BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0016.0026.p         (431 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0574 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxami...   256   1e-67
PM0815 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamid...   215   2e-55
NMB0757 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxami...   213   6e-55
NMA0968 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxami...   213   1e-54
HI1726 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamid...   199   1e-50

>RSc0574 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Rso Ralstonia solanacearum
          Length = 302

 Score =  256 bits (653), Expect = 1e-67,   Method: Compositional matrix adjust.
 Identities = 122/163 (74%), Positives = 138/163 (84%), Gaps = 4/163 (2%)

Query: 272 FEQASKLEQPIFTPAAKADLGEHDENISFEETEKRIGTELAHKIRDVAIQLYKEAADYAA 331
              A KL +PIFTPAAKAD+GEHDENISF+E E+RIG ELA +IRDV+I+LYKEA+D+AA
Sbjct: 140 LRNAEKLPEPIFTPAAKADVGEHDENISFDEVERRIGPELAAQIRDVSIRLYKEASDFAA 199

Query: 332 TRGIIIADTKFEFGLDDNGVLHLMDEVLTADSSRFWPADSYQVGISPPSFDKQFVRDYLE 391
           TRGIIIADTKFEFGLD+NG L LMDE LTADSSRFWPADSYQVG +PPSFDKQFVRD+LE
Sbjct: 200 TRGIIIADTKFEFGLDENGTLTLMDEALTADSSRFWPADSYQVGTNPPSFDKQFVRDWLE 259

Query: 392 TV----EGWQKTPPAPALPAEVIEKTGAKYREALERLTGEKLK 430
            V    + W KT PAP LPA++IEKT  KYREAL RLTGE L+
Sbjct: 260 AVRIDGQPWPKTAPAPQLPADIIEKTADKYREALTRLTGETLR 302


>PM0815 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Pmu Pasteurella multocida
          Length = 286

 Score =  215 bits (547), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 106/175 (60%), Positives = 134/175 (76%), Gaps = 6/175 (3%)

Query: 251 DVNASGLIQTLKSNLAISEARFEQASKLEQPIFTPAAKADLGEHDENISFEETEKRIGTE 310
           D   +G I      LA+ E   E ASKL +PIFTP++KA++G+HD NIS+ E E+ IG E
Sbjct: 117 DYQKTGTI----CGLALPEGLVE-ASKLPEPIFTPSSKAEVGDHDVNISYAECEQLIGPE 171

Query: 311 LAHKIRDVAIQLYKEAADYAATRGIIIADTKFEFGLDDNGVLHLMDEVLTADSSRFWPAD 370
           LA ++++ AI LY+ AA+YA ++GIII DTKFEFGLD+NG L LMDEVLT DSSRFW  +
Sbjct: 172 LAAQVKEKAIALYQAAAEYALSKGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWSVE 231

Query: 371 SYQVGISPPSFDKQFVRDYLETVEGWQKTPPAPALPAEVIEKTGAKYREALERLT 425
           +Y+ GI+PPSFDKQF+RD+LET  GW K PPAP +PAEVIEKT  KY+EAL+ LT
Sbjct: 232 TYREGINPPSFDKQFIRDWLET-SGWNKQPPAPKVPAEVIEKTVNKYQEALDLLT 285


>NMB0757 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Nme Neisseria meningitidis MC58
          Length = 287

 Score =  213 bits (543), Expect = 6e-55,   Method: Compositional matrix adjust.
 Identities = 101/154 (65%), Positives = 122/154 (79%), Gaps = 1/154 (0%)

Query: 272 FEQASKLEQPIFTPAAKADLGEHDENISFEETEKRIGTELAHKIRDVAIQLYKEAADYAA 331
            ++A +L + IFTP+ KA +G+HDENISFEE  + IG ELA ++R  A++LY EAA+YA 
Sbjct: 133 MQEAQQLPEVIFTPSTKAAVGDHDENISFEECGRIIGKELAEEVRAKAVRLYTEAAEYAK 192

Query: 332 TRGIIIADTKFEFGLDDNGVLHLMDEVLTADSSRFWPADSYQVGISPPSFDKQFVRDYLE 391
           +RGIII DTKFEFGLD+NG L LMDEVLT DSSRFWPAD Y+VG +PPSFDKQFVRD+LE
Sbjct: 193 SRGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWPADQYKVGTNPPSFDKQFVRDWLE 252

Query: 392 TVEGWQKTPPAPALPAEVIEKTGAKYREALERLT 425
              GW K  PAP +PA+VI+KT  KYREAL  LT
Sbjct: 253 Q-SGWNKKAPAPKVPADVIQKTVEKYREALTLLT 285


>NMA0968 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase NmA Neisseria meningitidis Z2491
          Length = 287

 Score =  213 bits (541), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 101/154 (65%), Positives = 121/154 (78%), Gaps = 1/154 (0%)

Query: 272 FEQASKLEQPIFTPAAKADLGEHDENISFEETEKRIGTELAHKIRDVAIQLYKEAADYAA 331
            ++A +L + IFTP+ KA +G+HDENISFEE  + IG ELA ++R  A++LY EAA+YA 
Sbjct: 133 MQEAQQLPEVIFTPSTKAAVGDHDENISFEECGRIIGKELAEEVRAKAVRLYTEAAEYAK 192

Query: 332 TRGIIIADTKFEFGLDDNGVLHLMDEVLTADSSRFWPADSYQVGISPPSFDKQFVRDYLE 391
           +RGIII DTKFEFGLD NG L LMDEVLT DSSRFWPAD Y+VG +PPSFDKQFVRD+LE
Sbjct: 193 SRGIIICDTKFEFGLDTNGTLTLMDEVLTPDSSRFWPADQYEVGTNPPSFDKQFVRDWLE 252

Query: 392 TVEGWQKTPPAPALPAEVIEKTGAKYREALERLT 425
              GW K  PAP +PA+VI+KT  KYREAL  LT
Sbjct: 253 Q-SGWNKKAPAPKVPADVIQKTVEKYREALTLLT 285


>HI1726 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase Hin Haemophilus influenzae
          Length = 306

 Score =  199 bits (506), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 100/175 (57%), Positives = 124/175 (70%), Gaps = 6/175 (3%)

Query: 251 DVNASGLIQTLKSNLAISEARFEQASKLEQPIFTPAAKADLGEHDENISFEETEKRIGTE 310
           D   +G I  LK    + EA     SKL + IFTP++K ++G HD NIS+ E EK IG +
Sbjct: 137 DYKQTGTICGLKLPEGLVEA-----SKLPEAIFTPSSKEEVGNHDINISYAECEKLIGAD 191

Query: 311 LAHKIRDVAIQLYKEAADYAATRGIIIADTKFEFGLDDNGVLHLMDEVLTADSSRFWPAD 370
           LA ++++ AI LY  AA+YA T+GIII DTKFEFGLD+NG L LMDEVLT DSSRFW  D
Sbjct: 192 LAAQVKEKAIALYTVAAEYALTKGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWSVD 251

Query: 371 SYQVGISPPSFDKQFVRDYLETVEGWQKTPPAPALPAEVIEKTGAKYREALERLT 425
           +YQ G +PPSFDKQFVRD+LE   GW K  PAP +P  +I+KT  KY+EAL+ LT
Sbjct: 252 TYQAGTNPPSFDKQFVRDWLEN-SGWNKQAPAPKVPENIIQKTVDKYQEALDLLT 305