BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0181.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5370 [GEPR] COG0477 Permeases of the major facilitator superfa... 496 e-140 YPO0465 [GEPR] COG0477 Permeases of the major facilitator superf... 463 e-130 BMEI0353 [GEPR] COG0477 Permeases of the major facilitator super... 423 e-118 AGc3904 [GEPR] COG0477 Permeases of the major facilitator superf... 421 e-117 Cj0250c [GEPR] COG0477 Permeases of the major facilitator superf... 348 2e-95 >PA5370 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 438 Score = 496 bits (1276), Expect = e-140, Method: Compositional matrix adjust. Identities = 248/417 (59%), Positives = 311/417 (74%), Gaps = 8/417 (1%) Query: 36 HRPLTSSDYRTLGLSALGGTLEFYDFVIYVFFAAVVGKLFFPADMPEWLRMLQTFGIFAA 95 RPLT SDY+TL LSALGG LEFYDF+I+VFFA VVGKLFFPADMPEWLR LQTFG+FAA Sbjct: 12 QRPLTRSDYKTLSLSALGGALEFYDFIIFVFFATVVGKLFFPADMPEWLRQLQTFGLFAA 71 Query: 96 GYLARPVGGIIIAHYGDVIGRKRMFTLSIFLMAVPTLVIGLLPTYASIGVAAPILLLLMR 155 GYLARP+GG+I+AH+GD++GRKRMFTLSIF+MAVPTL++GLLPTYA IG+ AP+ LLL+R Sbjct: 72 GYLARPLGGVIMAHFGDLLGRKRMFTLSIFMMAVPTLIMGLLPTYAQIGIWAPLALLLLR 131 Query: 156 TLQGAAIGGEMPGAWVFVAEHVPANRYSFGVGSLTAGITGGILLGSLMGIFINSVYAPAE 215 +QGAAIGGE+PGAWVFVAEHVPA + G+LT+G+T GILLGSL+ INS Y+ E Sbjct: 132 VIQGAAIGGEVPGAWVFVAEHVPARHVGYACGTLTSGLTAGILLGSLVATAINSFYSATE 191 Query: 216 VAGYAWRIPFILGGVFGLVSVYLRRYLEETPVGKK--------XELPLKTVLREHRAASV 267 V YAWRIPF+LGGVFGL SVYLRR+L ETPV + E+PLK V+R+HR A + Sbjct: 192 VQDYAWRIPFLLGGVFGLFSVYLRRWLHETPVFAELQQRKALAEEVPLKAVVRDHRGAVL 251 Query: 268 LTAGMTWCLSGAVVVVILMTPSYLQTVHHLPAKLVMQANCAGTLMLTIGCLAIGWLCDRI 327 ++ +TW LS A+VVVILMTP+ LQ+V+ A ++AN + LT+GC+ G + DR Sbjct: 252 VSMLLTWVLSAAIVVVILMTPTVLQSVYGFDAATALKANSLAIVCLTLGCIVAGRMADRY 311 Query: 328 GTRASMIIGWGGLGLSTWWFYGQLPGSPESLIWGYALVGLFVGSISLTPIVSTRAFPPPV 387 G + + G L L +W FYG L P+ L YAL G FVG + P V AFPP V Sbjct: 312 GAGLTFVAGSVLLALVSWSFYGNLKAHPDWLFPLYALTGFFVGIVGAVPYVMVNAFPPVV 371 Query: 388 RFTGLSFAYNMAYAVFGGLTPVLISLWIKADPQGPALYVIGLSILGVLLAFVPMSSK 444 RF+GLSF+YN+AYA+FGGLTP+ ++L +K P GPA YV+ L ++G L+ ++ K Sbjct: 372 RFSGLSFSYNLAYAIFGGLTPMAVALLLKQSPMGPAYYVVTLCLVGFLVGLYLLAQK 428 >YPO0465 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 462 Score = 463 bits (1191), Expect = e-130, Method: Compositional matrix adjust. Identities = 230/416 (55%), Positives = 297/416 (71%), Gaps = 8/416 (1%) Query: 19 TTSAESAEFTGALNESQHRPLTSSDYRTLGLSALGGTLEFYDFVIYVFFAAVVGKLFFPA 78 ++ +S++ + +R L DY+TL L+ALGG LEFYDF+I+VFFAAV+G LFFPA Sbjct: 12 SSQIDSSQHHVDQQHNHNRRLNKQDYKTLTLAALGGALEFYDFIIFVFFAAVIGDLFFPA 71 Query: 79 DMPEWLRMLQTFGIFAAGYLARPVGGIIIAHYGDVIGRKRMFTLSIFLMAVPTLVIGLLP 138 DMPEWLR +QTFGIFAAGYLARP+GGII+AH+GD++GRK+MFTLSI LMA+PTL IG+LP Sbjct: 72 DMPEWLRQVQTFGIFAAGYLARPLGGIIMAHFGDLVGRKKMFTLSILLMALPTLAIGMLP 131 Query: 139 TYASIGVAAPILLLLMRTLQGAAIGGEMPGAWVFVAEHVPANRYSFGVGSLTAGITGGIL 198 TYA+IG+ AP+LLLLMR LQGAAIGGE+PGAWVFVAEHVP R G+LTAG+T GIL Sbjct: 132 TYATIGITAPLLLLLMRVLQGAAIGGEVPGAWVFVAEHVPRKRIGIACGTLTAGLTAGIL 191 Query: 199 LGSLMGIFINSVYAPAEVAGYAWRIPFILGGVFGLVSVYLRRYLEETPVGKKX------- 251 LGSL+ +N+ + WRIPF LGG+FGL ++YLRR+L+ETP+ K+ Sbjct: 192 LGSLVATVMNTTLGHQAILEGGWRIPFFLGGIFGLFAMYLRRWLQETPIFKEMQARKTLA 251 Query: 252 -ELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLPAKLVMQANCAGT 310 ELPLK+V+ H+ V++ +TW LS +VVVILMTP+YLQ ++P +L +QAN Sbjct: 252 EELPLKSVVVNHKKEVVVSMLLTWLLSAGIVVVILMTPTYLQKQFNVPPELALQANSLAI 311 Query: 311 LMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESLIWGYALVGLFVG 370 + L IGC+ G DR G + I+G L +STW FY +P L Y L G VG Sbjct: 312 IALVIGCVVAGLAIDRFGASKTFIVGSLMLAMSTWSFYHTNLTNPSQLFPHYMLAGFCVG 371 Query: 371 SISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKADPQGPALYV 426 + P V RAFP VRFTG+SF+YN+AYA+FGGLTP+L++LW+K+ PA Y+ Sbjct: 372 IVGAVPYVMVRAFPAEVRFTGISFSYNVAYAIFGGLTPILVTLWMKSSAMAPAYYM 427 >BMEI0353 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 503 Score = 423 bits (1088), Expect = e-118, Method: Compositional matrix adjust. Identities = 217/432 (50%), Positives = 292/432 (67%), Gaps = 8/432 (1%) Query: 9 CSGGKKXTIMTTSAESAEFTGALNESQHRPLTSSDYRTLGLSALGGTLEFYDFVIYVFFA 68 C+ G + +ES T + RPL D+RTLGLSALGG LEFYDF+I+VFFA Sbjct: 38 CNEGSISATQSEESESMASTNLHTGNSPRPLNRQDFRTLGLSALGGALEFYDFIIFVFFA 97 Query: 69 AVVGKLFFPADMPEWLRMLQTFGIFAAGYLARPVGGIIIAHYGDVIGRKRMFTLSIFLMA 128 +V+G LFFP DMP+WL ++QTFGIFAAGYL RPVGGI++AH+GD GRKR+F S+FLM+ Sbjct: 98 SVIGHLFFPPDMPDWLVLIQTFGIFAAGYLVRPVGGIVLAHFGDKFGRKRVFAFSVFLMS 157 Query: 129 VPTLVIGLLPTYASIGVAAPILLLLMRTLQGAAIGGEMPGAWVFVAEHVPANRYSFGVGS 188 + TL + LPTYA++GV APILL++ R LQGAAIGGE+PGAW FVAEHVPANR G Sbjct: 158 ISTLAMAALPTYATLGVGAPILLIVFRMLQGAAIGGEVPGAWTFVAEHVPANRVGMACGF 217 Query: 189 LTAGITGGILLGSLMGIFINSVYAPAEVAGYAWRIPFILGGVFGLVSVYLRRYLEETPVG 248 L +G+T GI++GSL+ IN ++ P E++ YAWRIPF +GG+FGL++VYLRR+L ETP+ Sbjct: 218 LCSGLTLGIMIGSLIATAINWIFTPEELSAYAWRIPFFIGGIFGLLAVYLRRWLAETPIF 277 Query: 249 K--------KXELPLKTVLREHRAASVLTAGMTWCLSGAVVVVILMTPSYLQTVHHLPAK 300 K +LPL TVLR H V++ +TW LS +VV LMT ++LQ ++ Sbjct: 278 TEMKNSRLLKDKLPLGTVLRNHMHGVVISVLLTWILSAGIVVTTLMTATFLQKLYGYTPL 337 Query: 301 LVMQANCAGTLMLTIGCLAIGWLCDRIGTRASMIIGWGGLGLSTWWFYGQLPGSPESLIW 360 + A GTL L G ++ G + DRIG+ + G++T+ FY S L Sbjct: 338 QSLAATSFGTLFLMFGTVSAGAIVDRIGSGRFFAVAGIFFGVATFVFYTYAAVSLPVLFA 397 Query: 361 GYALVGLFVGSISLTPIVSTRAFPPPVRFTGLSFAYNMAYAVFGGLTPVLISLWIKADPQ 420 YA++GL VG + P V RAFP PVRF+GLSF+YN++YAVFGGLTPV+++ + +P Sbjct: 398 LYAVMGLSVGMVGAAPYVMVRAFPAPVRFSGLSFSYNVSYAVFGGLTPVIVTSLLAVNPM 457 Query: 421 GPALYVIGLSIL 432 A Y++ +++L Sbjct: 458 AHAWYLVFIAVL 469 >AGc3904 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 443 Score = 421 bits (1081), Expect = e-117, Method: Compositional matrix adjust. Identities = 217/404 (53%), Positives = 285/404 (70%), Gaps = 8/404 (1%) Query: 37 RPLTSSDYRTLGLSALGGTLEFYDFVIYVFFAAVVGKLFFPADMPEWLRMLQTFGIFAAG 96 RPL S D+RTLGLSALGG LEFYDF+I+VFFA V+G LFFP +MP+WL M+QTFGIFAAG Sbjct: 11 RPLNSQDFRTLGLSALGGALEFYDFIIFVFFATVIGHLFFPPEMPDWLVMIQTFGIFAAG 70 Query: 97 YLARPVGGIIIAHYGDVIGRKRMFTLSIFLMAVPTLVIGLLPTYASIGVAAPILLLLMRT 156 YL RP+GGI++AHYGD GRKR+F SI LMA+ TL + L+PTYA+IGVAAPILL+++R Sbjct: 71 YLVRPLGGIVLAHYGDRYGRKRVFAFSILLMALSTLGMALMPTYATIGVAAPILLIILRM 130 Query: 157 LQGAAIGGEMPGAWVFVAEHVPANRYSFGVGSLTAGITGGILLGSLMGIFINSVYAPAEV 216 LQGAAIGGE+PGAW FVAEHVP R G LT+G++ GI+LGSL+ INS++ P +V Sbjct: 131 LQGAAIGGEVPGAWTFVAEHVPFRRVGLACGFLTSGLSFGIMLGSLIAFAINSLFTPEDV 190 Query: 217 AGYAWRIPFILGGVFGLVSVYLRRYLEETPVGKKX--------ELPLKTVLREHRAASVL 268 AGYAWRIPF+LGGVFGL++VYLRR+LEETP+ + +LPL VL+ HR ++ Sbjct: 191 AGYAWRIPFLLGGVFGLIAVYLRRWLEETPIYMEMKKSKSLTDKLPLGLVLKHHRRGVII 250 Query: 269 TAGMTWCLSGAVVVVILMTPSYLQTVHHLPAKLVMQANCAGTLMLTIGCLAIGWLCDRIG 328 +A +TW LS A+VV LMT ++LQ ++ + GTL L G + G L DR+G Sbjct: 251 SALLTWVLSAAIVVTTLMTATFLQKLYGYTPTQALAGTSFGTLFLIFGVIIAGALIDRVG 310 Query: 329 TRASMIIGWGGLGLSTWWFYGQLPGSPESLIWGYALVGLFVGSISLTPIVSTRAFPPPVR 388 + + G++T+ FY S E++ Y ++GL VG P V RAFP VR Sbjct: 311 SGIFFMGASIFFGIATFTFYSYAGTSLETMFVLYGVMGLSVGMAGAVPYVMVRAFPASVR 370 Query: 389 FTGLSFAYNMAYAVFGGLTPVLISLWIKADPQGPALYVIGLSIL 432 F+GLSFAYN++YAVFGGLTP+ ++ + +P A Y++ ++ L Sbjct: 371 FSGLSFAYNVSYAVFGGLTPIGVTTALAINPMAHAWYLVFIAFL 414 >Cj0250c [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 436 Score = 348 bits (892), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 178/422 (42%), Positives = 263/422 (62%), Gaps = 20/422 (4%) Query: 37 RPLTSSDYRTLGLSALGGTLEFYDFVIYVFFAAVVGKLFFPADMPEWLRMLQTFGIFAAG 96 + L D + LGLS+LGGTLEFYDF+I+VFFA + FFP D+ + +M T+GIFAAG Sbjct: 3 KTLNQKDIKVLGLSSLGGTLEFYDFIIFVFFANYISTNFFPKDLSSFWQMFNTYGIFAAG 62 Query: 97 YLARPVGGIIIAHYGDVIGRKRMFTLSIFLMAVPTLVIGLLPTYASIGVAAPILLLLMRT 156 YLARP+GG+I+AH+GD GRKRMF +SI LM +PT + +P Y SIG +LL+ +R Sbjct: 63 YLARPLGGVILAHFGDKFGRKRMFMISILLMVIPTFTLAFIPNYESIGFLCIVLLVFIRI 122 Query: 157 LQGAAIGGEMPGAWVFVAEHVPANRYSFGVGSLTAGITGGILLGSLMGIFINSVYAPAEV 216 QG AIGGE+PGAWVFV EH P + +G LTA + GGILLGSL+ + +N +Y E+ Sbjct: 123 CQGIAIGGELPGAWVFVYEHAPQGQKRTYLGILTASVVGGILLGSLVFLIMNKIYTQEEL 182 Query: 217 AGYAWRIPFILGGVFGLVSVYLRRYLEETPVGKKX-------ELPLKTVLREHRAASVLT 269 +AWRIPF LGG+FG++S YLR++L ETPV ++ + PLK V ++ + VL+ Sbjct: 183 HEWAWRIPFFLGGIFGIISAYLRKFLRETPVFEQMKKDKALEKFPLKEVFKKAKMGIVLS 242 Query: 270 AGMTWCLSGAVVVVILMTPSYLQTVHHLPAKLVMQANCAGTLMLTIGCLAIGWLCDRIGT 329 +TW L+G +VV+IL+ PSY+ + + + G L++ +GC+ G L D+IG Sbjct: 243 MMITWVLTGCIVVMILLMPSYMAKILQINTSIQTYLQIGGILLICLGCIISGILADKIGV 302 Query: 330 RASMIIGWGGLGLSTWWFYGQL--PGSPESLIWG-YALVGLFVGSISLTPIVSTRAFPPP 386 S + G+++ ++ L + +L+ Y LV F G ++ P++ + F Sbjct: 303 IKSCVFFSVFFGIASLLYFNTLYRQNADFNLVACLYLLVCFFSGVMNFCPLIMSEVFDAK 362 Query: 387 VRFTGLSFAYNMAYAVFGGLTPVLISLWIKADPQGP---------ALYVIGLSILGVLLA 437 ++F+GLSF+YN+AYA+ GGLTP L + ++ + LYV L+I+ +L A Sbjct: 363 IKFSGLSFSYNIAYAIAGGLTPQL-AFFLHSFALNNLSNFWRFSLGLYVFFLAIIALLCA 421 Query: 438 FV 439 F+ Sbjct: 422 FI 423