BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0022.0084.p         (214 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

STM4428 [GEPR] COG0477 Permeases of the major facilitator superf...   119   6e-27
STM2372 [GEPR] COG0477 Permeases of the major facilitator superf...   117   3e-26
yfcJ [GEPR] COG0477 Permeases of the major facilitator superfami...   115   8e-26
ECs3206 [GEPR] COG0477 Permeases of the major facilitator superf...   114   1e-25
PA1993 [GEPR] COG0477 Permeases of the major facilitator superfa...   112   4e-25

>STM4428 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty
           Salmonella typhimurium LT2
          Length = 388

 Score =  119 bits (297), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 70/166 (42%), Positives = 107/166 (64%), Gaps = 1/166 (0%)

Query: 20  TGTSVLQALSPLTLAVFIAFLTIGLQLPVLPLHLKEALGMNATVVGVVVGAQFAAALLSR 79
           T  S    L  ++ A+F+ +LTIG+ L +LPL++++ L ++  ++G+ VG+QF A LL+R
Sbjct: 5   TQHSTSITLFRISAAMFLNYLTIGIPLVMLPLYVQQQLHLSDLLIGIAVGSQFIATLLTR 64

Query: 80  AWAGNVADLRGPKRAVVGGFVAAALSGLIYLASLLWLDQPAISVAVLLAGRVLLALGESL 139
             AG  AD  G +R V+ G    A SGL+ L SL+    P ++ A+L+ GRVLL +GES 
Sbjct: 65  GAAGRKADTSGGRRTVITGQFYCAASGLLMLVSLIAHPVPLLAWAILIVGRVLLGIGESF 124

Query: 140 VITGTMGWGIALVGPQHGGKVMAWLGIAIYAAMA-GLLLGLSINAE 184
           ++TG + WG+ L G  H G+V++W G+A Y A+A G  LGLS+ A 
Sbjct: 125 ILTGNLTWGMWLAGSTHAGQVISWNGMATYGALAIGAPLGLSLYAR 170


>STM2372 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty
           Salmonella typhimurium LT2
          Length = 392

 Score =  117 bits (292), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 70/159 (44%), Positives = 105/159 (66%), Gaps = 1/159 (0%)

Query: 27  ALSPLTLAVFIAFLTIGLQLPVLPLHLKEALGMNATVVGVVVGAQFAAALLSRAWAGNVA 86
           +L  +  AVF+ ++T+GL LPV+PL +   LG + T+VG+ VG QF A +L+R +AG +A
Sbjct: 16  SLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYSNTMVGIAVGIQFFATVLTRGYAGRLA 75

Query: 87  DLRGPKRAVVGGFVAAALSGLIYLASLLWLDQPAISVAVLLAGRVLLALGESLVITGTMG 146
           D  G KR+ + G +A  L+G  +L + L      +  A+L+ GR++L  GES ++TGT+ 
Sbjct: 76  DQYGAKRSALQGMLACGLAGAAWLLAALLPVSAPVKFALLIVGRLILGFGESQLLTGTLT 135

Query: 147 WGIALVGPQHGGKVMAWLGIAIYAAM-AGLLLGLSINAE 184
           WG+ LVGP   GKVM+W G+AIY A+ AG  LGL I++ 
Sbjct: 136 WGLGLVGPTRSGKVMSWNGMAIYGALAAGAPLGLLIHSH 174


>yfcJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco
           Escherichia coli K12
          Length = 392

 Score =  115 bits (288), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 70/166 (42%), Positives = 106/166 (63%), Gaps = 1/166 (0%)

Query: 20  TGTSVLQALSPLTLAVFIAFLTIGLQLPVLPLHLKEALGMNATVVGVVVGAQFAAALLSR 79
           T +S   +L  +  AVF+ ++T+GL LPV+PL +   LG   T+VG+ VG QF A +L+R
Sbjct: 9   TRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYGNTMVGIAVGIQFLATVLTR 68

Query: 80  AWAGNVADLRGPKRAVVGGFVAAALSGLIYLASLLWLDQPAISVAVLLAGRVLLALGESL 139
            +AG +AD  G KR+ + G +A  L+G   L + +         A+L+ GR++L  GES 
Sbjct: 69  GYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVVGRLILGFGESQ 128

Query: 140 VITGTMGWGIALVGPQHGGKVMAWLGIAIYAAMA-GLLLGLSINAE 184
           ++TG + WG+ +VGP+H GKVM+W G+AIY A+A G  LGL I++ 
Sbjct: 129 LLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSH 174


>ECs3206 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs
           Escherichia coli O157:H7
          Length = 392

 Score =  114 bits (286), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 70/166 (42%), Positives = 106/166 (63%), Gaps = 1/166 (0%)

Query: 20  TGTSVLQALSPLTLAVFIAFLTIGLQLPVLPLHLKEALGMNATVVGVVVGAQFAAALLSR 79
           T +S   +L  +  AVF+ ++T+GL LPV+PL +   LG   T+VG+ VG QF A +L+R
Sbjct: 9   TRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTR 68

Query: 80  AWAGNVADLRGPKRAVVGGFVAAALSGLIYLASLLWLDQPAISVAVLLAGRVLLALGESL 139
            +AG +AD  G KR+ + G +A  L+G   L + +         A+L+ GR++L  GES 
Sbjct: 69  GYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQ 128

Query: 140 VITGTMGWGIALVGPQHGGKVMAWLGIAIYAAMA-GLLLGLSINAE 184
           ++TG + WG+ +VGP+H GKVM+W G+AIY A+A G  LGL I++ 
Sbjct: 129 LLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSH 174


>PA1993 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae
           Pseudomonas aeruginosa
          Length = 402

 Score =  112 bits (281), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 71/161 (44%), Positives = 99/161 (61%), Gaps = 1/161 (0%)

Query: 13  PPATAAGTGTSVLQALSPLTLAVFIAFLTIGLQLPVLPLHLKEALGMNATVVGVVVGAQF 72
           PPA  +      LQ +S + +  FI +LTIG+ L VLP ++ + LG  + + G+V+  Q+
Sbjct: 9   PPAQDSARQNVTLQIVS-VVMFTFIGYLTIGIPLAVLPGYVHDDLGYGSVLAGLVISLQY 67

Query: 73  AAALLSRAWAGNVADLRGPKRAVVGGFVAAALSGLIYLASLLWLDQPAISVAVLLAGRVL 132
            A LL+R +AG V D  GPKRAV+ G   +A SGL  L S+     PA+S+A LL GR++
Sbjct: 68  LATLLARPYAGRVIDGLGPKRAVLYGMAGSAASGLFMLLSVAIQGWPALSLASLLVGRLV 127

Query: 133 LALGESLVITGTMGWGIALVGPQHGGKVMAWLGIAIYAAMA 173
           L   ESLV +  +GWGI  VG  H  KV++W GIA Y A+A
Sbjct: 128 LGAAESLVGSAAIGWGIGRVGAPHTAKVISWNGIASYGAIA 168