BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0022.0117.p         (383 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH1161 [GEPR] COG0477 Permeases of the major facilitator superfa...    66   2e-10
BH0472 [GEPR] COG0477 Permeases of the major facilitator superfa...    65   3e-10

>BH1161 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha
           Bacillus halodurans
          Length = 406

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 95/381 (24%), Positives = 165/381 (43%), Gaps = 33/381 (8%)

Query: 14  RHAAMSLSAALPCDIVLYLLLPMYAAQFHVS-LAEAGVLLAANRLVRIAGYRWVASFYAQ 72
           R  A+  + AL  D ++ ++LP+Y  +F ++ + + GVLL+ NRL+R+     V  FY  
Sbjct: 8   RWIAILTAIALLGDSMILIVLPLYWEEFGLTAIWQVGVLLSVNRLIRLPINPLVGWFYRT 67

Query: 73  RGDRPTCTLAVCAAILCALGYTVASGFWALLPLRLLWGMAFAGLNLS--TQAMSTANPQG 130
              R    +A+  A++  L Y    GF  LL  R+LWG+A+A + L      +  +N + 
Sbjct: 68  YERRTGFFIAMSLALVTTLAYGYVQGFIWLLIARILWGVAWAFIRLGGYLTVLDHSNSRN 127

Query: 131 AARRSGRSRGVIAIGPMLWLPTAALLAPHIGPRMVFALVAATALLGL-LAARRLPQHAYA 189
                G   G+  +G ++ +    ++        V  L A  A   L    + +P+   +
Sbjct: 128 RGELIGLYNGLWGLGGLVGMLAGGIVVEQTSIAFVTTLFAGAACFSLPTLFKVIPR---S 184

Query: 190 PPQPRRWKLPNALDWW----------SFLEGLTLDGLFIVGLAYMSKQSFGAD------- 232
             +  R K     DW+          SF  GL + G+F   L+   ++    +       
Sbjct: 185 VSEQVRDKTDGKGDWFSIHTGSILLLSFTTGLVIFGVFATTLSPFVERMIDDNWTWHGLV 244

Query: 233 --GELVAGVLMALRYAGEIVLSPLGGWLAERFGAVKVLVTLSLATCVALVGFGGGLLWLF 290
                VAG++ A+R+A +  ++P+ G   +R    K  V  S+   +A + F  G +  F
Sbjct: 245 IGAATVAGLIQAVRWAWDPFVAPMVGKRLDRMRT-KGPVVFSMLLMIASLFFIAGSVHDF 303

Query: 291 AGLIVILRALQL------PLLAPIVAARTPAAQRVHALAGRAIWRDIGAGMGPMLAGLLL 344
               V L   QL       L   + A       RV  +    I  D+GA +GP++  L++
Sbjct: 304 VLASVFLLVFQLISTIFVTLTDSLAAEVANQTDRVRMMTAHTIAIDLGAALGPLIGFLVV 363

Query: 345 PVMSSLWLYSLAASALALAAI 365
             +   +LY + +S L L AI
Sbjct: 364 ATVHLSFLYFMTSSWLLLLAI 384


>BH0472 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha
           Bacillus halodurans
          Length = 417

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 99/395 (25%), Positives = 174/395 (44%), Gaps = 36/395 (9%)

Query: 1   MTTPDHRQADIDSRHAAMSLSAALPCDIVLYLLLPMYAAQFHV-SLAEAGVLLAANRLVR 59
           MT  +H       +  A+  +  L  D +LY+ LP+Y  +  + SL E G++L+ NR VR
Sbjct: 1   MTKSEHAPESKSVKVVALVTALCLLGDSLLYVALPIYYREVGLQSLWEVGIILSLNRFVR 60

Query: 60  IAGYRWVASFYAQRGDRPTCTLAVCAAILCALGYTVASGFWALLPLRLLWGMAFAGLNLS 119
           I     V   Y     R    +AV   ++  +GY V  GF+  + LRLLWG+A++ L L 
Sbjct: 61  IPINPLVGKCYQHVTLRTGLLIAVSLTLVTTIGYGVGYGFFVWVILRLLWGIAWSFLRLG 120

Query: 120 --TQAMSTANPQGAARRSGRSRGVIAIGPMLWLPTAALLAPHIG---PRMVFALVAATAL 174
                +  A      +  G+  G+  +G +  +    +LA  IG     ++F ++A  A+
Sbjct: 121 GLFTVLEEATDSNRGKLMGQYNGLYRLGSLGGMLGGGILASFIGLSATAIIFGVLAVLAI 180

Query: 175 ------LGLLAARRLPQHAYAPPQPRRWKL--PNALDWWSFLEGLTLDGLFIVG--LAYM 224
                 +  LA  R  Q      + +R  L   +A+   S    L L    + G  L+ +
Sbjct: 181 PYVLRYVPSLAQERTGQPEGDSTEKKRKGLYGRHAILAISSGLLLALFLQGLFGSTLSLL 240

Query: 225 SKQSFGADGELV---------AGVLMALRYAGEIVLSPL-GGWLAERFGAVKVLVTLSLA 274
             + +G    +V         +GVL  +R+  E  L+ L G W     G + + +   + 
Sbjct: 241 MLEHYGETIYIVGMIVGVTALSGVLQGVRWVWEPFLAVLFGHWSDGDRGRLPLFILFLIM 300

Query: 275 TCVALVGFGGGLL------WLFAGLIVILRALQLPLLAPIVAARTPAAQRVH-ALAGRAI 327
           T    +G+G  +L      WL A ++V++ +  L  L   + +     Q  +  +    +
Sbjct: 301 TA---LGYGAMVLSLPLIIWLAAVIVVMVASTALTTLIDALTSDVAKGQDANRVMTSYTV 357

Query: 328 WRDIGAGMGPMLAGLLLPVMSSLWLYSLAASALAL 362
           + D+GA +GP+LA  LL +  SL    L+++ + L
Sbjct: 358 FLDVGAALGPLLAYFLLDIGLSLTFVYLSSAVIFL 392