BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0300.p (378 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1148 Non COG 390 e-108 PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudom... 250 4e-66 YPO1632 [S] COG2850 Uncharacterized conserved protein Ype Yersin... 205 1e-52 STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmon... 205 1e-52 ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherich... 204 2e-52 >RSc1148 Non COG Length = 409 Score = 390 bits (1001), Expect = e-108, Method: Compositional matrix adjust. Identities = 206/388 (53%), Positives = 263/388 (67%), Gaps = 14/388 (3%) Query: 1 MATMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIP-----GFTAPLPRQELFDLARRDDV 55 +A + LLGG++P F+R +W KKPLLIR A+ PL L LARR+DV Sbjct: 17 LAAGRPAQLLGGLSPRDFMRTHWQKKPLLIRQALSPEDMRALHFPLSPDALIKLARREDV 76 Query: 56 ESRLITHRTDGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDAR 113 ESRLI W HGPFN+ LP K + WTLLVQGVNL PA DAL+++FRF+PDAR Sbjct: 77 ESRLIAQTRGRWTFNHGPFNERPLPSRKARNWTLLVQGVNLVEPAVDALMQRFRFIPDAR 136 Query: 114 LDDLMISYATDGGGVGPHFDSYDVFLLQAHGQRRWRISAQDDLTLEEGVPLKILSNFEAE 173 LDD+MIS+ATDGGGVGPHFDSYDVFLLQAHG+RRWRIS+Q+DLTL +PLKIL+NF E Sbjct: 137 LDDVMISFATDGGGVGPHFDSYDVFLLQAHGRRRWRISSQNDLTLVPDLPLKILANFTPE 196 Query: 174 QEFVLEPGDMLYLPPQYAHDGVAIGECMTYSVGFRSPAYQELGESFLEFMMDTI----DL 229 +EF+LEPGDMLYLPP YAHDGVA G+CMTYSVGFRSP+Y+EL FL F+ T+ D Sbjct: 197 EEFILEPGDMLYLPPHYAHDGVAEGDCMTYSVGFRSPSYRELAGHFLGFLSQTLEDNPDF 256 Query: 230 SGRYEDPDLKATAKPAELPLDMVARIRDELNKIRFTDDDITIFLGEHLSEPKPSVFFEAR 289 GRY DP+ K +P ELP MV + +LN +R+T + + F G +L+EPK V F + Sbjct: 257 EGRYTDPEQKPVERPGELPTAMVRALAQKLNALRWTPELVGEFFGAYLTEPKDHVEFVTQ 316 Query: 290 TEELSFARFFQGAKKRGLALHRKTRMLYRGSHVFINGESFQVNRGDKAILARLADSRVLE 349 LS ARF A+K G+ L +T+ LY +ING++F+ + A L+ L+D R Sbjct: 317 P-RLSLARFTARARKEGIVLDARTQALYDAQRFWINGDTFEPSDTLLAWLSALSDQRGAS 375 Query: 350 KSDLDLASE--DLLEALHQWHESGWLDI 375 +D A++ DL++ LH W+E GWL + Sbjct: 376 AEAVDAAADLPDLMDTLHAWYEEGWLQL 403 >PA2630 [S] COG2850 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 389 Score = 250 bits (639), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 149/366 (40%), Positives = 212/366 (57%), Gaps = 17/366 (4%) Query: 1 MATMKKLDLLGGITPAQFLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDDVESRLI 60 M L LLGG+T A+FLRDYW +KPLL+R AIP F +PL EL L+ + VESR++ Sbjct: 1 MNADTPLQLLGGLTAAEFLRDYWQRKPLLVRQAIPDFESPLSADELAGLSLEESVESRIV 60 Query: 61 -THRTDGWDMQHGPFNK--LPPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDL 117 H W+M+ GPF + L ++ WTLLVQ V+ P LL QFRF+P R+DD+ Sbjct: 61 LEHGKTPWEMRRGPFQEEDYQHLPEQDWTLLVQAVDQFVPEVAQLLEQFRFLPSWRIDDV 120 Query: 118 MISYATDGGGVGPHFDSYDVFLLQAHGQRRWRIS--AQDDLTLEEGVPLKILSNFEAEQE 175 MISYA GGGVGPHFD+YDVFLLQ HG+RRW++ D L E L+IL++FE E Sbjct: 121 MISYAAPGGGVGPHFDNYDVFLLQGHGRRRWKVGQMCSSDSPLREHADLRILADFEQSDE 180 Query: 176 FVLEPGDMLYLPPQYAHDGVAIGECMTYSVGFRSPAYQELGESFLEFMMDTIDLSGRYED 235 +VLEPGDMLYLPP+ AH G+A ECMTYS+GFR+P+ E+ F +F+ + RY D Sbjct: 181 WVLEPGDMLYLPPRLAHYGIAEDECMTYSIGFRAPSAAEVLTHFTDFLGQFLSDEERYTD 240 Query: 236 PDLKATA-KPAELPLDMVARIRDELNKIRFTDDDITIFLGEHLSEPK-PSVFFEARTEEL 293 L+ P ++ D + R++ + + + + + G+ ++EP+ P + EE+ Sbjct: 241 AGLQPVGDDPHQIQRDALERLQGLIQEHMSDERLLLTWFGQFMTEPRYPEL---VAGEEI 297 Query: 294 SFARFFQGAKKRGLALHRK--TRMLYR----GSHVFINGESFQVNRGDKAILARLADSRV 347 F GA + G L R R+ + G +F +G+S + K +L + + Sbjct: 298 PEEELF-GALEDGALLVRNPSARLAWSEIDIGLVLFASGQSVLLPGQLKELLKLVCSADA 356 Query: 348 LEKSDL 353 L +L Sbjct: 357 LHLENL 362 >YPO1632 [S] COG2850 Uncharacterized conserved protein Ype Yersinia pestis Length = 373 Score = 205 bits (522), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 4/313 (1%) Query: 18 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDDVESRLITHRTDGWDMQHGPFNKL 77 FL+ YW K+P++++ F PL EL LA ++V+SRL++H W + HGPF Sbjct: 12 FLQRYWQKRPVILKRGFKNFIDPLSPDELAGLAMENEVDSRLVSHEDGRWHVSHGPFESF 71 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 137 L + W+LLVQ V+ H A AL+R FR + D R+DDLMIS++ GGGVGPHFD YDV Sbjct: 72 DHLGENNWSLLVQAVDHWHEPAAALMRPFRPLSDWRMDDLMISFSVPGGGVGPHFDQYDV 131 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP-LKILSNFEAEQEFVLEPGDMLYLPPQYAHDGVA 196 F++Q G+RRWR+ + ++ P L + F+A + +EPGD+LY+PP + H+G + Sbjct: 132 FIIQGSGRRRWRVGEKTEMKQHCPHPDLLQVGPFDAIIDEEMEPGDILYIPPGFPHEGYS 191 Query: 197 IGECMTYSVGFRSPAYQELGESFLEFMMDTIDLSGRYEDPDLKATAKPAELPLDMVARIR 256 + + YSVGFR+P+ +EL F ++++ S RY DPDL+ PAE+ V ++R Sbjct: 192 LENALNYSVGFRAPSGRELVSGFADYVLARELGSYRYSDPDLQLREHPAEVLPSEVDKLR 251 Query: 257 DELNKIRFTDDDITIFLGEHLSEPKPSVFFEARTEELSFARFFQGAKKRGLALHRKT--R 314 + + + + GE +S+ + + ++ K+G L R + R Sbjct: 252 TMMLDLVQQPEHFQNWFGEFISQSRHELDIAPPEPPYQTGDIYE-LLKQGDELQRLSGLR 310 Query: 315 MLYRGSHVFINGE 327 +L G F NGE Sbjct: 311 VLRVGDRCFANGE 323 >STM1229 [S] COG2850 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 373 Score = 205 bits (522), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 122/347 (35%), Positives = 186/347 (53%), Gaps = 10/347 (2%) Query: 18 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDDVESRLITHRTDGWDMQHGPFNKL 77 FL +W K+P++++ F PL EL LA +++SRL++H+ W + HGPF Sbjct: 12 FLERHWQKRPVVLKRGFSNFIDPLSPDELAGLAMESEIDSRLVSHQDGKWQVSHGPFESY 71 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 137 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 72 DHLGESNWSLLVQAVNHWHEPTAALMRPFRALPDWRIDDLMISFSVPGGGVGPHLDQYDV 131 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSNFEAEQEFVLEPGDMLYLPPQYAHDG 194 F++Q G+RRWR+ + L + + P L + FEA + LEPGD+LY+PP + H+G Sbjct: 132 FIIQGTGRRRWRVG--EKLQMRQHCPHPDLLQVEPFEAIIDEELEPGDILYIPPGFPHEG 189 Query: 195 VAIGECMTYSVGFRSPAYQELGESFLEFMMDTIDLSGRYEDPDLKATAKPAELPLDMVAR 254 A+ M YSVGFR+P +EL F ++++ + Y DPD+ + PA++ + + Sbjct: 190 YALENAMNYSVGFRAPNSRELISGFADYVLQRELGNTYYSDPDMPSRKHPADILPQEMDK 249 Query: 255 IRDELNKIRFTDDDITIFLGEHLSEPKPSVFFEARTEELSFARFFQGAKKRGLALHR--K 312 +R+ + + +LGE LS+ + + + A K+G L R Sbjct: 250 LRNMMLDLINQPAHFQQWLGEFLSQSRHELDIAPPEPPYQPDEIYD-ALKQGEVLVRLGG 308 Query: 313 TRMLYRGSHVFINGESFQVNRGDKAILARLADSRVLEKSDLDLASED 359 R+L G V+ NGE +++ + L LA L + A ED Sbjct: 309 LRVLRIGDEVYANGE--KIDSPHRPALEALASHIALTAENFGDALED 353 >ycfD [S] COG2850 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 376 Score = 204 bits (520), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 121/347 (34%), Positives = 188/347 (54%), Gaps = 10/347 (2%) Query: 18 FLRDYWHKKPLLIRNAIPGFTAPLPRQELFDLARRDDVESRLITHRTDGWDMQHGPFNKL 77 FL +W K+P++++ F P+ EL LA +V+SRL++H+ W + HGPF Sbjct: 15 FLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESY 74 Query: 78 PPLKQKAWTLLVQGVNLHHPAADALLRQFRFVPDARLDDLMISYATDGGGVGPHFDSYDV 137 L + W+LLVQ VN H AL+R FR +PD R+DDLMIS++ GGGVGPH D YDV Sbjct: 75 DHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDV 134 Query: 138 FLLQAHGQRRWRISAQDDLTLEEGVP---LKILSNFEAEQEFVLEPGDMLYLPPQYAHDG 194 F++Q G+RRWR+ + L +++ P L + FEA + LEPGD+LY+PP + H+G Sbjct: 135 FIIQGTGRRRWRVGEK--LQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEG 192 Query: 195 VAIGECMTYSVGFRSPAYQELGESFLEFMMDTIDLSGRYEDPDLKATAKPAELPLDMVAR 254 A+ M YSVGFR+P +EL F ++++ Y DPD+ A PA++ + + Sbjct: 193 YALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDK 252 Query: 255 IRDELNKIRFTDDDITIFLGEHLSEPKPSVFFEARTEELSFARFFQGAKKRGLALHR--K 312 +R+ + ++ + + GE +S+ + + + A K+G L R Sbjct: 253 LREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYD-ALKQGEVLVRLGG 311 Query: 313 TRMLYRGSHVFINGESFQVNRGDKAILARLADSRVLEKSDLDLASED 359 R+L G V+ NGE +++ + L LA + L + A ED Sbjct: 312 LRVLRIGDDVYANGE--KIDSPHRPALDALASNIALTAENFGDALED 356