BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0003.p (397 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 272 1e-72 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 266 4e-71 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 266 8e-71 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 266 8e-71 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 264 2e-70 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 272 bits (695), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 149/299 (49%), Positives = 194/299 (64%), Gaps = 3/299 (1%) Query: 11 SPDHHDGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQ 70 +P DGLP QR AI + LG+ +AVLDG+IAN+ALP +A DL S A +IWV+N+YQ Sbjct: 2 NPSTSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQ 61 Query: 71 IAMAVCLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGI 130 +A+ + LL +ASLG++IGYRRVY GL +F++ SL CA S + L+ ARVLQG GAA + Sbjct: 62 LAITISLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAAL 121 Query: 131 LSVNTALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGL 190 +SVNTALIR IYP QLGR IG N L+ +A GP++A +L + SW WLF +N+P+GL Sbjct: 122 MSVNTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGL 181 Query: 191 AALAVGSRALPFNPLSA--RRFDRQSALLCMAFIGLLLYTIDAIGHLQGGWVVAGCAL-L 247 A +G + LP N + RFD S +L GLL+ I Q V+A + L Sbjct: 182 LAWCLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVAL 241 Query: 248 TAISLALLLKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLG 306 I + + + S P+LP+DLLRIP+FALSIGTS SFAAQM V LPF LQ LG Sbjct: 242 LLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLG 300 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 266 bits (681), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 147/294 (50%), Positives = 194/294 (65%), Gaps = 3/294 (1%) Query: 16 DGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAV 75 DGLP QR AI T+V+G+S+AVLDG+IAN+ALP +ATDL A+ A +IWV+N+YQIA+ + Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 76 CLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNT 135 LL + LG++ GYRR+Y GL +F L+SL CA S + L+LARV+QG G A ++SVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNT 163 Query: 136 ALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAV 195 ALIR IYP R LGR +G N+ + +A GPT+A IL + SW WLFLIN+PLG+ AL + Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 196 GSRALPFN--PLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISL 252 R LP N S RFD SA++ GLL+ + Q + A ++ + + Sbjct: 224 AMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVVGI 283 Query: 253 ALLLKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLG 306 + + S P+LP+DLLRIPLF+LSI TS CSF AQM V LPF LQ LG Sbjct: 284 FFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLG 337 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 266 bits (679), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 147/294 (50%), Positives = 194/294 (65%), Gaps = 3/294 (1%) Query: 16 DGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAV 75 DGLP QR AI T+V+G+S+AVLDG+IAN+ALP +ATDL A+ A +IWV+N+YQIA+ + Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 76 CLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNT 135 LL + LG++ GYRR+Y GL +F L+SL CA S + L+LARV+QG G A ++SVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSVNT 163 Query: 136 ALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAV 195 ALIR IYP R LGR +G N+ + +A GPT+A IL + SW WLFLIN+PLG+ AL + Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 196 GSRALPFN--PLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISL 252 R LP N S RFD SA++ GLL+ + Q + A ++ + + Sbjct: 224 AMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVVGI 283 Query: 253 ALLLKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLG 306 + + S P+LP+DLLRIPLF+LSI TS CSF AQM V LPF LQ LG Sbjct: 284 FFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLG 337 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 266 bits (679), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 147/294 (50%), Positives = 194/294 (65%), Gaps = 3/294 (1%) Query: 16 DGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAV 75 DGLP QR AI T+V+G+S+AVLDG+IAN+ALP +ATDL A+ A +IWV+N+YQIA+ + Sbjct: 44 DGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVI 103 Query: 76 CLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNT 135 LL + LG++ GYRR+Y GL +F L+SL CA S + L+LARV+QG G A ++SVNT Sbjct: 104 SLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSVNT 163 Query: 136 ALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAV 195 ALIR IYP R LGR +G N+ + +A GPT+A IL + SW WLFLIN+PLG+ AL + Sbjct: 164 ALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLL 223 Query: 196 GSRALPFN--PLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISL 252 R LP N S RFD SA++ GLL+ + Q + A ++ + + Sbjct: 224 AMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVVGI 283 Query: 253 ALLLKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLG 306 + + S P+LP+DLLRIPLF+LSI TS CSF AQM V LPF LQ LG Sbjct: 284 FFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLG 337 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 264 bits (675), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 147/294 (50%), Positives = 194/294 (65%), Gaps = 3/294 (1%) Query: 16 DGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAV 75 DGLP QR AI T+++G+S+AVLDG+IAN+ALP +ATDL AS A +IW++N+YQIA+ V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 76 CLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNT 135 LL L+ LG++ GY R+Y GL +F L+SL CA S + L+LAR+ QG G A ++SVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 136 ALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAV 195 ALIR IYP R LGR +G N+ + +A GPT+A IL + SW WLFLIN+PLG+ AL + Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 196 GSRALPFNPL--SARRFDRQSALLCMAFIGLLLYTIDAIGHLQGGWVVAGCALLTAISLA 253 R LP N + RFD SA++ GLL+ + Q ++ L+ + Sbjct: 187 AIRFLPANIAHDTKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVVVGF 246 Query: 254 LLLKLQ-SPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLG 306 ++ Q S P+LP+DLLRIPLF+LSIGTS CSF AQM V LPF LQ LG Sbjct: 247 FFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLG 300