BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0112.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0745 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 369 e-102 RSp0648 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso ... 294 2e-79 AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 179 6e-45 CAC2712 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Cac ... 167 3e-41 SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ss... 162 9e-40 >PA0745 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 272 Score = 369 bits (947), Expect = e-102, Method: Compositional matrix adjust. Identities = 185/253 (73%), Positives = 208/253 (82%) Query: 7 LKLEKCGHTAVLTLSNPPANTWTREALADLTRLVKDLNADREIYTLVVTGEGEKFFSAGA 66 L +EK GHTA++T+++PPANTW R++L L +L++ LN D +IY LVVTG+G KFFSAGA Sbjct: 19 LTVEKHGHTALITINHPPANTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSAGA 78 Query: 67 DLKLFADGDKAMAREMARRFGEAFETLSGFRGVSIAAINGYAMGGGLECALACDIRIAEE 126 DL +FADGDKA AREMARRFGEAFE L FRGVSIAAINGYAMGGGLECALACDIRIAE Sbjct: 79 DLNMFADGDKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLECALACDIRIAER 138 Query: 127 QAQMALPEAAVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVNAETALRIGLVEEVVPKG 186 QAQMALPEAAVGLLPCAGGTQ LPWLVGEGWAKRMILC ERV+AETALRIGLVE+VV G Sbjct: 139 QAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSG 198 Query: 187 QARERALALALQAEKQSPSSVAASKQLIQGARHNPLGTILQTERELFVDLFDTQDQKEGV 246 +AR AL LA + +QSP ++ K LIQGAR T L ERE FVDLFD QD +EGV Sbjct: 199 EARGAALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERERFVDLFDAQDTREGV 258 Query: 247 NAFLEKRAPSWKN 259 NAFLEKR P W+N Sbjct: 259 NAFLEKRDPKWRN 271 >RSp0648 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso Ralstonia solanacearum Length = 266 Score = 294 bits (752), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 162/249 (65%), Positives = 180/249 (72%), Gaps = 1/249 (0%) Query: 13 GHTAVLTLSNPPANTWTREALADLTRLVKDLNADREIYTLVVTGEGEKFFSAGADLKLFA 72 G A+LTLS PPAN +T E L L V+ L+AD + LV+TG+G KFFSAGADL FA Sbjct: 10 GTVALLTLSRPPANAFTPEGLRQLQATVETLDADPRVRALVITGDGPKFFSAGADLNTFA 69 Query: 73 DGDKAMAREMARRFGEAFETLSGFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMAL 132 GD+ +ARE A RFG AFE L R V IAAINGYAMGGGLECALACDIRIAE AQ+A+ Sbjct: 70 SGDRDVAREAAARFGAAFEALQNARPVVIAAINGYAMGGGLECALACDIRIAERHAQLAV 129 Query: 133 PEAAVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVNAETALRIGLVEEVVPKGQARERA 192 PE AVGLL C GTQ LPWLVGEGWAKRMIL GER++A+TALRIGLVEEVV G ARE A Sbjct: 130 PETAVGLLCCGCGTQTLPWLVGEGWAKRMILTGERIDAQTALRIGLVEEVVDTGAAREAA 189 Query: 193 LALALQAEKQSPSSVAASKQLIQGARHN-PLGTILQTERELFVDLFDTQDQKEGVNAFLE 251 LA+A + SP +V SK LI ARH P L ERE FVDLF DQ+EGVNAFLE Sbjct: 190 LAMARRVTTLSPRAVTFSKALIHQARHGVPRTAALAVERERFVDLFGHPDQREGVNAFLE 249 Query: 252 KRAPSWKNA 260 KR P W A Sbjct: 250 KRPPRWHTA 258 >AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 256 Score = 179 bits (454), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 107/256 (41%), Positives = 154/256 (60%), Gaps = 10/256 (3%) Query: 7 LKLEKCGHTAVLTLSNPPA----NTWTREALADLTRLVKDLNADREIYTLVVTGEGEKFF 62 +KLE G AV TL+ P +T TR LA++ ++++ L++TG G K F Sbjct: 5 VKLELDGEIAVATLNRPEKLNALDTKTRMELAEVIEGIEEVA-----RVLIITGSG-KAF 58 Query: 63 SAGADLKLFADGDKAMAREMARRFGEAFETLSGFRGVSIAAINGYAMGGGLECALACDIR 122 +AGAD+ D A E + + F + IAA+NGY +GGG E A+ACDIR Sbjct: 59 AAGADINELLQRDAIKAFEATKLGTDLFSRIEELEIPVIAAVNGYTLGGGCELAMACDIR 118 Query: 123 IAEEQAQMALPEAAVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVNAETALRIGLVEEV 182 IA E+A+ PE + ++P AGGTQ LP LVG G AK+++L GE ++A+TALRIGLVEEV Sbjct: 119 IASEKAKFGQPEINLAIIPGAGGTQRLPRLVGLGMAKKLVLTGEIIDAQTALRIGLVEEV 178 Query: 183 VPKGQARERALALALQAEKQSPSSVAASKQLIQGARHNPLGTILQTERELFVDLFDTQDQ 242 V + ERA +A + ++SP +V +K+ + + + PL L+ E LF LF ++D Sbjct: 179 VEHERLMERAKEVAAKIIEKSPLAVKVAKKALNASINMPLKEGLRYEASLFALLFSSEDA 238 Query: 243 KEGVNAFLEKRAPSWK 258 KEG+ AFLEKR P ++ Sbjct: 239 KEGMRAFLEKRKPEFR 254 >CAC2712 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Cac Clostridium acetobutylicum Length = 261 Score = 167 bits (422), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 100/261 (38%), Positives = 144/261 (55%), Gaps = 10/261 (3%) Query: 5 TNLKLEKCGHTAVLTLSNPPA-NTWTREALADLTRLVKDLNADREIYTLVVTGEGEKFFS 63 N+ LEK G AV+T++ P A N + L ++ ++ ++ D E+ +++TG GEK F Sbjct: 4 NNVILEKEGKVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFV 63 Query: 64 AGADLKLFADGDKAMAREMARRFG----EAFETLSGFRGVSIAAINGYAMGGGLECALAC 119 AGAD+ K M R+FG + F L IAA+NG+A+GGG E A++C Sbjct: 64 AGADISEM----KEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSC 119 Query: 120 DIRIAEEQAQMALPEAAVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVNAETALRIGLV 179 DIRIA A+ PE +G+ P GGTQ L LVG G AK++I + + A+ ALRIGLV Sbjct: 120 DIRIASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLV 179 Query: 180 EEVVPKGQARERALALALQAEKQSPSSVAASKQLIQGARHNPLGTILQTERELFVDLFDT 239 +VV + A +A + +P +V SKQ I + T L E E F + F T Sbjct: 180 NKVVEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFST 239 Query: 240 QDQKEGVNAFLEKRA-PSWKN 259 +DQK+ + AF+EKR +KN Sbjct: 240 EDQKDAMTAFIEKRKIEGFKN 260 >SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 256 Score = 162 bits (409), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 95/233 (40%), Positives = 140/233 (60%), Gaps = 2/233 (0%) Query: 26 NTWTREALADLTRLVKDLNADREIYTLVVTGEGEKFFSAGADLKLFADGDKAMAREMARR 85 N E +++L + + +L + ++ +++TG G + FSAGAD+ F + + R Sbjct: 24 NALNPELVSELDKSLDELESRSDVRVVIITGNG-RAFSAGADVSSFIT-LRPIDVIRLRT 81 Query: 86 FGEAFETLSGFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEAAVGLLPCAGG 145 ++ + IA ING+A+GGGLE A+ACDIRIA E AQ+ PE +G++P AGG Sbjct: 82 LRNVVNKIALYTKPIIAGINGFALGGGLELAMACDIRIASEVAQLGQPEINIGIIPGAGG 141 Query: 146 TQNLPWLVGEGWAKRMILCGERVNAETALRIGLVEEVVPKGQARERALALALQAEKQSPS 205 TQ LP LVG+G AK MI G+ V+AE A ++GLV+ VVP + E +AL+ ++SP Sbjct: 142 TQRLPRLVGKGKAKLMIYTGDMVSAEDAYKMGLVDLVVPSNRFEEEVRRVALKIAEKSPI 201 Query: 206 SVAASKQLIQGARHNPLGTILQTERELFVDLFDTQDQKEGVNAFLEKRAPSWK 258 S+ A+K I+ + + T E LF LF T+D +EGV AFLEKR P +K Sbjct: 202 SLLAAKLAIELGYESNIWTGQTLESTLFGLLFTTKDVEEGVKAFLEKRKPQFK 254