BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0086.p (866 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1028 [J] COG1190 Lysyl-tRNA synthetase (class II) Rso Ralston... 748 0.0 NMA1638 [J] COG1190 Lysyl-tRNA synthetase (class II) NmA Neisser... 627 e-179 NMB1425 [J] COG1190 Lysyl-tRNA synthetase (class II) Nme Neisser... 625 e-179 YPO0888 [J] COG1190 Lysyl-tRNA synthetase (class II) Ype Yersini... 579 e-165 ZlysS [J] COG1190 Lysyl-tRNA synthetase (class II) EcZ Escherich... 575 e-163 >RSc1028 [J] COG1190 Lysyl-tRNA synthetase (class II) Rso Ralstonia solanacearum Length = 510 Score = 748 bits (1932), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/484 (74%), Positives = 407/484 (84%), Gaps = 7/484 (1%) Query: 354 MTTQNTPAAQP--AADENSIIAERRAKLAAIREQGVAFPNDFRPANNAADLHAKYDGLEN 411 MT NTPAA A D+N I+AERR KLAA+R+QGVA+PNDF P ++AADLH +Y + Sbjct: 1 MTEPNTPAAPTGQAQDDNQIMAERREKLAALRQQGVAYPNDFCPTHHAADLHTRYSETDQ 60 Query: 412 EALEAEPVQVTVAGRMMLKRVMGKAAFATLQDASGVRADGRIQLYVTRDVTGEEAMAAFK 471 ALEA V+V +AGRMMLKRVMGKA+FAT+QD SG +IQ Y+TRD GE+ AAFK Sbjct: 61 PALEAANVEVALAGRMMLKRVMGKASFATVQDGSG-----QIQFYITRDRVGEDVYAAFK 115 Query: 472 HYDLGDILGAEGTLFKTKTGELSIKVTKLKLITKSLRPLPDKFHGLADQEMKYRQRYVDL 531 H+DLGDI+ A G LF+T GELS++V +L+L++KSLRPLPDKFHGLADQEMKYRQRYVDL Sbjct: 116 HWDLGDIVAARGVLFRTNKGELSVQVQELRLLSKSLRPLPDKFHGLADQEMKYRQRYVDL 175 Query: 532 IMSEETRRTFKARTAAMSSIRRFMETNGFMEVETPMLHPIPGGAAAKPFITHHNALDMQM 591 I+S ETR TF+ART A++S+R M GFMEVETPMLHPIPGGAAAKPFITHHNALDMQM Sbjct: 176 IVSPETRNTFRARTKAIASLRHHMSDAGFMEVETPMLHPIPGGAAAKPFITHHNALDMQM 235 Query: 592 FMRIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYQWLMGFT 651 F+RIAPELYLKRL+VGGFERV+E+NRNFRNEGVSPRHNPEFTMMEFYAAY DY+WLM +T Sbjct: 236 FLRIAPELYLKRLIVGGFERVYEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDYT 295 Query: 652 EQVIRQAAIDAHGTAVLTYQGRELDLSKPFDRLTITGAILKYAPNYTEAQLADIDFLRTE 711 E +IRQAAIDA G+A L YQGRELDLSKPF RLTI AI KYAP YT+AQLAD +FLR E Sbjct: 296 ENLIRQAAIDATGSAALNYQGRELDLSKPFHRLTICQAIQKYAPQYTDAQLADANFLRAE 355 Query: 712 LKKFGVKTDQAPLAGAGIGALQLALFEETAESQLWNPTYIIDYPVEVSPLARASDTVAGI 771 LKKF + T+ AG+G LQL LFEETAESQLW PT+I+DYPVEVSPLAR SDT+ GI Sbjct: 356 LKKFKIDTNAPQFLNAGVGTLQLVLFEETAESQLWEPTFIVDYPVEVSPLARGSDTLPGI 415 Query: 772 TERFELFITGREIANGFSELNDAEDQAARFQAQVAAKDAGDEEAMYYDADYIRALEYGMP 831 TERFELFITGREIANGFSELND EDQA RF+ QV KDAGDEEAM+YDADYIRALEYGMP Sbjct: 416 TERFELFITGREIANGFSELNDPEDQAERFRKQVEQKDAGDEEAMFYDADYIRALEYGMP 475 Query: 832 PAGG 835 P GG Sbjct: 476 PTGG 479 >NMA1638 [J] COG1190 Lysyl-tRNA synthetase (class II) NmA Neisseria meningitidis Z2491 Length = 503 Score = 627 bits (1617), Expect = e-179, Method: Compositional matrix adjust. Identities = 298/482 (61%), Positives = 374/482 (77%), Gaps = 9/482 (1%) Query: 354 MTTQNTPAAQPAADENSIIAERRAKLAAIREQGVAFPNDFRPANNAADLHAKYDGLENEA 413 M+ QN P +P DEN IIA RR KL IR+Q A+PNDF+ + AADLHA+Y + E Sbjct: 1 MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDSFAADLHAQYGEIGKEE 60 Query: 414 LEAEPVQVTVAGRMMLKRVMGKAAFATLQDASGVRADGRIQLYVTRDVTGEEAMAAFKHY 473 L+ + + V VAGRMMLKR MGKA+FAT+QD SG +IQLY+ +E + F H+ Sbjct: 61 LDPQGIPVKVAGRMMLKRQMGKASFATIQDVSG-----QIQLYLNNKGVSQEVLDDFNHW 115 Query: 474 DLGDILGAEGTLFKTKTGELSIKVTKLKLITKSLRPLPDKFHGLADQEMKYRQRYVDLIM 533 DLGDI+GAEGTLFKT GEL+++V+ ++L++KSLRPLPDK GL+DQE KYRQRYVDLI Sbjct: 116 DLGDIVGAEGTLFKTNHGELTVRVSGIRLLSKSLRPLPDKHKGLSDQETKYRQRYVDLIA 175 Query: 534 SEETRRTFKARTAAMSSIRRFMETNGFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFM 593 +EE+R TF R+ + S+R FM ++EVETPM+HPIPGGA AKPF+THHNALD+ +++ Sbjct: 176 NEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYL 235 Query: 594 RIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYQWLMGFTEQ 653 RIAPELYLKRLVVGG ERVFE+NR+FRNEG+S RHNPEFTM+EFY A+ DY+ +M E Sbjct: 236 RIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAED 295 Query: 654 VIRQAAIDAHGTAVLTYQGRELDLSKPFDRLTITGAILKYAPNYTEAQLADIDFLRTELK 713 +IR A+ +GTA +TY G+E+DL PF+RLTI AI KY P+YT+ QL D ++L+ E+ Sbjct: 296 IIRNASHTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIV 355 Query: 714 KFGVKTDQAPLAGAGIGALQLALFEETAESQLWNPTYIIDYPVEVSPLARASDTVAGITE 773 K G +P GIG+LQLALFE AE +LWNPT+I+DYPVEVSPLARASDT G+TE Sbjct: 356 KHGESLPPSP----GIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTE 411 Query: 774 RFELFITGREIANGFSELNDAEDQAARFQAQVAAKDAGDEEAMYYDADYIRALEYGMPPA 833 RFELF+ GRE+ANG+SELND EDQA RF+AQVA KDAGD+EAM+YDADYIRA+E+G+PP Sbjct: 412 RFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHYDADYIRAMEFGLPPT 471 Query: 834 GG 835 GG Sbjct: 472 GG 473 >NMB1425 [J] COG1190 Lysyl-tRNA synthetase (class II) Nme Neisseria meningitidis MC58 Length = 503 Score = 625 bits (1613), Expect = e-179, Method: Compositional matrix adjust. Identities = 297/482 (61%), Positives = 373/482 (77%), Gaps = 9/482 (1%) Query: 354 MTTQNTPAAQPAADENSIIAERRAKLAAIREQGVAFPNDFRPANNAADLHAKYDGLENEA 413 M+ QN P +P DEN IIA RR KL IR+Q A+PNDF+ + AADLHA+Y + E Sbjct: 1 MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDSFAADLHAQYGEIGKEE 60 Query: 414 LEAEPVQVTVAGRMMLKRVMGKAAFATLQDASGVRADGRIQLYVTRDVTGEEAMAAFKHY 473 L+ + + V VAGRMMLKR MGKA+FAT+QD SG +IQLY+ +E + F H+ Sbjct: 61 LDPQGIPVKVAGRMMLKRQMGKASFATIQDVSG-----QIQLYLNNKGVSQEVLDDFNHW 115 Query: 474 DLGDILGAEGTLFKTKTGELSIKVTKLKLITKSLRPLPDKFHGLADQEMKYRQRYVDLIM 533 DLGDI+GAEGTLFKT GEL+++V+ ++L++KSLRPLPDK GL+DQE KYRQRYVDLI Sbjct: 116 DLGDIVGAEGTLFKTNHGELTVRVSGIRLLSKSLRPLPDKHKGLSDQETKYRQRYVDLIA 175 Query: 534 SEETRRTFKARTAAMSSIRRFMETNGFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFM 593 +EE+R TF R+ + S+R FM ++EVETPM+HPIPGGA AKPF+THHNALD+ +++ Sbjct: 176 NEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYL 235 Query: 594 RIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYQWLMGFTEQ 653 RIAPELYLKRLVVGG ERVFE+NR+FRNEG+S RHNPEFTM+EFY A+ DY+ +M E Sbjct: 236 RIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAED 295 Query: 654 VIRQAAIDAHGTAVLTYQGRELDLSKPFDRLTITGAILKYAPNYTEAQLADIDFLRTELK 713 +IR A+ +GTA +TY G+E+DL PF+RLTI AI KY P+YT+ QL D ++L+ E+ Sbjct: 296 IIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIV 355 Query: 714 KFGVKTDQAPLAGAGIGALQLALFEETAESQLWNPTYIIDYPVEVSPLARASDTVAGITE 773 K G +P GIG+LQLALFE AE +LWNPT+I+DYPVEVSPLARASDT G+TE Sbjct: 356 KHGESLPPSP----GIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTE 411 Query: 774 RFELFITGREIANGFSELNDAEDQAARFQAQVAAKDAGDEEAMYYDADYIRALEYGMPPA 833 RFELF+ GRE+ANG+SELND EDQA RF+AQV KDAGD+EAM+YDADYIRA+E+G+PP Sbjct: 412 RFELFVVGRELANGYSELNDPEDQAERFKAQVVQKDAGDDEAMHYDADYIRAMEFGLPPT 471 Query: 834 GG 835 GG Sbjct: 472 GG 473 >YPO0888 [J] COG1190 Lysyl-tRNA synthetase (class II) Ype Yersinia pestis Length = 505 Score = 579 bits (1493), Expect = e-165, Method: Compositional matrix adjust. Identities = 290/487 (59%), Positives = 354/487 (72%), Gaps = 18/487 (3%) Query: 354 MTTQNTPAAQPAADENSIIAERRAKLAAIREQGVAFPNDFRPANNAADLHAKYDGLENEA 413 M+ Q A+ A + NS + RR KLA +R +G+AFPNDFR N + LHA++D ENE Sbjct: 1 MSEQKPQVAEQAQELNSELQARREKLAVLRGKGIAFPNDFRRENLSDQLHAEFDSKENEE 60 Query: 414 LEAEPVQVTVAGRMMLKRVMGKAAFATLQDASGVRADGRIQLYVTRD-----VTGEEAMA 468 LEA + VTVAGRMM +R+MGKA+F TLQD G RIQLYV+RD V EE Sbjct: 61 LEALNIDVTVAGRMMTRRIMGKASFVTLQDVGG-----RIQLYVSRDDLPEGVYNEE--- 112 Query: 469 AFKHYDLGDILGAEGTLFKTKTGELSIKVTKLKLITKSLRPLPDKFHGLADQEMKYRQRY 528 FK +DLGDILGA G LFKTKTGELSI ++L+L+TK+LRPLPDKFHGLADQE +YRQRY Sbjct: 113 -FKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGLADQETRYRQRY 171 Query: 529 VDLIMSEETRRTFKARTAAMSSIRRFMETNGFMEVETPMLHPIPGGAAAKPFITHHNALD 588 +DLI ++E+R TFK R+ MS IR FM GFMEVETPM+ IPGGA+A+PF+THHNALD Sbjct: 172 LDLIANDESRHTFKVRSQVMSGIRSFMVEKGFMEVETPMMQVIPGGASARPFVTHHNALD 231 Query: 589 MQMFMRIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYQWLM 648 + M++RIAPELYLKRLVVGGFERVFE+NRNFRNEGVSPRHNPEFTMME Y AY DY+ L+ Sbjct: 232 IDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLI 291 Query: 649 GFTEQVIRQAAIDAHGTAVLTYQGRELDLSKPFDRLTITGAILKYAPNYTEAQLADIDFL 708 TE++ R G++V+ Y + D KPF +LT+ AI KY P A L D+D Sbjct: 292 VLTEELFRTLTETILGSSVVQYGEQTFDFGKPFAKLTMKEAICKYRPETNVADLDDMDKA 351 Query: 709 RTELKKFGVKTDQAPLAGAGIGALQLALFEETAESQLWNPTYIIDYPVEVSPLARASDTV 768 + G+K +++ G+G +Q +FEETAES L PT+I +YP EVSPLAR +D Sbjct: 352 VAIAESLGIKVEKS----WGLGRIQCEIFEETAESHLIQPTFITEYPAEVSPLARRNDDN 407 Query: 769 AGITERFELFITGREIANGFSELNDAEDQAARFQAQVAAKDAGDEEAMYYDADYIRALEY 828 IT+RFE FI GREI NGFSELNDAEDQA RF QV+AK+AGD+EAM+YD DYI ALE+ Sbjct: 408 PFITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQVSAKEAGDDEAMFYDEDYITALEH 467 Query: 829 GMPPAGG 835 G+PP G Sbjct: 468 GLPPTAG 474 >ZlysS [J] COG1190 Lysyl-tRNA synthetase (class II) EcZ Escherichia coli O157:H7 EDL933 Length = 505 Score = 575 bits (1482), Expect = e-163, Method: Compositional matrix adjust. Identities = 286/483 (59%), Positives = 350/483 (72%), Gaps = 10/483 (2%) Query: 354 MTTQNTPAAQPAADENSIIAERRAKLAAIREQGVAFPNDFRPANNAADLHAKYDGLENEA 413 M+ Q+ A D N+ + RR KLA +REQG+AFPNDFR + + LHA++DG ENE Sbjct: 1 MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEE 60 Query: 414 LEAEPVQVTVAGRMMLKRVMGKAAFATLQDASGVRADGRIQLYVTRDVTGEEAM-AAFKH 472 LEA ++V VAGRMM +R+MGKA+F TLQD G RIQLYV RD E FK Sbjct: 61 LEALNIEVAVAGRMMTRRIMGKASFVTLQDVGG-----RIQLYVARDDLPEGVYNEQFKK 115 Query: 473 YDLGDILGAEGTLFKTKTGELSIKVTKLKLITKSLRPLPDKFHGLADQEMKYRQRYVDLI 532 +DLGDILGA+G LFKTKTGELSI T+L+L+TK+LRPLPDKFHGL DQE +YRQRY+DLI Sbjct: 116 WDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLI 175 Query: 533 MSEETRRTFKARTAAMSSIRRFMETNGFMEVETPMLHPIPGGAAAKPFITHHNALDMQMF 592 ++E+R TFK R+ +S IR+FM GFMEVETPM+ IPGGAAA+PFITHHNALD+ M+ Sbjct: 176 SNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMY 235 Query: 593 MRIAPELYLKRLVVGGFERVFEVNRNFRNEGVSPRHNPEFTMMEFYAAYVDYQWLMGFTE 652 +RIAPELYLKRLVVGGFERVFE+NRNFRNEG+S RHNPEFTMME Y AY DY+ L+ TE Sbjct: 236 LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTE 295 Query: 653 QVIRQAAIDAHGTAVLTYQGRELDLSKPFDRLTITGAILKYAPNYTEAQLADIDFLRTEL 712 + R A D G +TY LD KPF++LT+ AI KY P A L + D + + Sbjct: 296 SLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIV 355 Query: 713 KKFGVKTDQAPLAGAGIGALQLALFEETAESQLWNPTYIIDYPVEVSPLARASDTVAGIT 772 + G+ +++ G+G + +FEE AE+ L PT+I +YP EVSPLAR +D IT Sbjct: 356 ESIGIHVEKS----WGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEIT 411 Query: 773 ERFELFITGREIANGFSELNDAEDQAARFQAQVAAKDAGDEEAMYYDADYIRALEYGMPP 832 +RFE FI GREI NGFSELNDAEDQA RF QVAAKDAGD+EAM+YD DY+ ALE+G+PP Sbjct: 412 DRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPP 471 Query: 833 AGG 835 G Sbjct: 472 TAG 474