BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0161.p (534 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1656 [S] COG3515 Uncharacterized protein conserved in bacteria... 122 2e-27 VCA0119 [S] COG3515 Uncharacterized protein conserved in bacteri... 118 3e-26 YPO3602 [S] COG3515 Uncharacterized protein conserved in bacteri... 86 3e-16 YPO1483 [S] COG3515 Uncharacterized protein conserved in bacteri... 85 5e-16 YPO3604 [S] COG3515 Uncharacterized protein conserved in bacteri... 70 9e-12 >PA1656 [S] COG3515 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 518 Score = 122 bits (306), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 148/538 (27%), Positives = 228/538 (42%), Gaps = 50/538 (9%) Query: 9 IGGAPVSEAQPAGTDVRDQPEFDLLQNEIAKLSSPAGSGGVDWEQVVSQAAALTSGKGKD 68 + P+S+ AG DVR E++ L+NE+ K S +G DW +++ + AL + KD Sbjct: 14 LAEQPISKDVFAGEDVRFSSEYEALENELGKALSLHENGQTDWLKILENSEALLRAQSKD 73 Query: 69 IMVACYLVGGLLQTRGLEGLAVGLQVLDEMLQAYWDGMYPPLARLRARRNALQWLMDRIA 128 + VA +L L Q GL GL +L+ + +W ++P AR RA A+ WL+ R+ Sbjct: 74 LRVAAWLTWALYQRESFPGLLAGLGLLERLCSRHWVEIHPLKARTRA--AAIAWLVPRLE 131 Query: 129 SHGSEHDWSSLPPQEA-DLVEALRDRLKSID-AFVAAKDADAPSLRPAISQVGNLLVK-- 184 +E ++P +E L L + L+ +D A A DAP L P ++ +L + Sbjct: 132 QALNE----NVPIKEQLPLFRRLAEHLEKLDTALTAQLGDDAPLLLPISRRLSGMLQRAA 187 Query: 185 ESTPPPPLVVAASSSTPSAAQSAPAVAASSVAATVGPANNAVPPTMAAIAAGPVDTLEAV 244 ++ P P +V A + AAS + A P +N A Sbjct: 188 DNQPEPGVVGAVVAQVKQ--------AASQLLAPGAPIDNERDAHKAM------------ 227 Query: 245 EQASNEALQRLADIAQWLGEGELNQPTAFRLNRIAAWAGIEQLPPANSGKTSLPGPVPQV 304 +A EA + L A WL + + A RLNR W IE +P N+ + + VP Sbjct: 228 -RAQQEAARPLC--AWWLKQKATD-LRALRLNRTMLWLPIESMPERNAEQVTALRGVP-- 281 Query: 305 QEALKAMQNRQAD---EDIVRFAEAQLAIFPFWLDLNAIAAESLQRLGPAYDSARREVIG 361 + LK+ Q R A D++ EA LA PFW D + E LQ G + A REV Sbjct: 282 ADKLKSYQERFAQGLYADLLVELEASLARAPFWFDGQRLVWECLQ--GLNAEQAMREVEM 339 Query: 362 ASAWLYARLPGIVALSFSGGMPFAGPQTREWLGSL------GQGASAGTVNAPLVDPAQA 415 A L RLPG+V L F G FA TR W+ + A L Sbjct: 340 HFALLLQRLPGLVELRFHDGSAFADAATRGWISAHVMPHLQNDSAPRKVETVALQAEWDV 399 Query: 416 AAGKARALAAEGDLGAAAQFLQQAISESQVPALRFRLRVQLCELLFSERPGANLMPFARM 475 A + + + + L AA Q L+Q + + RF ++ L L F + Sbjct: 400 ALDEVQPVLRKDGLKAAVQVLKQGMKRAHGGRARFFWQLSLARLCFLAKKYELAKTQLES 459 Query: 476 LVDEIIRFNLTDWDPPLA---SAGLTAAWRILSADDELKAETDGLLARLASIDAEAAV 530 L ++ L W+P LA L + +L + ++ + + RL +D E + Sbjct: 460 LDHQLHESGLHAWEPDLALDVLHLLHSCCELLPQNHAVRERKEDIYRRLCHLDLEVVL 517 >VCA0119 [S] COG3515 Uncharacterized protein conserved in bacteria Vch Vibrio cholerae Length = 469 Score = 118 bits (296), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 120/503 (23%), Positives = 196/503 (38%), Gaps = 56/503 (11%) Query: 1 VDLTQLSTIGGAPVSEAQPAGTDVRDQPEFDLLQNEIAKLSSPAGSGGVDWEQVVSQAAA 60 +++T+ P+S + P G + D P FD +++++ K+ S V W++V Sbjct: 1 MEMTEYRQCVAKPISSSNPVGERLVDHPLFDFIEDQMMKVGS-LSHASVQWDEVEHSTLK 59 Query: 61 LTSGKGKDIMVACYLVGGLLQTRGLEGLAVGLQVLDEMLQAYWDGMYP---PLARLRARR 117 L + KDI + YL+ L L V+ E L YW+ YP P L RR Sbjct: 60 LLGEQSKDIKLLVYLLQCLHNQVTPTRLITSFAVMSEFLNQYWNDSYPAPGPRGNL-PRR 118 Query: 118 NALQWLMDRIASHGSEHDWSSLPPQEADLVEALRDRLKSIDAFVAAKDADAPSLRPAISQ 177 + R + + D+ L +AD +L+ A+ + Sbjct: 119 KFFSQMAQRFTTVIEKFDFHHL------------------------DEADRQALQAAVEE 154 Query: 178 VGNLLVKE---STPPPPLVVAASSSTPSAAQSAPAVAASSVAATVGPANNAVPPTMAAIA 234 + K+ S +VV ++ A Q A SS A T +A Sbjct: 155 WQQAVEKQGLSSELVESVVVRITAEIKRAEQRQQVTAQSS----------AERETPSAAT 204 Query: 235 AGPVDTLEAVEQASNEALQRLADIAQWLGEGELNQPTAFRLNRIAAWAGIEQLPPAN-SG 293 P ++ + A Q L +A +L E E + RL R A W I LP G Sbjct: 205 PSPAASMVVDHSSDKAAKQTLLKVADFLAEQEFGIALSIRLRRFAVWGSITSLPDHKPDG 264 Query: 294 KTSLPG----PVPQVQEALKAMQNRQADEDIVRFAEAQLAIFPFWLDLNAIAAESLQRLG 349 +T L G V Q+ L R D + R E L + P+W + ++ Q+LG Sbjct: 265 ETLLRGMQADRVKDYQDQL-----RHPDLALWRKVEQSLTMAPYWFEGQWMSYTIAQQLG 319 Query: 350 PAYDSARREVIGASAWLYARLPGIVALSFSGGMPFAGPQTREWLGSLGQGASAGTVNAPL 409 + + + + RLP ++ L F GG PF +EWL S+GQ S G + Sbjct: 320 KS--DWCQAIAEETQQFLRRLPSLLELKFKGGEPFVSDSVKEWLASVGQ--SQGAAGQSV 375 Query: 410 VDPAQAAAGKARALAAEGDLGAAAQFLQQAISESQVPALRFRLRVQLCELLFSERPGANL 469 Q +A LA EG + A L + + P +F R+ +LL + A Sbjct: 376 GGDWQEKRKEAFQLAKEGGIAVALSMLNDGLVSAVEPRDKFYWRLLSADLLRANHLDAMA 435 Query: 470 MPFARMLVDEIIRFNLTDWDPPL 492 + L++++ ++ +W+P L Sbjct: 436 GEQYQTLLNQVTTLSVPEWEPSL 458 >YPO3602 [S] COG3515 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 465 Score = 85.5 bits (210), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 104/388 (26%), Positives = 175/388 (45%), Gaps = 48/388 (12%) Query: 12 APVSEAQPAGTDVRDQPEFDLLQNEIAKLSSPAGSGGVDWEQVVSQAAALTSGKGKDIMV 71 AP+S Q A D P+++ + ++ KL S A ++ + + QA AL S K KD + Sbjct: 18 APLSPEQTAQALADDDPQWEYIDGQMVKLGSLA-HATLNIDDIQQQAMALLSQKSKDFRL 76 Query: 72 ACYLVGGLLQTRGLEGLAVGLQVLDEMLQAYWDGMYP--PLARLRARRNALQWLMDRIAS 129 +L+ L + L + + +L E +Q +W +P PL + RR A Q ++ R S Sbjct: 77 VVHLLRTLQHGGQPDELMLAMSLLTEYVQLFWTTAWPQNPLHK---RRFAQQ-ILKRFDS 132 Query: 130 HGSEHDWSSLPPQEADLVEALRDRLKSIDAFVA-AKDADAPSLRPAISQVGNLLVKESTP 188 S Q AD EA R+ ++ + A +A + P L +V L + + P Sbjct: 133 ASSSFS------QRAD--EAQRENVQGLLAHLAQVWHSREPGL---AKEVDALRSRYARP 181 Query: 189 PPPLVVAASSSTPSAAQSAPAVAASSVAATVGPANNAVPPTMAAIAAGPVDTLEAVEQAS 248 P ++ A +S P ++++++A AA+AA PV A++ S Sbjct: 182 PERVIEAVASDEP--------LSSNTLA--------------AAMAATPVSPSLAIDNTS 219 Query: 249 NEAL-QRLADIAQWLGEGELNQPTAFRLNRIAAWAGIEQLPPANS-GKTSLPG-PVPQVQ 305 + A Q L +A L E + + FRL R A W + P A S G+T L + Sbjct: 220 DRAWRQTLLKMADLLSEQQPDAAIGFRLRRHAVWGALTAPPMAQSDGRTPLAAVSADRTA 279 Query: 306 EALKAMQNRQADEDIVRFAEAQLAIFPFWLDLNAIAAESLQRLGPAYDSARREVIGASAW 365 + L + N AD + E L + P+WLD + ++A+ +LG YD+ + + + Sbjct: 280 DYLARLAN--ADLPLWHQVEQSLTLAPYWLDGHVLSAQIALQLG--YDAVAQAIRDELSV 335 Query: 366 LYARLPGIVALSFSGGMPFAGPQTREWL 393 AR+P + L F+ PF ++ WL Sbjct: 336 FLARIPALKTLFFTDMTPFLSSESAAWL 363 >YPO1483 [S] COG3515 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 533 Score = 84.7 bits (208), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 148/550 (26%), Positives = 226/550 (41%), Gaps = 86/550 (15%) Query: 13 PVSEAQPAGTDVRDQPEFDLLQNEIAKLSSPAGSGGVDWEQVVSQAAALTSGKGKDIMVA 72 PV+ + G D F ++ E+ KLS G D A L + GKD+ VA Sbjct: 35 PVTPDKHTGEDPGYDDHFQQMREEVNKLS------GADTTLTCELAEKLFTTHGKDVRVA 88 Query: 73 CYLVGGLLQTRGLEGLAVGLQVLDEMLQAYWDGMYPPLARLRARRNALQWLMDRIASHGS 132 Y V L G GLA GL +L ++ + +G++P R +R+ AL+WL GS Sbjct: 89 TYYVWARLHRDGEAGLADGLSLLAGLITRFGEGLHP--LRTTSRKTALEWLA------GS 140 Query: 133 E-HDWSSLPPQ--EADLVEALRDRLKSIDAFVAAKDADAPSLRPAISQVGNLLVKESTPP 189 D SL P+ +AD E + L I+ ++ D +RP Q+G L Sbjct: 141 RMRDSLSLYPEVDKADF-ERIVGALALIEQRLSLWDE---GVRP---QLGGLYTA----- 188 Query: 190 PPLVVAASSSTPSAAQSAPAVAASSVAATVGPANNAVPPTMAAIAAGPVDTLEAVEQASN 249 L + S A + SS A ++ PAN A P A PV Q+ Sbjct: 189 --LENRLAQSGGLNAVVPQNSSGSSSAGSLNPANTASP------ALRPV-------QSGR 233 Query: 250 EALQRLADIAQWLGEGELNQP----TAFRLNRIAAWAGIEQLPPAN-SGKTSLPGPVPQV 304 + L + +A++L NQP + L + W + Q PP + +G+T L P P+ Sbjct: 234 DLLDQTKTLAKYLR----NQPQGWLSGHHLIKSVRWDTVHQSPPLDVNGRTRLVPPRPEY 289 Query: 305 QEALKAMQNRQADEDIVRFAEAQLA--IFPFWLDLNAIAAESLQRLGPAYDSARREVIGA 362 + LK + +Q ++ AE+ A + FWLD+ ++L + G +D + Sbjct: 290 RVQLKRLYLQQNWLALLEQAESIFAEGVNHFWLDVQWYLHQALSKAGAPFDGWASCITQD 349 Query: 363 SAWLYARLPGIVALSFSGGMPFAGPQTREWL-----------GSLGQGASAGTVNAPLVD 411 L RLPG+ L +S G PFA T W+ GS S+G L++ Sbjct: 350 LRLLLTRLPGLEGLCWSDGTPFADEVTLGWINQQVLESVSGWGSEPAAVSSGEDGILLLE 409 Query: 412 PAQAAAGKARALAAEGDLGAAAQFLQQAISESQVPALRFRLRVQLCELLFSERPGANLMP 471 P +A A A + AA +LQ S + R + ++L +E+ G N M Sbjct: 410 P------EALAQADSEGIEAALNWLQ---SRPGITTARHQWLLRLVMARVAEQYGKNDMA 460 Query: 472 FARM--LVDEIIRFNLTDWDPPLASAGLTAAWRIL--------SADDELKAETDGLLARL 521 + L L W+P L ++L S L AE + LL+ L Sbjct: 461 LHLLSGLDSSGALLTLPQWEPGLVFEVKARRLKLLRMKAQRGDSDKTRLHAEMESLLSGL 520 Query: 522 ASID-AEAAV 530 ++D A AAV Sbjct: 521 IALDPARAAV 530 >YPO3604 [S] COG3515 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 260 Score = 70.5 bits (171), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 3/118 (2%) Query: 20 AGTDVRDQPEFDLLQNEIAKLSSPAGSGGVDWEQVVSQAAALTSGKGKDIMVACYLVGGL 79 GTD R++PEF+ ++ EI K++ PA V+W + S A L G D+ A Y Sbjct: 12 TGTDPRNRPEFNAIREEINKINHPA-RPEVNWGLIESLALTLFRTHGVDLQTAVYYTLAR 70 Query: 80 LQTRGLEGLAVGLQVLDEMLQAYWDGMYPPLARLRARRNALQWLMDRIASHGSEHDWS 137 Q GL G G ++L M+ WD ++P + +AR L+W R+++ +HD++ Sbjct: 71 TQKNGLAGFTEGCELLAGMVVGQWDHLWP--EQPQARSEILEWFNTRVSNQLRQHDFT 126