BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0010.p (1047 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3676 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1045 0.0 RSc1654 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 972 0.0 SMb20345 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 878 0.0 mlr7298 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 869 0.0 mlr2404 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 863 0.0 >PA3676 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1025 Score = 1045 bits (2703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 545/1030 (52%), Positives = 727/1030 (70%), Gaps = 11/1030 (1%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLSAW LQ++ +V +++ L+ +G SYS+L QSEDPPFTFK MV+QT+WPGA+A +V Sbjct: 3 FNLSAWALQNRQIVLYLMILLGAVGALSYSKLGQSEDPPFTFKAMVVQTNWPGASAEEVA 62 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDVAA 126 Q+T+RI +KL ET D D + S+SR G SQ+ F ++ +S++P+ WYQ+RKK+ D+ A Sbjct: 63 RQVTERIEKKLMETGDYDRIVSFSRPGVSQVTFMAREDIHSSEIPELWYQIRKKISDIRA 122 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFTPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 TLPQ ++GP+FNDEFG Y NIYAL G GF A ++DYAD+L+ +L + V K++ G Sbjct: 123 TLPQSIQGPFFNDEFGTTYGNIYALTGKGFDYAVMKDYADRLQLQLQRIRNVGKVELIGL 182 Query: 187 RQERIYIDIGNTRMTRLGISPQQLADAIGGQNAVVPGGLITTSSDRVYVRPTGQFDNLRA 246 + E+I+ID+ NT++ LG+ + A+ QNAV G T+SDRV +R +G+FD++ Sbjct: 183 QDEKIWIDLSNTKLATLGLPLAAVQKALEEQNAVASSGFFETASDRVQLRVSGRFDSVEE 242 Query: 247 LEDKIIHVNNRNFRLGDIATITRGYDEPQEQEMRANGQPVLGIGVTMQPGGDVIRLGKAL 306 + D I V +R FR+GD+A + RG+++P MR G+ +G+ V M+PGGD++ LGKAL Sbjct: 243 IRDFPIRVGDRTFRIGDVAEVRRGFNDPPAPRMRFMGEDAIGLAVAMKPGGDILVLGKAL 302 Query: 307 DERTEQLRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 + +L++ LPAGL L VS P AV V +F+ +AEA+ IVL+VS SLG+RTG+V Sbjct: 303 ETEFARLQQSLPAGLELRKVSDQPAAVRTGVGEFIRVLAEALVIVLLVSFFSLGLRTGLV 362 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 V +SIP+VLA+T M+ F IGLHK+SLG LVLALGLLVDDAIIAVEMMAVK+EQG++R Sbjct: 363 VALSIPLVLAMTFAAMHYFGIGLHKISLGALVLALGLLVDDAIIAVEMMAVKMEQGYDRL 422 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 +AA+FA+TSTAFPMLTGTL+T AGFLPIA A+SGTGEYTRS+F+V IAL++SW AAVV Sbjct: 423 KAASFAWTSTAFPMLTGTLITAAGFLPIATAQSGTGEYTRSLFQVVTIALVVSWFAAVVF 482 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 +P LG +L + ++ A H G D P Y T Y RR V WCV +R Sbjct: 483 VPYLGAKLLPDLA------RLHAQKHGG--SADGYDP-YATAFYQRFRRLVEWCVRYRKT 533 Query: 547 VVIATTVLFIASLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T F+ +L F LVPQQFFP S R ELL+D+ L E AS +T E R+E +L+ Sbjct: 534 VIVLTLAAFVGALLLFRLVPQQFFPPSARLELLLDIKLAEGASLRSTGEEVQRLEKMLQG 593 Query: 607 RPQIDHVVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRKQFS 666 ID+ V++VG G+PRFYLPLDQQL + +FAQ VV AK +E REAL + L E + + F Sbjct: 594 HDGIDNYVAYVGTGSPRFYLPLDQQLPAASFAQVVVLAKDLESREALRKWLIERMNEDFP 653 Query: 667 GARTRMTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAELRKESRATNIQFDWDEPAQ 726 R+R++RLENGPPVG+PVQFR+SGE IP+VR +A +VA ++R+ N+ DW+EP+ Sbjct: 654 HLRSRISRLENGPPVGYPVQFRVSGEDIPQVRELARKVADKMRENPHVVNVHLDWEEPS- 712 Query: 727 RSVSFEIDQKRAGELGLSSQQIANFLAMQLSGFTVTQYRERDKLIGVDLRAPRSERVDPS 786 + V IDQ+RA LG+S+ ++ FL L+G V+ +RE ++LI + LR ER D S Sbjct: 713 KVVYLSIDQERARALGVSTASLSQFLQSALTGSHVSFFREDNELIEILLRGTEQERRDLS 772 Query: 787 RLATLSMPTANG-PVPLAALGQFHNTLEYGVIWERDRQPTITVLADVRAGVQGIDVTNDV 845 L +L++PT NG V L+ + E G+IW R+R PT+TV AD+ + + Sbjct: 773 LLPSLAVPTENGRSVALSQIATLEYGFEEGIIWHRNRLPTVTVRADIYDDSLPATLVAQI 832 Query: 846 NRKLDALRGELPVGYRIDVGGPVEENAKAQSSISAQMPLMIIAVLLLLMVQLQSFGRTLM 905 L+ +R ELP GY ++VGG VE+ AK QSS++A +PL I+ VL LLMVQL+SF R M Sbjct: 833 APTLEPIRAELPDGYLLEVGGTVEDAAKGQSSVNAGVPLFIVVVLSLLMVQLRSFSRMAM 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V +TAPLGLIGV LLLF QPFGFVAMLGTIA+ G+IMRNSVILVDQIEQDI+ G R+ Sbjct: 893 VFLTAPLGLIGVTLFLLLFRQPFGFVAMLGTIALAGMIMRNSVILVDQIEQDISHGLDRW 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 AI+ ATVRRFRPI LTA AAVLA+IPL RS FFGPMA A+MGG+ +AT+LTL +LPALY Sbjct: 953 HAIIEATVRRFRPIVLTALAAVLAMIPLSRSVFFGPMAVAIMGGLIVATVLTLLFLPALY 1012 Query: 1026 ALCYRVKPDE 1035 A +RVK DE Sbjct: 1013 AAWFRVKKDE 1022 >RSc1654 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1039 Score = 972 bits (2513), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/1040 (49%), Positives = 681/1040 (65%), Gaps = 29/1040 (2%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 RFNLS W L+HQ L F+L + L GI +Y++L Q EDPPFTF+ MV+Q WPGATA Q+ Sbjct: 5 RFNLSRWALEHQPLTRFLLVALLLGGIFAYTQLGQDEDPPFTFRAMVVQAFWPGATAEQM 64 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDVA 125 Q+TD+I + LQE P +RSYS+ G++ + F + DT+P Q WY VRKKVGD+A Sbjct: 65 SRQVTDKIEKALQEVPYAWKIRSYSKPGETLVTFQLADTSPTKDTQQLWYTVRKKVGDIA 124 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFTPAQLRDYADQLRGELLHVPGVAKIDYFG 185 ++LP GV+GPYFND+FGDVY +IYAL+ DGFT QL DYAD +R +LL VP VAK+ G Sbjct: 125 SSLPTGVRGPYFNDDFGDVYGSIYALSADGFTYRQLNDYADAIRQQLLRVPNVAKVTLLG 184 Query: 186 ERQERIYIDIGNTRMTRLGISPQQLADAIGGQNAVVPGGLITTSSDRVYVRPTGQFDNLR 245 ++ E+IYI+ + ++G+ +A+ I QN + P G++ T +D V +R +GQF ++R Sbjct: 185 DQDEKIYIEFQQAKFAQMGLDINSIANQIAQQNNIGPSGVLVTPTDNVQIRLSGQFSDIR 244 Query: 246 ALEDKIIH--VNNRNFRLGDIATITRGYDEPQEQEMRANGQPVLGIGVTMQPGGDVIRLG 303 LE+ + N RLGDIATI GY +P +MR NG+ V+G+G++M GGD+I+LG Sbjct: 245 DLENLTLRGPGGTSNIRLGDIATIRHGYIDPPRAKMRFNGKEVIGLGISMAKGGDIIQLG 304 Query: 304 KALDERTEQLRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRT 363 K L E++R +LP G+ + V P +V+ SV +F+ + EAV IVL VS +SLG+ T Sbjct: 305 KDLRATVERIRAKLPVGIEMQQVQDQPQSVQHSVGEFVHVLIEAVVIVLAVSFLSLGLHT 364 Query: 364 ----------GMVVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVE 413 G+VV ++IP+VLAVT LFM +FDIGLHK+SLG L++ALGLLVDDAIIAVE Sbjct: 365 KPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKISLGALIIALGLLVDDAIIAVE 424 Query: 414 MMAVKLEQGWNRRRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSA 473 MM KLE+G+++ AA FAYTSTA PMLTGTL+T GFLP+ LA+S GEYT IF V+A Sbjct: 425 MMVRKLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFLPVGLARSTVGEYTFGIFAVTA 484 Query: 474 IALLLSWLAAVVLIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWL 533 +AL+LSW+AAVV +P LGY +L K H + H ++ T Y Sbjct: 485 LALVLSWVAAVVFVPYLGYLLLHTK---------------SHVGDGGHHELFDTPFYNRF 529 Query: 534 RRSVAWCVAFRGRVVIATTVLFIASLAAFALVPQQFFPSSDRPELLIDLHLPERASFEAT 593 R V WCV +R V++ T F+ + F V +QFFP S RPEL+++L LPE ASF T Sbjct: 530 RGWVNWCVEYRKTVIVITLAAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEGASFGQT 589 Query: 594 QREAVRMEALLKDRPQIDHVVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREAL 653 + EA R EAL++ + ++ V F+G GAPRFYLPLDQ L N AQ +V S+E RE + Sbjct: 590 EAEAKRFEALIRQQKSVESVAFFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSLETREDV 649 Query: 654 ARALEEPLRKQFSGARTRMTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAELRKESR 713 + + L+ QF R R+ L NGPPV +PVQFR+ G I VR IA+QV A ++ Sbjct: 650 RQEIIGLLKSQFPQLRGRVKLLPNGPPVPYPVQFRVMGPDIGGVRKIADQVKAIMQANPN 709 Query: 714 ATNIQFDWDEPAQRSVSFEIDQKRAGELGLSSQQIANFLAMQLSGFTVTQYRERDKLIGV 773 + +W+E + + +IDQ +A LG+++ IA +SG + QYR+ DKL+ + Sbjct: 710 TVGVNDNWNENV-KLLRLDIDQDKARALGVTTGSIAQVTQTVMSGAPIAQYRDGDKLLDI 768 Query: 774 DLRAPRSERVDPSRLATLSMPTANGP-VPLAALGQFHNTLEYGVIWERDRQPTITVLADV 832 +R ER L + +PTA+G VPL + + E GVIW +R ITV +DV Sbjct: 769 VMRPQERERNTLDALQNVQVPTASGRVVPLTQVARVGFAWEPGVIWRENRDYGITVQSDV 828 Query: 833 RAGVQGIDVTNDVNRKLDALRGELPVGYRIDVGGPVEENAKAQSSISAQMPLMIIAVLLL 892 GVQG VT +N LD +R +LP Y+I + G EE+A A +SI AQMPL I + L Sbjct: 829 VDGVQGPTVTAQINPLLDKIRADLPPDYQIKIAGAEEESANAGASIVAQMPLCIFIIFTL 888 Query: 893 LMVQLQSFGRTLMVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVD 952 LM+QL SF R++MV +T PLGLIG LLL P GFVA LG A++G+I+RNSVILVD Sbjct: 889 LMLQLHSFSRSVMVFLTGPLGLIGAAATLLLLRAPMGFVAQLGITALIGMIIRNSVILVD 948 Query: 953 QIEQDIAAGRGRFDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITI 1012 QIEQD+A G + AIV A VRRFRPI LTAAAAVLA+IPL RS F+GPMA A+MGG+ + Sbjct: 949 QIEQDVATGVPTWTAIVEAAVRRFRPIILTAAAAVLAMIPLSRSVFWGPMAAAIMGGLIV 1008 Query: 1013 ATILTLFYLPALYALCYRVK 1032 AT+LTL +LPALYA +RVK Sbjct: 1009 ATVLTLLFLPALYAAWFRVK 1028 >SMb20345 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1049 Score = 878 bits (2269), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/1049 (43%), Positives = 668/1049 (63%), Gaps = 26/1049 (2%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W + H ++ F+LAL+ + G R+ Q EDP FTF+VMV+Q WPGA+ ++++ Sbjct: 11 FNLSRWAIGHPSIARFLLALIIITGGLGLLRMGQREDPEFTFRVMVVQAVWPGASIQEME 70 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDVAA 126 +Q+ ++I RKLQETP +DF+RSY+RAG + + I+ A +V +YQVRKKVGD+A Sbjct: 71 DQVVNKIERKLQETPHLDFVRSYTRAGSAIITVQIEGDTNADEVADAFYQVRKKVGDIAN 130 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFTPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 LP+GV GPYFNDEFGD + +++++GDGF+ +L+ +A + R LL PGV K+ G+ Sbjct: 131 ELPEGVLGPYFNDEFGDTFITLHSISGDGFSYPELKRFAIEGRDMLLATPGVEKVVVLGD 190 Query: 187 RQERIYIDIGNTRMTRLGISPQQLADAIGGQNAVVPGGLITTSSDRVYVRPTGQFDNLRA 246 + E+IYID+ + + G++ L +AI GQN V G + T + V + G + Sbjct: 191 QPEKIYIDLSSKVLAERGLTFNDLRNAIAGQNNVDYAGSVDTGTRSVRISVEGDVTKVED 250 Query: 247 LEDKIIHVNNRNFRLGDIATITRGYDEPQEQEMRANGQPVLGIGVTMQPGGDVIRLGKAL 306 + + + +R RLGDIAT+T G ++P ++ R NG + IGV M G +V +GKA+ Sbjct: 251 IRELRLRAGDRTIRLGDIATVTSGLEDPYARKFRFNGHDSVQIGVVMAKGFNVTDVGKAV 310 Query: 307 DERTEQLRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 + ++ LP G+++ VS+ P V +++ +F A+ EA+ IVL+VS +S+G R+G+V Sbjct: 311 EATYDRFESALPYGVSVDQVSNQPEVVTEAITEFSHALIEALIIVLIVSFLSIGWRSGLV 370 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 + I+IP+VLA T MY I L ++SLG L++ALGLLVDDA+I VEMM KLE+G + Sbjct: 371 IAIAIPLVLAATFAIMYELGIDLQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLEKI 430 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 AA+FAY+STAFPMLTGTL+T AGF+P+ A+S GEY RS+F V IAL++SW AV Sbjct: 431 DAASFAYSSTAFPMLTGTLITTAGFIPVGFAESTAGEYVRSLFYVVGIALVVSWFVAVYF 490 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 P LGY +LK++ HAG H ++ TR Y LR +V W V R Sbjct: 491 TPWLGYMILKQR------------HHAG-----THHDVFDTRFYRRLRTTVGWAVRHRVV 533 Query: 547 VVIATTVLFIASLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T +F+ SL AF +P+ FFP S RPE+L+DL LPE S + +++A +E + D Sbjct: 534 VLLMTLAIFVTSLWAFQFIPKNFFPQSSRPEILVDLWLPEGTSIKEVEKQAKALEERMMD 593 Query: 607 RPQIDHVVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRKQFS 666 + +++G GAPRF+LPLDQQL +PNFAQ +V AK RE L L L + F Sbjct: 594 DEDKRFIATYIGEGAPRFFLPLDQQLRNPNFAQLLVMAKDEPARERLIAKLRTILAEDFP 653 Query: 667 GARTRMTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAELRKESRATNIQFDWDEPAQ 726 R ++ RL GPP G+PVQ R+ G +VR IA+QV + ++ I DW EP Sbjct: 654 SIRAKVDRLFLGPPTGWPVQMRVMGPDREEVRRIADQVKTKFQENPMLGAIHDDWLEPVP 713 Query: 727 RSVSFEIDQKRAGELGLSSQQIANFLAMQLSGFTVTQYRERDKLIGVDLRAPRSERVDPS 786 ++ IDQ RA LG++SQ+I L +SG + +R+ ++ + + R P R S Sbjct: 714 -AMKLVIDQDRARALGITSQRIRQMLQAAMSGVPLDSFRDGEETVSIMAREPGGNRHLLS 772 Query: 787 RLATLSMPTA-NGPVPLAALGQFHNTLEYGVIWERDRQPTITVLADVRAGVQGIDVTNDV 845 + ++ +PT G VP++ + + +E G+ W RDR PTITV + GVQ DV + Sbjct: 773 AVQSVYVPTDFGGFVPVSQIAKVVPVMEQGIEWRRDRLPTITVRGTLPDGVQPNDVAMQL 832 Query: 846 NRKLDALRGELPVGYRIDVGGPVEENAKAQSSISAQMPLMIIAVLLLLMVQLQSFGRTLM 905 +L LR L GY++++ G E++A++Q+SI+A+ P+M++ +++LLMVQLQ FG+ ++ Sbjct: 833 FDELKGLRDGLAPGYKVEIQGGAEDSAESQASIAAKAPIMLVVIVILLMVQLQHFGKAML 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V+ T PLG+IG ALL+ G PFGFVA+LG IA+LGII+RNS+ILVDQI+QDIAAG R Sbjct: 893 VLATGPLGIIGAAAALLISGAPFGFVAILGVIALLGIIIRNSIILVDQIDQDIAAGMERS 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 +AI+GA VRRFRPI LTA AVLALIP+ R F+GP+A A+MGGI +AT+LT+ LPA Y Sbjct: 953 EAIIGAAVRRFRPIILTALTAVLALIPISRGVFWGPLAYAMMGGILVATVLTILVLPAGY 1012 Query: 1026 ALCY-------RVKPDETHHRDHAAQGSH 1047 AL + + P+ +D+A + H Sbjct: 1013 ALFFGKEPKSRKTDPEPLAAQDNADEQEH 1041 >mlr7298 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1046 Score = 869 bits (2246), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/1039 (43%), Positives = 662/1039 (63%), Gaps = 19/1039 (1%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W + H ++ F+ L+ + G R+ Q EDP FTF+VMV+Q WPG++ ++++ Sbjct: 11 FNLSRWAIGHPSIARFLFGLIIIAGALGLMRMGQKEDPDFTFRVMVVQAIWPGSSIQEME 70 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDVAA 126 +Q+ ++I RKLQETP +DF+RS++RAG + + IK A++V +YQVRKKVGD++ Sbjct: 71 DQVVNKIERKLQETPHLDFVRSFTRAGSAIITVQIKGDTNAAEVADAFYQVRKKVGDISG 130 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFTPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 LPQG+ GPYFNDEFGD + +++++GDGF+ +L+ +A Q R LL PGV K G+ Sbjct: 131 DLPQGLLGPYFNDEFGDTFITLHSISGDGFSYPELKKFAIQARDMLLTTPGVEKAVIIGD 190 Query: 187 RQERIYIDIGNTRMTRLGISPQQLADAIGGQNAVVPGGLITTSSDRVYVRPTGQFDNLRA 246 + E++YID+ + + G++ L +AI GQN V P G + T + V + G Sbjct: 191 QPEKLYIDVSSKALAERGLTLPDLQNAIKGQNNVDPAGAVDTGVNSVRISVEGDVTKAAD 250 Query: 247 LEDKIIHVNNRNFRLGDIATITRGYDEPQEQEMRANGQPVLGIGVTMQPGGDVIRLGKAL 306 + + + + RLGDIAT+T G ++P +++ R NG + +GV M G V +GK + Sbjct: 251 IRELRLRAGGQVTRLGDIATVTSGLEDPFQRKYRFNGHDSVQLGVVMAKGFKVTDVGKDV 310 Query: 307 DERTEQLRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 + ++ + LP G+++ +S P V +V +F+ A+ EA+ IVLVVS +S+G R+G+V Sbjct: 311 EATYKRFEEALPYGVSVDQISDQPGVVTDAVAEFMHALGEALLIVLVVSFLSIGWRSGLV 370 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 + I+IP+VLA T MY I L ++SLG L++ALGLLVDDA+I VEMM KLE+G + Sbjct: 371 IAIAIPLVLAATFAIMYELGIDLQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLVKI 430 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 AA+FAYTSTAFPML+GTL+T AGF+P+ A S GEY R++F V IAL++SW AV Sbjct: 431 EAASFAYTSTAFPMLSGTLITTAGFIPVGFAASTAGEYVRTLFYVVGIALIVSWFVAVYF 490 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 P LG +LK++ HAG H ++ TR Y LR +V W V R Sbjct: 491 TPWLGNMILKQR------------KHAG-----THHDVFDTRFYRRLRATVGWAVRHRII 533 Query: 547 VVIATTVLFIASLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T V F SL AF +PQ FFP S RPE+L+DL LPE S + + +A +EA + D Sbjct: 534 VLVMTLVTFGTSLWAFQFIPQNFFPQSSRPEILVDLWLPEGTSIKEVETQAKALEAKMMD 593 Query: 607 RPQIDHVVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRKQFS 666 + +++G GAPRF+LPLDQQL +PNFAQ +V A RE L L L + F Sbjct: 594 DKDKRFIATYIGEGAPRFFLPLDQQLRNPNFAQMLVMANDEPARERLIVKLRTVLAEDFP 653 Query: 667 GARTRMTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAELRKESRATNIQFDWDEPAQ 726 R ++ RL GPP G+PVQ R+ G +VR IA+QV A+ R++ + DW EP Sbjct: 654 SIRAKVDRLFLGPPTGWPVQMRVMGPDRQEVRRIADQVKAKFREDPLLGAVHDDWLEPVP 713 Query: 727 RSVSFEIDQKRAGELGLSSQQIANFLAMQLSGFTVTQYRERDKLIGVDLRAPRSERVDPS 786 ++ IDQ RA LG++SQ+I L ++G + +R+ ++ + + R P + R S Sbjct: 714 -AMKLVIDQDRARALGVTSQRIRQMLQATMAGAPLDDFRDGEETVSIVAREPDASRSLLS 772 Query: 787 RLATLSMPTA-NGPVPLAALGQFHNTLEYGVIWERDRQPTITVLADVRAGVQGIDVTNDV 845 + ++ +PT G VPL+ + + LE G+ W RDR PTI+V A + GVQ DV + Sbjct: 773 SVDSVYVPTDFGGFVPLSQVAKVVPVLEQGIEWRRDRLPTISVRATLPDGVQSNDVVTKM 832 Query: 846 NRKLDALRGELPVGYRIDVGGPVEENAKAQSSISAQMPLMIIAVLLLLMVQLQSFGRTLM 905 + + LR L GY+I++ G E++A++Q+SI+A+ P+M+ +++LLM+QLQ+FG+ ++ Sbjct: 833 YKDMQGLRDGLAPGYKIEIQGGAEDSAESQASIAAKAPIMLAIIVVLLMIQLQNFGKAML 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V+ T PLG+IG ALL+ G PFGFVA+LG IA+LGIIMRNS+ILVDQI+QDIA G R Sbjct: 893 VLATGPLGIIGAAAALLISGAPFGFVAILGVIALLGIIMRNSIILVDQIDQDIARGMERS 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 +AI+G+ VRRFRPI LTA AVLALIP+ R+ F+GP+A A+MGGI +AT+LT+ LPA Y Sbjct: 953 EAIIGSAVRRFRPIVLTAMTAVLALIPISRAVFWGPLAYAMMGGIVVATVLTILVLPAGY 1012 Query: 1026 ALCYRVKPDETHHRDHAAQ 1044 AL + +P + + + A + Sbjct: 1013 ALFFGREPKKVVNSEQAPE 1031 >mlr2404 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1034 Score = 863 bits (2231), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/1033 (43%), Positives = 638/1033 (61%), Gaps = 21/1033 (2%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 RFNLS W + ++ALV F++ + + G+ +Y RL + EDP FT + MV+Q +WPGAT Sbjct: 4 RFNLSEWAVHNRALVVFLMLICVIGGVSAYERLGRQEDPDFTVQTMVVQANWPGATTADT 63 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDVA 125 +Q+TDRI +KL+ETP++D+++SY++ GQ+ +F +K++ P + WYQVRKKV D+ Sbjct: 64 LKQVTDRIEKKLEETPNLDYIKSYTKPGQATIFVYLKESTPKRDLSDIWYQVRKKVSDIG 123 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFTPAQLRDYADQLRGELLHVPGVAKIDYFG 185 TLPQGV GP+FNDEFGDV+ +Y + DGF+ + RD+A+ RGE L P V K+D +G Sbjct: 124 PTLPQGVVGPFFNDEFGDVFGTVYGITYDGFSAREARDFAETARGEFLRAPDVGKVDIYG 183 Query: 186 ERQERIYIDIGNTRMTRLGISPQQLADAIGGQNAVVPGGLITTSSDRVYVRPTGQFDNLR 245 ++ E++Y++ ++ L ++ + AI QNAV P G+I T + + V TG + Sbjct: 184 DQDEKVYLNFSPQKLANLKLNLDDVLAAIARQNAVAPSGIINTPQENMLVDVTGSLLSSD 243 Query: 246 ALEDKIIHVNNRNFRLGDIATITRGYDEPQEQEMRANGQPVLGIGVTMQPGGDVIRLGKA 305 + + + ++ R ++L DIA + RGY +P + R NG+P +GIGV M+ GG+ + GK Sbjct: 244 GIANLNLWIDGRFYKLTDIAQVQRGYSDPPSKMFRINGKPAIGIGVNMREGGNNLDFGKG 303 Query: 306 LDERTEQLRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGM 365 L E E+L++R P G+ L VS P V +++ F EA+ EA+ IVLVVS +SLG R G+ Sbjct: 304 LHEAAERLKQRFPVGIELNLVSDQPEVVHEAIGGFTEALVEAIVIVLVVSFLSLGFRAGL 363 Query: 366 VVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNR 425 VV +SIP+VLA+ + M I L ++SLG L++ALGLLVDDA+I +EMM K+E+G + Sbjct: 364 VVALSIPLVLAIVFVAMDALGISLQRISLGALIIALGLLVDDAMITIEMMISKIEEGMEK 423 Query: 426 RRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVV 485 +AA FAYTSTAFPMLTGTL+T+ GFLPI A S TG+Y S+F V A+AL+ SW AVV Sbjct: 424 IKAATFAYTSTAFPMLTGTLITILGFLPIGFANSNTGQYCFSLFVVIAVALVASWFVAVV 483 Query: 486 LIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRG 545 P++G +L P Q A P R R + + + R Sbjct: 484 FAPVIGLSIL---PSHTKKAQANAEPG---------------RFMRAFERLLGFAMRHRW 525 Query: 546 RVVIATTVLFIASLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLK 605 + A +LF ASL V QQFFP+S+RPELL+ + LP+ AS ATQ + R+E L Sbjct: 526 PTIAAALILFSASLYGMGFVQQQFFPTSNRPELLVTMTLPKNASIAATQAQTERLEKALA 585 Query: 606 DRPQIDHVVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRKQF 665 P I S+VG GA RFYLPLD QL + A+ VV K ++ R+ + LE F Sbjct: 586 GDPDIARFSSYVGGGAIRFYLPLDVQLDNDFMAETVVVTKDLKARDRVQARLETLFAGSF 645 Query: 666 SGARTRMTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAELRKESRATNIQFDWDEPA 725 R++RLE GPPVG+PVQ+R+S + R AEQVA LR N+ +DW E Sbjct: 646 PDVAVRISRLELGPPVGWPVQYRVSAPTTEEARQYAEQVAQTLRASGLVRNVNYDWAE-K 704 Query: 726 QRSVSFEIDQKRAGELGLSSQQIANFLAMQLSGFTVTQYRERDKLIGVDLRAPRSERVDP 785 +++ +DQ R + GLSS+++A L +SG TVTQ R+ L+ V RA ER Sbjct: 705 NKALRIVVDQDRVRQAGLSSEELAQALNRVISGSTVTQIRDSIYLVDVVARAESDERSSV 764 Query: 786 SRLATLSMPTANG-PVPLAALGQFHNTLEYGVIWERDRQPTITVLADVRAGVQGIDVTND 844 L L + T G VPL L QF L+ G +W R R PTITV A+ G+Q V Sbjct: 765 EALRNLQITTPTGASVPLRELAQFQYDLDDGYVWRRGRLPTITVQAEPLPGLQPASVHGR 824 Query: 845 VNRKLDALRGELPVGYRIDVGGPVEENAKAQSSISAQMPLMIIAVLLLLMVQLQSFGRTL 904 + ++ LR +P G ++ GG VE++A++ +++ AQ PLMI +L +LMVQL SF + Sbjct: 825 IAGAIEGLRKSMPAGTLLETGGTVEKSAQSNAALLAQFPLMITLMLTVLMVQLGSFRQLA 884 Query: 905 MVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGR 964 MV+ APLGLIGV ALL P GF+A LG IA+ G+I+RNSVILV QIE + A G Sbjct: 885 MVISVAPLGLIGVAAALLTTNTPMGFIATLGIIALAGMIIRNSVILVHQIEHERAQGIEP 944 Query: 965 FDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPAL 1024 + A++ AT RFRPI LTAAAA+L +IP++ F+GPMA A++GG+ +AT+LTL +LPAL Sbjct: 945 WKAVIDATTHRFRPIMLTAAAAILGMIPIMHDVFWGPMAFAIVGGLAVATVLTLVFLPAL 1004 Query: 1025 YALCYRVK-PDET 1036 Y ++ DET Sbjct: 1005 YVAVNGIREKDET 1017