BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0197.p (1168 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4112_3 [T] COG0642 Signal transduction histidine kinase Pae Ps... 244 8e-64 VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vi... 215 5e-55 PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Ps... 213 3e-54 mll3725_2 [T] COG0642 Signal transduction histidine kinase Mlo M... 211 7e-54 MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Me... 209 2e-53 >PA4112_3 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 242 Score = 244 bits (623), Expect = 8e-64, Method: Compositional matrix adjust. Identities = 131/243 (53%), Positives = 170/243 (69%), Gaps = 9/243 (3%) Query: 548 FLASVSHEIRTPMNGVLGMIQLLQRTQPQPAQRDYLNKAEISESLXPEISAKSLLNLLND 607 FLA++SHEIRTPMN VLGM+QL ++T QRDYL+KA + A SLL LLND Sbjct: 1 FLANMSHEIRTPMNAVLGMLQLARQTDLNERQRDYLDKASSA--------ATSLLGLLND 52 Query: 608 LLDFSKMDAQQVQLDLQAFSLEHFRHDLTAILAGNPPQEGVSLHIELDGDLPQRVVGDVY 667 +LD+SK++A ++ L++ F LE DL +L+GN + V + ++D +LP VVGD Sbjct: 53 ILDYSKIEAGKLVLEMLPFELEPLMQDLAVVLSGNQGDKDVEVIFDIDPELPSAVVGDRL 112 Query: 668 RLQQVLVNLISNALKFTHLGRIDVALRRLAADNTRQVMLRVEVSDTGIGIAPERLKDIFD 727 RLQQ+L+NL NALKFT G + V+LRRLA D V LRV V+DTGIGI+ E+ + IF+ Sbjct: 113 RLQQILINLAGNALKFTARGHVLVSLRRLAHD-AHLVRLRVLVADTGIGISAEQQQRIFE 171 Query: 728 AFTQAEASTTRRYGGTGLGLAISRHLVQLMGGQLQVSSEPGRGSRFWFDLPMEIEDATPL 787 FTQAEAST+RR+GGTGLGL I + LV LMGG+L+V S PG GSRFWFDL +++ PL Sbjct: 172 GFTQAEASTSRRFGGTGLGLFICKRLVDLMGGELRVESAPGSGSRFWFDLDLDVAHDQPL 231 Query: 788 SQA 790 A Sbjct: 232 RAA 234 >VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 260 Score = 215 bits (548), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 117/256 (45%), Positives = 172/256 (67%), Gaps = 9/256 (3%) Query: 529 NNLVEARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPQPAQRDYLNKAEI 588 + L +A+ A+ + AK FLA++SHEIRTPMN +LGM L T QR Y+ + I Sbjct: 1 DELRKAKEAADAMSQAKGDFLANMSHEIRTPMNAILGMAHLALNTPLDTTQRKYVTR--I 58 Query: 589 SESLXPEISAKSLLNLLNDLLDFSKMDAQQVQLDLQAFSLEHFRHDLTAILAGNPPQEGV 648 +ES AK+LL ++ND+LDFSKM+A ++ ++ F+L+ ++TA+++ ++G+ Sbjct: 59 NES------AKNLLGIINDILDFSKMEAGKLNVERIDFNLDDVLDNVTAVVSLKAQEKGI 112 Query: 649 SLHIELDGDLPQRVVGDVYRLQQVLVNLISNALKFTHLGRIDVALRRLAADNTRQVMLRV 708 +++D +P ++GD RL QV+VNL NA+KFT G I V R++ N +QV LR Sbjct: 113 EFLMDIDPHIPLGLIGDPLRLGQVMVNLCGNAVKFTSQGEI-VLSARVSQLNEQQVTLRF 171 Query: 709 EVSDTGIGIAPERLKDIFDAFTQAEASTTRRYGGTGLGLAISRHLVQLMGGQLQVSSEPG 768 V DTGIGIA ++L D+FDAF+QA+ S TR+YGGTGLGL+IS+ LV+LMGGQ+ V SE G Sbjct: 172 AVKDTGIGIAQDKLDDLFDAFSQADNSITRQYGGTGLGLSISKQLVELMGGQITVHSEEG 231 Query: 769 RGSRFWFDLPMEIEDA 784 +GS F F + ++DA Sbjct: 232 KGSTFEFSVVCGLQDA 247 >PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 385 Score = 213 bits (541), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 125/279 (44%), Positives = 184/279 (65%), Gaps = 18/279 (6%) Query: 544 AKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPQPAQRDYLNKAEISESLXPEISAKSLLN 603 AKS FLA +SHEIRTP+NGVLGM+QLL+ T Q Y+ S S +L++ Sbjct: 1 AKSRFLAKMSHEIRTPLNGVLGMLQLLRDTPLDRGQAAYVETIASSGS--------ALMS 52 Query: 604 LLNDLLDFSKMDAQQVQLDLQAFSLEHFRHDLTAILAGNPPQEGVSLHIELDGDLPQRVV 663 ++ND+LD++++++ ++ L+ F LE D A+ + ++ + LH+ LD +P+R+ Sbjct: 53 VINDILDYARIESGKLHLERIDFDLEELLSDTLALFSAQAVEKRLHLHLGLDRGVPRRLN 112 Query: 664 GDVYRLQQVLVNLISNALKFTHLGRIDVALRRLAADNTRQVMLRVEVSDTGIGIAPERLK 723 GD RL+QVL+NL+SNALKFT G + V ++R + R+ +L VSD+GIGI+ + K Sbjct: 113 GDPTRLRQVLMNLLSNALKFTAEGHVAVRVQRRFDEGGRERLL-YSVSDSGIGISAQAQK 171 Query: 724 DIFDAFTQAEASTTRRYGGTGLGLAISRHLVQLMGGQLQVSSEPGRGSRFWFDLPMEIED 783 +F++F+QA++STTRRYGG+GLGLAISR LVQ+MGG+++VSSEPG+G+RF DLP+ Sbjct: 172 TLFESFSQADSSTTRRYGGSGLGLAISRELVQMMGGRIEVSSEPGKGTRFSVDLPL---- 227 Query: 784 ATPLSQARAADEHTQ-AEHAP---AGETARELEGVQILL 818 +P A ADE Q +H P A E L+ +Q LL Sbjct: 228 -SPALDAGEADELAQLLQHRPALLASEDNLTLDCLQALL 265 >mll3725_2 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 328 Score = 211 bits (537), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 129/307 (42%), Positives = 187/307 (60%), Gaps = 20/307 (6%) Query: 478 TGEFEPVFRVVR-ADGSIR--FVQARAHVDRNGMGAPVRVIGINLDITQRIEFENNLVEA 534 TGE + V VR ADGS+R F + A + +G + +IG DIT+ E L EA Sbjct: 19 TGETQEVEETVRLADGSVRHQFARKGAMIASDG---SLYLIGSTTDITELKMREAELSEA 75 Query: 535 RLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPQPAQRDYLNKAEISESLXP 594 R +A A+ AKS FLA++SHEIRTPMNGVLGM +LL ++ P Q+ + + Sbjct: 76 RQRAVLADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTD--------II 127 Query: 595 EISAKSLLNLLNDLLDFSKMDAQQVQLDLQAFSLEHFRHDLTAILAGNPPQEGVSLHIEL 654 S +LL ++ND+LDFSK+DA Q+ LD F+L D+ +++ ++ + L + + Sbjct: 128 VKSGNALLTIINDILDFSKIDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRV 187 Query: 655 DGDLPQRVVGDVYRLQQVLVNLISNALKFTHLGRI--DVALRRLAADNTRQVMLRVEVSD 712 + L VGDV R++Q++ NL+ NA+KFT G + DV R+ TR L + V+D Sbjct: 188 EPRLESLFVGDVGRIRQIVTNLLGNAVKFTDEGHVLVDVTGERVPT-GTR---LTISVTD 243 Query: 713 TGIGIAPERLKDIFDAFTQAEASTTRRYGGTGLGLAISRHLVQLMGGQLQVSSEPGRGSR 772 TGIGI E+LK +F+ F+Q + S+TRR+ GTGLGLAI+ LV+LMGG + V S G+GS Sbjct: 244 TGIGIPEEKLKLVFEKFSQVDTSSTRRHEGTGLGLAITSRLVELMGGTIGVESAEGKGST 303 Query: 773 FWFDLPM 779 FWF + + Sbjct: 304 FWFTVTL 310 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Methanosarcina acetivorans str.C2A Length = 296 Score = 209 bits (533), Expect = 2e-53, Method: Composition-based stats. Identities = 115/258 (44%), Positives = 162/258 (62%), Gaps = 18/258 (6%) Query: 528 ENNLVEARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPQPAQRDYLNKAE 587 E L++A+ AE AN AK FLA++SHEIRTPMN VLGM+++L T QR+YL A Sbjct: 4 EEQLLKAKEAAESANKAKGDFLANMSHEIRTPMNAVLGMLEMLLETSLTDEQREYLQLAH 63 Query: 588 ISESLXPEISAKSLLNLLNDLLDFSKMDAQQVQLDLQAFSLEHFRHDLTAILAGNPPQEG 647 S A+SLL++++D+LDFSK++ +++L+ +F LE + +L+G +G Sbjct: 64 AS--------AESLLSIIDDVLDFSKIEQNKLELEQISFELESLISHIINLLSGKAGSKG 115 Query: 648 VSLHIELDGDLPQRVVGDVYRLQQVLVNLISNALKFTHLGRIDVALRRLA---------- 697 + L ++ DLP +GD RL+QVL N++ NA+KFT G I +++ Sbjct: 116 LKLAFHIEKDLPSTFIGDPVRLKQVLFNILGNAIKFTKKGEIALSVEVYMPSERNSGLSN 175 Query: 698 ADNTRQVMLRVEVSDTGIGIAPERLKDIFDAFTQAEASTTRRYGGTGLGLAISRHLVQLM 757 +D +V L +V DTGIGI PE+L IFD F QA+AS TR YGGTGLGLAIS LV+LM Sbjct: 176 SDFPEEVALLFKVKDTGIGIPPEKLSQIFDPFIQADASVTREYGGTGLGLAISSQLVELM 235 Query: 758 GGQLQVSSEPGRGSRFWF 775 G++ V SE G+G F+F Sbjct: 236 EGRIWVESEVGKGCTFYF 253