BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0489.p (298 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2109 [GER] COG0697 Permeases of the drug/metabolite transport... 408 e-113 yddG [GER] COG0697 Permeases of the drug/metabolite transporter ... 346 4e-95 ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter... 346 4e-95 ECs2077 [GER] COG0697 Permeases of the drug/metabolite transport... 346 4e-95 STM1571 [GER] COG0697 Permeases of the drug/metabolite transport... 292 6e-79 >RSc2109 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 408 bits (1048), Expect = e-113, Method: Compositional matrix adjust. Identities = 205/296 (69%), Positives = 245/296 (82%), Gaps = 1/296 (0%) Query: 1 MNSKKATLIGLSAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASLILMVSVGFPRLSSF 60 + +KATLIGL AVVLWS+IVGL+RGVS LGA GGAA +YTV S+ L+ SVGF ++++F Sbjct: 2 QSKRKATLIGLIAVVLWSSIVGLLRGVSASLGAVGGAAMMYTVVSIFLLFSVGFIKVNAF 61 Query: 61 PRRYLVWGSVLFVAYELCLSLSIGYAHTGRQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 PRRYLVWGS+LFV+YELCLSLSIGYA++ RQAIEVGMVNYLWPTFT++ AI F Q + L Sbjct: 62 PRRYLVWGSILFVSYELCLSLSIGYANSDRQAIEVGMVNYLWPTFTMLFAIAFNRQPSNL 121 Query: 121 LVVPGFILSMLGICWVLGGNQGLDLPVMLANIQDNPLSYGLAFIGALIWAAYCTVTTRIA 180 L++PG ++++LGIC VLGG+QGLD M ANIQDNPLSYGLA GALIWAAYC VT+R+A Sbjct: 122 LIIPGVLVAILGICQVLGGDQGLDFAGMAANIQDNPLSYGLALSGALIWAAYCAVTSRMA 181 Query: 181 EGRNGVTPFFMLVALALWVKVLLGGHAAELSFSVPALVYLLLAAAAMGLGYAAWNVGILH 240 EG+NG+T FFML ALALW+K L G A + FS A++YL++AA AMG GYAAWNVGILH Sbjct: 182 EGKNGITLFFMLTALALWIKYLATGGGA-MHFSYQAILYLVMAACAMGFGYAAWNVGILH 240 Query: 241 GNVTVLAGASYFIPVLSSALSAALLRAPLPPSFWVGAALVCAGSILCWRATAAGRK 296 GNVTVLAGASYFIPV S+AL+A LLR PL +FW GA++VCAGSILCW AT R Sbjct: 241 GNVTVLAGASYFIPVFSAALAATLLRTPLSSAFWKGASMVCAGSILCWLATRGQRS 296 >yddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 293 Score = 346 bits (887), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 176/294 (59%), Positives = 221/294 (75%), Gaps = 1/294 (0%) Query: 1 MNSKKATLIGLSAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASLILMVSVGFPRLSSF 60 M +KATLIGL A+VLWS +VGLIRGVSE LG GGAAAIY+++ L+L+ +VGFPR+ Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLVWGSVLFVAYELCLSLSIGYAHTGRQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YL+ GS+LFV+YE+CL+LS+GYA T QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFILSMLGICWVLGGNQGLDLPVMLANIQDNPLSYGLAFIGALIWAAYCTVTTRIA 180 L+VPG +L+++G+CWVLGG+ GL ++ NI +PLSY LAFIGA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 EGRNGVTPFFMLVALALWVKVLLGGHAAELSFSVPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F +L +LWV L E+ FS P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMIFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVLSSALSAALLRAPLPPSFWVGAALVCAGSILCWRATAAG 294 GNVT++A SYF PVLSSAL+A LL APL SFW GA +VC GS+LCW AT G Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG 293 >ZyddG [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 346 bits (887), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 176/294 (59%), Positives = 221/294 (75%), Gaps = 1/294 (0%) Query: 1 MNSKKATLIGLSAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASLILMVSVGFPRLSSF 60 M +KATLIGL A+VLWS +VGLIRGVSE LG GGAAAIY+++ L+L+ +VGFPR+ Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLVWGSVLFVAYELCLSLSIGYAHTGRQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YL+ GS+LFV+YE+CL+LS+GYA T QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFILSMLGICWVLGGNQGLDLPVMLANIQDNPLSYGLAFIGALIWAAYCTVTTRIA 180 L+VPG +L+++G+CWVLGG+ GL ++ NI +PLSY LAFIGA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 EGRNGVTPFFMLVALALWVKVLLGGHAAELSFSVPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F +L +LWV L E+ FS P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVLSSALSAALLRAPLPPSFWVGAALVCAGSILCWRATAAG 294 GNVT++A SYF PVLSSAL+A LL APL SFW GA +VC GS+LCW AT G Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG 293 >ECs2077 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 293 Score = 346 bits (887), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 176/294 (59%), Positives = 221/294 (75%), Gaps = 1/294 (0%) Query: 1 MNSKKATLIGLSAVVLWSAIVGLIRGVSEHLGATGGAAAIYTVASLILMVSVGFPRLSSF 60 M +KATLIGL A+VLWS +VGLIRGVSE LG GGAAAIY+++ L+L+ +VGFPR+ Sbjct: 1 MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQI 60 Query: 61 PRRYLVWGSVLFVAYELCLSLSIGYAHTGRQAIEVGMVNYLWPTFTLVAAILFGGQRATL 120 P+ YL+ GS+LFV+YE+CL+LS+GYA T QAIEVGMVNYLWP+ T++ AILF GQ+ Sbjct: 61 PKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNW 120 Query: 121 LVVPGFILSMLGICWVLGGNQGLDLPVMLANIQDNPLSYGLAFIGALIWAAYCTVTTRIA 180 L+VPG +L+++G+CWVLGG+ GL ++ NI +PLSY LAFIGA IWAAYCTVT + A Sbjct: 121 LIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYA 180 Query: 181 EGRNGVTPFFMLVALALWVKVLLGGHAAELSFSVPALVYLLLAAAAMGLGYAAWNVGILH 240 G NG+T F +L +LWV L E+ FS P ++ L+ AA +G YAAWNVGILH Sbjct: 181 RGFNGITVFVLLTGASLWVYYFLTPQ-PEMVFSTPVMIKLISAAFTLGFAYAAWNVGILH 239 Query: 241 GNVTVLAGASYFIPVLSSALSAALLRAPLPPSFWVGAALVCAGSILCWRATAAG 294 GNVT++A SYF PVLSSAL+A LL APL SFW GA +VC GS+LCW AT G Sbjct: 240 GNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG 293 >STM1571 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 274 Score = 292 bits (748), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 157/272 (57%), Positives = 203/272 (74%), Gaps = 1/272 (0%) Query: 20 IVGLIRGVSEHLGATGGAAAIYTVASLILMVSVGFPRLSSFPRRYLVWGSVLFVAYELCL 79 +VGLIRGVSE LG GGAA IY+++ L+L+ +VG P + FP RYL+ GSVLFV+YE+CL Sbjct: 1 MVGLIRGVSEGLGPVGGAAMIYSLSGLLLIFTVGLPDIRRFPGRYLIAGSVLFVSYEICL 60 Query: 80 SLSIGYAHTGRQAIEVGMVNYLWPTFTLVAAILFGGQRATLLVVPGFILSMLGICWVLGG 139 +LS+GYA T QAIEVGMVNYLWP+ T++ AILF GQ+ L+VPG ++++ G+CWVLGG Sbjct: 61 ALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLIALTGVCWVLGG 120 Query: 140 NQGLDLPVMLANIQDNPLSYGLAFIGALIWAAYCTVTTRIAEGRNGVTPFFMLVALALWV 199 GL+ +++N+ +PLSY LAF+GA IWA YCTVT + A G NG+T F +L A+ALW+ Sbjct: 121 ENGLNPGEIISNVATSPLSYLLAFLGAFIWATYCTVTNKYARGFNGITVFVLLTAVALWL 180 Query: 200 KVLLGGHAAELSFSVPALVYLLLAAAAMGLGYAAWNVGILHGNVTVLAGASYFIPVLSSA 259 L A + FS+P + L AA +G YAAWNVGILHGNVT++A SYF PV+SSA Sbjct: 181 HYFLTPQPAMI-FSLPVIAKLFTAALTLGFAYAAWNVGILHGNVTIMAVGSYFTPVMSSA 239 Query: 260 LSAALLRAPLPPSFWVGAALVCAGSILCWRAT 291 L+A LL +PL SFW GA +VC GS+LCW AT Sbjct: 240 LAALLLSSPLSFSFWQGAVMVCVGSLLCWLAT 271