BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0523.p (1372 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudo... 345 6e-94 NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neiss... 117 2e-25 NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neiss... 111 1e-23 XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 102 7e-21 XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylell... 100 2e-20 >PA3535_1 [O] COG1404 Subtilisin-like serine proteases Pae Pseudomonas aeruginosa Length = 453 Score = 345 bits (884), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 184/399 (46%), Positives = 254/399 (63%), Gaps = 22/399 (5%) Query: 61 ASWTGNKEFQTDWGLGAMNAQYAYAAGFSGLGIKLGAVDSGLLLSHAEFVTRNVKAVAVT 120 ASW + E+Q DWGL M A AYAAG G G+K+G +DSG SH + + V + Sbjct: 42 ASWR-SAEYQQDWGLERMRADQAYAAGIDGQGVKIGEMDSGFDPSHPDTPASRYQPVTAS 100 Query: 121 GTYANDGSQYQDGSQAWKAGDAFSTTGALSKLNDKHGSHVSGTIAAAKNGAGIMGVAFAS 180 GTY + G FS +GA++ ND HG+HV GT+ A+++G G+ GVA+A+ Sbjct: 101 GTYVD--------------GTPFSVSGAMNGNNDSHGTHVGGTLGASRDGVGMHGVAYAA 146 Query: 181 DYHITNTNGTDSSVYGVNVDYNYFKAAYGNLANAGVRAINSSWGSPDSRDDFSSIGGVAA 240 ++ NTN DS ++G D NYFKAAY LA+AGVRAIN+SWGS + ++ G+ A Sbjct: 147 QVYVANTNQNDSFLFGPTPDPNYFKAAYQALADAGVRAINNSWGSQPKDVSYETLDGLHA 206 Query: 241 AYDRLQGGGKKSWLDAAADVAKESNTLMVWAAGNSAKANINIRSALPYFRPELEQNWIAV 300 AY Q G+ +WLDAAA V+++ + V++AGNS AN ++RSALPYF+P+LE +W+AV Sbjct: 207 AY--AQHYGRSTWLDAAAGVSRQG-VINVFSAGNSGYANASVRSALPYFQPDLEGHWLAV 263 Query: 301 AAINASSVLPSFSNQCGLARYWCVSAPGSAITSLNITSDTDLVNASGTSMAAPHVTGALG 360 + ++ + N+CG+A+YWC++ PG I S N SGTSMAAPH TGAL Sbjct: 264 SGLDQQN--GQRYNRCGIAKYWCITTPGRLINS--TMPGGGYANKSGTSMAAPHATGALA 319 Query: 361 LLMERYPDLDNQAIRTILLTTAKHLGSGPADVPNAMFGWGVPDLNKALNGPGQLLGVFNA 420 L+M+RYP L+N+ +LLTTA L P P GWGVPDL +A++GPGQLLG F A Sbjct: 320 LVMQRYPYLNNEQALQVLLTTATQLDGTPTGAPTDTVGWGVPDLGRAMHGPGQLLGRFEA 379 Query: 421 NIAAGRSDTWSNAISEAALIQRKSDDRAQLAAREAASPD 459 N+ AG D WSN IS++AL+QR+++D A+ AA + D Sbjct: 380 NLPAGLRDEWSNPISDSALLQRQAEDAAEHAAWQRTLKD 418 >NMA0478_1 [O] COG1404 Subtilisin-like serine proteases NmA Neisseria meningitidis Z2491 Length = 604 Score = 117 bits (293), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 123/414 (29%), Positives = 192/414 (46%), Gaps = 58/414 (14%) Query: 78 MNAQYAYAAGFSGLGIKLGAVDSGLL---LSHAEFVTRNVKAVAVTGTYAN-------DG 127 +N + A AG++G G+++G VD+G +S E R K Y N + Sbjct: 117 INLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGR--KEHGYNENYKNYTAYMRKEA 174 Query: 128 SQYQDGSQAWKAGDAFSTTGALSKLND-KHG---------SHVSGTIAAAKNGAGIMGVA 177 + DG + D + +K D +H SH+ G + AG G+A Sbjct: 175 PEDGDGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDVVSHIIGGRSVDGRPAG--GIA 232 Query: 178 FASDYHITNT-NGTDSSVYGVNVDYNYFKAAYGNLANAGVRAINSSWGSPDSRD---DFS 233 + HI NT +GT + + + + A+ L GVR +N+S+G+ SR D Sbjct: 233 PDATLHIMNTHDGTKNEIMSAAI-----RNAWVKLGERGVRIVNNSFGTT-SRAGTADHF 286 Query: 234 SIGGVAAAYDR----LQGGGKKS---WLDAAADVA------KESNTLMVWAAGNSAKANI 280 I Y + GG K L +D + N L +++A N A+A Sbjct: 287 QIANSEEQYRQALLAYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSASNDAQAQP 346 Query: 281 NIRSALPYFRPELEQNWIAVAAINASSVLPSFSNQCGLARYWCVSAPGSAITSLNITSDT 340 N + LP++ + ++ I VA ++ S + SN CG+ WC+SAP A S+ T T Sbjct: 347 NTLTLLPFYEKDAQKGIITVAGVDRSGEKFNGSNHCGITAMWCLSAPYEA--SVRFTR-T 403 Query: 341 DLVNASGTSMAAPHVTGALGLLMERYPDLDNQAIRTILLTTAKHLGSGPADVPNAMFGWG 400 + + +GTS +AP VTG LL+++YP + N +RT LLTTA+ +G+ D + FGWG Sbjct: 404 NPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVGVD---SKFGWG 460 Query: 401 VPDLNKALNGPGQL-LGVFNANIAAGRSD---TWSNAISEAALIQRKSDDRAQL 450 + D KA+NGP G F A+ G SD ++ N IS + +K + QL Sbjct: 461 LLDTGKAMNGPASFPFGDFTAD-TKGTSDIAYSFRNDISGTGGLIKKGGSQLQL 513 >NMB1969_1 [O] COG1404 Subtilisin-like serine proteases Nme Neisseria meningitidis MC58 Length = 618 Score = 111 bits (277), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 100/329 (30%), Positives = 158/329 (48%), Gaps = 52/329 (15%) Query: 158 SHVSGTIAAAKNGAGIMGVAFASDYHITNTNGTDSSVYGVNVDYNYFKAAYGNLANAGVR 217 SH+ G + AG G+A + HI NTN + V + A+ L GVR Sbjct: 215 SHIIGGRSVDGRPAG--GIAPDATLHIMNTNDETKNEMMVAA----IRNAWVKLGERGVR 268 Query: 218 AINSSWGSPDSRDDFSSIGGVAAAYDRLQ------GGGKKSWLDAAADVAKES------- 264 +N+S+G+ SR + + +A + ++ + GG K+ D + ++S Sbjct: 269 IVNNSFGTT-SRAGTADLFQIANSEEQYRQALLDYSGGDKT--DEGIRLMQQSDYGNLSY 325 Query: 265 -----NTLMVWAAGNSAKANINIRSALPYFRPELEQNWIAVAAINASSV----------- 308 N L +++ GN A+A N + LP++ + ++ I VA ++ S Sbjct: 326 HIRNKNMLFIFSTGNDAQAQPNTYALLPFYEKDAQKGIITVAGVDRSGEKFKREMYGEPG 385 Query: 309 ---LPSFSNQCGLARYWCVSAPGSAITSLNITSDTDLVNASGTSMAAPHVTGALGLLMER 365 L SN CG+ WC+SAP A S+ T T+ + +GTS +AP VTG LL+++ Sbjct: 386 TEPLEYGSNHCGITAMWCLSAPYEA--SVRFTR-TNPIQIAGTSFSAPIVTGTAALLLQK 442 Query: 366 YPDLDNQAIRTILLTTAKHLGSGPADVPNAMFGWGVPDLNKALNGPGQL-LGVFNANIAA 424 YP + N +RT LLTTA+ +G+ D + FGWG+ D KA+NGP G F A+ Sbjct: 443 YPWMSNDNLRTTLLTTAQDIGAVGVD---SKFGWGLLDAGKAMNGPASFPFGDFTAD-TK 498 Query: 425 GRSD---TWSNAISEAALIQRKSDDRAQL 450 G SD ++ N IS + +K + QL Sbjct: 499 GTSDIAYSFRNDISGTGGLIKKGGSQLQL 527 >XF0267_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 471 Score = 102 bits (254), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 118/413 (28%), Positives = 177/413 (42%), Gaps = 93/413 (22%) Query: 75 LGAMNAQYAYAAGFSGLGIKLGAVDSGLLLSHAEFVTRNVKAVAVTGTYANDGSQYQDGS 134 L N + A+ GF+G G +G VDSG+ +H VT + K V + N YQD + Sbjct: 16 LDGTNTEPAHTLGFTGKGYMIGVVDSGVNRNH---VTLHDKVV-----HNNVYVDYQDPA 67 Query: 135 QAWKAGDAFSTTGALSKLNDKHGSHVSGTIAAAKNGAGIMGVA------FASDYHITNTN 188 D S HG++V+ IA G+A A + N Sbjct: 68 SP----DDVS----------GHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSSAAEN 113 Query: 189 GTDSSVYGVNVDYNYF-------KAAYGNLANAGVRAINSSWGSPDSRDDFSSIGGVAAA 241 + G N+F K ++ AGVR N+SWG Sbjct: 114 AKQGPIGG-----NFFEGEAAQLKRVNADMIAAGVRIQNNSWG----------------- 151 Query: 242 YDRLQGGGKKSWLDAAA---------DVAKESNTLMVWAAGNSAKANINIRSALPYFRP- 291 Y+ G K+ W+D A D +N L+++A+GN ++ S LP Sbjct: 152 YENQNTGDKQVWIDPAVTDAFVNVYRDFVLNNNGLVIFASGNYSQQQPGRLSRLPSLPTV 211 Query: 292 -------ELEQNWIAVAAINASSV---LPSFSNQCGLARYWCVSAPGSAI------TSLN 335 +LE+ W+ VAA+++ L S+SN CG+A ++C++APG I T+ Sbjct: 212 EGGASPADLERGWLVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDLIEIDPNVTTSP 271 Query: 336 ITSDTDLVNA----SGTSMAAPHVTGALGLLMERYPDLDNQAIRTILLTTAKHLGSGPAD 391 + D +N +GTS AAP V+GA L+ E +P N +R LL TA LG+ D Sbjct: 272 VDGDKGYLNGYLIQNGTSFAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGAPGVD 331 Query: 392 VPNAMFGWGVPDLNKALNGPGQL-LGVFNANIAAGRSDTWSNAIS-EAALIQR 442 +FG+G ++ KA+ GP + G + RS TW N I+ LI+R Sbjct: 332 ---EVFGYGALNVGKAVLGPAKFDWGDVQVSFDDRRS-TWGNDITGSGGLIKR 380 >XF1026_1 [O] COG1404 Subtilisin-like serine proteases Xfa Xylella fastidiosa 9a5c Length = 466 Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 114/408 (27%), Positives = 175/408 (42%), Gaps = 88/408 (21%) Query: 75 LGAMNAQYAYAAGFSGLGIKLGAVDSGLLLSHAEFVTRNVKAVAVTGTYANDGSQYQDGS 134 L N + A GF+G G +G VDSG+ +H VT + + + + N YQD + Sbjct: 16 LDGTNTEPARTLGFTGKGYMIGVVDSGVNRNH---VTLHNQVI-----HNNVYVDYQDPA 67 Query: 135 QAWKAGDAFSTTGALSKLNDKHGSHVSGTIAAAKNGAGIMGVA------FASDYHITNTN 188 + D S HG++V+ IA G+A A + + Sbjct: 68 SS----DDVS----------GHGTNVAQLIAGQPVEYWPGGIAPGATIFSARVFSSAAES 113 Query: 189 GTDSSVYGVNVDYNYF-------KAAYGNLANAGVRAINSSWGSPDSRDDFSSIGGVAAA 241 + S+ G N+F K ++ AGVR N+SWG Sbjct: 114 AKEGSISG-----NFFERETAQLKRVNADMIAAGVRIQNNSWG----------------- 151 Query: 242 YDRLQGGGKKSW---------LDAAADVAKESNTLMVWAAGNSAKANINIRSALPYFRP- 291 Y+ GG+ W ++A D +N L+V+A+GN A+ + LP Sbjct: 152 YESEDTGGEPVWRSPITTGLFVNAYRDFVLNNNGLVVFASGNEAQPQPGQLARLPSLPTV 211 Query: 292 -------ELEQNWIAVAAINASSV---LPSFSNQCGLARYWCVSAPGSAITSLNITS--- 338 +LE+ W+ VAA+++ L S+SN CG+A ++C++APG + N + Sbjct: 212 EGGASPADLERGWLVVAALDSFDHPDQLTSYSNHCGIAMHYCLAAPGDVVVIHNSVTNSS 271 Query: 339 --DTDLVNASGTSMAAPHVTGALGLLMERYPDLDNQAIRTILLTTAKHLGSGPADVPNAM 396 D + GTS AAP V+GA L+ E +P N +R LL TA LG D + Sbjct: 272 SVDDEYYELQGTSFAAPLVSGAAALVWEAFPYFSNDLVRQTLLGTATDLGVPGVD---EV 328 Query: 397 FGWGVPDLNKALNGPGQL-LGVFNANIAAGRSDTWSNAIS-EAALIQR 442 FG+G ++ KA+ GP + G + RS TW N I+ LI+R Sbjct: 329 FGYGALNVGKAVLGPAKFDWGDVQVSFDDRRS-TWGNDITGSGGLIKR 375