BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0018.p (319 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii 338 1e-92 CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetob... 209 8e-54 TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima 204 2e-52 BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis 194 2e-49 RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii 172 1e-42 >RP109 [C] COG0280 Phosphotransacetylase Rpr Rickettsia prowazekii Length = 351 Score = 338 bits (866), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 175/317 (55%), Positives = 232/317 (73%), Gaps = 7/317 (2%) Query: 3 PPTQATP------AERYGQLIRDALGAQAMRVAVVHPCSAEALQGALEAREEGLLEPLLV 56 PPT+ A+ + L+ A G + ++ AVVHP E+L GA+ A + +++P+L+ Sbjct: 26 PPTEIKDSDFDKAAKHFINLLLRADGLKPIKTAVVHPIDKESLLGAVRAAQFNVIKPILI 85 Query: 57 GPEARIRRVAEEAGLSLAGLQIESTEHSHAAAARAVELAVQGQVSALMKGSLHSDELLGA 116 GP+ +I VA+ + L Q+ + EHSH AA +AVELA + +V+A+MKG+LH+DEL+ A Sbjct: 86 GPQHKIESVAKVNDVDLENYQVINAEHSHEAAKKAVELAKKREVAAIMKGALHTDELMSA 145 Query: 117 VVASGSGLRTERRISHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMG 176 VV +GLRTERRISH + MA+ T+ KP IITDAAINI PTL KRDI QNAIDL+H++ Sbjct: 146 VVYKENGLRTERRISHAFLMAVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHIIK 205 Query: 177 VPRP-HVAVLAAVETVNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQSASI 235 + VAVL+AVETV A+P+TLDAAAL+ MA R QIT A+VDGPLAFDNAISL +A Sbjct: 206 EDKQVRVAVLSAVETVTSAIPTTLDAAALSKMADRGQITNAVVDGPLAFDNAISLFAAEA 265 Query: 236 KQITSPVAGSADILLVPDLEAGNMLAKQLIYLSQAEAAGLVLGARVPVILTSRADSLRVR 295 K I+SPV+G+ADIL+VPDLE+GNMLAKQL YL QA AG+VLGARVP+ILTSRAD + +R Sbjct: 266 KGISSPVSGNADILVVPDLESGNMLAKQLKYLGQAVMAGIVLGARVPIILTSRADPIDMR 325 Query: 296 LASSALARLFASRSKVQ 312 + S LA +++K + Sbjct: 326 VISCVLASFIYNQTKAK 342 >CAC3076 [C] COG0280 Phosphotransacetylase Cac Clostridium acetobutylicum Length = 301 Score = 209 bits (531), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 111/299 (37%), Positives = 172/299 (57%) Query: 11 ERYGQLIRDALGAQAMRVAVVHPCSAEALQGALEAREEGLLEPLLVGPEARIRRVAEEAG 70 + + ++I + +VAV L+ +A++ G+ + +LVG I +A + G Sbjct: 3 KSFNEIIMKVKSKEMKKVAVAVAQDEPVLEAVRDAKKNGIADAILVGDHDEIVSIALKIG 62 Query: 71 LSLAGLQIESTEHSHAAAARAVELAVQGQVSALMKGSLHSDELLGAVVASGSGLRTERRI 130 + + +I + + AA +AVEL G+ +MKG +++ L +V+ GLRT + + Sbjct: 63 MDVNDFEIVNEPNVKKAALKAVELVSTGKADMVMKGLVNTATFLRSVLNKEVGLRTGKTM 122 Query: 131 SHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAAVET 190 SHV + + L +TD A N P L K DI N++ + H +G+ P VA + AVE Sbjct: 123 SHVAVFETEKFDRLLFLTDVAFNTYPELKEKIDIVNNSVKVAHAIGIENPKVAPICAVEV 182 Query: 191 VNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQSASIKQITSPVAGSADILL 250 +NP MPSTLDAA L+ M+ R QI G +VDGPLA D A+S ++A K +T VAG ADI L Sbjct: 183 INPKMPSTLDAAMLSKMSDRGQIKGCVVDGPLALDIALSEEAAHHKGVTGEVAGKADIFL 242 Query: 251 VPDLEAGNMLAKQLIYLSQAEAAGLVLGARVPVILTSRADSLRVRLASSALARLFASRS 309 +P++E GN++ K L Y + ++ G+++G PV+LTSRADS ++ S ALA L A Sbjct: 243 MPNIETGNVMYKTLTYTTDSKNGGILVGTSAPVVLTSRADSHETKMNSIALAALVAGNK 301 >TM1130 [C] COG0280 Phosphotransacetylase Tma Thermotoga maritima Length = 294 Score = 204 bits (520), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 114/268 (42%), Positives = 166/268 (61%), Gaps = 1/268 (0%) Query: 39 LQGALEAREEGLLEPLLVGPEARIRRVAEEAGLSLAGLQIESTEHSHAAAARAVELAVQG 98 ++ A E + EP+L GPE I R+ EE QI A AVE +G Sbjct: 28 IEAVYRAWRERVCEPVLFGPEEEITRIIEELVPEWKNPQIIDCPPEEAGRL-AVEAVSKG 86 Query: 99 QVSALMKGSLHSDELLGAVVASGSGLRTERRISHVYAMAIPTYAKPLIITDAAINIAPTL 158 + LMKG + + +L+ + GLRT + ++ V M IP + +PLII+D + I+PTL Sbjct: 87 ECDFLMKGKIKTGDLMKIYLDERYGLRTGKTMAMVSVMEIPDFPRPLIISDPGMLISPTL 146 Query: 159 AHKRDICQNAIDLLHVMGVPRPHVAVLAAVETVNPAMPSTLDAAALTVMATRHQITGALV 218 K D+ ++ + + +VMG+ P VAV+ A+E VNP MP T++AA L+ M R QI G +V Sbjct: 147 EQKVDMIEHCVRVANVMGLETPKVAVVGAIEVVNPKMPITMEAAILSKMNQRGQIKGCIV 206 Query: 219 DGPLAFDNAISLQSASIKQITSPVAGSADILLVPDLEAGNMLAKQLIYLSQAEAAGLVLG 278 DGP A DN +S ++A K I SPVAG ADIL++PD+EA N+L K L++L++A++A +LG Sbjct: 207 DGPFALDNVVSEEAAKKKGIQSPVAGKADILILPDIEAANILYKALVFLAKAKSASTILG 266 Query: 279 ARVPVILTSRADSLRVRLASSALARLFA 306 +VPV+LTSRADS + S AL+ +FA Sbjct: 267 GKVPVVLTSRADSEETKFYSIALSAVFA 294 >BS_yqiS [C] COG0280 Phosphotransacetylase Bsu Bacillus subtilis Length = 299 Score = 194 bits (494), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 122/295 (41%), Positives = 171/295 (57%), Gaps = 16/295 (5%) Query: 17 IRDALGAQAMR----VAVVHPCSAEALQGALEAREEGLLEPLLVGPEARIRRVAEEAGLS 72 ++D +G ++ +AV H E ++ A E LL G ++ + S Sbjct: 3 LKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLLTGDSKKLNELTS----S 58 Query: 73 LAGLQIE-----STEHSHAAAARAVELAVQGQVSALMKGSLHSDELLGAVVASGSGLRTE 127 + G Q+E + E S A RAV LMKG++ + LL AV+ GLR+ Sbjct: 59 MQGHQVEIVHANTPEESAKLAVRAVH---HKTADVLMKGNVPTSVLLKAVLNRQEGLRSA 115 Query: 128 RRISHVYAMAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVMGVPRPHVAVLAA 187 +SHV IP + + + +TD+A+NIAP+L R I QNA+ + H +G P A LAA Sbjct: 116 SVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAVGNNMPKAAALAA 175 Query: 188 VETVNPAMPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQSASIKQITSPVAGSAD 247 VETVNP M +T++AAAL M R QI G +VDGPLA DNA+S +A+ K+I+ VAG+ D Sbjct: 176 VETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAAQKKISGDVAGNPD 235 Query: 248 ILLVPDLEAGNMLAKQLIYLSQAEAAGLVLGARVPVILTSRADSLRVRLASSALA 302 ILLVP +EAGN+L K LIY ++A A ++ GA+ P+ LTSRADS +L S ALA Sbjct: 236 ILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAENKLYSIALA 290 >RC0147 [C] COG0280 Phosphotransacetylase Rco Rickettsia conorii Length = 155 Score = 172 bits (435), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 90/136 (66%), Positives = 107/136 (78%), Gaps = 1/136 (0%) Query: 136 MAIPTYAKPLIITDAAINIAPTLAHKRDICQNAIDLLHVM-GVPRPHVAVLAAVETVNPA 194 M + T+ KP IITDAAINI PTL KRDI QNAIDL+H++ + VAVL+ VETV A Sbjct: 1 MVVATFPKPFIITDAAINIRPTLEDKRDIVQNAIDLMHMIREDTQVRVAVLSVVETVTSA 60 Query: 195 MPSTLDAAALTVMATRHQITGALVDGPLAFDNAISLQSASIKQITSPVAGSADILLVPDL 254 +P+TLDAAAL+ M R QIT A+VDGPLAFDNAISL +A K I+S V+G+ADIL+VPDL Sbjct: 61 IPTTLDAAALSQMVDRGQITNAIVDGPLAFDNAISLFAAEAKCISSSVSGNADILVVPDL 120 Query: 255 EAGNMLAKQLIYLSQA 270 E+GNMLAKQL YL QA Sbjct: 121 ESGNMLAKQLKYLGQA 136