BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0292.p (269 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA1031 [O] COG0501 Zn-dependent protease with chaperone functio... 276 5e-74 NMB0822 [O] COG0501 Zn-dependent protease with chaperone functio... 275 6e-74 PA2830 [O] COG0501 Zn-dependent protease with chaperone function... 268 1e-71 XF2625 [O] COG0501 Zn-dependent protease with chaperone function... 264 2e-70 PM0468 [O] COG0501 Zn-dependent protease with chaperone function... 249 4e-66 >NMA1031 [O] COG0501 Zn-dependent protease with chaperone function NmA Neisseria meningitidis Z2491 Length = 279 Score = 276 bits (705), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 150/250 (60%), Positives = 188/250 (75%), Gaps = 11/250 (4%) Query: 1 MKRILLFIATNIAVLVVMSVILSLLGVDRFLTRSGLNLPMLMVFSLVVGFTGSIISLLMS 60 MKRI LF+ATNIAVLVV++++L++LG++ ++ G L+ +S VVGFTGSIISLLMS Sbjct: 1 MKRIFLFLATNIAVLVVINIVLAVLGIN---SQGGTG--SLLAYSAVVGFTGSIISLLMS 55 Query: 61 KSMAKWSTGARVIETPMNGTEAWLLQTVGKLAQRAGIGMPEVAVYDG-EPNAFATGAFRD 119 K +AK S GA VI+TP EAWLL TV A++ + PEVA+Y EPNAFATGA R+ Sbjct: 56 KFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRN 115 Query: 120 SALVAVSTGLLQGMTQDEVEAVLGHEVAHIANGDMVTMTLIQGVVNTFVVFLSRVVGYFV 179 S+L+AVSTGLL MT+DEVEAVL HE+AH+ NGDMVT+TLIQGVVNTFVVFLSR++ + Sbjct: 116 SSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRIIANLI 175 Query: 180 DSALRRNNESSGPGIGYMVTVMVCQIVFGIGASIIVAWFSRHREFRADAGAARLLGTPQP 239 RNN+ S Y + MV QI+FG AS+IV WFSR RE+RADAGAA+L+G P+ Sbjct: 176 ----ARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPK- 230 Query: 240 MINALARLGG 249 MI+AL RL G Sbjct: 231 MISALQRLKG 240 >NMB0822 [O] COG0501 Zn-dependent protease with chaperone function Nme Neisseria meningitidis MC58 Length = 347 Score = 275 bits (704), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 150/250 (60%), Positives = 188/250 (75%), Gaps = 11/250 (4%) Query: 1 MKRILLFIATNIAVLVVMSVILSLLGVDRFLTRSGLNLPMLMVFSLVVGFTGSIISLLMS 60 +KRI LF+ATNIAVLVV++++L++LG++ +R G L+ +S VVGFTGSIISLLMS Sbjct: 69 VKRIFLFLATNIAVLVVINIVLAVLGIN---SRGGTG--SLLAYSAVVGFTGSIISLLMS 123 Query: 61 KSMAKWSTGARVIETPMNGTEAWLLQTVGKLAQRAGIGMPEVAVYDG-EPNAFATGAFRD 119 K +AK S GA VI+TP EAWLL TV A++ + PEVA+Y EPNAFATGA R+ Sbjct: 124 KFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHSPEPNAFATGASRN 183 Query: 120 SALVAVSTGLLQGMTQDEVEAVLGHEVAHIANGDMVTMTLIQGVVNTFVVFLSRVVGYFV 179 S+L+AVSTGLL MT+DEVEAVL HE+AH+ NGDMVT+TLIQGVVNTFVVFLSR++ + Sbjct: 184 SSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVVNTFVVFLSRIIANLI 243 Query: 180 DSALRRNNESSGPGIGYMVTVMVCQIVFGIGASIIVAWFSRHREFRADAGAARLLGTPQP 239 RNN+ S Y + MV QI+FG AS+IV WFSR RE+RADAGAA+L+G P+ Sbjct: 244 ----ARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRADAGAAKLVGAPK- 298 Query: 240 MINALARLGG 249 MI+AL RL G Sbjct: 299 MISALQRLKG 308 >PA2830 [O] COG0501 Zn-dependent protease with chaperone function Pae Pseudomonas aeruginosa Length = 291 Score = 268 bits (685), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 146/248 (58%), Positives = 177/248 (71%), Gaps = 7/248 (2%) Query: 1 MKRILLFIATNIAVLVVMSVILSLLGVDRFLTRSGLNLPMLMVFSLVVGFTGSIISLLMS 60 M RILLF+ATN+AVLV+ S+ L LLGVDRF +G N L+VF V GF GS++SL +S Sbjct: 1 MMRILLFLATNLAVLVIASITLKLLGVDRF---TGQNYGSLLVFCAVFGFAGSLVSLFIS 57 Query: 61 KSMAKWSTGARVIETPMNGTEAWLLQTVGKLAQRAGIGMPEVAVYDG-EPNAFATGAFRD 119 K MAK STG VI P E WLLQTV +L++ AGI MPEV ++ E NAFATG ++ Sbjct: 58 KWMAKMSTGTEVISQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNKN 117 Query: 120 SALVAVSTGLLQGMTQDEVEAVLGHEVAHIANGDMVTMTLIQGVVNTFVVFLSRVVGYFV 179 ALVAVS GLL+ + DEV+AVL HE+ H+ANGDMVT+ LIQGVVNTFV+F +R+ G FV Sbjct: 118 DALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFV 177 Query: 180 DSALRRNNESSGPGIGYMVTVMVCQIVFGIGASIIVAWFSRHREFRADAGAARLLGTPQP 239 D A+ +N + GPGIGY V + ++V GI ASIIV WFSR REFRADA A L GT Sbjct: 178 DKAILKNED--GPGIGYFVATIFAELVLGILASIIVMWFSRRREFRADAAGAHLAGT-GA 234 Query: 240 MINALARL 247 MI AL RL Sbjct: 235 MIAALQRL 242 >XF2625 [O] COG0501 Zn-dependent protease with chaperone function Xfa Xylella fastidiosa 9a5c Length = 289 Score = 264 bits (674), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 142/249 (57%), Positives = 184/249 (73%), Gaps = 9/249 (3%) Query: 1 MKRILLFIATNIAVLVVMSVILSLLGVDRFLTRSGLNLPMLMVFSLVVGFTGSIISLLMS 60 + RI+LF TN+AVL++ S+++SLLGV+ + L+V +L+ GF GS ISLLMS Sbjct: 2 LTRIVLFAITNLAVLILASIVMSLLGVNP------TQMSGLLVMALIFGFAGSFISLLMS 55 Query: 61 KSMAKWSTGARVIETPMNGTEAWLLQTVGKLAQRAGIGMPEVAVYDG-EPNAFATGAFRD 119 K++AK +TGA VI+ P N +E WLL TV + A+ GIG PE+A+Y+G E NAFATGA R+ Sbjct: 56 KAIAKRTTGAYVIDQPRNLSERWLLDTVSRQAEIVGIGRPEIAIYEGVEINAFATGADRN 115 Query: 120 SALVAVSTGLLQGMTQDEVEAVLGHEVAHIANGDMVTMTLIQGVVNTFVVFLSRVVGYFV 179 +ALVAVSTGLLQ M+QDEVEAVLGHE+AH+ANGDMVTM L+QGV+NTFV+ L+RVVG F+ Sbjct: 116 NALVAVSTGLLQNMSQDEVEAVLGHEIAHVANGDMVTMALLQGVLNTFVIVLARVVGGFI 175 Query: 180 DSALRRNNESSGPGIGYMVTVMVCQIVFGIGASIIVAWFSRHREFRADAGAARLLGTPQP 239 DS L N G+ Y V+V +++FG+ A++I WFSR REFRAD G A L G + Sbjct: 176 DSLL-SGNRGGARGVAYYAIVLVLELLFGLFATMITMWFSRRREFRADEGGAYLAGRNK- 233 Query: 240 MINALARLG 248 MI AL RLG Sbjct: 234 MIAALERLG 242 >PM0468 [O] COG0501 Zn-dependent protease with chaperone function Pmu Pasteurella multocida Length = 286 Score = 249 bits (636), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 138/248 (55%), Positives = 181/248 (72%), Gaps = 12/248 (4%) Query: 1 MKRILLFIATNIAVLVVMSVILSLLGVDRFLTRSGLNLPMLMVFSLVVGFTGSIISLLMS 60 M RILLF+ATN+AVLVV ++ILSL G+ + L++ + + GF+GS+ISL +S Sbjct: 1 MMRILLFLATNMAVLVVFNIILSLTGIQ------AQDATGLLLMAALFGFSGSLISLFLS 54 Query: 61 KSMAKWSTGARVIETPMNGTEAWLLQTVGKLAQRAGIGMPEVAVYDGEP-NAFATGAFRD 119 K+MA + GA VI+ P N E WL+ TV A+RA + MP+VA+Y E NAFATG ++ Sbjct: 55 KTMALRAVGAEVIKQPRNDMERWLVNTVRSQAERANLPMPDVAIYHSEDVNAFATGPSKN 114 Query: 120 SALVAVSTGLLQGMTQDEVEAVLGHEVAHIANGDMVTMTLIQGVVNTFVVFLSRVVGYFV 179 ++LVAVSTGLL+ MTQDE EAVL HEVAHI NGDMVTMTL+QGV+NTFV+F+SR++ V Sbjct: 115 NSLVAVSTGLLRAMTQDEAEAVLAHEVAHIKNGDMVTMTLLQGVLNTFVIFVSRMIAKVV 174 Query: 180 DSALRRNNESSGPGIGYMVTVMVCQIVFGIGASIIVAWFSRHREFRADAGAARLLGTPQP 239 S R+ ESS GI ++V+ MV +I+FG AS+I WFSR+REFRADAG+A+L+G Sbjct: 175 SS--NRDGESS-TGIYFLVS-MVLEILFGFLASMIAMWFSRYREFRADAGSAKLVGK-HK 229 Query: 240 MINALARL 247 MI AL RL Sbjct: 230 MIAALQRL 237