BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0389.p (317 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2507 [GER] COG0697 Permeases of the drug/metabolite transport... 175 1e-43 VCA0090 [GER] COG0697 Permeases of the drug/metabolite transport... 166 7e-41 AGc3767 [GER] COG0697 Permeases of the drug/metabolite transport... 124 3e-28 BH0396 [GER] COG0697 Permeases of the drug/metabolite transporte... 119 6e-27 SMc01844 [GER] COG0697 Permeases of the drug/metabolite transpor... 93 8e-19 >RSc2507 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 310 Score = 175 bits (443), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 125/282 (44%), Positives = 176/282 (62%), Gaps = 4/282 (1%) Query: 1 MSSSNIAKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLSLLAFARMRGVPLQW 60 M S+ +LL+LAA+WG SF+ MR+AAP FGP+ R ++A+ LL MRG Sbjct: 1 MRRSDAIELLILAALWGGSFLFMRVAAPPFGPVALIALRVAIASAFLLPVLAMRGGLGAL 60 Query: 61 RRNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLAPIFTAMFGFLLLGERLSLV 120 R +W L +G+ N+A+PF L A++ L + + + + +N+ AP+F A+ F LGER+S Sbjct: 61 RPHWPHLLAVGVLNSAVPFCLLAYAELTLTAGFTSVLNAAAPLFAAIVAFAWLGERMSAW 120 Query: 121 RTGAFVLGLVGVAVLVGIGPAPVDA-LVIAGVLAAMGAAVSYGFAATFTRMRAGGIPPIA 179 R +G VGV VLVG G + +DA V AA+GA V YG A ++ + G+PP+A Sbjct: 121 RVLGLAIGFVGVIVLVG-GSSALDARQGGLAVAAALGATVLYGLAGSYAKRYLTGVPPLA 179 Query: 180 MATGSQFAAALCLLPLAAPSMPHALQAGTLPALLSVLVLGVVCTGIAYALFFQLIAAEGA 239 +ATGSQ AAA+ L PLA P G++ L V+ LG+ CTGIAY LFF+LIA G Sbjct: 180 VATGSQIAAAVVLAPLAVWLWPAHTPTGSV--WLHVIGLGIACTGIAYILFFRLIAHVGP 237 Query: 240 TKAITVTFLVPMTASLWGWLLLDEPVTVGTVTGIAVVLIATA 281 T+A++VTFLVP+ LWG L L E +T+ V G AV+L+ T+ Sbjct: 238 TRAVSVTFLVPVFGVLWGILFLGEQLTLNMVAGCAVILLGTS 279 >VCA0090 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Vch Vibrio cholerae Length = 297 Score = 166 bits (420), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 117/303 (38%), Positives = 175/303 (57%), Gaps = 15/303 (4%) Query: 1 MSSSNIAKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLSLLAFARM--RGVPL 58 MS N+ +LL LAAIWG SF+ MRIAA FGP R A LSL A++ R +P+ Sbjct: 1 MSLVNLLQLLCLAAIWGGSFLFMRIAAHSFGPAYLIEARVGFAALSLFLVAQLLRRSLPI 60 Query: 59 QWRRNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLAPIFTAMFGFLLLGERLS 118 R++W +L++G+ NTA+PF LFA++AL + + ++ +NS API+ A+ GFL G LS Sbjct: 61 --RQHWPHFLILGLINTAVPFLLFAYAALTLNVSTLSILNSTAPIWGAVIGFLWHGTPLS 118 Query: 119 LVRTGAFVLGLVGVAVLVGIGPAPVDALVIAGVLAAMGAAVSYGFAATFTRMRAGGIPPI 178 +LG+ GVAV+VG + ++ A AA SYG A +T+ +A + Sbjct: 119 RKAVAGLLLGVSGVAVIVGWDMVAIGHHAALPMVCAALAAASYGLATNYTK-QAPQLSAF 177 Query: 179 AMATGSQFAAALCLLPLA----APSMPHALQAGTLPALLSVLVLGVVCTGIAYALFFQLI 234 A GS +AA L + PL P +L+ G +V++LGV+CTG+AY ++F+L+ Sbjct: 178 ENAHGSMWAACLWVAPLMWFVPLRETPSSLEWG------AVILLGVICTGLAYLIYFRLV 231 Query: 235 AAEGATKAITVTFLVPMTASLWGWLLLDEPVTVGTVTGIAVVLIATATALRAKPXTSRTA 294 A GA ++VTFL+P+ LWG+ +LDEP+ + T+ G +VL T +R + Sbjct: 232 KAIGAASTLSVTFLIPVFGILWGYWILDEPIGLNTLFGTLLVLAGTMLVTGFSLRNARLS 291 Query: 295 RTP 297 R P Sbjct: 292 RQP 294 >AGc3767 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 329 Score = 124 bits (311), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 96/291 (32%), Positives = 153/291 (52%), Gaps = 27/291 (9%) Query: 1 MSSSNIAKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLSLLAFARMRGV--PL 58 M + A L+ L+ +WG SF + +A P+ R SLA ++LL R+ G+ P Sbjct: 27 MDAREWAMLIALSLLWGGSFFFIGVAVKELPPVTIVTLRVSLAAVALLVVCRIMGLRLPR 86 Query: 59 QWRRNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLAPIFTAMFG-FLLLGERL 117 +W W + +G+ N +PF L W I S + +N+ P+FT + FL E++ Sbjct: 87 EWAV-WRAFFGMGLLNNIIPFCLIVWGQTQIASGLASILNATTPLFTVIVAHFLTADEKM 145 Query: 118 SLVRTGAFVLGLVGVAVLVGIGPAPVDALV-IAGVLAAMGAAVSYGFAATF-TRMRAGGI 175 + + ++G VGVA + IGPA + G +A +GAA+SY FA F R +A G+ Sbjct: 146 TGNKLAGVLIGFVGVATM--IGPAAFGGSSGLWGQIAILGAAISYSFAGIFGRRFKAMGV 203 Query: 176 PPIAMATGSQFAAALCLLP----------LAAPSMPHALQAGTLPALLSVLVLGVVCTGI 225 PP+ ATG ++ L L+P LA P + GT AL+ + +L T + Sbjct: 204 PPLMTATGQISSSTLMLIPAALLIDKPWTLAMPGL------GTWGALIGIALL---STAL 254 Query: 226 AYALFFQLIAAEGATKAITVTFLVPMTASLWGWLLLDEPVTVGTVTGIAVV 276 AY +FF+++A+ GAT VTFL+P++A L G L+L E + + G+A++ Sbjct: 255 AYLIFFRILASAGATNLALVTFLIPVSAILLGSLILGEQLEIKHFAGMAMI 305 >BH0396 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bha Bacillus halodurans Length = 305 Score = 119 bits (299), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 91/295 (30%), Positives = 139/295 (47%), Gaps = 8/295 (2%) Query: 9 LLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLSLLAFARMRGVPLQWRRNWLPYL 68 LL L+ IWG SF+ + + G T R + LL MR W + Sbjct: 7 LLSLSLIWGFSFVFIEHLLGIVGVWGTVVVRCFAGAIILLPILLMRRKLFYRPAPWKALM 66 Query: 69 VIGIFNTALPFALFAWSALHIPSAYMATMNSLAPIFTAMFGFLLLGERLSLVRTGAFVLG 128 ++GIFN LP+ L A S I S+ A +N+L P+FT + GFLL LS + G VLG Sbjct: 67 IVGIFNAGLPWGLIALSQTEIYSSTAAVLNALTPLFTGLIGFLLYSNALSRQQWGGIVLG 126 Query: 129 LVGVAVLVGIGPAPVDALVIAGVLAAMGAAVSYGFAATFTRMRAGGIPPIAMATGSQFAA 188 GV VL G + GV + A + YGFA+ + + + + T S Sbjct: 127 FSGVVVLTGFQLQLLAPEHFVGVGTMILATICYGFASQYVKRHLHDTDVVLITTFSLLFG 186 Query: 189 ALCLLPLAAPSMPHALQAGTLP------ALLSVLVLGVVCTGIAYALFFQLIAAEGATKA 242 L+ L + +L +P +L+S++ LG + +G+A+ L++ L+ G A Sbjct: 187 G--LVGLIGMWITDSLHVVRVPLTIDWLSLISIIGLGCLGSGMAHLLYYDLMKKGGPEFA 244 Query: 243 ITVTFLVPMTASLWGWLLLDEPVTVGTVTGIAVVLIATATALRAKPXTSRTARTP 297 TVT+L+PMTA +WG L LDE +T V G+ ++L+ R + S+ Sbjct: 245 TTVTYLIPMTAIIWGKLFLDELITKNIVIGMLMILMGVYFTSRKRNVCSKANEDS 299 >SMc01844 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 314 Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 76/226 (33%), Positives = 116/226 (51%), Gaps = 18/226 (7%) Query: 63 NWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLAPIFTAMFGFL-LLGERLSLVR 121 W +L++G+ N A+P A HI + A +N+ P++T + + E+LS + Sbjct: 75 RWREFLLMGLINNAIPHAFIFLGQTHIGAGLAAILNATTPVWTVLIANVATEDEKLSTAK 134 Query: 122 TGAFVLGLVGVAVLVG----------IGPAPVDALVIAGVLAAMGAAVSYGFAATFTRMR 171 +LGL G VL+G G P+ ALV+ + AAVSYGF+AT+ + Sbjct: 135 FSGCLLGLAGTVVLIGPSALAGLFGTAGDVPLWALVLPVL-----AAVSYGFSATYGKRF 189 Query: 172 AGGIPPIAMATGSQFAAALCLLPLAA-PSMPHALQAGTLPALLSVLVLGVVCTGIAYALF 230 PP+ A G A+ L +LP+A MP + L +L++L L +V T AY LF Sbjct: 190 RDLAPPVT-AAGQLTASTLIMLPVAVLVDMPWTMPMPPLTTVLAILGLALVSTAYAYILF 248 Query: 231 FQLIAAEGATKAITVTFLVPMTASLWGWLLLDEPVTVGTVTGIAVV 276 F+++A GAT VT LVP +A L G+L L E + V G+ ++ Sbjct: 249 FRIMAEAGATNTSLVTLLVPPSAILLGYLFLGEMLQATDVGGMLLI 294