BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0012.p (408 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3806 [E] COG4177 ABC-type branched-chain amino acid transport... 464 e-130 PA1072 [E] COG4177 ABC-type branched-chain amino acid transport ... 448 e-126 STM3562 [E] COG4177 ABC-type branched-chain amino acid transport... 434 e-121 livM [E] COG4177 ABC-type branched-chain amino acid transport sy... 430 e-120 ZlivM [E] COG4177 ABC-type branched-chain amino acid transport s... 429 e-120 >YPO3806 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Ype Yersinia pestis Length = 428 Score = 464 bits (1194), Expect = e-130, Method: Compositional matrix adjust. Identities = 243/411 (59%), Positives = 296/411 (72%), Gaps = 8/411 (1%) Query: 4 TFKNAVAAALVTAVLTIPLLGMQLQLEGYRVVLN----THWTPVLVAVLAVFLFQLARPA 59 F NA+ ++ V VL ++G+QLQL+G R+V+ W + L VF FQL RP Sbjct: 5 NFVNAIISSFVLLVLASFVMGLQLQLDGTRLVVQGASEVRWLWIGAGCLVVFCFQLVRPL 64 Query: 60 LARTSAGIKLPA--LPRMQPGQQRAAVLILLMAALV--WPFFGSRGYVDVMTLALIYVVL 115 + + + PA LP R +L ++ WPF SRG VD+ TL LIYV+L Sbjct: 65 IQQGIKKVSGPAWVLPSFDGTTPRQKLLAAVVIIAAVAWPFLVSRGSVDIATLTLIYVML 124 Query: 116 GLGLNIVVGFAGLLDLGYVGFYAVGAYTYALCNQYFGLSFWECVPLSAAAAALFGFLLGF 175 GLGLN+VVG +GLL LGY GFYA+GAYTYAL N Y+GL FWE +PL+ AAL GFLLGF Sbjct: 125 GLGLNVVVGLSGLLVLGYGGFYAIGAYTYALLNHYYGLGFWESLPLAGITAALSGFLLGF 184 Query: 176 PVLRLRGDYLAIVTLGFGEIIRLLLNNMTSLTGGPDGISGIPKPTVFGVVMARNPLTEDG 235 PVLRLRGDYLAIVTLGFGEI+R+LL N T +TGGP+GIS IPKPT+FG+ +R Sbjct: 185 PVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTLFGLEFSRTAKDGGW 244 Query: 236 TTFHQLLGLTYQGGHMVIFLYFLALLMVLFTYFVTSRLLRMPMGRAWEALREDEIACRSL 295 TFH GLTY H +IFLY +ALL+V+ T FV +RLLRMP+GRAWEALREDEIACRSL Sbjct: 245 DTFHNFFGLTYDPSHRIIFLYLVALLLVILTLFVINRLLRMPLGRAWEALREDEIACRSL 304 Query: 296 GINPTRVKLSAFTLGAAFAGLAGSFFAARQGLVTPESFTFIESALILAIVVLGGMGSQLG 355 G++PT++KL+AFT+ AAFAG AG+ FAARQG V+PESFTF+ESA +LAIVVLGGMGSQ Sbjct: 305 GLSPTKIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFVESAFVLAIVVLGGMGSQFA 364 Query: 356 VILAAILLTVLPELARSFAEYRMLIFGLVMVLMMMWRPQGLLPATRPHVEL 406 VILAA+LL V EL R Y ML+ G +MVLMM+WRPQGLLP RP ++L Sbjct: 365 VILAAVLLVVSRELMRDLNAYSMLLLGALMVLMMIWRPQGLLPMKRPQLKL 415 >PA1072 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Pae Pseudomonas aeruginosa Length = 417 Score = 448 bits (1153), Expect = e-126, Method: Compositional matrix adjust. Identities = 258/418 (61%), Positives = 315/418 (75%), Gaps = 15/418 (3%) Query: 1 MPETFKNAVAAALVTAVLTIPLLGMQLQLEGYRVVL-----NTHWTPVLVAVLAVFLFQL 55 M ++ K A+ +AL+ +++ P+LG++L+ G ++ + T WT + A LA+F++QL Sbjct: 1 MSQSLKRALFSALLVILVSYPILGLKLRTVGIKLEVLGADAQTLWT-IAAAALAMFVWQL 59 Query: 56 AR---PALARTSAGIKLPALPRMQ----PGQQRAAVLILLMAALVWPFFGSRGYVDVMTL 108 R P G K+ P QR AVL L++ A VWPFF SRG VD+ TL Sbjct: 60 FRDRIPLKLGRGVGYKVNGSGLKNFLSLPSTQRWAVLALVVVAFVWPFFASRGAVDIATL 119 Query: 109 ALIYVVLGLGLNIVVGFAGLLDLGYVGFYAVGAYTYALCNQYFGLSFWECVPLSAAAAAL 168 LIYV+LG+GLNIVVG AGLLDLGYVGFYAVGAYTYAL +Y G FW +P++ AAL Sbjct: 120 ILIYVMLGIGLNIVVGLAGLLDLGYVGFYAVGAYTYALLAEYAGFGFWTALPIAGMMAAL 179 Query: 169 FGFLLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNMTSLTGGPDGISGIPKPTVFGVVMAR 228 FGFLLGFPVLRLRGDYLAIVTLGFGEIIR+LL NMT +TGGP+GI IPKPT+FG+ R Sbjct: 180 FGFLLGFPVLRLRGDYLAIVTLGFGEIIRILLRNMTEITGGPNGIGSIPKPTLFGLTFER 239 Query: 229 NPLTEDGTTFHQLLGLTYQGGHMVIFLYFLALLMVLFTYFVTSRLLRMPMGRAWEALRED 288 E TFH+ G+ Y + VI LY +ALL+VL FV +RL+RMP+GRAWEALRED Sbjct: 240 RA-PEGMQTFHEFFGIAYNTNYKVILLYVVALLLVLLALFVINRLMRMPIGRAWEALRED 298 Query: 289 EIACRSLGINPTRVKLSAFTLGAAFAGLAGSFFAARQGLVTPESFTFIESALILAIVVLG 348 E+ACR+LG+NPT VKLSAFT+GA+FAG AGSFFAARQGLVTPESFTFIESA+ILAIVVLG Sbjct: 299 EVACRALGLNPTIVKLSAFTIGASFAGFAGSFFAARQGLVTPESFTFIESAMILAIVVLG 358 Query: 349 GMGSQLGVILAAILLTVLPELARSFAEYRMLIFGLVMVLMMMWRPQGLLPATRPHVEL 406 GMGSQLGVILAA+++ +L E+ R F EYRMLIFGL M++MM+WRPQGLLP RPH+EL Sbjct: 359 GMGSQLGVILAAVVMVLLQEM-RGFNEYRMLIFGLTMIVMMIWRPQGLLPMQRPHLEL 415 >STM3562 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Sty Salmonella typhimurium LT2 Length = 425 Score = 434 bits (1117), Expect = e-121, Method: Compositional matrix adjust. Identities = 236/412 (57%), Positives = 299/412 (72%), Gaps = 12/412 (2%) Query: 9 VAAALVTA----VLTIPLLGMQLQLEGYRVVLNT----HWTPVLVAVLAVFLFQLARPAL 60 +A AL +A VL +G+QL+L+G ++V++T W + + VF FQL RP Sbjct: 6 IAMALFSAAMFFVLAGVFMGVQLELDGTKLVVDTAADIRWQWIFIGTAVVFFFQLLRPMF 65 Query: 61 ARTSAGIKLPA--LPRMQPG--QQRAAVLILLMAALVWPFFGSRGYVDVMTLALIYVVLG 116 + + P LP + +Q+ ++ LL+ A+ WPF SRG VD+ T+ +IY++LG Sbjct: 66 QKAVKHVSGPKFILPAIDGSTVKQKLFLMALLVIAVAWPFMVSRGSVDIATMTMIYIILG 125 Query: 117 LGLNIVVGFAGLLDLGYVGFYAVGAYTYALCNQYFGLSFWECVPLSAAAAALFGFLLGFP 176 LGLN+VVG +GLL LGY GFYA+GAYT+AL N Y+GL FW C+PL+ +A GFLLGFP Sbjct: 126 LGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYYGLGFWTCLPLAGLVSAAAGFLLGFP 185 Query: 177 VLRLRGDYLAIVTLGFGEIIRLLLNNMTSLTGGPDGISGIPKPTVFGVVMARNPLTEDGT 236 VLRLRGDYLAIVTLGFGEI+R+LL N T +TGGP+GIS IPKPT+FG+ +R+ Sbjct: 186 VLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTLFGLEFSRSTREGGWD 245 Query: 237 TFHQLLGLTYQGGHMVIFLYFLALLMVLFTYFVTSRLLRMPMGRAWEALREDEIACRSLG 296 TF G+ Y VIFLY +ALL+V+ + FV +RLLRMP+GRAWEALREDEIACRSLG Sbjct: 246 TFSNFFGVKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIACRSLG 305 Query: 297 INPTRVKLSAFTLGAAFAGLAGSFFAARQGLVTPESFTFIESALILAIVVLGGMGSQLGV 356 ++PTR+KL+AFT+ AAFAG AG+ FAARQG V+PESFTF ESA +LAIVVLGGMGSQ V Sbjct: 306 LSPTRIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMGSQFAV 365 Query: 357 ILAAILLTVLPELARSFAEYRMLIFGLVMVLMMMWRPQGLLPATRPHVELPQ 408 ILAA+LL V EL R F EY ML+ G +MVLMM+WRPQGLLP TRP ++L Sbjct: 366 ILAAVLLVVSRELMRDFNEYSMLMLGGLMVLMMIWRPQGLLPMTRPQLKLKS 417 >livM [E] COG4177 ABC-type branched-chain amino acid transport system, permease component Eco Escherichia coli K12 Length = 425 Score = 430 bits (1105), Expect = e-120, Method: Compositional matrix adjust. Identities = 240/412 (58%), Positives = 299/412 (72%), Gaps = 12/412 (2%) Query: 9 VAAALVTA----VLTIPLLGMQLQLEGYRVVLNT----HWTPVLVAVLAVFLFQLARPAL 60 +A AL++A VL +G+QL+L+G ++V++T W V + VF FQL RPA Sbjct: 6 IAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASDVRWQWVFIGTAVVFFFQLLRPAF 65 Query: 61 ARTSAGIKLPA--LPRMQPG--QQRAAVLILLMAALVWPFFGSRGYVDVMTLALIYVVLG 116 + + P LP + +Q+ ++ LL+ A+ WPF SRG VD+ TL +IY++LG Sbjct: 66 QKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVAWPFMVSRGTVDIATLTMIYIILG 125 Query: 117 LGLNIVVGFAGLLDLGYVGFYAVGAYTYALCNQYFGLSFWECVPLSAAAAALFGFLLGFP 176 LGLN+VVG +GLL LGY GFYA+GAYT+AL N Y+GL FW C+P++ AA GFLLGFP Sbjct: 126 LGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYYGLGFWTCLPIAGLMAAAAGFLLGFP 185 Query: 177 VLRLRGDYLAIVTLGFGEIIRLLLNNMTSLTGGPDGISGIPKPTVFGVVMARNPLTEDGT 236 VLRLRGDYLAIVTLGFGEI+R+LL N T +TGGP+GIS IPKPT+FG+ +R Sbjct: 186 VLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTLFGLEFSRTAREGGWD 245 Query: 237 TFHQLLGLTYQGGHMVIFLYFLALLMVLFTYFVTSRLLRMPMGRAWEALREDEIACRSLG 296 TF GL Y VIFLY +ALL+V+ + FV +RLLRMP+GRAWEALREDEIACRSLG Sbjct: 246 TFSNFFGLKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIACRSLG 305 Query: 297 INPTRVKLSAFTLGAAFAGLAGSFFAARQGLVTPESFTFIESALILAIVVLGGMGSQLGV 356 ++P R+KL+AFT+ AAFAG AG+ FAARQG V+PESFTF ESA +LAIVVLGGMGSQ V Sbjct: 306 LSPRRIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMGSQFAV 365 Query: 357 ILAAILLTVLPELARSFAEYRMLIFGLVMVLMMMWRPQGLLPATRPHVELPQ 408 ILAAILL V EL R F EY ML+ G +MVLMM+WRPQGLLP TRP ++L Sbjct: 366 ILAAILLVVSRELMRDFNEYSMLMLGGLMVLMMIWRPQGLLPMTRPQLKLKN 417 >ZlivM [E] COG4177 ABC-type branched-chain amino acid transport system, permease component EcZ Escherichia coli O157:H7 EDL933 Length = 425 Score = 429 bits (1103), Expect = e-120, Method: Compositional matrix adjust. Identities = 240/412 (58%), Positives = 298/412 (72%), Gaps = 12/412 (2%) Query: 9 VAAALVTA----VLTIPLLGMQLQLEGYRVVLNT----HWTPVLVAVLAVFLFQLARPAL 60 +A AL++A VL +G+QL+L+G ++V++T W V + VF FQL RPA Sbjct: 6 IAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASDIRWQWVFIGTAVVFFFQLLRPAF 65 Query: 61 ARTSAGIKLPA--LPRMQPG--QQRAAVLILLMAALVWPFFGSRGYVDVMTLALIYVVLG 116 + + P LP + +Q+ ++ LL+ A+ WPF SRG VD+ TL +IY++LG Sbjct: 66 QKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVAWPFMVSRGTVDIATLTMIYIILG 125 Query: 117 LGLNIVVGFAGLLDLGYVGFYAVGAYTYALCNQYFGLSFWECVPLSAAAAALFGFLLGFP 176 LGLN+VVG +GLL LGY GFYA+GAYT+AL N Y+GL FW C+P++ AA GFLLGFP Sbjct: 126 LGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYYGLGFWTCLPIAGLMAAAAGFLLGFP 185 Query: 177 VLRLRGDYLAIVTLGFGEIIRLLLNNMTSLTGGPDGISGIPKPTVFGVVMARNPLTEDGT 236 VLRLRGDYLAIVTLGFGEI+R+LL N T +TGGP+GIS IPKPT FG+ +R Sbjct: 186 VLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTFFGLEFSRTAREGGWD 245 Query: 237 TFHQLLGLTYQGGHMVIFLYFLALLMVLFTYFVTSRLLRMPMGRAWEALREDEIACRSLG 296 TF GL Y VIFLY +ALL+V+ + FV +RLLRMP+GRAWEALREDEIACRSLG Sbjct: 246 TFSNFFGLKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIACRSLG 305 Query: 297 INPTRVKLSAFTLGAAFAGLAGSFFAARQGLVTPESFTFIESALILAIVVLGGMGSQLGV 356 ++P R+KL+AFT+ AAFAG AG+ FAARQG V+PESFTF ESA +LAIVVLGGMGSQ V Sbjct: 306 LSPRRIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMGSQFAV 365 Query: 357 ILAAILLTVLPELARSFAEYRMLIFGLVMVLMMMWRPQGLLPATRPHVELPQ 408 ILAAILL V EL R F EY ML+ G +MVLMM+WRPQGLLP TRP ++L Sbjct: 366 ILAAILLVVSRELMRDFNEYSMLMLGGLMVLMMIWRPQGLLPMTRPQLKLKN 417