BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0091.p (338 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3119 [KE] COG1167 Transcriptional regulators containing a DNA... 293 3e-79 YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA... 276 6e-74 RSc0030 [KE] COG1167 Transcriptional regulators containing a DNA... 263 4e-70 alr4738 [KE] COG1167 Transcriptional regulators containing a DNA... 238 2e-62 BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-... 225 9e-59 >RSc3119 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 488 Score = 293 bits (750), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 163/327 (49%), Positives = 218/327 (66%), Gaps = 2/327 (0%) Query: 3 LAYGDPLGEPALREAIAQYLRVARGVRCEAGQVVVTEGSQGALSLCVRLFANPGERAWLE 62 L Y G ALR+AIA+YLRV+RGVRCEA QV +T+G+Q +L LC R A+ + AW+E Sbjct: 156 LGYMPVEGNAALRQAIAEYLRVSRGVRCEARQVFITDGTQNSLDLCARTLADADDTAWIE 215 Query: 63 DPGYGGVRAAFHAGDMKIRSMPVDEEGILIAERAWRS-PPRLIHVTPSHQYPTGAVLSLA 121 +PGY G R AF A ++++ +PVD +G+ WR PPRLI++TPSHQYP GAV+SL Sbjct: 216 NPGYSGARHAFQAANLRLAPIPVDADGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLE 275 Query: 122 RRLALIARAREHGCWIIEDDYDSDFRHHGHPIPAMQGLVPDAPVLYVGTFSKTLFPGLRI 181 RRLAL+A+AR G WIIEDDYDS+FRH G P+ A+QGL DAPV+Y+GTFSK +FP LR+ Sbjct: 276 RRLALLAQARAAGAWIIEDDYDSEFRHQGAPLSAVQGLTEDAPVIYLGTFSKVMFPALRL 335 Query: 182 GFLVLPSSVGEGAGRALSELLRGGHRLEQLALAEFMAGGQFARHLGRMKRLYRERQQALR 241 GF+V+P ++ R L+ G EQLALA+F+ G F RHL RM+RLY ER+ AL+ Sbjct: 336 GFMVVPPALAPVLRRTAGALMLRGRVAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQ 395 Query: 242 AALQAQLPE-FGISGGDSGLHLTLRLPPDCPDTAVSTAARAAGMNVGALSSFSAGPAQAG 300 AL+ +L +SGG G+HL+ RL DT VS RA G+ + LS F + Sbjct: 396 GALERRLRGLLTVSGGAGGMHLSARLDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGP 455 Query: 301 NNGLVIGYGNTSHEQYAALIRRLAGIV 327 NGLV+GYG + L+++L ++ Sbjct: 456 YNGLVLGYGAVDAGRMDRLVQQLGQVI 482 >YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ype Yersinia pestis Length = 501 Score = 276 bits (705), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 143/329 (43%), Positives = 205/329 (62%), Gaps = 4/329 (1%) Query: 3 LAYGDPLGEPALREAIAQYLRVARGVRCEAGQVVVTEGSQGALSLCVRLFANPGERAWLE 62 L Y G P L++A+A YLR+AR V C Q+++T G+ AL L ++ +PG+ AW+E Sbjct: 167 LTYSVHGGCPQLQQALADYLRIARSVSCTPDQILITAGTHQALDLLAKMLCDPGDHAWIE 226 Query: 63 DPGYGGVRAAFHAGDMKIRSMPVDEEGILIAERAWRS-PPRLIHVTPSHQYPTGAVLSLA 121 +P Y G+R +++ + VDE G+ + + S PRLI VTPSHQYP G+V+SL Sbjct: 227 EPSYWGIRNVLTINGIEVIPVSVDENGMDPLDLPFESRSPRLICVTPSHQYPLGSVMSLT 286 Query: 122 RRLALIARAREHGCWIIEDDYDSDFRHHGHPIPAMQGLVPDAPVLYVGTFSKTLFPGLRI 181 RR ++A A++H CW++EDDYDS+FR G PIPA+QGL+PDAPV+Y+GTFSKTL+PG+RI Sbjct: 287 RRQRILALAQQHNCWVVEDDYDSEFRFSGSPIPALQGLIPDAPVIYLGTFSKTLYPGMRI 346 Query: 182 GFLVLPSSVGEGAGRALSELLRGGHRLEQLALAEFMAGGQFARHLGRMKRLYRERQQALR 241 ++VLP + + A SEL RGG+ + QL LAEF+ G +A H+ RM+ +Y +R+ AL Sbjct: 347 SYMVLPRPLAQQFKVAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGKRRAALV 406 Query: 242 AALQAQL-PEFGISGGDSGLHLTLRLPPDCPDTAVSTAARAAGMNVGALSSFSAGPAQAG 300 ++ QL F G++GLHL L LP D A+S G+ V ALS + Sbjct: 407 GMIKQQLGGSFLAEYGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYL--KSPP 464 Query: 301 NNGLVIGYGNTSHEQYAALIRRLAGIVRR 329 GL++GYG E A+ + +RR Sbjct: 465 RRGLLLGYGCVPEEAMEAVFAPIVSYLRR 493 >RSc0030 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 509 Score = 263 bits (672), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 144/319 (45%), Positives = 195/319 (61%), Gaps = 5/319 (1%) Query: 14 LREAIAQYLRVARGVRCEAGQVVVTEGSQGALSLCVRLFANPGERAWLEDPGYGGVRAAF 73 LR A+A YLR ARGVRCE Q+++T G +L L +L + G+ AW+EDPGY GVR+ Sbjct: 189 LRTALADYLRTARGVRCEPEQIIITAGIHPSLQLIAQLLCDAGDSAWIEDPGYWGVRSVL 248 Query: 74 HAGDMKIRSMPVDEEGILIAERAWRS---PPRLIHVTPSHQYPTGAVLSLARRLALIARA 130 A ++ +PVD+EG+ R PP+L+ V+PSHQYP G+V+SLARR L+A A Sbjct: 249 TAAGVRTVPLPVDDEGMRFEAAGRRQRGRPPKLMVVSPSHQYPLGSVMSLARRRQLLATA 308 Query: 131 REHGCWIIEDDYDSDFRHHGHPIPAMQGLVPDAPVLYVGTFSKTLFPGLRIGFLVLPSSV 190 + WI+EDDYDS+FR+ P+P++QGL VLY+GTFSK LFP LRIG+LV+P ++ Sbjct: 309 QATDAWIVEDDYDSEFRYGSRPLPSLQGLDEGGRVLYMGTFSKVLFPSLRIGYLVVPPAL 368 Query: 191 GEGAGRALSELLRGGHRLEQLALAEFMAGGQFARHLGRMKRLYRERQQALRAALQAQLPE 250 E LSE+ RGG L Q LAEF+A G F H+ RM+ +Y ER++ L A++ + E Sbjct: 369 AEAFATGLSEMFRGGQILTQAVLAEFIAEGHFVSHIRRMRGVYAERRETLLEAIRREFGE 428 Query: 251 -FGISGGDSGLHLTLRLPPDCPDTAVSTAARAAGMNVGALSSFSAGPAQAGNNGLVIGYG 309 + G SGLHL L LPP D AV AA A + LS + A+ GL++GYG Sbjct: 429 ALPVHDGASGLHLVLGLPPGTDDVAVVEAALARDVVTRPLSRYYQDDARR-QPGLLLGYG 487 Query: 310 NTSHEQYAALIRRLAGIVR 328 + E LA +R Sbjct: 488 HVETEAIGGRFAVLAEAIR 506 >alr4738 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Nos Nostoc sp. PCC 7120 Length = 490 Score = 238 bits (606), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 135/336 (40%), Positives = 198/336 (58%), Gaps = 12/336 (3%) Query: 2 ALAYGD-PLGEPALREAIAQYLRVARGVRCEAGQVVVTEGSQGALSLCVRLFANPGERAW 60 L Y D LG LREAIA YL +R V C+A Q+++ GSQ L L R+ +P + Sbjct: 158 VLDYTDNSLGYQPLREAIAAYLSRSRAVNCQAEQIIIVGGSQQGLDLITRILIDPNDGIA 217 Query: 61 LEDPGYGGVRAAFHAGDMKIRSMPVDEEGILIAERAWRSPPRL--IHVTPSHQYPTGAVL 118 +E+PGY G R AF A + +PVD+ G+++++ P+L I+VTPSHQ+PTGAVL Sbjct: 218 VEEPGYLGARRAFLAQGASLFPVPVDQSGLIVSKLTTGIIPKLKLIYVTPSHQFPTGAVL 277 Query: 119 SLARRLALIARAREHGCWIIEDDYDSDFRHHGHPIPAMQGLVPDAPVLYVGTFSKTLFPG 178 SL RRL L+A A + G IIEDDYDS++R+ PIPA+QGL V+YVGTFSK LFP Sbjct: 278 SLPRRLELLAWAHKTGVMIIEDDYDSEYRYGERPIPALQGLDQGNSVVYVGTFSKVLFPA 337 Query: 179 LRIGFLVLPSSVGEGAGRALSELLRGGHRLEQLALAEFMAGGQFARHLGRMKRLYRERQQ 238 LR+G+LVLP ++ RA R LEQ AL +F+ G RH+ RM+ LY +R+Q Sbjct: 338 LRLGYLVLPQNLVNIFARAKWLADRQCSLLEQYALTDFITEGHLERHIRRMRSLYNQRRQ 397 Query: 239 ALRAALQAQLPEFG----ISGGDSGLHLTLRLPPDCPDTAVSTAARAAGMNVGALSSFSA 294 L +Q+ FG I G ++G+HL +++ D + +A +G+++GA ++ Sbjct: 398 TL---VQSLFSHFGNRAKILGENAGMHLMVKIDTQISDDEIVQSADLSGVSIGA--AYPQ 452 Query: 295 GPAQAGNNGLVIGYGNTSHEQYAALIRRLAGIVRRV 330 + + + GY + +Q +RRLA ++ + Sbjct: 453 YLKDSPGSEFIFGYAELNEQQIQEGVRRLARVIHNL 488 >BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Bha Bacillus halodurans Length = 469 Score = 225 bits (574), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 118/322 (36%), Positives = 186/322 (57%), Gaps = 3/322 (0%) Query: 3 LAYGDPLGEPALREAIAQYLRVARGVRCEAGQVVVTEGSQGALSLCVRLFANPGERAWLE 62 L YGDP G+ LR+ ++ YL +RGV C QVV+T G+Q A+SL +L + G E Sbjct: 145 LMYGDPFGDWHLRQELSHYLLQSRGVSCRPEQVVITAGTQHAVSLLCQLLSLHGSTVAFE 204 Query: 63 DPGYGGVRAAFHAGDMKIRSMPVDEEGILIAERAWRSPPRLIHVTPSHQYPTGAVLSLAR 122 DPGY GVR+ F +I +P++ +G+ ++ R S +++VTPSHQ P G +L + + Sbjct: 205 DPGYNGVRSVFINQGCRIAPIPIEADGLSLS-RLHESHANIVYVTPSHQLPCGMILPVHK 263 Query: 123 RLALIARAREHGCWIIEDDYDSDFRHHGHPIPAMQGLVPDAPVLYVGTFSKTLFPGLRIG 182 R L+ A EH +I+EDDYDS+FR+ G PIPA++ L + V+Y+GTFSK+ P +R+ Sbjct: 264 RSLLLEWAYEHEGYIVEDDYDSEFRYQGQPIPALKALDQNEKVIYLGTFSKSFLPSIRVS 323 Query: 183 FLVLPSSVGEGAGRALSELLRGGHRLEQLALAEFMAGGQFARHLGRMKRLYRERQQALRA 242 ++VLP + + L+ + +L Q AL F+ G F RH+ RMK++Y+ + L Sbjct: 324 YMVLPGELVPLYQQKLANYNQAASQLIQRALYTFIKDGDFQRHIRRMKKVYQSKHHTLLK 383 Query: 243 ALQAQLPE-FGISGGDSGLHLTLRLPPDCPDTAVSTAARAAGMNVGALSSFSAGPAQAGN 301 +++ L + + G SGLH+ L +P D + A A G+ V + +F P + Sbjct: 384 SVKTYLGDRVTVIGEKSGLHVLLNVPGR-EDHELIEKAMACGVKVYSTKTFWYNPKNQCS 442 Query: 302 NGLVIGYGNTSHEQYAALIRRL 323 + +++G+G S E IRRL Sbjct: 443 SFIMLGFGKLSEEAIKKGIRRL 464