BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0044.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1607 [GER] COG0697 Permeases of the drug/metabolite transport... 328 7e-90 SMb20885 [GER] COG0697 Permeases of the drug/metabolite transpor... 201 1e-51 PA3358 [GER] COG0697 Permeases of the drug/metabolite transporte... 201 1e-51 AGc4246 [GER] COG0697 Permeases of the drug/metabolite transport... 155 1e-37 mlr3480 [GER] COG0697 Permeases of the drug/metabolite transport... 154 2e-37 >RSc1607 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 307 Score = 328 bits (842), Expect = 7e-90, Method: Compositional matrix adjust. Identities = 186/312 (59%), Positives = 219/312 (70%), Gaps = 18/312 (5%) Query: 1 MMQSAAGARRP--RQLLMSLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLVVL 58 M Q+ + AR P L ++ +P LFVLIWSTGF+VAKFG+PYA P+TFL LRF GVLV L Sbjct: 1 MTQAYSAARMPALDSLFVAAMPWLFVLIWSTGFVVAKFGMPYAEPITFLFLRFVGVLVCL 60 Query: 59 LPLVLLFRAPWPHG-----------RIRHVAVAGVLLQAGYLAGVWCAIKIGMPAGLSAL 107 LPLV + R P P I H+AVAGVL+Q GYL GVW AIK+GMPAG+SAL Sbjct: 61 LPLVWVARVPLPRRAGADADAVDWRTIGHLAVAGVLMQWGYLGGVWEAIKLGMPAGMSAL 120 Query: 108 IVGLQPILTAFAAPLLGESVKGRQWIGLALGLCGVGLVVANKISLIGLSTASIALCVFAL 167 IVG+QPILTA + GE V RQW+GL G+ GVGLVVANK+ L G++ ++ CV AL Sbjct: 121 IVGMQPILTALYVSMRGERVSPRQWLGLLFGIAGVGLVVANKLHLAGVNVTTLGFCVGAL 180 Query: 168 LCITAGTLYQKRYCAHFDLRTGTAIQFMASIVVVLPFAVAVEGLDWQLSNVHWTPQFIGA 227 L ITAGTLYQKR+C FDLR G IQF AS ++ LPF A E V WT IGA Sbjct: 181 LSITAGTLYQKRFCPVFDLRMGACIQFGASALLCLPFMFAFE-----TRAVQWTGPMIGA 235 Query: 228 LLWSVLALSIGAIFLLFALIRRSAATSVTSLLYLTPPTTAVMAWLMFGEAFSLIGALGML 287 L+WSVLALSIGAI LLF LIR+ AAT VTSLLYLTPPTTA MAW +FGE F + ALGM+ Sbjct: 236 LVWSVLALSIGAISLLFMLIRQGAATKVTSLLYLTPPTTAAMAWALFGERFPPLAALGMV 295 Query: 288 VGVIGVAFVVRK 299 + GVA V+R+ Sbjct: 296 IAACGVALVIRR 307 >SMb20885 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 306 Score = 201 bits (512), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 124/294 (42%), Positives = 174/294 (59%), Gaps = 13/294 (4%) Query: 14 LLMSLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLVVLLPLVLLFRAPWPHGR 73 +L L P +FVL+WSTG++VAK+ +A PL FL LR++ +++ + LL A WP Sbjct: 1 MLARLAPAIFVLLWSTGWVVAKYAAIFADPLIFLALRYSFAILLFIGFCLLSGARWPRSA 60 Query: 74 --IRHVAVAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTAFAAP-LLGESVKGR 130 I H V+G+ L YL VW AI G+PA +S +I GLQP++TA AP L+GE + G+ Sbjct: 61 TAIGHAVVSGIFLHGLYLGAVWWAIGQGVPAAISGIIAGLQPLMTAAVAPWLIGEKLAGQ 120 Query: 131 QWIGLALGLCGVGLVVANKISLIGLSTASI-----ALCVFALLCITAGTLYQKRYCAHFD 185 Q +GL LG CG+ L VA K+ I + I A+ V + +T GTLYQKRY D Sbjct: 121 QKLGLILGFCGIALAVAPKMLTIDATATPIHLLPLAVNVLGMAAVTYGTLYQKRYLQTGD 180 Query: 186 LRTGTAIQFMASIVVVLPFAVAVEGLDWQLSNVHWTPQFIGALLWSVLALSIGAIFLLFA 245 +R+ A+Q++ +++V +P A+ +E L V W + + AL WSVL LS+GAI LL Sbjct: 181 IRSIAALQYVGALLVTIPLALMLEDL-----RVTWNIELVAALAWSVLGLSMGAIALLLY 235 Query: 246 LIRRSAATSVTSLLYLTPPTTAVMAWLMFGEAFSLIGALGMLVGVIGVAFVVRK 299 LIRR + SL+YL PP A A L FGEA + +G ++ V GV RK Sbjct: 236 LIRRGQVSRAASLIYLVPPLAAGEAALFFGEALTWPMIIGTVIAVTGVYLTNRK 289 >PA3358 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 201 bits (512), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 144/291 (49%), Positives = 181/291 (62%), Gaps = 11/291 (3%) Query: 10 RPRQLLMSLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLVVLLPLVLLFRAPW 69 R L S +PLLFVL+WSTGF+ AKFGLPYA P TFL +R +L LL APW Sbjct: 2 RTPAWLGSGMPLLFVLLWSTGFLGAKFGLPYAEPFTFLAIRLLLAAALLAAFALLSGAPW 61 Query: 70 PHGRIR---HVAVAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTA-FAAPLLGE 125 P G R HVAVAG+L+ YL GV+ AI+ GM AGL++L+VGLQP+ TA A LGE Sbjct: 62 P-GSARLAGHVAVAGLLVHGLYLGGVFLAIEHGMSAGLTSLLVGLQPLATAALAGIWLGE 120 Query: 126 SVKGRQWIGLALGLCGVGLVVANKISLIGLSTASIALCVFALLCITAGTLYQKRYCAHFD 185 V RQW+GLALGL GV LVV +I G + A + AL IT GTLYQKR+C D Sbjct: 121 QVSRRQWLGLALGLAGVALVVLGRIH-GGADGLAWAAVLVALAAITCGTLYQKRFCGGMD 179 Query: 186 LRTGTAIQFMASIVVVLPFAVAVEGLDWQLSNVHWTPQFIGALLWSVLALSIGAIFLLFA 245 LRTG +Q++AS ++ A+ E + V W+ F+ L W VL LS GA+ LL+ Sbjct: 180 LRTGGVVQYLASGALLGLAALLFESRE-----VQWSTPFVLTLGWLVLGLSFGAVGLLYT 234 Query: 246 LIRRSAATSVTSLLYLTPPTTAVMAWLMFGEAFSLIGALGMLVGVIGVAFV 296 LIR AA+ V SL YL PP TA+ +WL+F E + GML+ ++GVA V Sbjct: 235 LIRHGAASKVASLFYLVPPVTALASWLLFDERLAPAAIGGMLLVMLGVALV 285 >AGc4246 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 354 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 108/299 (36%), Positives = 164/299 (54%), Gaps = 13/299 (4%) Query: 9 RRPRQLLMSLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLVVLLPLVLLFRAP 68 RR L L P +FV +WSTG++ AK+ + Y PLTFL LR+ ++L + Sbjct: 53 RRCSMSLDRLAPAIFVFLWSTGWVTAKYAVYYTGPLTFLCLRYLLAGLLLWAICRFSGIS 112 Query: 69 WPHGR--IRHVAVAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTAFAAP-LLGE 125 WP R + ++GV L YL +W AI G+PA + +I GLQP++TA AA ++GE Sbjct: 113 WPKQRADVLRAILSGVFLHGIYLGMIWWAIGQGVPAAIGGIIAGLQPLMTAVAARFMIGE 172 Query: 126 SVKGRQWIGLALGLCGVGLVVANKI---SLIGLSTA--SIALCVFALLCITAGTLYQKRY 180 + Q GL LG G+ + V K+ +G+S ++A+ V ++ +T GTLYQK+Y Sbjct: 173 RISPLQRAGLLLGFAGIAIAVLPKVMATGALGMSVPLYAVAVNVLGMVSVTYGTLYQKKY 232 Query: 181 CAHFDLRTGTAIQFMASIVVVLPFAVAVEGLDWQLSNVHWTPQFIGALLWSVLALSIGAI 240 ++ +Q++ +++V +PFA+ +E +V W+ L WSV A+SIGA+ Sbjct: 233 VHGGNIMAVATLQYVGALLVTVPFALLLED-----GHVDWSLGLAATLGWSVGAISIGAV 287 Query: 241 FLLFALIRRSAATSVTSLLYLTPPTTAVMAWLMFGEAFSLIGALGMLVGVIGVAFVVRK 299 LL LIRR + SL+YL PP AV A ++FGE + G ++ V GV RK Sbjct: 288 ALLLYLIRRGQVSRAASLIYLVPPLAAVEAAVLFGETLTPAMIAGTVLAVTGVYLANRK 346 >mlr3480 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 303 Score = 154 bits (390), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 13/293 (4%) Query: 13 QLLMSLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRF---TGVLVVLLPLVLLFRAPW 69 Q + +P FV++W+TGFI A++ +P+A P TFL RF +L VL+P++ RA Sbjct: 2 QSIKRFIPATFVVLWATGFIGARYAMPWAEPFTFLAARFVIAAILLAVLMPVLGSKRAT- 60 Query: 70 PHGRIRHVAVAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTA-FAAPLLGESVK 128 H AGVL+ YL V+ AI GMPAG SALIVGLQP++TA A LGE++ Sbjct: 61 -RKEALHATGAGVLMHGVYLGAVFWAIHRGMPAGFSALIVGLQPLITAVLAGKFLGEAIL 119 Query: 129 GRQWIGLALGLCGVGLVVANKISLIG--LSTASIALCVFALLCITAGTLYQKRYCAHFDL 186 R W+GL +GL G+ +V+ K+ +G ++ A++ + ++L ++AGT++QKR+ + DL Sbjct: 120 PRHWLGLGIGLIGIVIVLWPKLGALGGGVTAATLTASLVSVLGMSAGTIWQKRFASGGDL 179 Query: 187 RTGTAIQFMASIVVVLPFAVAVEGLDWQLSNVHWTPQFIGALLWSVLALSIGAIFLLFAL 246 T Q++ +++ A+A E V + I A+ W VL LS+GAIFLL + Sbjct: 180 VAATMWQYVGGASLMILAALAFE-----THTVIINGELIFAMAWLVLVLSLGAIFLLMVM 234 Query: 247 IRRSAATSVTSLLYLTPPTTAVMAWLMFGEAFSLIGALGMLVGVIGVAFVVRK 299 IR + V SL YL P TA++AW +F E + + +GM + GV + Sbjct: 235 IRDGEMSKVASLFYLVPAVTAIIAWALFDEQLNALQIVGMAITTFGVGLATAR 287