] COG0442 Prolyl-tRNA synthetase NmA Neisseria meningi... 699 0.0 STM0242 [J] COG0442 Prolyl-tRNA synthetase Sty Salmonella typhim... 669 0.0 >RSc2816 [J] COG0442 Prolyl-tRNA synthetase Rso Ralstonia solanacearum Length = 574 Score = 926 bits (2392), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/554 (79%), Positives = 493/554 (88%), Gaps = 1/554 (0%) Query: 1 MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGAGIYTYMPMGLRVIRKVEAIVREE 60 M+AS+FFISTLKEAP+DAEIVSHKLMMRAGMIK+LGAG+YTYMP+GLRVIRKVE IVREE Sbjct: 1 MKASQFFISTLKEAPADAEIVSHKLMMRAGMIKKLGAGLYTYMPVGLRVIRKVEQIVREE 60 Query: 61 MNRAGAVELLMPVVQPAELWQETGRWNKMGAELMRVKDRHGRDFAIQPTSEEVVTDVART 120 MN +GAVE+LMPVVQPAELWQETGRW+KMG E+MRVKDRH RD IQPTSEEVVTD+ART Sbjct: 61 MNASGAVEVLMPVVQPAELWQETGRWDKMGDEMMRVKDRHERDLVIQPTSEEVVTDIART 120 Query: 121 ELRSYKQLPVNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVDGLKKSYQAMYDA 180 E+RSYKQ+PVNFY IQTKFRDERRPRFG+MRGREFTMKDAYSFDRD +GLK SY+ MY A Sbjct: 121 EIRSYKQMPVNFYQIQTKFRDERRPRFGIMRGREFTMKDAYSFDRDAEGLKVSYEKMYGA 180 Query: 181 YVRIFTRFGLEFRAVAADNGAIGGSGSHEFHVIAATGEDALVYCPTSDYAANMEAAEALP 240 Y RIF RFGLEFRAVAADNGAIGGSGSHEFHVIA TGEDA+VY P SDYAAN+EAAEAL Sbjct: 181 YTRIFQRFGLEFRAVAADNGAIGGSGSHEFHVIADTGEDAIVYSPDSDYAANIEAAEALA 240 Query: 241 VDSSRGAATQALEKTATPGKSKCEAVAELLGLPLARTVKSIVLAVDNEDPAKKEIWLLLL 300 RGAAT+AL KT TP ++KCEAVAE LG+ L RTVKSIVLA D E + +IWLLLL Sbjct: 241 PAMPRGAATEALTKTHTPKRAKCEAVAEQLGIALQRTVKSIVLAKDVEG-GEPQIWLLLL 299 Query: 301 RGDHELNEVKASKIPGLSTYRFANEAEIVEWFGTPPGYLGPIGTKKPVKVVADRTVANMA 360 RGDHELNE+KASK+PGL+ +RFA E EI+ FGTPPGYLGPIGTK+PVKVVADRTVA M+ Sbjct: 300 RGDHELNEIKASKVPGLADFRFATEGEILRAFGTPPGYLGPIGTKQPVKVVADRTVAAMS 359 Query: 361 DFVCGANEADFHYTGANWGRDLPEPLVADIRNVVEGDASPDGRGVLAIQRGIEVGHVFQL 420 DFV GANE DFHYTG NWGRDLPE V D+RNVVEGD SPDG+G LAI RGIEVGHVF L Sbjct: 360 DFVVGANEEDFHYTGVNWGRDLPEAEVYDLRNVVEGDPSPDGKGTLAICRGIEVGHVFML 419 Query: 421 GTTYSEAMKATYLDESGKPQPLVMGCYGIGVTRILGAAIEQNFDDRGIIWPTSIAPFEVV 480 GT YSE+M AT+LDE+GK QP++MGCYGIG+TRILGAAIEQN+D RGIIWP SIAPFEVV Sbjct: 420 GTRYSESMSATFLDENGKTQPMMMGCYGIGITRILGAAIEQNYDARGIIWPVSIAPFEVV 479 Query: 481 LCPMGYDRSEAVKTEIDKLYAQLTEAGVDVVLDDRGERPGAMFADWELIGVPHRIVVGDR 540 +CP+GYDRSEAV+ E D+L+A+L AG+DV+LDDRGERPGAMFADWELIGVP R+VVG+R Sbjct: 480 ICPVGYDRSEAVRAEADRLHAELAAAGIDVILDDRGERPGAMFADWELIGVPFRVVVGER 539 Query: 541 GLKDGNIEYQGRRD 554 GLKDG +E QGRRD Sbjct: 540 GLKDGKLELQGRRD 553 >PA0956 [J] COG0442 Prolyl-tRNA synthetase Pae Pseudomonas aeruginosa Length = 571 Score = 722 bits (1863), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/577 (59%), Positives = 443/577 (76%), Gaps = 10/577 (1%) Query: 1 MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGAGIYTYMPMGLRVIRKVEAIVREE 60 MR S++ +STLKE P+DA ++SH+L++RAGMI+RL +G+YT++PMGLRV+RKVE IVREE Sbjct: 1 MRTSQYLLSTLKETPADAVVISHQLLLRAGMIRRLASGLYTWLPMGLRVLRKVETIVREE 60 Query: 61 MNRAGAVELLMPVVQPAELWQETGRWNKMGAELMRVKDRHGRDFAIQPTSEEVVTDVART 120 MN AGA+E+LMP VQPAELWQE+GRW + G EL+R+KDRH R+F + PT EEV+TD+AR Sbjct: 61 MNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKDRHEREFCVGPTHEEVITDLARN 120 Query: 121 ELRSYKQLPVNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVDGLKKSYQAMYDA 180 EL SYKQLP+NFY IQTKFRDE RPRFGLMRGREF MKDAYSF D L+++Y MY A Sbjct: 121 ELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQA 180 Query: 181 YVRIFTRFGLEFRAVAADNGAIGGSGSHEFHVIAATGEDALVYCPTSDYAANMEAAEALP 240 Y +IF+R GL+FR V ADNG+IGGSGSHEFHV+A +GED +V+ +SDYAAN+E AEA+P Sbjct: 181 YSKIFSRLGLDFRPVQADNGSIGGSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVP 240 Query: 241 VDSSRGAATQALEKTATPGKSKCEAVAELLGLPLARTVKSIVLAVDNEDPAKKEIWLLLL 300 +S+RG+AT+ + TP A+ + LP+ +T+K++V+ E + L++ Sbjct: 241 RESARGSATEDMRLVDTPNTKTIAALVDGFQLPIEKTIKTLVVHGAEEG----TLVALIV 296 Query: 301 RGDHELNEVKASKIPGL-STYRFANEAEIVEWFGTPPGYLGPIGTKKPVKVVADRTVANM 359 RGDHELNE+KA+ P + S FA+EAEI G PG LGP+ P+ + DR+VA M Sbjct: 297 RGDHELNEIKAANQPLVASPLVFASEAEIRAAIGAGPGSLGPVNL--PIACIVDRSVALM 354 Query: 360 ADFVCGANEADFHYTGANWGRDLPEPLVADIRNVVEGDASPDGRGVLAIQRGIEVGHVFQ 419 +DF GAN D HY G NW RDLP P VAD+RNVVEGD SPDG+G L I+RGIEVGH+FQ Sbjct: 355 SDFAAGANIEDKHYFGVNWERDLPLPEVADLRNVVEGDPSPDGKGTLVIKRGIEVGHIFQ 414 Query: 420 LGTTYSEAMKATYLDESGKPQPLVMGCYGIGVTRILGAAIEQNFDDRGIIWPTSIAPFEV 479 LGT YSEAMK + L E GKP L+MGCYGIGV+R++ AAIEQN D+RGI+WP+++APF++ Sbjct: 415 LGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGVSRVVAAAIEQNHDERGILWPSALAPFQI 474 Query: 480 VLCPMGYDRSEAVKTEIDKLYAQLTEAGVDVVLDDRGER--PGAMFADWELIGVPHRIVV 537 L P+ Y+ +E+VK DKLYA+LT AG +V+LDDR ++ PG FAD ELIG+PHRIV+ Sbjct: 475 ALVPLKYE-TESVKQATDKLYAELTAAGFEVLLDDRDKKTSPGVKFADMELIGIPHRIVI 533 Query: 538 GDRGLKDGNIEYQGRRDAEATQVPLAEALAFIQGKLA 574 DRGL +G +EY+GRRD+E+ +P+ E ++FI KL+ Sbjct: 534 SDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLS 570 >NMB1339 [J] COG0442 Prolyl-tRNA synthetase Nme Neisseria meningitidis MC58 Length = 570 Score = 702 bits (1812), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/576 (59%), Positives = 423/576 (73%), Gaps = 7/576 (1%) Query: 1 MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGAGIYTYMPMGLRVIRKVEAIVREE 60 M+AS+FFISTLKEAP++A + SHKLM+RAG+IK +G+YT+MPMGLRV+RKVE +VREE Sbjct: 1 MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMPMGLRVLRKVENVVREE 60 Query: 61 MNRAGAVELLMPVVQPAELWQETGRWNKMGAELMRVKDRHGRDFAIQPTSEEVVTDVART 120 M RAG+VELLMPVVQPAELWQE+GRW G EL+R+KDRH RDF + PT EEV+ D+ R Sbjct: 61 MARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDRDFCMGPTCEEVIADIVRK 120 Query: 121 ELRSYKQLPVNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVDGLKKSYQAMYDA 180 E+ SYKQLP NFYHIQTKFRDE RPRFG+MR REF MKDAYSF D L+ +YQ MYDA Sbjct: 121 EINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDAYSFHADYASLQTTYQDMYDA 180 Query: 181 YVRIFTRFGLEFRAVAADNGAIGGSGSHEFHVIAATGEDALVYCPTSDYAANMEAAEALP 240 Y RIFTR GL FR VAAD G+IGG+GSHEF V+A +GED + Y TSDYAAN+E A LP Sbjct: 181 YCRIFTRLGLAFRPVAADTGSIGGTGSHEFQVLAESGEDVIAYSDTSDYAANIELAPTLP 240 Query: 241 VDSSRGAATQALEKTATPGKSKCEAVAELLGLPLARTVKSIVLAVDNEDPAKKEIWLLLL 300 + R AA L K TP +++ + L +P+ +T+KSIV+ +NE E+ LLLL Sbjct: 241 LKGERAAAQAELVKVHTPNVKTIDSLVDFLSIPIEKTLKSIVVEGENE----GELILLLL 296 Query: 301 RGDHELNEVKASKIPGL-STYRFANEAEIVEWFGTPPGYLGPIGTKKPVKVVADRTVANM 359 RGDHE N++KA K+ G+ S A+ A IVE FG G LGP+G KV AD Sbjct: 297 RGDHEFNDIKAEKLAGVKSPLTMASPAAIVEQFGANGGSLGPVGFAG--KVYADFATEKG 354 Query: 360 ADFVCGANEADFHYTGANWGRDLPEPLVADIRNVVEGDASPDGRGVLAIQRGIEVGHVFQ 419 AD+V GANE D+HYTG N+GRD EP D+RNVVEGD SPDG+G L + RGIEVGHVFQ Sbjct: 355 ADWVIGANEDDYHYTGFNFGRDAAEPEFVDLRNVVEGDESPDGQGRLKLARGIEVGHVFQ 414 Query: 420 LGTTYSEAMKATYLDESGKPQPLVMGCYGIGVTRILGAAIEQNFDDRGIIWPTSIAPFEV 479 L Y++AM ++LD +GK Q + MGCYGIG+TR++ AAIEQN D++GIIW ++APFEV Sbjct: 415 LRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAIEQNNDEKGIIWTKAMAPFEV 474 Query: 480 VLCPMGYDRSEAVKTEIDKLYAQLTEAGVDVVLDDRGERPGAMFADWELIGVPHRIVVGD 539 V+ PM Y +S+ V+ DK+YA+L AG DV+LDDR ER G + D EL+G+PHRIV+GD Sbjct: 475 VIVPMNYKKSDTVREAADKIYAELLAAGADVLLDDRDERAGVLLNDSELLGIPHRIVIGD 534 Query: 540 RGLKDGNIEYQGRRDAEATQVPLAEALAFIQGKLAA 575 R LK+GN+EY RRD EA V + E +A + L A Sbjct: 535 RALKEGNVEYAERRDNEAQAVAIGEIVARVTASLNA 570 >NMA1553 [J] COG0442 Prolyl-tRNA synthetase NmA Neisseria meningitidis Z2491 Length = 570 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/576 (59%), Positives = 422/576 (73%), Gaps = 7/576 (1%) Query: 1 MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGAGIYTYMPMGLRVIRKVEAIVREE 60 M+AS+FFISTLKEAP++A + SHKLM+RAG+IK +G+YT+MPMGLRV+RKVE +VREE Sbjct: 1 MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMPMGLRVLRKVENVVREE 60 Query: 61 MNRAGAVELLMPVVQPAELWQETGRWNKMGAELMRVKDRHGRDFAIQPTSEEVVTDVART 120 M RAG+VELLMPVVQPAELWQE+GRW G EL+R+KDRH RDF + PT EEV+ D+ R Sbjct: 61 MARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDRDFCMGPTCEEVIADIVRK 120 Query: 121 ELRSYKQLPVNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVDGLKKSYQAMYDA 180 E+ SYKQLP NFYHIQTKFRDE RPRFG+MR REF MKDAYSF D L+ +Y AMYDA Sbjct: 121 EINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDAYSFHADYASLQTTYDAMYDA 180 Query: 181 YVRIFTRFGLEFRAVAADNGAIGGSGSHEFHVIAATGEDALVYCPTSDYAANMEAAEALP 240 Y RIFTR GLEFR VAAD G+IGG+GSHEF V+A +GED + Y TSDYAAN+E A LP Sbjct: 181 YCRIFTRLGLEFRPVAADTGSIGGTGSHEFQVLAESGEDVIAYSDTSDYAANVELAPTLP 240 Query: 241 VDSSRGAATQALEKTATPGKSKCEAVAELLGLPLARTVKSIVLAVDNEDPAKKEIWLLLL 300 + R AA L K TP E++ E L +P+ +T+KSIV+ +NE EI LLLL Sbjct: 241 LKGERTAAQAELVKVHTPNVKTIESLVEFLNIPVEQTLKSIVVEGENEG----EIVLLLL 296 Query: 301 RGDHELNEVKASKIPGL-STYRFANEAEIVEWFGTPPGYLGPIGTKKPVKVVADRTVANM 359 RGDHE N++KA K+ G+ S A+ A IVE FG G LGP+G KV AD Sbjct: 297 RGDHEFNDIKAEKLAGVKSPLTMASPAAIVEQFGANGGSLGPVGFAG--KVYADFATEKG 354 Query: 360 ADFVCGANEADFHYTGANWGRDLPEPLVADIRNVVEGDASPDGRGVLAIQRGIEVGHVFQ 419 AD+V GANE +HYTG N+GRD EP D+RNVVEGD SPDG+G L + RGIEVGHVFQ Sbjct: 355 ADWVIGANEDGYHYTGFNFGRDAAEPEFVDLRNVVEGDESPDGQGRLKLARGIEVGHVFQ 414 Query: 420 LGTTYSEAMKATYLDESGKPQPLVMGCYGIGVTRILGAAIEQNFDDRGIIWPTSIAPFEV 479 L Y++AM ++LD +GK Q + MGCYGIG+TR++ AAIEQN D++GIIW ++A FEV Sbjct: 415 LRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAIEQNNDEKGIIWTKAMASFEV 474 Query: 480 VLCPMGYDRSEAVKTEIDKLYAQLTEAGVDVVLDDRGERPGAMFADWELIGVPHRIVVGD 539 V+ PM Y +S+ V+ DK+YA+L AG DV+LDDR ER G + D EL+G+PHRIV+GD Sbjct: 475 VIVPMNYKKSDTVREAADKIYAELLAAGADVLLDDRDERAGVLLNDSELLGIPHRIVIGD 534 Query: 540 RGLKDGNIEYQGRRDAEATQVPLAEALAFIQGKLAA 575 R LK+GN+EY RRD EA + + E +A + L A Sbjct: 535 RALKEGNVEYAERRDNEAQAIAIGEIVARVTASLNA 570 >STM0242 [J] COG0442 Prolyl-tRNA synthetase Sty Salmonella typhimurium LT2 Length = 572 Score = 669 bits (1727), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/570 (55%), Positives = 415/570 (72%), Gaps = 5/570 (0%) Query: 1 MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGAGIYTYMPMGLRVIRKVEAIVREE 60 MR S++ +STLKE P+DAE++SH+LM+RAGMI++L +G+YT++P GLRV++KVE IVREE Sbjct: 1 MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREE 60 Query: 61 MNRAGAVELLMPVVQPAELWQETGRWNKMGAELMRVKDRHGRDFAIQPTSEEVVTDVART 120 MN AGA+E+ MPVVQPA+LWQE+GRW + G EL+R DR R F + PT EEV+TD+ R Sbjct: 61 MNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRN 120 Query: 121 ELRSYKQLPVNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDVDGLKKSYQAMYDA 180 EL SYKQLP+NF+ IQTKFRDE RPRFG+MR REF MKDAYSF + L+++Y AMY A Sbjct: 121 ELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAA 180 Query: 181 YVRIFTRFGLEFRAVAADNGAIGGSGSHEFHVIAATGEDALVYCPTSDYAANMEAAEALP 240 Y RIF+R GL+FRAV AD G+IGG+ SHEF V+A +GED +V+ SDYAAN+E AEA+ Sbjct: 181 YSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIA 240 Query: 241 VDSSRGAATQALEKTATPGKSKCEAVAELLGLPLARTVKSIVLAVDNEDPAKKEIWLLLL 300 + R AATQ + TP + E LP+ +TVK++++ + +K + LL+ Sbjct: 241 PQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVKD--SKSPLVALLV 298 Query: 301 RGDHELNEVKASKIPGL-STYRFANEAEIVEWFGTPPGYLGPIGTKKPVKVVADRTVANM 359 RGDHELNEVKA K+P + S FA E EI PG LGP+ P+ V+ DRTVA M Sbjct: 299 RGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAGPGSLGPVNM--PIPVIIDRTVAAM 356 Query: 360 ADFVCGANEADFHYTGANWGRDLPEPLVADIRNVVEGDASPDGRGVLAIQRGIEVGHVFQ 419 +DF GAN HY G NW RD+ P+VADIRNVV GD SPDG+G L I+RGIEVGH+FQ Sbjct: 357 SDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQ 416 Query: 420 LGTTYSEAMKATYLDESGKPQPLVMGCYGIGVTRILGAAIEQNFDDRGIIWPTSIAPFEV 479 LGT YSEA+KA+ E G+ Q L MGCYGIGVTR++ AAIEQNFD+RGI+WP +IAPF+V Sbjct: 417 LGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQV 476 Query: 480 VLCPMGYDRSEAVKTEIDKLYAQLTEAGVDVVLDDRGERPGAMFADWELIGVPHRIVVGD 539 + PM +S V+ +KLY++L G++V++DDR ERPG MFAD ELIG+PH IV+GD Sbjct: 477 AILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGD 536 Query: 540 RGLKDGNIEYQGRRDAEATQVPLAEALAFI 569 R L + +IEY+ RR E + + + + ++ Sbjct: 537 RNLDNDDIEYKYRRSGEKSLIKTGDIVDYL 566