BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0003.p (269 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr8130 [R] COG0457 FOG Mlo Mesorhizobium loti 98 2e-20 MA1362 [R] COG0457 FOG Mac Methanosarcina acetivorans str.C2A 94 3e-19 MTH83 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus 91 2e-18 MTH68 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus 91 3e-18 mll2645 [R] COG0457 FOG Mlo Mesorhizobium loti 88 2e-17 >mlr8130 [R] COG0457 FOG Mlo Mesorhizobium loti Length = 289 Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 81/237 (34%), Positives = 114/237 (48%), Gaps = 6/237 (2%) Query: 15 ALQHYNAGRAAEAEQACHALLALVPQHPAAHQLLAMLALDRQALAQARQHILLSLAPRPQ 74 A+ +N+G A Q C L P PA LLA + R L+ AR HI SLA R Sbjct: 16 AVAAFNSGNHGLAMQLCELGLKQHPDDPALCHLLAAVLFARADLSGARTHIETSLAARAD 75 Query: 75 HVPSLLMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHL--GTSLSAVGRHAEAVAA 132 +VP+L++A +IA A+G A+Q D AA+ SQA + + G A Sbjct: 76 NVPALILACKIARADGRFEAALQQLDRAAKLS---SQAEIPIERARTFDQAGNALAAREW 132 Query: 133 LRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMK 192 + P++ EA LG + G A E F + WF+LGL QDM+ Sbjct: 133 WTLVLQRDPKSEEAAARLGRLAWQRGASVEA-EGFLERAVASGGHPSAWFDLGLVRQDMR 191 Query: 193 EGAAAVDAFARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTALRLGXAAAAVV 249 + AA A+ R L++ P +AA+NLGV LQE +D A+ A+ TA RL + V+ Sbjct: 192 KFGAAAQAYRRVLEMSPDAPEAAVNLGVVLQETGDLDGAMLAYSTAYRLRPSTFGVI 248 >MA1362 [R] COG0457 FOG Mac Methanosarcina acetivorans str.C2A Length = 400 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 108/233 (46%), Gaps = 2/233 (0%) Query: 15 ALQHYNAGRAAEAEQACHALLALVPQHPAAHQLLAMLALDRQALAQARQHILLSLAPRPQ 74 A + G A +A L L P +P A A+ + +A + L P Sbjct: 128 AFSYSQVGEYERAVEAYGKALELRPDYPNAWYGKALNLSQAGSYEEAVEAYEKVLEESPD 187 Query: 75 HVPSLLMAGRIALAE-GDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAAL 133 + + G IAL + G A+ +D A P +A ++ G L ++G H +A+ A Sbjct: 188 YKEAWAGKG-IALGQMGRYDEAIIAYDKAIEIDPGFLEAWYYKGVDLDSLGSHRQALKAY 246 Query: 134 RQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKE 193 +AV L P+ +A N+G L L + A AF ++ + E ++ W+N G TL M Sbjct: 247 EKAVELDPENDDAWNNMGIDLENLEKYEEAINAFDKAIAINSENSDVWYNKGFTLSQMHR 306 Query: 194 GAAAVDAFARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTALRLGXAAA 246 AV+A+ +A QL P Y +A +LG L ++ ++AL+ + AL L AA Sbjct: 307 FEEAVEAYRKATQLDPEYLEAYTSLGFVLAQLKNFEEALETYEKALELDQGAA 359 Score = 77.4 bits (189), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 60/242 (24%), Positives = 108/242 (44%), Gaps = 10/242 (4%) Query: 5 PAAPDQIMGAALQHYNAGRAAEAEQACHALLALVPQHPAAHQ-----LLAMLALDRQALA 59 P P+ G AL AG EA +A +L P + A L M D +A Sbjct: 152 PDYPNAWYGKALNLSQAGSYEEAVEAYEKVLEESPDYKEAWAGKGIALGQMGRYDEAIIA 211 Query: 60 QARQHILLSLAPRPQHVPSLLMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTS 119 + ++ P + + G + G A++ ++ A PE A ++G Sbjct: 212 YDK-----AIEIDPGFLEAWYYKGVDLDSLGSHRQALKAYEKAVELDPENDDAWNNMGID 266 Query: 120 LSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAE 179 L + ++ EA+ A +A+A+ + + N G L ++ A EA++++ +L PE E Sbjct: 267 LENLEKYEEAINAFDKAIAINSENSDVWYNKGFTLSQMHRFEEAVEAYRKATQLDPEYLE 326 Query: 180 TWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTAL 239 + +LG L +K A++ + +AL+L G AD+ V L + R ++A A+R A+ Sbjct: 327 AYTSLGFVLAQLKNFEEALETYEKALELDQGAADSWFGKAVCLSFLGREEEAEDAYRKAV 386 Query: 240 RL 241 + Sbjct: 387 EI 388 Score = 65.1 bits (157), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 38/143 (26%), Positives = 70/143 (48%) Query: 99 FDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSALRELG 158 FD A P+ + +L + GR EA+ ++AV + + + N+ + ++G Sbjct: 76 FDKAIEKDPKNIYLLNNKAAALESFGRFEEALKLYQKAVEINSEDADLWNNMAFSYSQVG 135 Query: 159 ELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADAALNL 218 E A EA+ ++ LRP+ W+ L L AV+A+ + L+ P Y +A Sbjct: 136 EYERAVEAYGKALELRPDYPNAWYGKALNLSQAGSYEEAVEAYEKVLEESPDYKEAWAGK 195 Query: 219 GVALQEIHRMDDALQAFRTALRL 241 G+AL ++ R D+A+ A+ A+ + Sbjct: 196 GIALGQMGRYDEAIIAYDKAIEI 218 Score = 60.8 bits (146), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 32/124 (25%), Positives = 63/124 (50%) Query: 117 GTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPE 176 G L +G+ EA+ A +A+ P+ + + N +AL G A + ++++ + E Sbjct: 60 GLDLLKLGKFNEAIIAFDKAIEKDPKNIYLLNNKAAALESFGRFEEALKLYQKAVEINSE 119 Query: 177 VAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADAALNLGVALQEIHRMDDALQAFR 236 A+ W N+ + + E AV+A+ +AL+LRP Y +A + L + ++A++A+ Sbjct: 120 DADLWNNMAFSYSQVGEYERAVEAYGKALELRPDYPNAWYGKALNLSQAGSYEEAVEAYE 179 Query: 237 TALR 240 L Sbjct: 180 KVLE 183 >MTH83 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus Length = 379 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 86/148 (58%) Query: 95 AVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSAL 154 A++ +D + P+ +A + G + +GR+ E++ +A+ + P+ EA N G L Sbjct: 205 ALKCYDKVLQLNPQDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNKGVVL 264 Query: 155 RELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADA 214 ELG A E ++++ + PE +TW N GL L+++ + A++ F +AL++ P +ADA Sbjct: 265 SELGRYEEALECYEKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEINPEFADA 324 Query: 215 ALNLGVALQEIHRMDDALQAFRTALRLG 242 G+ L+++ + +++L+ ++ AL+L Sbjct: 325 WKWKGIILEDLKKPEESLKCYKKALKLN 352 Score = 79.7 bits (195), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 53/223 (23%), Positives = 103/223 (46%), Gaps = 40/223 (17%) Query: 55 RQALAQARQHILLSLAPRPQHVPSLLMAGRIALAE-GDPATAVQYFDAAARHQPELSQAH 113 ++AL + R+ +L RP + P +L I L + P A++ ++ ++ P+L++A Sbjct: 33 KEALKEFRK----ALKARPNN-PEILHYNAITLLKLKRPEKALECYEKILKNNPKLAEAW 87 Query: 114 FHLGTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRL 173 + G L +GR+ EA+ +A+ + P+ A N L+ELG A E ++++ ++ Sbjct: 88 NNKGLVLKELGRYDEALECYEKALKINPKYAGAWNNKALVLKELGRYDEALECYEKALQI 147 Query: 174 RPEVAETWFN----------------------------------LGLTLQDMKEGAAAVD 199 P++A+ W+N G+TL ++K A+ Sbjct: 148 NPKLADAWYNKGSVLIYLKKYKKALKCFEKAIELNPKNYRAWGTKGITLHNLKIYEEALK 207 Query: 200 AFARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTALRLG 242 + + LQL P A N G+ E+ R D++L+ + AL++ Sbjct: 208 CYDKVLQLNPQDDKAWNNKGLVFNELGRYDESLECYEKALQIN 250 Score = 79.3 bits (194), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 52/221 (23%), Positives = 103/221 (46%) Query: 22 GRAAEAEQACHALLALVPQHPAAHQLLAMLALDRQALAQARQHILLSLAPRPQHVPSLLM 81 GR EA + L + P++ A A++ + +A + +L P+ + Sbjct: 98 GRYDEALECYEKALKINPKYAGAWNNKALVLKELGRYDEALECYEKALQINPKLADAWYN 157 Query: 82 AGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVALAP 141 G + + A++ F+ A P+ +A G +L + + EA+ + + L P Sbjct: 158 KGSVLIYLKKYKKALKCFEKAIELNPKNYRAWGTKGITLHNLKIYEEALKCYDKVLQLNP 217 Query: 142 QAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAF 201 Q +A N G ELG + E ++++ ++ P++AE W N G+ L ++ A++ + Sbjct: 218 QDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNKGVVLSELGRYEEALECY 277 Query: 202 ARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTALRLG 242 +AL++ P N G+ L+E+ + DAL+ F+ AL + Sbjct: 278 EKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEIN 318 Score = 73.9 bits (180), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 73/138 (52%) Query: 72 RPQHVPSLLMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVA 131 PQ + G + G +++ ++ A + P+L++A + G LS +GR+ EA+ Sbjct: 216 NPQDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNKGVVLSELGRYEEALE 275 Query: 132 ALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDM 191 +A+ + P+ + N G L ELG+ A E F+++ + PE A+ W G+ L+D+ Sbjct: 276 CYEKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEINPEFADAWKWKGIILEDL 335 Query: 192 KEGAAAVDAFARALQLRP 209 K+ ++ + +AL+L P Sbjct: 336 KKPEESLKCYKKALKLNP 353 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 39/134 (29%), Positives = 73/134 (54%), Gaps = 2/134 (1%) Query: 111 QAHFHLGTSLSAV--GRHAEAVAALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFK 168 +A +HL S++ G++ EA+ R+A+ P E + L +L A E ++ Sbjct: 15 KAGWHLAGGRSSLKQGKYKEALKEFRKALKARPNNPEILHYNAITLLKLKRPEKALECYE 74 Query: 169 QSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADAALNLGVALQEIHRM 228 + + P++AE W N GL L+++ A++ + +AL++ P YA A N + L+E+ R Sbjct: 75 KILKNNPKLAEAWNNKGLVLKELGRYDEALECYEKALKINPKYAGAWNNKALVLKELGRY 134 Query: 229 DDALQAFRTALRLG 242 D+AL+ + AL++ Sbjct: 135 DEALECYEKALQIN 148 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 45/163 (27%), Positives = 80/163 (49%) Query: 80 LMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVAL 139 L GR +L +G A++ F A + +P + + +L + R +A+ + + Sbjct: 20 LAGGRSSLKQGKYKEALKEFRKALKARPNNPEILHYNAITLLKLKRPEKALECYEKILKN 79 Query: 140 APQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVD 199 P+ EA N G L+ELG A E ++++ ++ P+ A W N L L+++ A++ Sbjct: 80 NPKLAEAWNNKGLVLKELGRYDEALECYEKALKINPKYAGAWNNKALVLKELGRYDEALE 139 Query: 200 AFARALQLRPGYADAALNLGVALQEIHRMDDALQAFRTALRLG 242 + +ALQ+ P ADA N G L + + AL+ F A+ L Sbjct: 140 CYEKALQINPKLADAWYNKGSVLIYLKKYKKALKCFEKAIELN 182 >MTH68 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus Length = 228 Score = 90.9 bits (224), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 86/148 (58%) Query: 95 AVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSAL 154 A++ +D + P+ +A + G + +GR+ E++ +A+ + P+ EA N G L Sbjct: 54 ALKCYDKVLQLNPQDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNKGVVL 113 Query: 155 RELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADA 214 ELG A E ++++ + PE +TW N GL L+++ + A++ F +AL++ P +ADA Sbjct: 114 SELGRYEEALECYEKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEINPEFADA 173 Query: 215 ALNLGVALQEIHRMDDALQAFRTALRLG 242 G+ L+++ + +++L+ ++ AL+L Sbjct: 174 WKWKGIILEDLKKPEESLKCYKKALKLN 201 Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 74/144 (51%) Query: 99 FDAAARHQPELSQAHFHLGTSLSAVGRHAEAVAALRQAVALAPQAMEAVLNLGSALRELG 158 F+ A P+ +A G +L + + EA+ + + L PQ +A N G ELG Sbjct: 24 FEKAIELNPKNYRAWGTKGITLHNLKIYEEALKCYDKVLQLNPQDDKAWNNKGLVFNELG 83 Query: 159 ELPAAREAFKQSCRLRPEVAETWFNLGLTLQDMKEGAAAVDAFARALQLRPGYADAALNL 218 + E ++++ ++ P++AE W N G+ L ++ A++ + +AL++ P N Sbjct: 84 RYDESLECYEKALQINPKLAEAWNNKGVVLSELGRYEEALECYEKALEIDPEDDKTWNNK 143 Query: 219 GVALQEIHRMDDALQAFRTALRLG 242 G+ L+E+ + DAL+ F+ AL + Sbjct: 144 GLVLEELGKYKDALECFQKALEIN 167 Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 73/138 (52%) Query: 72 RPQHVPSLLMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVGRHAEAVA 131 PQ + G + G +++ ++ A + P+L++A + G LS +GR+ EA+ Sbjct: 65 NPQDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNKGVVLSELGRYEEALE 124 Query: 132 ALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNLGLTLQDM 191 +A+ + P+ + N G L ELG+ A E F+++ + PE A+ W G+ L+D+ Sbjct: 125 CYEKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEINPEFADAWKWKGIILEDL 184 Query: 192 KEGAAAVDAFARALQLRP 209 K+ ++ + +AL+L P Sbjct: 185 KKPEESLKCYKKALKLNP 202 >mll2645 [R] COG0457 FOG Mlo Mesorhizobium loti Length = 592 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/214 (32%), Positives = 101/214 (47%) Query: 5 PAAPDQIMGAALQHYNAGRAAEAEQACHALLALVPQHPAAHQLLAMLALDRQALAQARQH 64 P DQ + ALQ + AGR EAE +LA P+H AA L +L + Sbjct: 42 PLGLDQYVQQALQLHQAGRRQEAESIYRQVLARQPKHAAAAHFLGLLLHQTGRSEEGLDL 101 Query: 65 ILLSLAPRPQHVPSLLMAGRIALAEGDPATAVQYFDAAARHQPELSQAHFHLGTSLSAVG 124 I S++ +P + L G + G A A+ +F A +PE A +LG+SL +G Sbjct: 102 IERSVSLQPTNADFLNNFGTVMRDLGRVAAAIDFFRGAVDLRPEQLAARDNLGSSLKQLG 161 Query: 125 RHAEAVAALRQAVALAPQAMEAVLNLGSALRELGELPAAREAFKQSCRLRPEVAETWFNL 184 R EA R VA P + A + L L+E G L A F++S +RP+ A+ L Sbjct: 162 RFEEAEDIYRGTVARNPFHVRARIGLAETLQEAGRLDEALAVFRESLTIRPKDADLLHGL 221 Query: 185 GLTLQDMKEGAAAVDAFARALQLRPGYADAALNL 218 G+ + + + A D F +AL + PG A A L L Sbjct: 222 GVGMMEKGKLDEAADLFRQALAVNPGMATAWLML 255