BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0371.p (474 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA571 [GEPR] COG0477 Permeases of the major facilitator superf... 169 2e-41 PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 136 1e-31 ydjK [GEPR] COG0477 Permeases of the major facilitator superfami... 129 2e-29 Z2813 [GEPR] COG0477 Permeases of the major facilitator superfam... 127 5e-29 ECs2484 [GEPR] COG0477 Permeases of the major facilitator superf... 127 5e-29 >AGpA571 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 461 Score = 169 bits (427), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 139/482 (28%), Positives = 230/482 (47%), Gaps = 45/482 (9%) Query: 2 IATPSATIPARLDRLPWSR---WHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLAL 58 +A P A I ARL+RLP +R W +V G A DG V + VL R L Sbjct: 14 VADPQADISARLERLPITREVFWARNIV---GAATFFDGYTVIAIAYAMPVLVRE--WGL 68 Query: 59 DAAQVGWTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLA 118 +Q G S+ G ++GA++FG L +R+GR ++ + T++L+++ +A FA + Sbjct: 69 TPSQTGMILSMGYLGQLIGAILFGWLAERIGRLKVLLFTILLFVSMDVACLFAAGAGMMM 128 Query: 119 LCRFVTGLGIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQV 178 RFV G+G GGE ++ I+EL+ ++ RGR L+ F +G +GAGL + P Sbjct: 129 AFRFVQGIGTGGEVPVASAYINELIGSKGRGRFFLLYEVMFLLG-LVGAGLIGYFMVP-- 185 Query: 179 MGAALGWRACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHG 238 GW+A F++G V A+ ++ +R + ESPRWL GR+ EA +V+R+E Sbjct: 186 ---LYGWKAMFIVGLVPAMLMIPLRWFLKESPRWLAATGRYDEANVIVKRMEESARAAGK 242 Query: 239 PLPAVELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFT 298 LP + + + + WRE+ + Y +R++ + M V N Sbjct: 243 ALPEPRIIATPAKRVSD-------WRELFQGI---YLKRTLSIWAMWFCAYMVANGTITW 292 Query: 299 YSLVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAA 358 + + F +P LY F + V+ ++ L D +GR+R A LL+ LA Sbjct: 293 LPTLYRQTFNLPLETSILYGFMTSAAGVVAAVICALLIDKVGRKRWYAGALLLAPVPLAI 352 Query: 359 TAWAFNAGMLDARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTG- 417 AW G + + + + S YL ++E++P RMR AIGTG Sbjct: 353 LAW---LGATSPMQVLIFAGLAYAIVQTVTFSLYLYSAEIYPTRMR--------AIGTGA 401 Query: 418 ------VGGFVAPVLLGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEE 471 +G P+L+G++++S V A +A + ++ V + FAV+ + + LEE Sbjct: 402 GSAWLRLGSSAGPMLVGFVMSSMGIQYVFATFAF---ILIIGAVVTMLFAVETKGKVLEE 458 Query: 472 VA 473 ++ Sbjct: 459 LS 460 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 136 bits (342), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 140/473 (29%), Positives = 221/473 (46%), Gaps = 30/473 (6%) Query: 7 ATIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSL-GSVLERSDTLALDAAQVGW 65 A+ RL+RLP S +H V + + +A+ D +++ ++ L GS+ LD+AQ G Sbjct: 6 ASAAERLERLPLSPYHRLVFVIIALAFFFDSMDLAMMTFLLGSI---KAEFGLDSAQAGL 62 Query: 66 TGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVTG 125 S G V+GA + G L DR GRK +F +++L+ A+ + A D L R + G Sbjct: 63 LASSSFFGMVIGAALSGMLADRFGRKPVFQASIVLWGLASYLCSTAGDLDSLTFYRVLLG 122 Query: 126 LGIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMGAALGW 185 +G+G E+ S + E++PA RG+ +++ FW + AG L P GW Sbjct: 123 IGMGMEFPIAQSLLSEMIPASRRGKYIALMDG-FWPLGFVAAGCLSYFLLPLT-----GW 176 Query: 186 RACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPLPAVEL 245 R+ FL+ A+ AV VL +R +PESPRWL GR +A+ V+R IEA V + G EL Sbjct: 177 RSIFLVLALPAVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVMRSLG---LTEL 233 Query: 246 APS-ASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMV-ALMMVAQAFVYNAIFFTYSLVL 303 P Q + G + A + YR+R++ V L A Y + +L+ Sbjct: 234 PPPLRQPQRERSRPGF--FSAFAELWSPAYRRRTLTVWGLWFFALLGFYGLTSWLSALLQ 291 Query: 304 TRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAATAWAF 363 F V + Y +L + G L L +S GR+ + +L G G A A+A+ Sbjct: 292 QSGFAV--TQSVYYTVLISLAGIPGFLCAAWLVESWGRKP--SCVLMLLGGG--AMAYAY 345 Query: 364 NAGMLDARSLALCWS---AVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVGG 420 + SLAL A+ F + Y E++P RA A+G +G Sbjct: 346 GQTAVFGGSLALLIGFGLAMQFFLFGMWAVLYTYTPELYPTSARATGSGFASAVGR-IGS 404 Query: 421 FVAPVLLGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVA 473 + P++ G ++ + V + LGA +A + F ++ RTLEE+A Sbjct: 405 LLGPLVTGLVLPLTGQGGV---FTLGALCFGVAALVVWAFGIETRGRTLEELA 454 >ydjK [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 459 Score = 129 bits (323), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 114/346 (32%), Positives = 168/346 (48%), Gaps = 37/346 (10%) Query: 11 ARLDRLPWSRWHWRV--VIALG--VAW--VLDGLEVTLVGSLGSVLERSDTLALDAAQVG 64 ARLDRLP RWH + ++A G V W + GL + + +LG + S T A Sbjct: 11 ARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGLILAQLKALGWT-DNSTTATFSA---- 65 Query: 65 WTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVT 124 + AG LGALV G + D+ GR+ F+L +++A+ + AF+ + FL CRFV Sbjct: 66 ----ITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVM 121 Query: 125 GLGIGGEYAAINSAIDELVPARVRG----RVNLIINASFWIGAALGAGLSLVILDPQVMG 180 G+G+G + + E +P R RG RV+ I N S+ + + + GL+ +I Sbjct: 122 GVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLI------S 175 Query: 181 AALGWRACFLLGAVLA-VAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHG- 238 A WR L+ A+L+ +A L R+ PESPRWL GR+ EAE V+R IE V +Q G Sbjct: 176 AEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRQTGK 235 Query: 239 PLPAVELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFT 298 PLP V +A S +L VLL R S ++ M V Q Y I + Sbjct: 236 PLPPVVIADDGKAPQAVPYSALL-----TGVLLKRVILGSCVLIAMNVVQ---YTLINWL 287 Query: 299 YSLVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRM 344 ++ +T+ + D V + F G G + + D I R+ M Sbjct: 288 PTIFMTQGINLKDSIVLNTMSMF--GAPFGIFIAMLVMDKIPRKTM 331 >Z2813 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 459 Score = 127 bits (320), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 113/346 (32%), Positives = 167/346 (48%), Gaps = 37/346 (10%) Query: 11 ARLDRLPWSRWHWRV--VIALG--VAW--VLDGLEVTLVGSLGSVLERSDTLALDAAQVG 64 ARLDRLP RWH + ++A G V W + GL + + +LG + S T A Sbjct: 11 ARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGLILAQLKALGWT-DNSTTATFSA---- 65 Query: 65 WTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVT 124 + AG LGALV G + D+ GR+ F+L +++A+ + AF+ + FL CRFV Sbjct: 66 ----ITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVM 121 Query: 125 GLGIGGEYAAINSAIDELVPARVRG----RVNLIINASFWIGAALGAGLSLVILDPQVMG 180 G+G+G + + E +P R RG RV+ I N S+ + + + GL+ +I Sbjct: 122 GVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLI------S 175 Query: 181 AALGWRACFLLGAVLA-VAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHG- 238 A WR L+ A+L+ +A L R+ PESPRWL GR+ EAE V+R IE V + G Sbjct: 176 AEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRHTGK 235 Query: 239 PLPAVELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFT 298 PLP V +A S +L VLL R S ++ M V Q Y I + Sbjct: 236 PLPPVVIADDGKAPQAVPYSALL-----TGVLLKRVILGSCVLIAMNVVQ---YTLINWL 287 Query: 299 YSLVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRM 344 ++ +T+ + D V + F G G + + D I R+ M Sbjct: 288 PTIFMTQGINLKDSIVLNTMSMF--GTPFGIFIAMLVMDKIPRKTM 331 >ECs2484 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 459 Score = 127 bits (320), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 113/346 (32%), Positives = 167/346 (48%), Gaps = 37/346 (10%) Query: 11 ARLDRLPWSRWHWRV--VIALG--VAW--VLDGLEVTLVGSLGSVLERSDTLALDAAQVG 64 ARLDRLP RWH + ++A G V W + GL + + +LG + S T A Sbjct: 11 ARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGLILAQLKALGWT-DNSTTATFSA---- 65 Query: 65 WTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVT 124 + AG LGALV G + D+ GR+ F+L +++A+ + AF+ + FL CRFV Sbjct: 66 ----ITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVM 121 Query: 125 GLGIGGEYAAINSAIDELVPARVRG----RVNLIINASFWIGAALGAGLSLVILDPQVMG 180 G+G+G + + E +P R RG RV+ I N S+ + + + GL+ +I Sbjct: 122 GVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSYPLCSLIAMGLTPLI------S 175 Query: 181 AALGWRACFLLGAVLA-VAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHG- 238 A WR L+ A+L+ +A L R+ PESPRWL GR+ EAE V+R IE V + G Sbjct: 176 AEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRHTGK 235 Query: 239 PLPAVELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFT 298 PLP V +A S +L VLL R S ++ M V Q Y I + Sbjct: 236 PLPPVVIADDGKAPQAVPYSALL-----TGVLLKRVILGSCVLIAMNVVQ---YTLINWL 287 Query: 299 YSLVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRM 344 ++ +T+ + D V + F G G + + D I R+ M Sbjct: 288 PTIFMTQGINLKDSIVLNTMSMF--GTPFGIFIAMLVMDKIPRKTM 331