BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0360.p (591 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1502 [R] COG3960 Glyoxylate carboligase Pae Pseudomonas aerugi... 985 0.0 STM0517 [R] COG3960 Glyoxylate carboligase Sty Salmonella typhim... 967 0.0 gcl [R] COG3960 Glyoxylate carboligase Eco Escherichia coli K12 967 0.0 Zgcl [R] COG3960 Glyoxylate carboligase EcZ Escherichia coli O15... 967 0.0 ECs0568 [R] COG3960 Glyoxylate carboligase Ecs Escherichia coli ... 967 0.0 >PA1502 [R] COG3960 Glyoxylate carboligase Pae Pseudomonas aeruginosa Length = 591 Score = 985 bits (2546), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/591 (79%), Positives = 519/591 (87%) Query: 1 MAKMRAVDAAVHVLVKEGCLQAFGVPGAAINPFYSALKKHGGISHILARHVEGASHMAEG 60 MA+MRA++AAV V+ +EG AFGVPGAAINP Y+ALKK GGI H+LARHVEGASHMAEG Sbjct: 1 MARMRAIEAAVLVMRREGVDTAFGVPGAAINPMYAALKKIGGIDHVLARHVEGASHMAEG 60 Query: 61 YTRAKAGNIGLCIGTSGPAGTDMITGLYSAQADSIPILCVTGQAPRARLYKEDFQAVDIE 120 YTR KAGNIG+CIGTSGPAGTDMITGLYSA ADSIPILC+TGQAPRARL+KEDFQAVDI Sbjct: 61 YTRTKAGNIGVCIGTSGPAGTDMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIS 120 Query: 121 SIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFDVQMAEIDFDPDTYTP 180 SIA PV KWA TV EPA VP VFQ+AF LMRS RPGPVLIDLPFDVQMAEI+FD D Y P Sbjct: 121 SIAAPVAKWATTVLEPAQVPYVFQKAFQLMRSDRPGPVLIDLPFDVQMAEIEFDIDAYEP 180 Query: 181 LPVYRPAATRAQIEKAFDMLNAAQRPLLTIGGGVVNADAAALAVEFAELTGVPVIPTLMA 240 LPV +P ATR Q EK ML+ A+RPLL GGG+ NADAA EFAELTG+PVIPTLM Sbjct: 181 LPVSKPKATRVQAEKVLAMLDEAERPLLVAGGGIFNADAAERFREFAELTGIPVIPTLMG 240 Query: 241 WGAIADDHPQMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSIDVFTKGRTFVH 300 WG I DDHPQMAGMVGLQTSHRYGNATLL SD VLGIGNRWANRHTGS++V+T+GR F+H Sbjct: 241 WGVIPDDHPQMAGMVGLQTSHRYGNATLLESDLVLGIGNRWANRHTGSVEVYTEGRRFIH 300 Query: 301 VDIEPTQIGRVFGPDYGIVSDAGAALKLFVEVAKEWKTAGRLPDRSAWLAECQQRKKSLQ 360 VDIEPTQIGRVF PD GIVSDAGAAL F+EVA+EWK AG+L R+AWL CQQRK++LQ Sbjct: 301 VDIEPTQIGRVFMPDLGIVSDAGAALDAFLEVAREWKAAGKLKSRAAWLESCQQRKRTLQ 360 Query: 361 RRTHFNDTPVKPQRVYEEMNRAFGRETCYVATIGLSQIAAAQFLHVYRDRHWINCGQAGP 420 R+THF++ PVKPQRVYEEMN FG++ CYV+TIGLSQIA AQFLHVY+ RHWINCGQAGP Sbjct: 361 RKTHFDNVPVKPQRVYEEMNEFFGKDACYVSTIGLSQIAGAQFLHVYQPRHWINCGQAGP 420 Query: 421 LGWTIPAALGVVAADPQKKVVAISGDYDFQFMIEELAVGAQFKLPYLHVLVNNSYLGLIR 480 LGWTIPAALGVV ADP ++VVA+SGDYDFQFMIEELAVGAQFKLPY+HVLVNNSYLGLIR Sbjct: 421 LGWTIPAALGVVKADPSRQVVALSGDYDFQFMIEELAVGAQFKLPYIHVLVNNSYLGLIR 480 Query: 481 QAQRGFEMDYCVQLAFENINAPELNGYGVDHVAVVEGLGCKAIRVTDPNAIQDAFAQAQR 540 QAQRGF+MDYCVQLAF+NINAPEL GYGVDHVAVVEGLGCKAIRV DPN I A A+A+ Sbjct: 481 QAQRGFDMDYCVQLAFDNINAPELEGYGVDHVAVVEGLGCKAIRVFDPNEIGAALAKARE 540 Query: 541 WMAEYRVPVVVEIILERVTNIAMGTEIDAINEFEPLAERADDAPTAISLLD 591 M +++VPVVVE+ILER+TNI+MGTEI+AINEFE LAE+ DAPTAISLLD Sbjct: 541 LMQQHQVPVVVEVILERITNISMGTEINAINEFEELAEKGADAPTAISLLD 591 >STM0517 [R] COG3960 Glyoxylate carboligase Sty Salmonella typhimurium LT2 Length = 593 Score = 967 bits (2501), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/590 (76%), Positives = 516/590 (87%) Query: 1 MAKMRAVDAAVHVLVKEGCLQAFGVPGAAINPFYSALKKHGGISHILARHVEGASHMAEG 60 MAKMRAVDAA++VL KEG AFGVPGAAINPFYSA++KHGGI HILARHVEGASHMAEG Sbjct: 1 MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEG 60 Query: 61 YTRAKAGNIGLCIGTSGPAGTDMITGLYSAQADSIPILCVTGQAPRARLYKEDFQAVDIE 120 YTRA AGNIG+C+GTSGPAGTDMIT LYSA ADSIPILC+TGQAPRARL+KEDFQAVDIE Sbjct: 61 YTRAAAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIE 120 Query: 121 SIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFDVQMAEIDFDPDTYTP 180 +IAKPV+K AVTVRE ALVPRV QQAFHLMRSGRPGPVL+DLPFDVQ+AEI+FDPD Y P Sbjct: 121 AIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEP 180 Query: 181 LPVYRPAATRAQIEKAFDMLNAAQRPLLTIGGGVVNADAAALAVEFAELTGVPVIPTLMA 240 LPVY+PAA+R QIEKA +ML ++RP++ GGGV+NADAA L +FAELT VPVIPTLM Sbjct: 181 LPVYKPAASRVQIEKALEMLIQSERPVIVAGGGVINADAAPLLQQFAELTNVPVIPTLMG 240 Query: 241 WGAIADDHPQMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSIDVFTKGRTFVH 300 WG I DDHP MAGMVGLQT+HRYGNATLLASD V GIGNR+ANRHTGS++ +T+GR +H Sbjct: 241 WGCIPDDHPLMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTQGRKIIH 300 Query: 301 VDIEPTQIGRVFGPDYGIVSDAGAALKLFVEVAKEWKTAGRLPDRSAWLAECQQRKKSLQ 360 +DIEPTQIGRV PD GIVSDA AAL L ++VA+E + AGRLP R W+ ECQQRK++L Sbjct: 301 IDIEPTQIGRVLCPDLGIVSDAKAALTLLIDVAQEMQKAGRLPCRKTWVDECQQRKRTLL 360 Query: 361 RRTHFNDTPVKPQRVYEEMNRAFGRETCYVATIGLSQIAAAQFLHVYRDRHWINCGQAGP 420 R+THF++ PVKPQRVYEEMN+AFGR+ CYV TIGLSQIAAAQ LHV++DRHWINCGQAGP Sbjct: 361 RKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGP 420 Query: 421 LGWTIPAALGVVAADPQKKVVAISGDYDFQFMIEELAVGAQFKLPYLHVLVNNSYLGLIR 480 LGWTIPAALGV AADPQ+ VVAISGD+DFQF+IEELAVGAQF +PY+HVLVNN+YLGLIR Sbjct: 421 LGWTIPAALGVCAADPQRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIR 480 Query: 481 QAQRGFEMDYCVQLAFENINAPELNGYGVDHVAVVEGLGCKAIRVTDPNAIQDAFAQAQR 540 Q+QR F+MDYCVQLAFENIN+ E+NGYGVDHV V EGLGCKAIRV P I AF QA+ Sbjct: 481 QSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKA 540 Query: 541 WMAEYRVPVVVEIILERVTNIAMGTEIDAINEFEPLAERADDAPTAISLL 590 MA+YRVPVVVE+ILERVTNI+MG+E+D + EFE +A+ A DAPT + Sbjct: 541 LMAQYRVPVVVEVILERVTNISMGSELDNVTEFEEVADSAKDAPTETCFM 590 >gcl [R] COG3960 Glyoxylate carboligase Eco Escherichia coli K12 Length = 593 Score = 967 bits (2499), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/590 (77%), Positives = 517/590 (87%) Query: 1 MAKMRAVDAAVHVLVKEGCLQAFGVPGAAINPFYSALKKHGGISHILARHVEGASHMAEG 60 MAKMRAVDAA++VL KEG AFGVPGAAINPFYSA++KHGGI HILARHVEGASHMAEG Sbjct: 1 MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEG 60 Query: 61 YTRAKAGNIGLCIGTSGPAGTDMITGLYSAQADSIPILCVTGQAPRARLYKEDFQAVDIE 120 YTRA AGNIG+C+GTSGPAGTDMIT LYSA ADSIPILC+TGQAPRARL+KEDFQAVDIE Sbjct: 61 YTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIE 120 Query: 121 SIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFDVQMAEIDFDPDTYTP 180 +IAKPV+K AVTVRE ALVPRV QQAFHLMRSGRPGPVL+DLPFDVQ+AEI+FDPD Y P Sbjct: 121 AIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEP 180 Query: 181 LPVYRPAATRAQIEKAFDMLNAAQRPLLTIGGGVVNADAAALAVEFAELTGVPVIPTLMA 240 LPVY+PAA+R QIEKA +ML A+RP++ GGGV+NADAAAL +FAELT VPVIPTLM Sbjct: 181 LPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMG 240 Query: 241 WGAIADDHPQMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSIDVFTKGRTFVH 300 WG I DDH MAGMVGLQT+HRYGNATLLASD V GIGNR+ANRHTGS++ +T+GR VH Sbjct: 241 WGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVH 300 Query: 301 VDIEPTQIGRVFGPDYGIVSDAGAALKLFVEVAKEWKTAGRLPDRSAWLAECQQRKKSLQ 360 +DIEPTQIGRV PD GIVSDA AAL L VEVA+E + AGRLP R W+A+CQQRK++L Sbjct: 301 IDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLL 360 Query: 361 RRTHFNDTPVKPQRVYEEMNRAFGRETCYVATIGLSQIAAAQFLHVYRDRHWINCGQAGP 420 R+THF++ PVKPQRVYEEMN+AFGR+ CYV TIGLSQIAAAQ LHV++DRHWINCGQAGP Sbjct: 361 RKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGP 420 Query: 421 LGWTIPAALGVVAADPQKKVVAISGDYDFQFMIEELAVGAQFKLPYLHVLVNNSYLGLIR 480 LGWTIPAALGV AADP++ VVAISGD+DFQF+IEELAVGAQF +PY+HVLVNN+YLGLIR Sbjct: 421 LGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIR 480 Query: 481 QAQRGFEMDYCVQLAFENINAPELNGYGVDHVAVVEGLGCKAIRVTDPNAIQDAFAQAQR 540 Q+QR F+MDYCVQLAFENIN+ E+NGYGVDHV V EGLGCKAIRV P I AF QA+ Sbjct: 481 QSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKA 540 Query: 541 WMAEYRVPVVVEIILERVTNIAMGTEIDAINEFEPLAERADDAPTAISLL 590 MA+YRVPVVVE+ILERVTNI+MG+E+D + EFE +A+ A DAPT + Sbjct: 541 LMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFM 590 >Zgcl [R] COG3960 Glyoxylate carboligase EcZ Escherichia coli O157:H7 EDL933 Length = 593 Score = 967 bits (2499), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/590 (77%), Positives = 517/590 (87%) Query: 1 MAKMRAVDAAVHVLVKEGCLQAFGVPGAAINPFYSALKKHGGISHILARHVEGASHMAEG 60 MAKMRAVDAA++VL KEG AFGVPGAAINPFYSA++KHGGI HILARHVEGASHMAEG Sbjct: 1 MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEG 60 Query: 61 YTRAKAGNIGLCIGTSGPAGTDMITGLYSAQADSIPILCVTGQAPRARLYKEDFQAVDIE 120 YTRA AGNIG+C+GTSGPAGTDMIT LYSA ADSIPILC+TGQAPRARL+KEDFQAVDIE Sbjct: 61 YTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIE 120 Query: 121 SIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFDVQMAEIDFDPDTYTP 180 +IAKPV+K AVTVRE ALVPRV QQAFHLMRSGRPGPVL+DLPFDVQ+AEI+FDPD Y P Sbjct: 121 AIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEP 180 Query: 181 LPVYRPAATRAQIEKAFDMLNAAQRPLLTIGGGVVNADAAALAVEFAELTGVPVIPTLMA 240 LPVY+PAA+R QIEKA +ML A+RP++ GGGV+NADAAAL +FAELT VPVIPTLM Sbjct: 181 LPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMG 240 Query: 241 WGAIADDHPQMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSIDVFTKGRTFVH 300 WG I DDH MAGMVGLQT+HRYGNATLLASD V GIGNR+ANRHTGS++ +T+GR VH Sbjct: 241 WGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVH 300 Query: 301 VDIEPTQIGRVFGPDYGIVSDAGAALKLFVEVAKEWKTAGRLPDRSAWLAECQQRKKSLQ 360 +DIEPTQIGRV PD GIVSDA AAL L VEVA+E + AGRLP R W+A+CQQRK++L Sbjct: 301 IDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLL 360 Query: 361 RRTHFNDTPVKPQRVYEEMNRAFGRETCYVATIGLSQIAAAQFLHVYRDRHWINCGQAGP 420 R+THF++ PVKPQRVYEEMN+AFGR+ CYV TIGLSQIAAAQ LHV++DRHWINCGQAGP Sbjct: 361 RKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGP 420 Query: 421 LGWTIPAALGVVAADPQKKVVAISGDYDFQFMIEELAVGAQFKLPYLHVLVNNSYLGLIR 480 LGWTIPAALGV AADP++ VVAISGD+DFQF+IEELAVGAQF +PY+HVLVNN+YLGLIR Sbjct: 421 LGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIR 480 Query: 481 QAQRGFEMDYCVQLAFENINAPELNGYGVDHVAVVEGLGCKAIRVTDPNAIQDAFAQAQR 540 Q+QR F+MDYCVQLAFENIN+ E+NGYGVDHV V EGLGCKAIRV P I AF QA+ Sbjct: 481 QSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKA 540 Query: 541 WMAEYRVPVVVEIILERVTNIAMGTEIDAINEFEPLAERADDAPTAISLL 590 MA+YRVPVVVE+ILERVTNI+MG+E+D + EFE +A+ A DAPT + Sbjct: 541 LMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFM 590 >ECs0568 [R] COG3960 Glyoxylate carboligase Ecs Escherichia coli O157:H7 Length = 593 Score = 967 bits (2499), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/590 (77%), Positives = 517/590 (87%) Query: 1 MAKMRAVDAAVHVLVKEGCLQAFGVPGAAINPFYSALKKHGGISHILARHVEGASHMAEG 60 MAKMRAVDAA++VL KEG AFGVPGAAINPFYSA++KHGGI HILARHVEGASHMAEG Sbjct: 1 MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEG 60 Query: 61 YTRAKAGNIGLCIGTSGPAGTDMITGLYSAQADSIPILCVTGQAPRARLYKEDFQAVDIE 120 YTRA AGNIG+C+GTSGPAGTDMIT LYSA ADSIPILC+TGQAPRARL+KEDFQAVDIE Sbjct: 61 YTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIE 120 Query: 121 SIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFDVQMAEIDFDPDTYTP 180 +IAKPV+K AVTVRE ALVPRV QQAFHLMRSGRPGPVL+DLPFDVQ+AEI+FDPD Y P Sbjct: 121 AIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEP 180 Query: 181 LPVYRPAATRAQIEKAFDMLNAAQRPLLTIGGGVVNADAAALAVEFAELTGVPVIPTLMA 240 LPVY+PAA+R QIEKA +ML A+RP++ GGGV+NADAAAL +FAELT VPVIPTLM Sbjct: 181 LPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMG 240 Query: 241 WGAIADDHPQMAGMVGLQTSHRYGNATLLASDFVLGIGNRWANRHTGSIDVFTKGRTFVH 300 WG I DDH MAGMVGLQT+HRYGNATLLASD V GIGNR+ANRHTGS++ +T+GR VH Sbjct: 241 WGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVH 300 Query: 301 VDIEPTQIGRVFGPDYGIVSDAGAALKLFVEVAKEWKTAGRLPDRSAWLAECQQRKKSLQ 360 +DIEPTQIGRV PD GIVSDA AAL L VEVA+E + AGRLP R W+A+CQQRK++L Sbjct: 301 IDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLL 360 Query: 361 RRTHFNDTPVKPQRVYEEMNRAFGRETCYVATIGLSQIAAAQFLHVYRDRHWINCGQAGP 420 R+THF++ PVKPQRVYEEMN+AFGR+ CYV TIGLSQIAAAQ LHV++DRHWINCGQAGP Sbjct: 361 RKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGP 420 Query: 421 LGWTIPAALGVVAADPQKKVVAISGDYDFQFMIEELAVGAQFKLPYLHVLVNNSYLGLIR 480 LGWTIPAALGV AADP++ VVAISGD+DFQF+IEELAVGAQF +PY+HVLVNN+YLGLIR Sbjct: 421 LGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIR 480 Query: 481 QAQRGFEMDYCVQLAFENINAPELNGYGVDHVAVVEGLGCKAIRVTDPNAIQDAFAQAQR 540 Q+QR F+MDYCVQLAFENIN+ E+NGYGVDHV V EGLGCKAIRV P I AF QA+ Sbjct: 481 QSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKA 540 Query: 541 WMAEYRVPVVVEIILERVTNIAMGTEIDAINEFEPLAERADDAPTAISLL 590 MA+YRVPVVVE+ILERVTNI+MG+E+D + EFE +A+ A DAPT + Sbjct: 541 LMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFM 590