BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0146.p (860 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1364 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydr... 728 0.0 RSc1269 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydr... 611 e-174 VC2087 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydro... 589 e-168 PA1585 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydro... 584 e-166 sucA [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydroge... 582 e-165 >RSp1364 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Rso Ralstonia solanacearum Length = 881 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/842 (48%), Positives = 515/842 (61%), Gaps = 25/842 (2%) Query: 26 IQSFIEAYRHEGYRIADIDPLGTLSVPEIPALLPQHHDLKDEDLALGQHRFLEGLGL--- 82 + I+AYR GYR A +DPL +PE+P L + H L R G L Sbjct: 52 VTRLIDAYRGLGYRRARLDPLSRAPLPEVPELRLRFHGLDP-----AHRRESAGAVLPTA 106 Query: 83 TNVKELTHFLSRLYCGPLGLDASGVRDESRRQWLFARLAARDPGADPATAERAAILARLA 142 T ++EL L R+YCG +GLD SGVR RR WL+AR+ A A + +L RLA Sbjct: 107 TTMQELEWQLKRVYCGSIGLDCSGVRKRQRRTWLYARMEAELTAPPLAPDRKRWLLGRLA 166 Query: 143 AAEQWEHYLQQDYPHAKRFSLEGCEALLVLMDALAERSSFYQLEQLFLAMPHRGRLNLLV 202 AAE WE + HAKRFSLEGCE+L+ L++ L + + + Q+FL +PHRGRLN LV Sbjct: 167 AAEMWERLAADRFAHAKRFSLEGCESLVPLLETLFDEAGSCGVRQVFLGLPHRGRLNALV 226 Query: 203 NLMQMPAADIVAYFDAASTTAAAAGAVDLPYHLGAETVRATAHGQLGLFMAHNPSHLESA 262 N+M A ++ D S A A DLPYHLG R T G+L L +A NPSHL+S Sbjct: 227 NVMGFDAQGMLDRLDPDSEVAIAQR--DLPYHLGGLAKRTTDAGELTLVLAPNPSHLQSV 284 Query: 263 YPVLLGMVRGYRSAHPQSPMPASVVIHGDAAFCGQGVVMESLKLSLQPGYSVGGTVHVIV 322 YPV+ GM RG+ HP +P V++HGDAAF GQGVVME+L L+ + GY+ GG VHVIV Sbjct: 285 YPVVCGMARGHLDEHPDTPC-LPVMVHGDAAFAGQGVVMETLNLTRRSGYTAGGVVHVIV 343 Query: 323 NNQIGFTTPNPLDPLNHGYCTDIARIVGAPVLHVNADQPEAVLRAARIAFDYRMQFGADV 382 NNQIGFTTPN +D + YCTD+ R+V APVLHVNAD PEAVLRAARIA +YRM+ GAD+ Sbjct: 344 NNQIGFTTPNVMDVRANDYCTDVTRMVDAPVLHVNADDPEAVLRAARIALEYRMEHGADI 403 Query: 383 VIDLVGYRRWGHAEQDTATVTQPLLHGFIDKHPPVTQLYAQAGWPGSDDGATLLAVSSQQ 442 VIDL+GYRR GH+E D VTQP LH I HP VT+ Y A S L + +Q Sbjct: 404 VIDLLGYRRLGHSEHDLTAVTQPALHAAIASHPTVTEQY-HAAVAESTRLVDLREDALRQ 462 Query: 443 VLASFRNSRPSAPAAQRRAPALAVKPDAPDLLRLR-----QFVERMTRLPEGFAAHPAVT 497 +LA SA A R A V L L + +T LPEG H V Sbjct: 463 LLAG------SAVATSRAGAAAVVNGTRHRLQPLSLQRLQTLTQTLTTLPEGVVLHDRVR 516 Query: 498 RLVAQWQDSVSSSDHACSWNFAENMAYASLLWEGQGLRISGMDVQRGTFMQRHAVWHAID 557 L W+ +++ H W AEN+A+A+LL +G G+R+SGMDV RGTFM RHAVWH+ Sbjct: 517 DLCECWRAALADGQHTVDWRMAENLAHATLLEDGHGIRLSGMDVGRGTFMHRHAVWHSQA 576 Query: 558 AAQGVQQAFWPLRQVAAPGTALEVVNSPLSEEAVVGFEYGFSVQAGPGAMVIWEAQFGDF 617 G + PL+ VA A ++VNSPL+EEA +GFEYG+SVQ + +WEAQFGDF Sbjct: 577 TLPGEGRQHVPLQHVAQRQGAFDIVNSPLTEEAALGFEYGYSVQTRT-RLTLWEAQFGDF 635 Query: 618 VNGAQIMIDQFIASGRGKWGYPSALTVLLPHGYEGVGPEHSTGYLSRMLLLCAQENMRVA 677 VNGAQ+ +DQ+IASG KWG SALT+LLPHG+EGVGPEHS+G+L R L LCA EN+RV Sbjct: 636 VNGAQVFVDQYIASGEYKWGCQSALTMLLPHGHEGVGPEHSSGFLGRFLQLCADENLRVV 695 Query: 678 YPSSSAQWFHLLRQQA-LQGDRPLVVFTPKSVLHGEVRSQSPLSALLQGDFQPLVEDADA 736 PS+S QWFHLLR+QA L +PL+ +PKS LHG RS S + L+ G F P++ D Sbjct: 696 VPSTSGQWFHLLREQATLAAPKPLIAMSPKSELHGNGRSHSRVQDLVDGAFMPVLADTGV 755 Query: 737 PPDAQVQRVVLCSGKVCYDLADGRRKAGDTRTVLLTVEQLHPFPEDRLGAVLRSYPQLEE 796 V RVVLCSGK Y+L R L+ VEQL+PFP L A L ++P E Sbjct: 756 AEPNAVTRVVLCSGKFFYELLAQREHDARADVALIRVEQLYPFPAQALMAALAAFPNRRE 815 Query: 797 VIWVQEEERKQGAWLCVRDAIEAALPLQVRLRAVTRPDTDAGPTASKARHYAQQAALVQS 856 ++W QEE+ QGAW VRD +EA LP RL +V R T +G AS H +Q + + Sbjct: 816 IVWAQEEDVNQGAWRFVRDELEACLPPGRRLASVCRHATPSGAHASVRAHQVEQRRVAAA 875 Query: 857 VF 858 VF Sbjct: 876 VF 877 >RSc1269 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Rso Ralstonia solanacearum Length = 953 Score = 611 bits (1576), Expect = e-174, Method: Compositional matrix adjust. Identities = 342/861 (39%), Positives = 492/861 (57%), Gaps = 48/861 (5%) Query: 29 FIEAYRHEGYRIADIDPLGTLSVPEIPALLPQHHDLK--DEDLALGQHRFLEGLGLTNVK 86 + AYR+ G R AD+DPL P +P L P + D+D+ G +++ Sbjct: 100 LVAAYRNVGLRWADLDPLKRQERPPVPDLDPAFYGFTEADQDIVFNASNTYFGKETMSLR 159 Query: 87 ELTHFLSRLYCGPLGLDASGVRDESRRQWLFARLAARDPGADPATAERAAILARLAAAEQ 146 EL + L YCG +G + V D+++++W RL + + ++ IL RL AAE Sbjct: 160 ELLNNLRETYCGSIGAEFMYVSDQAQKRWWQERLESIRSKPTFSAEKKKHILERLTAAEG 219 Query: 147 WEHYLQQDYPHAKRFSLEGCEALLVLMDALAERSSFYQLEQLFLAMPHRGRLNLLVNLMQ 206 E +L Y KRFSLEG E+ + MD L + + ++++ + M HRGRLN+LVN + Sbjct: 220 LERFLHTKYVGQKRFSLEGGESFIAAMDELIQHAGEKGVQEIVIGMAHRGRLNVLVNTLG 279 Query: 207 MPAADIVAYFDAASTTAAAAGAVDLPYHLGAETVRATAHGQLGLFMAHNPSHLESAYPVL 266 AD+ A F+ AG D+ YH G + T G + L +A NPSHLE PV+ Sbjct: 280 KMPADLFAEFEGKHVDDLPAG--DVKYHKGFSSDVTTLGGPVHLSLAFNPSHLEIVNPVV 337 Query: 267 LGMV--RGYRSAHPQSPMPASVVIHGDAAFCGQGVVMESLKLSLQPGYSVGGTVHVIVNN 324 G V R R +V +HGDAAF GQGVVME+L L+ GY GGT+H+++NN Sbjct: 338 EGSVKARQERRGDKTGEQVLAVQVHGDAAFAGQGVVMETLNLAQTRGYGTGGTIHIVINN 397 Query: 325 QIGFTTPNPLDPLNHGYCTDIARIVGAPVLHVNADQPEAVLRAARIAFDYRMQFGADVVI 384 QIGFTT +P D + YCTD+ +++ APVLHVN D PEAV+ A ++A D+R +F DV + Sbjct: 398 QIGFTTSDPRDSRSTLYCTDVVKMIEAPVLHVNGDDPEAVVLAMQLAIDFRTEFKKDVAV 457 Query: 385 DLVGYRRWGHAEQDTATVTQPLLHGFIDKHPPVTQLYAQAGWPGSDDGATLLAVSSQQ-- 442 D++ +R+ GH EQDT +TQPL++ I +HP +LYA D T + +++ Sbjct: 458 DIICFRKLGHNEQDTPAMTQPLMYKKIGQHPGTRKLYA-------DKLVTQSTLKTEEPD 510 Query: 443 -------------------VLASFRNSRPSAPAAQRRAPALAVK-PDAPD----LLRLRQ 478 VL++F+N A P L K D+ D + L++ Sbjct: 511 GLVQEYRAAMDAGKHTVDPVLSNFKNK-----FAVDWLPFLNRKWTDSADTAVPMAELKR 565 Query: 479 FVERMTRLPEGFAAHPAVTRLVAQWQDSVSSSDHACSWNFAENMAYASLLWEGQGLRISG 538 ER+T +P+ F HP V R+V + + + A W E++A+ASL+ G +RI+G Sbjct: 566 LAERITAIPDHFKVHPLVERVVND-RAKMGQGEQALDWGMGEHLAFASLVASGYPVRITG 624 Query: 539 MDVQRGTFMQRHAVWHAIDAAQGVQQAFWPLRQVAAPGTALEVVNSPLSEEAVVGFEYGF 598 D RGTF RHAV H + + ++ PL+ V+ V++S LSEEAV+GFEYG+ Sbjct: 625 QDAGRGTFTHRHAVLHDQNRERWDAGSYIPLQNVSDNQAPFTVIDSVLSEEAVMGFEYGY 684 Query: 599 SVQAGPGAMVIWEAQFGDFVNGAQIMIDQFIASGRGKWGYPSALTVLLPHGYEGVGPEHS 658 S A P +VIWEAQFGDF NGAQ++IDQFI+SG KWG S LT++LPHGYEG GPEHS Sbjct: 685 S-SAEPNTLVIWEAQFGDFANGAQVVIDQFISSGEVKWGRASGLTLMLPHGYEGQGPEHS 743 Query: 659 TGYLSRMLLLCAQENMRVAYPSSSAQWFHLLRQQALQGDR-PLVVFTPKSVLHGEVRSQS 717 + + R L LCA NM+V P++ AQ FHLLR+Q ++ R PL++ TPKS+L + + S Sbjct: 744 SARMERYLQLCADHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIIMTPKSLLRSK-DAVS 802 Query: 718 PLSALLQGDFQPLVEDADAPPDAQVQRVVLCSGKVCYDLADGRRKAGDTRTVLLTVEQLH 777 PL+ L +G F+ ++ D + A+V+R+V CSGKV YDL + R++ G T T ++ VEQL+ Sbjct: 803 PLTDLAKGHFETVIADHEELNAAKVKRIVACSGKVYYDLVNARKERGLTDTAIIRVEQLY 862 Query: 778 PFPEDRLGAVLRSYPQLEEVIWVQEEERKQGAWLCVRDAIEAALPLQVRLRAVTRPDTDA 837 PFP A L+ YP L EV+W Q+E + QGAW V+ I + +L RP + + Sbjct: 863 PFPHKAFAAELKKYPNLAEVVWCQDEPQNQGAWFFVQHYIMENMSEGQKLGYAGRPASAS 922 Query: 838 GPTASKARHYAQQAALVQSVF 858 A+H QQ AL+ + F Sbjct: 923 PAVGYYAKHNEQQKALIDAAF 943 >VC2087 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Vch Vibrio cholerae Length = 936 Score = 589 bits (1519), Expect = e-168, Method: Compositional matrix adjust. Identities = 341/866 (39%), Positives = 479/866 (55%), Gaps = 38/866 (4%) Query: 13 QMSDARQALAHARIQSFIEAYRHEGYRIADIDPLGTLSVPEIPALLPQHHDLKDEDL--A 70 Q+SD ++ I AYR G+ A +DPLG + PE+ L P H+L ED+ Sbjct: 80 QVSDPEVDAKQVKVLQLINAYRFRGHEAAKLDPLGLWNRPEVAELNPSFHNLTQEDMEET 139 Query: 71 LGQHRFLEGLGLTNVKELTHFLSRLYCGPLGLDASGVRDESRRQWLFARLAARDPGADPA 130 F G +K++ L ++YCG +G + + D +++W+ RL + Sbjct: 140 FNVGSFAIGKDTMKLKDIYQSLQKIYCGSVGAEYMHITDTEQKRWIQQRLEPVVGTPVFS 199 Query: 131 TAERAAILARLAAAEQWEHYLQQDYPHAKRFSLEGCEALLVLMDALAERSSFYQLEQLFL 190 E+ L L AAE E YL +P AKRFSLEG +AL+ + + + + ++ + Sbjct: 200 KEEKRTFLEELTAAEGLERYLGAKFPGAKRFSLEGGDALVPMTKEMIRHAGASGMREVVI 259 Query: 191 AMPHRGRLNLLVNLMQMPAADIVAYFDAASTTAAAAGAVDLPYHLGAETVRATAHGQLGL 250 M HRGRLN+LVN++ D+ F A G D+ YH G AT G + L Sbjct: 260 GMAHRGRLNMLVNVLGKKPQDLFDEF--AGKHGEGWGTGDVKYHQGFSADFATPGGDVHL 317 Query: 251 FMAHNPSHLESAYPVLLGMVRGY--RSAHPQSPMPASVVIHGDAAFCGQGVVMESLKLSL 308 +A NPSHLE PV++G VR R + IHGD+A GQGVV E+ +S Sbjct: 318 ALAFNPSHLEIVNPVVMGSVRARQDRLGDEDGSKVLPITIHGDSAIAGQGVVAETFNMSQ 377 Query: 309 QPGYSVGGTVHVIVNNQIGFTTPNPLDPLNHGYCTDIARIVGAPVLHVNADQPEAVLRAA 368 G+ VGGTV ++VNNQ+GFTT NP D + YCTDIA++V AP+ HVN+D PEAV Sbjct: 378 ARGFCVGGTVRIVVNNQVGFTTSNPRDTRSTMYCTDIAKMVQAPIFHVNSDDPEAVAFVT 437 Query: 369 RIAFDYRMQFGADVVIDLVGYRRWGHAEQDTATVTQPLLHGFIDKHPPVTQLYAQAGWPG 428 R+A DYR +F DVVIDLV YRR GH E D TQPL++ I KHP +LYA Sbjct: 438 RLALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPLMYQKIKKHPTPRKLYADVL--- 494 Query: 429 SDDGATLLAVSSQQVLASFRNS-----------RPSAPAAQRRAPALAVKPDAP-----D 472 ++ G L ++Q ++ +R++ RP A + +P L P Sbjct: 495 TERGECDLETATQ-LVNEYRDALDHGEVVVKEWRPMAMHSVDWSPYLGHDWHIPWNSEYA 553 Query: 473 LLRLRQFVERMTRLPEGFAAHPAVTRLVAQWQDSVS--SSDHACSWNFAENMAYASLLWE 530 + RL+ R+ + PE H V ++ +QD +S S + W AE +AYA+LL + Sbjct: 554 MERLQDLGRRVCQYPESHVLHSRVEKI---YQDRLSMISGEKMLDWGMAETLAYATLLDD 610 Query: 531 GQGLRISGMDVQRGTFMQRHAVWHAIDAAQGVQQAFWPLRQVAAPGTALEVVNSPLSEEA 590 G+ +RISG D RGTF RHAV H + A + PL Q+ A EV +S LSEEA Sbjct: 611 GKRIRISGQDSGRGTFFHRHAVLHNQNDAS----TYIPLSQIHAGQGPFEVFDSVLSEEA 666 Query: 591 VVGFEYGFSVQAGPGAMVIWEAQFGDFVNGAQIMIDQFIASGRGKWGYPSALTVLLPHGY 650 V+ FEYG++ A P + +WEAQFGDF NGAQ++IDQFI+SG KWG LT+LLPHGY Sbjct: 667 VLAFEYGYAT-AEPSGLTLWEAQFGDFANGAQVVIDQFISSGEQKWGRLCGLTMLLPHGY 725 Query: 651 EGVGPEHSTGYLSRMLLLCAQENMRVAYPSSSAQWFHLLRQQALQ-GDRPLVVFTPKSVL 709 EG GPEHS+ L R L LCA++NM+V PS+ AQ +H++R+Q ++ RPLVV +PKS+L Sbjct: 726 EGQGPEHSSARLERYLQLCAEQNMQVVVPSTPAQVYHMIRRQVVRPMRRPLVVMSPKSLL 785 Query: 710 HGEVRSQSPLSALLQGDFQPLVEDADAPPDAQVQRVVLCSGKVCYDLADGRRKAGDTRTV 769 + S + L G FQP + + DA +QV+RVV CSGKV YDL + RR Sbjct: 786 RHPL-CVSSMEDLAHGTFQPAIGEIDALNPSQVKRVVFCSGKVYYDLLEQRRANEQQDVA 844 Query: 770 LLTVEQLHPFPEDRLGAVLRSYPQLEEVIWVQEEERKQGAWLCVRDAIEAALPLQVRLRA 829 ++ +EQL+PFP + + A + +Y + + +W QEE + QGAW + AA+P L+ Sbjct: 845 IVRIEQLYPFPLEEVQAAIANYTNVVDYVWCQEEPQNQGAWYSSQHNFRAAIPAGADLKY 904 Query: 830 VTRPDTDAGPTASKARHYAQQAALVQ 855 RP + + + H QQ AL++ Sbjct: 905 AGRPASASPAVGYMSVHMKQQKALIE 930 >PA1585 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Pae Pseudomonas aeruginosa Length = 943 Score = 584 bits (1506), Expect = e-166, Method: Compositional matrix adjust. Identities = 343/881 (38%), Positives = 476/881 (54%), Gaps = 51/881 (5%) Query: 8 AGSTEQMSDARQALAHARIQSFIEAYRHEGYRIADIDPLGTLSVPEIPALLPQHHDLK-- 65 AGS + +Q + I AYR G++ + +DPLG P L H+ L Sbjct: 82 AGSVSSEHEKKQV----EVLRLIHAYRLRGHQASTLDPLGLWQRPAPADLSIDHYGLTGA 137 Query: 66 DEDLALGQHRFLEGLGLTNVKELTHFLSRLYCGPLGLDASGVRDESRRQWLFARLAARDP 125 D D G ++E+ L YCG G + + D +R+W RL + Sbjct: 138 DLDTTFRTGELYIGKEEATLREIVDSLKSTYCGTFGAEFMHIVDSEQRKWFLQRLESVRG 197 Query: 126 GADPATAERAAILARLAAAEQWEHYLQQDYPHAKRFSLEGCEALLVLMDALAERSSFYQL 185 + RA +L RL AAE E YL YP KRF LEG E+L+ ++D + +R Y Sbjct: 198 RPGFSAEARAHLLERLTAAEGLEKYLGTKYPGTKRFGLEGGESLIPMVDEIIQRCGSYGA 257 Query: 186 EQLFLAMPHRGRLNLLVNLMQMPAADIVAYFDAASTTAAAAGAVDLPYHLGAETVRATAH 245 +++ + M HRGRLN+LVN + D+ F+ +G D+ YH G + T+ Sbjct: 258 KEIVIGMAHRGRLNVLVNTLGKNPRDLFDEFEGKKIVELGSG--DVKYHQGFSSNVMTSG 315 Query: 246 GQLGLFMAHNPSHLESAYPVLLGMVRGYRSAHPQSPMPASV--VIHGDAAFCGQGVVMES 303 G++ L +A NPSHLE PV+ G VR + S V IHGDAAF GQGVVME+ Sbjct: 316 GEVHLALAFNPSHLEIVSPVVEGSVRARQDRRKDSSGDKVVPISIHGDAAFAGQGVVMET 375 Query: 304 LKLSLQPGYSVGGTVHVIVNNQIGFTTPNPLDPLNHGYCTDIARIVGAPVLHVNADQPEA 363 ++S Y GGT+H+++NNQ+GFTT D + Y TD+A+++ AP+ HVN D PEA Sbjct: 376 FQMSQTRAYKTGGTIHLVINNQVGFTTSRQDDARSTEYATDVAKMIQAPIFHVNGDDPEA 435 Query: 364 VLRAARIAFDYRMQFGADVVIDLVGYRRWGHAEQDTATVTQPLLHGFIDKHPPVTQLYAQ 423 VL ++A DYRMQF DVVIDLV YRR GH E D + TQPL++ I K +LYA Sbjct: 436 VLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMYQQIAKQRTTRELYAD 495 Query: 424 AGWPGSDDGATLLAVSSQQVLASFRNSRPSAPAAQRRAPALAVKPDAP------------ 471 A +S++QV + + R + +L +P+ Sbjct: 496 ALVNAG-------VLSAEQVQSKIDDYRDALDNGLHVVKSLVKEPNKELFVDWRPYLGHA 548 Query: 472 ---------DLLRLRQFVERMTRLPEGFAAHPAVTRLVAQWQDSVSSSDHACSWNFAENM 522 DL L++ +M +PEGF V+++ Q +++ +W FAE + Sbjct: 549 WTARHDTRFDLKTLQELSSKMLEVPEGFVVQRQVSKIYEDRQ-KMAAGGLPINWGFAETL 607 Query: 523 AYASLLWEGQGLRISGMDVQRGTFMQRHAVWHAIDAAQGVQQAFWPLRQVAAPGTALEVV 582 AYA+LL+EG +R++G DV RGTF RHAV H Q + PL + L++ Sbjct: 608 AYATLLFEGHPVRMTGQDVGRGTFSHRHAVLHN----QKDDSVYVPLANLFDGQPRLDIY 663 Query: 583 NSPLSEEAVVGFEYGFSVQAGPGAMVIWEAQFGDFVNGAQIMIDQFIASGRGKWGYPSAL 642 +S LSEEAV+ FEYGF+ P ++VIWEAQFGDF NGAQ++IDQFI SG KWG L Sbjct: 664 DSFLSEEAVLAFEYGFATTT-PNSLVIWEAQFGDFANGAQVVIDQFITSGESKWGRLCGL 722 Query: 643 TVLLPHGYEGVGPEHSTGYLSRMLLLCAQENMRVAYPSSSAQWFHLLRQQALQGDR-PLV 701 T+LLPHGYEG GPEHS+ L R L LCA++N++V P++ AQ +H+LR+Q ++ R PLV Sbjct: 723 TMLLPHGYEGQGPEHSSARLERYLQLCAEQNIQVCVPTTPAQVYHMLRRQVIRPLRKPLV 782 Query: 702 VFTPKSVLHGEVRSQSPLSALLQGDFQPLVEDADAPPDAQVQRVVLCSGKVCYDLADGRR 761 V TPKS+L ++ + S L L G FQ ++ + D+ +V RVVLCSGKV YDL + RR Sbjct: 783 VMTPKSLLRHKL-AISTLEDLANGSFQTVIPEIDSLDPKKVDRVVLCSGKVYYDLLEKRR 841 Query: 762 KAGDTRTVLLTVEQLHPFPEDRLGAVLRSYPQLEEVIWVQEEERKQGAWLC----VRDAI 817 G T ++ +EQL+PFPED L VL Y L+ ++W QEE QGAW C +R I Sbjct: 842 AEGREDTAIVRIEQLYPFPEDDLAEVLAPYKNLKHIVWCQEEPMNQGAWFCSQHHMRRVI 901 Query: 818 EAALPLQVRLRAVTRPDTDAGPTASKARHYAQQAALVQSVF 858 AA + L R + A + H QQ L+Q F Sbjct: 902 -AAHKKGLNLEYAGREGSAAPACGYASMHAEQQEKLLQDAF 941 >sucA [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Eco Escherichia coli K12 Length = 933 Score = 582 bits (1500), Expect = e-165, Method: Compositional matrix adjust. Identities = 336/859 (39%), Positives = 473/859 (55%), Gaps = 28/859 (3%) Query: 14 MSDARQALAHARIQSFIEAYRHEGYRIADIDPLGTLSVPEIPALLPQHHDLKDEDL--AL 71 +SD + ++ I AYR G++ A++DPLG ++ L P HDL + D Sbjct: 80 ISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETF 139 Query: 72 GQHRFLEGLGLTNVKELTHFLSRLYCGPLGLDASGVRDESRRQWLFARLAARDPGADPAT 131 F G + EL L + YCGP+G + + ++W+ R+ + A + Sbjct: 140 NVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIES--GRATFNS 197 Query: 132 AERAAILARLAAAEQWEHYLQQDYPHAKRFSLEGCEALLVLMDALAERSSFYQLEQLFLA 191 E+ L+ L AAE E YL +P AKRFSLEG +AL+ ++ + + ++ L Sbjct: 198 EEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLG 257 Query: 192 MPHRGRLNLLVNLMQMPAADIVAYFDAASTTAAAAGAVDLPYHLGAETVRATAHGQLGLF 251 M HRGRLN+LVN++ D+ F A G D+ YH+G + T G + L Sbjct: 258 MAHRGRLNVLVNVLGKKPQDLFDEF--AGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLA 315 Query: 252 MAHNPSHLESAYPVLLGMVRGY--RSAHPQSPMPASVVIHGDAAFCGQGVVMESLKLSLQ 309 +A NPSHLE PV++G VR R P S + IHGDAA GQGVV E+L +S Sbjct: 316 LAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKA 375 Query: 310 PGYSVGGTVHVIVNNQIGFTTPNPLDPLNHGYCTDIARIVGAPVLHVNADQPEAVLRAAR 369 GY VGGTV +++NNQ+GFTT NPLD + YCTDI ++V AP+ HVNAD PEAV R Sbjct: 376 RGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTR 435 Query: 370 IAFDYRMQFGADVVIDLVGYRRWGHAEQDTATVTQPLLHGFIDKHPPVTQLYA----QAG 425 +A D+R F DV IDLV YRR GH E D + TQPL++ I KHP ++YA Q Sbjct: 436 LALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEK 495 Query: 426 WPGSDDGATLLAVSSQQVLAS---FRNSRPSAPAAQRRAPALAVK-----PDAPDLLRLR 477 +D ++ + + A RP + +P L + P+ ++ RL+ Sbjct: 496 VATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQ 555 Query: 478 QFVERMTRLPEGFAAHPAVTRLVAQWQDSVSSSDHACSWNFAENMAYASLLWEGQGLRIS 537 + +R++ +PE V ++ Q ++++ + W AEN+AYA+L+ EG +R+S Sbjct: 556 ELAKRISTVPEAVEMQSRVAKIYGDRQ-AMAAGEKLFDWGGAENLAYATLVDEGIPVRLS 614 Query: 538 GMDVQRGTFMQRHAVWHAIDAAQGVQQAFWPLRQVAAPGTALEVVNSPLSEEAVVGFEYG 597 G D RGTF RHAV H Q + PL+ + A V +S LSEEAV+ FEYG Sbjct: 615 GEDSGRGTFFHRHAVIHN----QSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYG 670 Query: 598 FSVQAGPGAMVIWEAQFGDFVNGAQIMIDQFIASGRGKWGYPSALTVLLPHGYEGVGPEH 657 ++ A P + IWEAQFGDF NGAQ++IDQFI+SG KWG L +LLPHGYEG GPEH Sbjct: 671 YAT-AEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEH 729 Query: 658 STGYLSRMLLLCAQENMRVAYPSSSAQWFHLLRQQALQG-DRPLVVFTPKSVLHGEVRSQ 716 S+ L R L LCA++NM+V PS+ AQ +H+LR+QAL+G RPLVV +PKS+L + + Sbjct: 730 SSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPL-AV 788 Query: 717 SPLSALLQGDFQPLVEDADAPPDAQVQRVVLCSGKVCYDLADGRRKAGDTRTVLLTVEQL 776 S L L G F P + + D V+RVV+CSGKV YDL + RRK ++ +EQL Sbjct: 789 SSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQL 848 Query: 777 HPFPEDRLGAVLRSYPQLEEVIWVQEEERKQGAWLCVRDAIEAALPLQVRLRAVTRPDTD 836 +PFP + VL+ + +++ +W QEE QGAW C + +P LR RP + Sbjct: 849 YPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASA 908 Query: 837 AGPTASKARHYAQQAALVQ 855 + + H QQ LV Sbjct: 909 SPAVGYMSVHQKQQQDLVN 927