BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0056.p (423 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1177 [GEPR] COG0477 Permeases of the major facilitator superf... 426 e-119 PA4622 [GEPR] COG0477 Permeases of the major facilitator superfa... 413 e-115 CAP0049 [GEPR] COG0477 Permeases of the major facilitator superf... 411 e-114 mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf... 337 4e-92 SMc03237 [GEPR] COG0477 Permeases of the major facilitator super... 335 1e-91 >RSp1177 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 426 bits (1095), Expect = e-119, Method: Compositional matrix adjust. Identities = 250/414 (60%), Positives = 310/414 (74%), Gaps = 13/414 (3%) Query: 10 PDEAAESLRH----HTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQ 65 P A++L H + F+LFW A +++T A QM VAVGWQ+Y LT SA+ LG+VGL Q Sbjct: 10 PPAPAQTLSHAPFAYPAFRLFWLARLSTTFAYQMFGVAVGWQIYDLTRSAYVLGLVGLAQ 69 Query: 66 FIPSLILVFVVGHVADRFDRRNVARVSSLVEAAAAATLALGSLHGWLSREMIFVIVAIIG 125 F+PS++LV GH+ADR+DRR V R+ +EA AA LA +L G S + IFV V +IG Sbjct: 70 FLPSVVLVLASGHIADRYDRRRVVRICQAIEALVAAMLAAATLTGHASIQPIFVFVVVIG 129 Query: 126 AGRAFSKPTMSALLPSLMSPKALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASS 185 A RAF PT+ ALLPSL+ P ALP AVA S+SA Q II+GPA+GGFLYVAG VVYA++ Sbjct: 130 AMRAFETPTLQALLPSLVPPAALPRAVALSSSAGQTGIILGPAVGGFLYVAGAPVVYATA 189 Query: 186 CALFIACSVLLSLIRRPAQVTAAQAAP-AKPTGASLSSVFAGLAFIRSKPAIFGAISLDM 244 LF+ VL++ +R +AAP ++P SL S+FAG+AFI+ +P + GAISLD+ Sbjct: 190 AGLFVLAHVLVACVR------TGRAAPVSRPV--SLESLFAGIAFIKGRPVVLGAISLDL 241 Query: 245 FAVLLGGATALLPVFANDILHTGAVGLGLLRSAPAAGALIVALLLARFPLGGRVGRTMFI 304 FAVLLGGATALLP++A DIL TGA GLGLLRSAPA GAL +A+ LA PL VGR MF Sbjct: 242 FAVLLGGATALLPIYARDILGTGAWGLGLLRSAPAIGALAMAIFLAHRPLERHVGRVMFA 301 Query: 305 AVAVFGLATIVFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNS 364 AVA+FGLAT+VFG+SR PLS+ AL VLGA DM+SVV+R+S VQL+TPDAMRGRVSAVNS Sbjct: 302 AVALFGLATMVFGVSRWLPLSMLALVVLGAGDMVSVVIRTSLVQLDTPDAMRGRVSAVNS 361 Query: 365 VFIGTSNQLGEFESGLTAAWFGAVPAVLIGGIGTLLIVLLWMRLFPSLYQVDRL 418 VF+G SNQLGEFESG+ A G VP+V++GG+GTLL+V LWMRLFP+L DRL Sbjct: 362 VFVGASNQLGEFESGMVAGMLGPVPSVVLGGLGTLLVVALWMRLFPALTHRDRL 415 >PA4622 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 413 bits (1061), Expect = e-115, Method: Compositional matrix adjust. Identities = 232/405 (57%), Positives = 283/405 (69%), Gaps = 9/405 (2%) Query: 15 ESLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVF 74 SL H PF FW A V + QM VA+GW +Y+LT + DLG+VGLV+F+P ++ + Sbjct: 6 SSLLRHRPFLAFWLARVCTASGFQMLTVAIGWHIYELTGNVLDLGLVGLVEFLPRVLFML 65 Query: 75 VVGHVADRFDRRNVARVSSLVEAAAAATLALGSLHGWLSREMIFVIVAIIGAGRAFSKPT 134 GHVADR+DRR +A + +A A L LG+ G ++R MIFV+ +G RAF PT Sbjct: 66 HTGHVADRYDRRRIAALCQAGQALVAVALVLGAASGEITRNMIFVLAFALGTARAFEMPT 125 Query: 135 MSALLPSLMSPKALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFI-ACS 193 ALLP+L+ P AVA SASA Q A I PALGG LY G + VY + L++ AC Sbjct: 126 TQALLPNLVPAGLFPRAVAASASAMQAATIAAPALGGLLYAFGASWVYVPTATLYVLACV 185 Query: 194 VLLSLIRRPAQVTAAQAAPAKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGAT 253 + LSL R +T +A +L S+ AG+ FIRS+P IFGAISLD+FAVLLGGAT Sbjct: 186 LTLSLPVRNQPLTQGKA--------TLDSLLAGIRFIRSRPDIFGAISLDLFAVLLGGAT 237 Query: 254 ALLPVFANDILHTGAVGLGLLRSAPAAGALIVALLLARFPLGGRVGRTMFIAVAVFGLAT 313 ALLPVFA DIL TG GLGLLRSAPA GAL ++ LA F + VGR MF++V +FGLAT Sbjct: 238 ALLPVFAKDILLTGPWGLGLLRSAPAVGALAMSFWLAHFSIERNVGRIMFLSVGIFGLAT 297 Query: 314 IVFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQL 373 I FGLS+SF LSL L VLGAADM+S+V+R +FVQLETPD MRGRVSAVN +FIG SNQL Sbjct: 298 IAFGLSKSFWLSLGVLVVLGAADMVSMVIRGAFVQLETPDEMRGRVSAVNGLFIGASNQL 357 Query: 374 GEFESGLTAAWFGAVPAVLIGGIGTLLIVLLWMRLFPSLYQVDRL 418 GEFESGLTA WFG VPAV++GGIGTL++ WM+LFPSL Q DRL Sbjct: 358 GEFESGLTAHWFGTVPAVVLGGIGTLVVTGAWMKLFPSLAQRDRL 402 >CAP0049 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 408 Score = 411 bits (1057), Expect = e-114, Method: Compositional matrix adjust. Identities = 207/396 (52%), Positives = 277/396 (69%), Gaps = 7/396 (1%) Query: 28 CASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVFVVGHVADRFDRRN 87 A V+S A QM VA+GWQ+Y LTHSAF LG++GLVQF+P L+L VGH++DR+DRR Sbjct: 20 TARVSSNFAYQMLTVAIGWQMYSLTHSAFYLGLIGLVQFLPMLVLSLFVGHISDRYDRRK 79 Query: 88 VARVSSLVEAAAAATLALGSLHGWLSREMIFVIVAIIGAGRAFSKPTMSALLPSLMSPKA 147 + +S LV+ A LA G+ +GW+++E ++V I +F P M ALLP+++ K Sbjct: 80 IVSISQLVQGICIALLAFGNYNGWITKESFLIMVFFIALAHSFEGPPMQALLPNIVERKI 139 Query: 148 LPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFIACSVLLSLIRRPAQVTA 207 P A A +SA+QFA+I+GP G LY G +++Y+ + L I SVL+ I Sbjct: 140 FPKASALVSSASQFAVIVGPGFAGILYSFGASLIYSITAGLLILASVLIIQIH------- 192 Query: 208 AQAAPAKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATALLPVFANDILHTG 267 KP +L S FAG+ FI+S+P I GAISLD+FAVL GGATALLP++A+ IL G Sbjct: 193 VNKEERKPDPVNLKSFFAGITFIKSRPIILGAISLDLFAVLFGGATALLPIYASSILKIG 252 Query: 268 AVGLGLLRSAPAAGALIVALLLARFPLGGRVGRTMFIAVAVFGLATIVFGLSRSFPLSLA 327 + GLG+LRSAPA GAL+++ LL R PL VG+ MF AV FGL+TI+F +S+S +S Sbjct: 253 SFGLGVLRSAPAVGALLMSALLTRKPLKRNVGKIMFTAVVCFGLSTIIFAISKSVIVSFL 312 Query: 328 ALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLGEFESGLTAAWFGA 387 AL VLGA+D+ISVV+RS+ VQLETPD MRGRVS+VN +FIGTSNQLGEFESG+TA+ G Sbjct: 313 ALFVLGASDVISVVIRSTLVQLETPDNMRGRVSSVNMIFIGTSNQLGEFESGITASLLGT 372 Query: 388 VPAVLIGGIGTLLIVLLWMRLFPSLYQVDRLAARQS 423 VPA L+GG+GT+L+VL+W +LF SL+ VD ++ Sbjct: 373 VPAALLGGVGTILVVLIWRKLFSSLFTVDSFEGSKN 408 >mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 412 Score = 337 bits (863), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 195/413 (47%), Positives = 259/413 (62%), Gaps = 8/413 (1%) Query: 10 PDEAAESLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPS 69 P++ + RH F +W A +T A + VAVGWQ+Y LT FDLGIVG+VQF+PS Sbjct: 8 PEQRYAAFRHKA-FLSYWTARFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGIVQFLPS 66 Query: 70 LILVFVVGHVADRFDRRNVARVSSLVEAAAAATLALGSLHGWLSREMIFVIVAIIGAGRA 129 L+LV V G VADRF RR + ++ +VEA A L +L IF ++A+ G RA Sbjct: 67 LLLVLVTGAVADRFGRRLIMALAVVVEAICALALLALTLRSISGPLPIFCVLAMFGVARA 126 Query: 130 FSKPTMSALLPSLMSPKALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALF 189 F P ++L +L+ P+ A+A ++SA Q A I+GP GG LY P V Y ++ L Sbjct: 127 FFGPASASLFANLVPPEDFANAIAWNSSAWQTATIVGPVAGGLLYGVSPEVAYGTAAVLM 186 Query: 190 IACSVLLSLIRRPAQVTAAQAAPAKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLL 249 +A +L+ I +PAQ T + KPT L ++F G ++I S+ + GAISLD+FAVLL Sbjct: 187 LASGLLIFTIPKPAQRTETE----KPT---LQNLFGGFSYIWSEKIVLGAISLDLFAVLL 239 Query: 250 GGATALLPVFANDILHTGAVGLGLLRSAPAAGALIVALLLARFPLGGRVGRTMFIAVAVF 309 GA+ALLPV+A DIL G GLGLLRSAP+ GA+ VA+ LA P+ G M A A F Sbjct: 240 SGASALLPVYARDILQLGPWGLGLLRSAPSIGAICVAVWLAGHPMRNHAGMIMLAAAASF 299 Query: 310 GLATIVFGLSRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGT 369 G T++FGLS LS+AAL LGA DM SV +R + +QL TPD +RGRV+AVN VF+G Sbjct: 300 GAFTVLFGLSTITWLSIAALVFLGATDMFSVYIRETLIQLWTPDEVRGRVNAVNQVFVGA 359 Query: 370 SNQLGEFESGLTAAWFGAVPAVLIGGIGTLLIVLLWMRLFPSLYQVDRLAARQ 422 SN++GEF +G AA G VPAV+IGG+G + + LWM LFP L +V L R Sbjct: 360 SNEVGEFRAGTMAALIGTVPAVVIGGVGAIAVAGLWMVLFPQLRKVRHLNGRN 412 >SMc03237 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 415 Score = 335 bits (858), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 183/400 (45%), Positives = 264/400 (66%), Gaps = 7/400 (1%) Query: 19 HHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAFDLGIVGLVQFIPSLILVFVVGH 78 H ++ ++ + + + A+Q+ VAVGWQ+Y LT F LG++GL QF+PSL+L+ V G Sbjct: 14 RHVGYRRYFFSRLLAYFAVQIMSVAVGWQIYDLTRDPFSLGLIGLFQFLPSLVLILVTGS 73 Query: 79 VADRFDRRNVARVSSLVEAAAAATLALGSLHGWLSREMIFVIVAIIGAGRAFSKPTMSAL 138 VADR++RR + + LV A L L ++ G S ++ I+ + G RAF P +L Sbjct: 74 VADRYNRRAIMGICMLVSTLCGAALLLLTVTGLFSPWPVYAILVVFGIERAFLGPASQSL 133 Query: 139 LPSLMSPKALPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCALFIACSVLLSL 198 P+L+ + LP A+A ++++ Q A+I+GP GG LY GP V YA S F A ++++ Sbjct: 134 APNLVPAEDLPNAIAWNSTSWQTAMIVGPVAGGLLYGFGPTVPYAVSLGFFAAGALMVFA 193 Query: 199 IRRPAQVTAAQAAPAKPTGASLSSVFAGLAFIRSKPAIFGAISLDMFAVLLGGATALLPV 258 + +PA+ + P+ A+ ++ AG +I+++ + GAISLD+FAVLLGGA AL+PV Sbjct: 194 VPKPARRS-------PPSAANWQTITAGFRYIKAEKIVLGAISLDLFAVLLGGAVALMPV 246 Query: 259 FANDILHTGAVGLGLLRSAPAAGALIVALLLARFPLGGRVGRTMFIAVAVFGLATIVFGL 318 FA D+L G GLGLLR+AP GA+ +A+ LA P+ R G MF+ VA+FGLAT+VFGL Sbjct: 247 FARDVLTLGPWGLGLLRAAPGVGAVGMAVWLAAHPIRNRAGLYMFVGVALFGLATVVFGL 306 Query: 319 SRSFPLSLAALAVLGAADMISVVVRSSFVQLETPDAMRGRVSAVNSVFIGTSNQLGEFES 378 S + +S+AAL V+GA+DMISV VR + L TPD +RGRV+AVN VF+G SN+LGEF + Sbjct: 307 SATPWISIAALVVMGASDMISVYVREILITLWTPDELRGRVNAVNMVFVGASNELGEFRA 366 Query: 379 GLTAAWFGAVPAVLIGGIGTLLIVLLWMRLFPSLYQVDRL 418 G+ A+ FG V AV+ GG GTLL+ LLW FP L ++D L Sbjct: 367 GMMASGFGTVFAVVFGGAGTLLVSLLWALGFPQLRRIDTL 406