BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0057.p (391 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso... 606 e-173 XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa ... 548 e-156 NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA... 413 e-115 NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme... 411 e-114 PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae ... 394 e-109 >RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso Ralstonia solanacearum Length = 404 Score = 606 bits (1562), Expect = e-173, Method: Compositional matrix adjust. Identities = 280/390 (71%), Positives = 324/390 (83%), Gaps = 1/390 (0%) Query: 1 MIITSLLDTDLYKFTMMQVVLHHFPGAQVEYKFKCRNEHIDLTPYVDEIRAEIAALCRLR 60 MII SLLDTDLYKFTMMQVVLHHFPGA VEY+FKCRN +DL PY++ IRAEI LC LR Sbjct: 16 MIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAEIRHLCSLR 75 Query: 61 FKEDELNYLRGLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEIQVKGPWLHTIMFE 120 F E EL+YLRGLRFIKSDFVDFLDLFHL+EKYI ++P + +G+I+I + GPWLHTIMFE Sbjct: 76 FTEAELDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGPWLHTIMFE 135 Query: 121 VPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDAELAGCKIADYGTRRRFSRSWH 180 VPVLAIVNEVYF TQ P +EG+ RL +K++ +T L C+IADYGTRRRFS +WH Sbjct: 136 VPVLAIVNEVYFSRTQAHPQWDEGKRRLTEKLASLTRPG-LEDCRIADYGTRRRFSHTWH 194 Query: 181 AEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDSQTFAFEM 240 V+ E + +G +AGTSNV +AM+H++TPLGTMAHEYLQACQ+LGPRLRDSQ FA E Sbjct: 195 EHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSLGPRLRDSQVFALET 254 Query: 241 WAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQHYRDNRV 300 WAREYRGDLGI LSD YG DAFLRD+DM+FCKLFDG RHDSGDPFEWGER+++HY RV Sbjct: 255 WAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERMLKHYEGMRV 314 Query: 301 DPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKMVRCNGQ 360 DP SK L+FSDSLD KV LY RF+ R K+AFGVGTNLTNDLGYTPLQ+V+KMVRCNGQ Sbjct: 315 DPQSKALIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQ 374 Query: 361 PVAKLSDTPSKNMCDDPAYVNYLRQVFQIK 390 PVAKLSD P K MCDDPAY+ YL+QVF ++ Sbjct: 375 PVAKLSDAPEKTMCDDPAYLAYLKQVFGVQ 404 >XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa Xylella fastidiosa 9a5c Length = 394 Score = 548 bits (1411), Expect = e-156, Method: Compositional matrix adjust. Identities = 255/390 (65%), Positives = 312/390 (80%), Gaps = 1/390 (0%) Query: 2 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYKFKCRNEHIDLTPYVDEIRAEIAALCRLRF 61 II SLLDTDLYKFTMMQ VLH +PGAQVEY+FKCR +DL +++EI EI LC LRF Sbjct: 4 IIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCALRF 63 Query: 62 KEDELNYLRGLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEIQVKGPWLHTIMFEV 121 ++EL+YLRGLRF+K DFVDFL LFHL+ KY+ ++ +GEIE+ ++GPWLHTI+FEV Sbjct: 64 SKEELDYLRGLRFMKPDFVDFLGLFHLDRKYLQLRASTQVSGEIELDIRGPWLHTILFEV 123 Query: 122 PVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDAELAGCKIADYGTRRRFSRSWHA 181 P+LAI+NEV+FR T +L+ GRARL K+ ++ ++ C IADYGTRRR+SR WHA Sbjct: 124 PLLAIINEVWFRNTSML-NLDVGRARLDAKVRLLKGESGYEECSIADYGTRRRYSRQWHA 182 Query: 182 EVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDSQTFAFEMW 241 E++ + Q +G +F GTSNV +A Q+ TPLGTMAHEYLQA QALGPRLRDSQ E W Sbjct: 183 ELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLEAW 242 Query: 242 AREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQHYRDNRVD 301 AREYRGDLGI LSDV G+DAFL D+D+YFCKLFDG RHDSGDPF+WGER+I H +R+D Sbjct: 243 AREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRID 302 Query: 302 PSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKMVRCNGQP 361 P +KVLVFSD LD +KV LY F+ R ++AFGVGT+LTNDLG TPLQ+V+KMVRCNGQP Sbjct: 303 PRTKVLVFSDGLDMNKVMRLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQP 362 Query: 362 VAKLSDTPSKNMCDDPAYVNYLRQVFQIKA 391 VAKLSD+P K+MCDDPAY++YLRQVF + A Sbjct: 363 VAKLSDSPGKSMCDDPAYLHYLRQVFGVSA 392 >NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 419 Score = 413 bits (1062), Expect = e-115, Method: Compositional matrix adjust. Identities = 203/398 (51%), Positives = 271/398 (68%), Gaps = 15/398 (3%) Query: 2 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYKFKCRNEHI--DLTPYVDEIRAEIAALCRL 59 II SLLDTDLYKFTM+QVVLH FP Y+F+CRN L +++ E+ ALC+L Sbjct: 21 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEVELDALCQL 80 Query: 60 RFKEDELNYLRGLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEIQVKGPWLHTIMF 119 RF DEL+YLR LRFIKSDFVD+L+LF L +++ V D G + I+++GP + + F Sbjct: 81 RFTHDELDYLRSLRFIKSDFVDYLELFQLQRRFVEVGTD--DKGRLNIRIEGPMIQAMFF 138 Query: 120 EVPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDAELAGCK--------IADYGT 171 E+ +LAIVNE+YFR + +EEG RL+ K + + E+A + I+D+GT Sbjct: 139 EIFILAIVNELYFRRLETPAVIEEGERRLQAKAARL---KEIAAAQNPDEPPFLISDFGT 195 Query: 172 RRRFSRSWHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLR 231 RRR+ +W VI + + GTSNV A + +TP+GTMAHE+LQA QAL RLR Sbjct: 196 RRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLR 255 Query: 232 DSQTFAFEMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERL 291 + Q A E W EYRGDLG+ L+DV GMDAFLRD+D+YF KLFDG RHDSGDP+ WG++ Sbjct: 256 NFQKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYIWGDKA 315 Query: 292 IQHYRDNRVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQVV 351 HY+ ++D +K+L FSD LD ++ AL+ FKDR K FG+GTNLTND+G+TPL +V Sbjct: 316 YAHYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIV 375 Query: 352 MKMVRCNGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQI 389 +K+V CNGQ VAKLSD+P K M ++ ++ YLRQVF + Sbjct: 376 LKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 413 >NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 402 Score = 411 bits (1056), Expect = e-114, Method: Compositional matrix adjust. Identities = 203/399 (50%), Positives = 271/399 (67%), Gaps = 17/399 (4%) Query: 2 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYKFKCRNEHIDLTPYVD---EIRAEIAALCR 58 II SLLDTDLYKFTM+QVVLH FP Y+F+CRN + P D ++ AE+ ALC+ Sbjct: 4 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNAST-VYPLADIREDLEAELDALCQ 62 Query: 59 LRFKEDELNYLRGLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEIQVKGPWLHTIM 118 LRF DEL YLR LRFIKSDFVD+L+LF L +++ + D + I+++GP + + Sbjct: 63 LRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTD--DKDRLNIRIEGPMIQAMF 120 Query: 119 FEVPVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDAELAGCK--------IADYG 170 FE+ +LAIVNE+YFR + +EEG RL+ K + + E+A + I+D+G Sbjct: 121 FEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARL---KEIAAAQNPDEPPFLISDFG 177 Query: 171 TRRRFSRSWHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRL 230 TRRR+ +W VI + + GTSNV A + +TP+GTMAHE+LQA QAL RL Sbjct: 178 TRRRYKLAWQEHVIRTLLEAAPGIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRL 237 Query: 231 RDSQTFAFEMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGER 290 R+ Q A E W EYRGDLG+ L+DV GMDAFLRD+D+YF KLFDG RHDSGDP+ WG++ Sbjct: 238 RNFQKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDK 297 Query: 291 LIQHYRDNRVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDLGYTPLQV 350 HY+ ++D +K+L FSD LD ++ AL+ FKDR K FG+GTNLTND+G+TPL + Sbjct: 298 AYAHYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNI 357 Query: 351 VMKMVRCNGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQI 389 V+K+V CNGQ VAKLSD+P K M ++ ++ YLRQVF + Sbjct: 358 VLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 396 >PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 399 Score = 394 bits (1012), Expect = e-109, Method: Compositional matrix adjust. Identities = 198/394 (50%), Positives = 260/394 (65%), Gaps = 8/394 (2%) Query: 2 IITSLLDTDLYKFTMMQVVLHHFPGAQVEYKFKCRNEHIDLTPYVDEIRAEIAALCRLRF 61 I+ +LLDTD YK TMMQ VLH++P A+VE++F+CRN DL PY+ EIR +I L + Sbjct: 10 IVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNAE-DLRPYLAEIRYQIERLAEVEV 68 Query: 62 KEDELNYLRGLRFIKSDFVDFLDLFHLNEKYITVQPDPAGNGEIEIQVKGPWLHTIMFEV 121 D+L +L + F+K DF+ FL LF N +Y+ + +G++ I+++GPWLH I+FEV Sbjct: 69 TADQLAFLERIPFMKPDFIRFLSLFRFNLRYVHTGIE---DGQLAIRLRGPWLHVILFEV 125 Query: 122 PVLAIVNEVYFRATQRSPDLEEGRARLRKKMSVITDDA---ELAGCKIADYGTRRRFSRS 178 P+LAIV+EV R R LE+ +L +K+ ++ A ELA ++AD+GTRRRFS Sbjct: 126 PLLAIVSEVRNRYRYREVVLEQVGEQLYRKLDWLSAQASSEELAEFQVADFGTRRRFSYR 185 Query: 179 WHAEVIDEMKQHMGDHFAGTSNVMYAMQHDLTPLGTMAHEYLQACQALGPRLRDSQTFAF 238 EV+ +K+ F GTSNV A ++DL P+GTMAHE+L A Q LGPRL DSQ A Sbjct: 186 TQEEVVHILKRDFPGRFVGTSNVHLAREYDLKPIGTMAHEWLMAHQQLGPRLVDSQQAAL 245 Query: 239 EMWAREYRGDLGITLSDVYGMDAFLRDYDMYFCKLFDGARHDSGDPFEWGERLIQHYRDN 298 + W REYRG LGI L+D MDAFL D+D+YF KLFDG RHDSGDP W E+ I HYR Sbjct: 246 DCWVREYRGQLGIALTDCITMDAFLDDFDLYFAKLFDGLRHDSGDPLAWAEKAIAHYRRL 305 Query: 299 RVDPSSKVLVFSDSLDFDKVRALYLRFKDRAKVAFGVGTNLTNDL-GYTPLQVVMKMVRC 357 +DP SK LVFSD LD K L+ + + V+FG+GTNLT D+ G P+ +V+KM C Sbjct: 306 GIDPLSKTLVFSDGLDMPKALQLFRALRGKINVSFGIGTNLTCDIPGVEPMNIVLKMTAC 365 Query: 358 NGQPVAKLSDTPSKNMCDDPAYVNYLRQVFQIKA 391 NG PVAK+SD P K C D +V YLR VF + A Sbjct: 366 NGHPVAKISDAPGKTQCRDENFVAYLRHVFNVPA 399