BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0291.p (247 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1140 Non COG 318 5e-87 NMB1824 [R] COG0613 Predicted metal-dependent phosphoesterases (... 207 2e-53 NMA0635 [R] COG0613 Predicted metal-dependent phosphoesterases (... 205 7e-53 YPO2211 [R] COG0613 Predicted metal-dependent phosphoesterases (... 184 2e-46 STM1721 [R] COG0613 Predicted metal-dependent phosphoesterases (... 176 3e-44 >RSc1140 Non COG Length = 286 Score = 318 bits (816), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 164/277 (59%), Positives = 191/277 (68%), Gaps = 33/277 (11%) Query: 2 SELKFDLHCHSNVSDGL---------------------------------RAARALGMEH 28 + + DLHCHS VSDGL AA +LGM++ Sbjct: 8 APINADLHCHSTVSDGLLAPREVAARAAAHGVTLWALTDHDEVGGQAAAREAAESLGMDY 67 Query: 29 VAGVEISVTWAGHTVHIVGLRIDETNQALVDGLAATRNGRERRAREIAEALDRHGICGAY 88 +AGVEISVTWAG T+HIVGL ID + ALV GLA TR+GR RA ++AEAL + GI GAY Sbjct: 68 LAGVEISVTWAGRTLHIVGLGIDPDDAALVQGLARTRSGRCARAEDMAEALGKLGIHGAY 127 Query: 89 EGALKHVGNPDLISRTHFARYLVECGTCCDTKEVFANYLTEGKPGYVPHRWATLEESVRW 148 EGAL + GNPD+ISRTHFAR+LVE G C D EVF YL EGKPG+VPHRW+ L +++ W Sbjct: 128 EGALSYAGNPDMISRTHFARFLVEHGHCRDIAEVFDRYLGEGKPGFVPHRWSRLADAIGW 187 Query: 149 IRGAGGVAVIAHPGRYKYTQTQFGALFDEFKQLGGEAIEVNTGSHTPEQYQEYAQVARSY 208 IRGAGGVAV+AHPGRY T + GALFDEFK LGGE +EV TGSHTP+QY YA VAR Y Sbjct: 188 IRGAGGVAVMAHPGRYTLTLLEHGALFDEFKDLGGEGVEVVTGSHTPDQYACYADVARRY 247 Query: 209 GFLASMGSDFHGPGESRMDLGGLPPLPTGVKPVWHDW 245 G LAS GSDFHGPGE R++LG LPPLP + PVW W Sbjct: 248 GLLASRGSDFHGPGEGRVELGELPPLPDNLTPVWSRW 284 >NMB1824 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) Nme Neisseria meningitidis MC58 Length = 278 Score = 207 bits (527), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 117/271 (43%), Positives = 151/271 (55%), Gaps = 34/271 (12%) Query: 6 FDLHCHSNVSDGLRA-----------------------------ARA----LGMEHVAGV 32 DLHCHS VSDG+ + ARA LG+ + GV Sbjct: 2 IDLHCHSTVSDGMLSPAEVVRLAHQNGCTLLALTDHDHTGGIAEARAEADKLGLRLINGV 61 Query: 33 EISVTWAGHTVHIVGLRIDETNQALVDGLAATRNGRERRAREIAEALDRHGICGAYEGAL 92 EISVTW G T+H+VGL DE ++ L + LA R GR +R IA L++ GI GAY+GAL Sbjct: 62 EISVTWRGRTIHVVGLDFDEQDENLQNLLAQVRKGRLKRLEAIAAKLEKKGIGGAYDGAL 121 Query: 93 KHVGNPDLISRTHFARYLVECGTCCDTKEVFANYLTEGKPGYVPHRWATLEESVRWIRGA 152 N +++SRTH A +L++ G + ++ F YL +GK V H WATLE+ V + GA Sbjct: 122 ALAANKEMVSRTHVAEFLIQAGHVKNKQQAFTKYLGDGKSCAVRHEWATLEDCVSAVNGA 181 Query: 153 GGVAVIAHPGRYKYTQTQFGALFDEFKQLGGEAIEVNTGSHTPEQYQEYAQVARSYGFLA 212 GG+AVIAHP RY + T LF+EFK LGG IEV++G+ YA +A +G LA Sbjct: 182 GGMAVIAHPMRYDLSATAKRNLFEEFKNLGGAGIEVHSGNCCKNDRLNYALLAERFGMLA 241 Query: 213 SMGSDFHGPGE-SRMDLGGLPPLPTGVKPVW 242 S GSDFH + S LG P LP KPVW Sbjct: 242 SAGSDFHRLNDFSGGILGACPELPENCKPVW 272 >NMA0635 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) NmA Neisseria meningitidis Z2491 Length = 278 Score = 205 bits (522), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 116/271 (42%), Positives = 151/271 (55%), Gaps = 34/271 (12%) Query: 6 FDLHCHSNVSDGLRA-----------------------------ARA----LGMEHVAGV 32 DLHCHS VSDG+ + ARA LG+ + GV Sbjct: 2 IDLHCHSTVSDGMLSPAEVVRLAHQNGCTLLALTDHDHTGGIAEARAEADRLGLRLINGV 61 Query: 33 EISVTWAGHTVHIVGLRIDETNQALVDGLAATRNGRERRAREIAEALDRHGICGAYEGAL 92 EISVTW G T+H+VGL DE ++ L + LA R GR +R IA L++ GI GAY+GAL Sbjct: 62 EISVTWRGRTIHVVGLDFDERDENLQNLLAQVRQGRLKRLEAIAAKLEKKGIGGAYDGAL 121 Query: 93 KHVGNPDLISRTHFARYLVECGTCCDTKEVFANYLTEGKPGYVPHRWATLEESVRWIRGA 152 N +++SRTH A +L++ G + ++ F YL +GK V H WATLE+ V + GA Sbjct: 122 ALAANKEMVSRTHVAEFLIQAGHVKNKQQAFIKYLGDGKSCAVRHEWATLEDCVSAVNGA 181 Query: 153 GGVAVIAHPGRYKYTQTQFGALFDEFKQLGGEAIEVNTGSHTPEQYQEYAQVARSYGFLA 212 GG+AVIAHP RY + T LF+EFK LGG IEV++G+ YA +A +G LA Sbjct: 182 GGMAVIAHPMRYDLSATAKRNLFEEFKNLGGAGIEVHSGNCCKNDRLNYALLAERFGMLA 241 Query: 213 SMGSDFHGPGE-SRMDLGGLPPLPTGVKPVW 242 S GSDFH + S LG P LP +PVW Sbjct: 242 SAGSDFHRLNDFSGGILGACPELPENCRPVW 272 >YPO2211 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) Ype Yersinia pestis Length = 299 Score = 184 bits (466), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 109/275 (39%), Positives = 145/275 (52%), Gaps = 37/275 (13%) Query: 6 FDLHCHSNVSDG--------LRAARA---------------------------LGMEHVA 30 +DLH H+ SDG +RAA+ L + + Sbjct: 17 YDLHSHTTASDGTLTPSELVIRAAQMRVGVLAITDHDTTAGLAEAAAAIEQHQLALRLIP 76 Query: 31 GVEISVTWAGHTVHIVGLRIDETNQALVDGLAATRNGRERRAREIAEALDRHGICGAYEG 90 GVEIS W H +HIVGL ID + +L L A R +RA+EI+ L++ I GA+EG Sbjct: 77 GVEISTLWENHEIHIVGLGIDVQHVSLRTLLEAQSEHRYQRAQEISTRLEKARIVGAWEG 136 Query: 91 ALKHVGNPDLISRTHFARYLVECGTCCDTKEVFANYLTEGKPGYVPHRWATLEESVRWIR 150 A + N ++R HFARYLVE G + +VF YL +GK GYVP +W T+E+++ I+ Sbjct: 137 A-NRLANGGQVTRGHFARYLVELGLASNVGQVFKKYLAKGKTGYVPAQWCTIEQAIDAIK 195 Query: 151 GAGGVAVIAHPGRYKYTQTQFGALFDEFKQLGGEAIEVNTGSHTPEQYQEYAQVARSYGF 210 +GG AV+AHPGRY T L F + GG+A+EV P + Q AR Y Sbjct: 196 QSGGQAVLAHPGRYDLTAKWLKRLLAHFAEHGGDAMEVAQCQQAPHERALLGQYARDYHL 255 Query: 211 LASMGSDFHGPGESRMDLGGLPPLPTGVKPVWHDW 245 LAS GSDFH P S ++LG LP GV+PVW DW Sbjct: 256 LASQGSDFHQPC-SWIELGRKLWLPAGVEPVWRDW 289 >STM1721 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) Sty Salmonella typhimurium LT2 Length = 293 Score = 176 bits (447), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 106/275 (38%), Positives = 142/275 (51%), Gaps = 37/275 (13%) Query: 6 FDLHCHSNVSDGLR-----------------------------AAR------ALGMEHVA 30 +DLH H+ SDGL AAR L + + Sbjct: 14 YDLHSHTTASDGLLTPETLVHRAVEMRVGTLAITDHDTTAAIPAAREEISRSGLALNLIP 73 Query: 31 GVEISVTWAGHTVHIVGLRIDETNQALVDGLAATRNGRERRAREIAEALDRHGICGAYEG 90 GVEIS W H +HIVGL ID + A+ D LA R+ R R IAE L++ I GA+EG Sbjct: 74 GVEISTVWENHEIHIVGLNIDIAHPAMRDFLAQQTERRQARGRLIAERLEKAHIPGAWEG 133 Query: 91 ALKHVGNPDLISRTHFARYLVECGTCCDTKEVFANYLTEGKPGYVPHRWATLEESVRWIR 150 AL+ + N ++R HFAR+LVECG +VF YL GK GYVP +W T+E+++ I Sbjct: 134 ALR-LANGGAVTRGHFARFLVECGKAATMADVFKKYLARGKTGYVPPQWCTIEQAIDVIH 192 Query: 151 GAGGVAVIAHPGRYKYTQTQFGALFDEFKQLGGEAIEVNTGSHTPEQYQEYAQVARSYGF 210 +GG AV+AHPGRY + L F G+A+EV +P + + A +AR + Sbjct: 193 HSGGKAVLAHPGRYDLSAKWLKRLVAHFADHHGDAMEVAQCQQSPNERTQLATLARQHHL 252 Query: 211 LASMGSDFHGPGESRMDLGGLPPLPTGVKPVWHDW 245 AS+GSDFH P ++LG LP GV+ VW W Sbjct: 253 WASLGSDFHQPC-PWIELGRKLWLPAGVEGVWQTW 286