BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0040.p (366 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1609 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Rso Rals... 342 8e-94 PA0869 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Pae Pseud... 252 1e-66 YPO1176 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Ype Yers... 242 8e-64 VCA0870 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Vch Vibr... 238 2e-62 NMA0962 [M] COG1686 D-alanyl-D-alanine carboxypeptidase NmA Neis... 232 1e-60 >RSc1609 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Rso Ralstonia solanacearum Length = 375 Score = 342 bits (877), Expect = 8e-94, Method: Compositional matrix adjust. Identities = 170/286 (59%), Positives = 208/286 (72%), Gaps = 1/286 (0%) Query: 64 VRKVSVVKGKRHISYQRVSAAP-SIPVVPPVMTAGDLAGLNLTPDPVGLRSNVALVIDQA 122 +RKV V+GKRH+ A P VP T G+ GL TPD + LRS+VALV+DQ Sbjct: 52 IRKVVTVRGKRHVILVERGARPMRAAYVPAAPTLGEAMGLRATPDALALRSSVALVMDQG 111 Query: 123 SSQVLFEKNSSVALPIASVTKLMTALVVVEARLNMEETLTVTDDDVDREKHSSSRLRVGA 182 S VLF+KN+S LPIAS+TKLMTALVV +A M+E L +T+DD D E+++ SRLR G Sbjct: 112 SGDVLFQKNASAVLPIASITKLMTALVVTDAHQPMDELLEITEDDRDFERNTGSRLRYGT 171 Query: 183 TLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMTDTRYVDSTGLSS 242 L+R+D+L +ALMSSENRAASALGR+YPGG PAFVAAMN KA LGMTDT YVDS GLSS Sbjct: 172 MLTREDLLLLALMSSENRAASALGRSYPGGRPAFVAAMNRKAHELGMTDTHYVDSNGLSS 231 Query: 243 QNVASARDLAKLVVAAYNYPIIRQYSTDPKYMVEPSGHAMQYNSSNRLTSNKEWDIGLQK 302 NV+SA DLAK+V+AAY P+IRQ++T ++ V +G + Y ++NRL EWDIGLQK Sbjct: 232 SNVSSAMDLAKIVMAAYKVPLIRQFTTTAEHTVNANGRTLHYVNTNRLVRGGEWDIGLQK 291 Query: 303 TGFINEAGHCLVMYTRIEGRPIVMVFLDSKGRLSHVGDAARMRKWL 348 TGFINEAG CLVM + GR +VMVFLDS G L+ DA R+R WL Sbjct: 292 TGFINEAGRCLVMQANVHGRNVVMVFLDSAGNLTRFADAVRVRNWL 337 >PA0869 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Pae Pseudomonas aeruginosa Length = 310 Score = 252 bits (643), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/277 (46%), Positives = 185/277 (66%), Gaps = 10/277 (3%) Query: 78 YQRVSAAPSIPVVPPVMTAGDLAGLNLTPDPVGLRSNVALVIDQASSQVLFEKNSSVALP 137 + +S A ++ PP AGL L + L S ALV DQ + +VL+ +N + +P Sbjct: 12 FLSLSVATAVSASPP-----PKAGLPLQQE---LASGSALVTDQNTGKVLYSRNPDLVVP 63 Query: 138 IASVTKLMTALVVVEARLNMEETLTVTDDDVDREKHSSSRLRVGATLSRDDMLHIALMSS 197 IAS+TKLMTA+VV++++L ++E L + + + SR+RVG+ +SR DML +ALMSS Sbjct: 64 IASITKLMTAMVVLDSKLPLDEVLPIAISETSEMRGVFSRVRVGSQISRRDMLLLALMSS 123 Query: 198 ENRAASALGRNYPGGLPAFVAAMNAKARSLGMTDTRYVDSTGLSSQNVASARDLAKLVVA 257 ENRAA++L +NYPGG AFV AMNAKA +LGM +TRYV+ TGLS NV++ARDL +L+VA Sbjct: 124 ENRAAASLAQNYPGGKNAFVKAMNAKAHALGMKNTRYVEPTGLSLHNVSTARDLTRLLVA 183 Query: 258 AYNYPIIRQYSTDPKYMV--EPSGHAMQYNSSNRLTSNKEWDIGLQKTGFINEAGHCLVM 315 + YP++ Q+ST P+ V + + + ++N L +NK W+I L KTGF NEAGHCLVM Sbjct: 184 SRQYPLLSQWSTTPEKTVAFRHPNYTLGFRNTNHLINNKTWNIQLTKTGFTNEAGHCLVM 243 Query: 316 YTRIEGRPIVMVFLDSKGRLSHVGDAARMRKWLVDDQ 352 T I P+ +V LD+ G+ +H DA R+R+WL Q Sbjct: 244 RTTINRSPVNLVVLDAFGKYTHFADATRLRRWLETGQ 280 >YPO1176 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Ype Yersinia pestis Length = 311 Score = 242 bits (618), Expect = 8e-64, Method: Compositional matrix adjust. Identities = 120/244 (49%), Positives = 170/244 (69%), Gaps = 4/244 (1%) Query: 108 PVGLRSNVALVIDQASSQVLFEKNSSVALPIASVTKLMTALVVVEARLNMEETLTVTDDD 167 P+ L S A+V+D +++V++ N+ +PIAS+TKLMTA+VV++A+L ++E L+V D Sbjct: 39 PLELASGSAMVVDLQTNKVIYANNADKVVPIASITKLMTAMVVLDAKLPLDEILSVDIDQ 98 Query: 168 VDREKHSSSRLRVGATLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSL 227 K SR+RV + +SR DML + LMSSENRAA++L +YPGG AF+ AMNAKA+SL Sbjct: 99 TKELKGVFSRVRVNSEISRKDMLLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSL 158 Query: 228 GMTDTRYVDSTGLSSQNVASARDLAKLVVAAYNYPIIRQYSTDPKYMV---EPSGHAMQY 284 GM T YV+ TGLS NV++ARDLAKL++A YP+I Q ST + M EP+ + + + Sbjct: 159 GMNSTHYVEPTGLSINNVSTARDLAKLLMATKQYPLIGQLSTTTEKMATFREPN-YTLPF 217 Query: 285 NSSNRLTSNKEWDIGLQKTGFINEAGHCLVMYTRIEGRPIVMVFLDSKGRLSHVGDAARM 344 ++N L N +W+I L KTGF N+AGHCLVM T I RP+ +V LD+ G+ +H DA R+ Sbjct: 218 RNTNHLVYNDKWNIQLTKTGFTNQAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRL 277 Query: 345 RKWL 348 R W+ Sbjct: 278 RSWI 281 >VCA0870 [M] COG1686 D-alanyl-D-alanine carboxypeptidase Vch Vibrio cholerae Length = 316 Score = 238 bits (606), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 119/251 (47%), Positives = 169/251 (67%), Gaps = 2/251 (0%) Query: 100 AGLNLTPDPVGLRSNVALVIDQASSQVLFEKNSSVALPIASVTKLMTALVVVEARLNMEE 159 AG+ T L +N ALVID ++++++ N PIASVTKLMTA+V ++A+L M+ Sbjct: 34 AGVKKTVKKQELSANSALVIDLKTNEIIYSNNPDAVKPIASVTKLMTAIVTLDAKLPMDA 93 Query: 160 TLTVTDDDVDREKHSSSRLRVGATLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAA 219 L +T D K SR+++G+ +SR DML + LMSSENRAA++L +YPGG AF+ A Sbjct: 94 KLPITIKDAKEMKGVHSRVKIGSEISRKDMLLLTLMSSENRAAASLAHHYPGGYKAFIKA 153 Query: 220 MNAKARSLGMTDTRYVDSTGLSSQNVASARDLAKLVVAAYNYPIIRQYSTDPKYMVEPSG 279 MNAKA++LGM +TR+V+ TGLS++NV++ARDL L+ A+ YP++ + S K V S Sbjct: 154 MNAKAKALGMKNTRFVEPTGLSAKNVSTARDLVVLLKASKKYPLLGKLSATDKKTVTFSK 213 Query: 280 --HAMQYNSSNRLTSNKEWDIGLQKTGFINEAGHCLVMYTRIEGRPIVMVFLDSKGRLSH 337 + + + ++NRL N W I L KTGF N AGHCLVM T++ R + V LD+KG+LS Sbjct: 214 PRYTLDFRNTNRLVHNDNWKIDLTKTGFTNAAGHCLVMRTQMGRRQVAFVVLDTKGKLSP 273 Query: 338 VGDAARMRKWL 348 VGDA R+R W+ Sbjct: 274 VGDANRLRTWI 284 >NMA0962 [M] COG1686 D-alanyl-D-alanine carboxypeptidase NmA Neisseria meningitidis Z2491 Length = 312 Score = 232 bits (591), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 112/242 (46%), Positives = 166/242 (68%) Query: 111 LRSNVALVIDQASSQVLFEKNSSVALPIASVTKLMTALVVVEARLNMEETLTVTDDDVDR 170 L S ALV++ + Q+L++KN+ +PIAS++KLM+A+VV++A L+M ET+T+T D++DR Sbjct: 70 LSSQSALVVNNKTGQILYQKNADRIMPIASISKLMSAMVVLDANLDMNETVTITPDEIDR 129 Query: 171 EKHSSSRLRVGATLSRDDMLHIALMSSENRAASALGRNYPGGLPAFVAAMNAKARSLGMT 230 K + SRL +G L+R ++LH++LMSSENRA ALGR YPGG+ AFVAAMN KA+SLGM Sbjct: 130 IKGTGSRLAIGTALTRKELLHLSLMSSENRATHALGRTYPGGMGAFVAAMNRKAQSLGMY 189 Query: 231 DTRYVDSTGLSSQNVASARDLAKLVVAAYNYPIIRQYSTDPKYMVEPSGHAMQYNSSNRL 290 +R+ + TGL+ QNV++A+DL+ +V AA YP IR ST V+ Y +SN L Sbjct: 190 GSRFYEPTGLNFQNVSTAKDLSLMVNAAAQYPQIRTNSTSNYASVQTKNGQQNYKNSNAL 249 Query: 291 TSNKEWDIGLQKTGFINEAGHCLVMYTRIEGRPIVMVFLDSKGRLSHVGDAARMRKWLVD 350 W+I LQKTG+I EAG +V+ I+ +P+ +V L+S + V DA ++ W++ Sbjct: 250 VREGMWNIELQKTGYIREAGRSMVVKANIQNQPVTIVLLNSPTSATRVNDARKIESWMLQ 309 Query: 351 DQ 352 + Sbjct: 310 QR 311