BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0041.p (253 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Z0233 [QR] COG0500 SAM-dependent methyltransferases EcZ Escheric... 249 3e-66 ECs0206 [QR] COG0500 SAM-dependent methyltransferases Ecs Escher... 249 3e-66 STM0259 [QR] COG0500 SAM-dependent methyltransferases Sty Salmon... 243 3e-64 yafE [QR] COG0500 SAM-dependent methyltransferases Eco Escherich... 190 3e-48 PA3119 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudom... 184 1e-46 >Z0233 [QR] COG0500 SAM-dependent methyltransferases EcZ Escherichia coli O157:H7 EDL933 Length = 256 Score = 249 bits (637), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 129/251 (51%), Positives = 161/251 (64%) Query: 2 RSHQQVVTEQFGSTAAAYLTSSVHAQGADLQELAQIAASIPGARVLDLGCGGGHASFAVA 61 +SH V +QF S A+ YLTS+VHA G DLQ LA A P A VLD+GCG GHASF A Sbjct: 4 QSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYPDASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSEEMLKVVATAAAGRGLGNLAVRQGSADRLDFPDASFDLVCTRFSAHHW 121 V V+AYDLS +ML VVA AA R L N+ RQG A+ L F D +FD+V +R+SAHHW Sbjct: 64 QNVSTVVAYDLSAQMLDVVAQAAEVRQLKNITTRQGYAESLPFADNAFDIVISRYSAHHW 123 Query: 122 RQLPQALNEAFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + AL E R+LKPGGR IV+D +P + D ++Q +E L DTSHVRN + W +L Sbjct: 124 HDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALCDTSHVRNYASGEWLRL 183 Query: 182 LKAAGFAIAYDKTWKLRLEFDSWVARMRTPQDSITAIRALWQAAPGEVKDYFALDAACSF 241 + A + T KL LEF SWVARMRTP+ + AIR Q+A EV+ YFAL SF Sbjct: 184 INEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEVRTYFALQNDGSF 243 Query: 242 SIDVAMLDARK 252 + D+ M+DA K Sbjct: 244 TSDIIMVDAHK 254 >ECs0206 [QR] COG0500 SAM-dependent methyltransferases Ecs Escherichia coli O157:H7 Length = 256 Score = 249 bits (637), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 129/251 (51%), Positives = 161/251 (64%) Query: 2 RSHQQVVTEQFGSTAAAYLTSSVHAQGADLQELAQIAASIPGARVLDLGCGGGHASFAVA 61 +SH V +QF S A+ YLTS+VHA G DLQ LA A P A VLD+GCG GHASF A Sbjct: 4 QSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYPDASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSEEMLKVVATAAAGRGLGNLAVRQGSADRLDFPDASFDLVCTRFSAHHW 121 V V+AYDLS +ML VVA AA R L N+ RQG A+ L F D +FD+V +R+SAHHW Sbjct: 64 QNVSTVVAYDLSAQMLDVVAQAAEVRQLKNITTRQGYAESLPFADNAFDIVISRYSAHHW 123 Query: 122 RQLPQALNEAFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + AL E R+LKPGGR IV+D +P + D ++Q +E L DTSHVRN + W +L Sbjct: 124 HDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALCDTSHVRNYASGEWLRL 183 Query: 182 LKAAGFAIAYDKTWKLRLEFDSWVARMRTPQDSITAIRALWQAAPGEVKDYFALDAACSF 241 + A + T KL LEF SWVARMRTP+ + AIR Q+A EV+ YFAL SF Sbjct: 184 INEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEVRTYFALQNDGSF 243 Query: 242 SIDVAMLDARK 252 + D+ M+DA K Sbjct: 244 TSDIIMVDAHK 254 >STM0259 [QR] COG0500 SAM-dependent methyltransferases Sty Salmonella typhimurium LT2 Length = 256 Score = 243 bits (620), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 128/251 (50%), Positives = 156/251 (62%) Query: 2 RSHQQVVTEQFGSTAAAYLTSSVHAQGADLQELAQIAASIPGARVLDLGCGGGHASFAVA 61 SH V +QFGS A AYL S+VHA G DL LAQ + A VLD+GCG GHASF A Sbjct: 4 HSHHDNVEKQFGSQANAYLHSAVHAAGRDLARLAQRLSDFSHASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSEEMLKVVATAAAGRGLGNLAVRQGSADRLDFPDASFDLVCTRFSAHHW 121 V+AYDLS ML+VVA AA R L N+ +RQG A++L F DASF++V +R+SAHHW Sbjct: 64 QHANSVVAYDLSASMLEVVAGAAEERHLSNITLRQGYAEKLPFEDASFEVVISRYSAHHW 123 Query: 122 RQLPQALNEAFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + QAL E RVLKPGG I++D +P + D ++Q +E LRDTSHVRN S W + Sbjct: 124 HDVGQALREVNRVLKPGGVLIIMDVMSPGHPVRDIWLQTVEALRDTSHVRNYSSGEWLAM 183 Query: 182 LKAAGFAIAYDKTWKLRLEFDSWVARMRTPQDSITAIRALWQAAPGEVKDYFALDAACSF 241 + A T +L LEF SWV RMRTP + AIR +AP EVK YF L SF Sbjct: 184 VNNAMLVTNTVITDRLSLEFRSWVTRMRTPAPLVEAIRLYQASAPVEVKRYFELQDDGSF 243 Query: 242 SIDVAMLDARK 252 S D ML+A K Sbjct: 244 SSDTIMLEAHK 254 >yafE [QR] COG0500 SAM-dependent methyltransferases Eco Escherichia coli K12 Length = 207 Score = 190 bits (482), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 98/203 (48%), Positives = 124/203 (61%) Query: 50 GCGGGHASFAVAPVVEKVIAYDLSEEMLKVVATAAAGRGLGNLAVRQGSADRLDFPDASF 109 G G +F A V V+AYDLS ML VVA AA R L N+ RQG A+ L F D +F Sbjct: 3 GLPQGRPTFGAAQNVSAVVAYDLSAHMLDVVAQAAEARQLKNITTRQGYAESLPFADNAF 62 Query: 110 DLVCTRFSAHHWRQLPQALNEAFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSH 169 D+V +R+SAHHW + AL E R+LKPGGR IV+D +P + D ++Q +E LRDTSH Sbjct: 63 DIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALRDTSH 122 Query: 170 VRNVSLNSWRKLLKAAGFAIAYDKTWKLRLEFDSWVARMRTPQDSITAIRALWQAAPGEV 229 VRN + W L+ A + T KL LEF SWVARMRTP+ + AIR Q+A EV Sbjct: 123 VRNYASGEWLTLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEV 182 Query: 230 KDYFALDAACSFSIDVAMLDARK 252 + YFAL F+ D+ M+DA K Sbjct: 183 RTYFALQNDGFFTSDIIMVDAHK 205 >PA3119 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudomonas aeruginosa Length = 187 Score = 184 bits (468), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 95/186 (51%), Positives = 119/186 (63%) Query: 67 VIAYDLSEEMLKVVATAAAGRGLGNLAVRQGSADRLDFPDASFDLVCTRFSAHHWRQLPQ 126 ++AYDLS EML VVA +AA RG+ N+ QG A+ L F D FD V +R+S HHWR + Sbjct: 1 MVAYDLSAEMLAVVAQSAAERGMANIRTEQGKAESLPFADGEFDFVFSRYSTHHWRDVGL 60 Query: 127 ALNEAFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKLLKAAG 186 AL E RVLKPGG I +D AAP L DT++Q +ELLRDTSHVRN S W +L AG Sbjct: 61 ALREVRRVLKPGGVAIFVDVAAPGQALPDTFLQTVELLRDTSHVRNYSPAEWARLSGEAG 120 Query: 187 FAIAYDKTWKLRLEFDSWVARMRTPQDSITAIRALWQAAPGEVKDYFALDAACSFSIDVA 246 + + +LRLEF SWV RMRTP+ AIR+L A EV++YF + SFS DV Sbjct: 121 LLVTGSRRQRLRLEFQSWVERMRTPEVFRQAIRSLQLAVGEEVREYFEIADDGSFSTDVL 180 Query: 247 MLDARK 252 +L R+ Sbjct: 181 VLWLRR 186