BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0015.0285.p         (338 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSp1583 [E] COG2873 O-acetylhomoserine sulfhydrylase Rso Ralston...   333   3e-91
TM0882 [E] COG2873 O-acetylhomoserine sulfhydrylase Tma Thermoto...   177   4e-44
mlr8465 Non COG                                                       166   8e-41
PM0738 [E] COG2873 O-acetylhomoserine sulfhydrylase Pmu Pasteure...   162   1e-39
APE1226 [E] COG0626 Cystathionine beta-lyases/cystathionine gamm...   161   2e-39

>RSp1583 [E] COG2873 O-acetylhomoserine sulfhydrylase Rso Ralstonia
           solanacearum
          Length = 423

 Score =  333 bits (854), Expect = 3e-91,   Method: Compositional matrix adjust.
 Identities = 168/279 (60%), Positives = 201/279 (72%), Gaps = 1/279 (0%)

Query: 8   GFTTTILHSDRQKGIEHGSLHKPIHTSVTFGYEDARQLAEVFQGKQPGYRYGRQGNPTVS 67
           G TT +LH+DR+ GIEH ++HKP+HTS T+GY D R L +VFQGK PGY Y RQGNPT +
Sbjct: 15  GLTTALLHADREAGIEHYAVHKPLHTSTTYGYADTRDLIDVFQGK-PGYTYARQGNPTTA 73

Query: 68  ALEDKITKMEDGKSTICFATGMAAIGAIVQGLLREGDHVVSSAFLFGNTNSLWMTVGAQG 127
           ALE KIT MEDG +T CFATGMAAI A+   LLR GDHVVSSAFLFGNTNS++ T+   G
Sbjct: 74  ALEAKITMMEDGLATACFATGMAAIAAVFSTLLRAGDHVVSSAFLFGNTNSVFETLRNLG 133

Query: 128 AKVSMVDATDVKNVEAAITPQTRLVFVETIANPRTQVADLKRIGELCRERGILYVVDNTM 187
            +V+ VDAT  + V  A+ P TRLVFVETIANPRTQVADL  IG LC+ RG+LYV+D+TM
Sbjct: 134 VEVTFVDATSAQAVADAVQPNTRLVFVETIANPRTQVADLGGIGALCKARGLLYVIDSTM 193

Query: 188 TSPYLFRPKTVGAGLVVNSLTKSIGGHGNALGGALTDTGEYDWTRYPHIADSYKKNPAPQ 247
           TSP+LFR +   AGLVV+SL+K IGGHGNALGGA+ DTG +DWT YP+I  +Y+K     
Sbjct: 194 TSPWLFRCRDAQAGLVVHSLSKYIGGHGNALGGAVVDTGLFDWTAYPNIFPAYRKVKPEM 253

Query: 248 WGMAQIRAKARGXLPPRRCATLAPRWARKRHTTSPSVPR 286
            G+ QIR K    L     A  A R A    T +  V R
Sbjct: 254 QGIQQIRKKGLRDLGATLIADAAHRIAIGAETMALRVDR 292


>TM0882 [E] COG2873 O-acetylhomoserine sulfhydrylase Tma Thermotoga
           maritima
          Length = 430

 Score =  177 bits (448), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 97/251 (38%), Positives = 148/251 (58%), Gaps = 11/251 (4%)

Query: 3   DKKTYGFTTTILHSDRQKGIEH-GSLHKPIHTSVTFGYEDARQLAEVFQGKQPGYRYGRQ 61
           D K YG+ T  LH+  +   +  GS   PI+ + ++ + D+   A +F  ++PG+ Y R 
Sbjct: 2   DWKKYGYNTRALHAGYEPPEQATGSRAVPIYQTTSYVFRDSDHAARLFALEEPGFIYTRI 61

Query: 62  GNPTVSALEDKITKMEDGKSTICFATGMAAIGAIVQGLLREGDHVVSSAFLFGNTNSLW- 120
           GNPTVS LE++I  +E+G   +  A+G AAI   +  +   GD +VS + L+G T +L+ 
Sbjct: 62  GNPTVSVLEERIAALEEGVGALAVASGQAAITYAILNIAGPGDEIVSGSALYGGTYNLFR 121

Query: 121 -MTVGAQGAKVSMVDATDVKNVEAAITPQTRLVFVETIANPRTQVADLKRIGELCRERGI 179
                  G  V  VD TD KN+E AIT +T+ V++ETI NP   V D + I E+    G+
Sbjct: 122 HTLYKKSGIIVKFVDETDPKNIEEAITEKTKAVYLETIGNPGLTVPDFEAIAEIAHRHGV 181

Query: 180 LYVVDNTMTSPYLFRPKTVGAGLVVNSLTKSIGGHGNALGGALTDTGEYDWT--RYPHIA 237
             +VDNT+ +PY+FRP   GA +VV S TK IGGHG ++GG + D+G++DWT  ++P + 
Sbjct: 182 PLIVDNTV-APYIFRPFEHGADIVVYSATKFIGGHGTSIGGLIVDSGKFDWTNGKFPELV 240

Query: 238 DSYKKNPAPQW 248
           +     P P +
Sbjct: 241 E-----PDPSY 246


>mlr8465 Non COG
          Length = 426

 Score =  166 bits (420), Expect = 8e-41,   Method: Compositional matrix adjust.
 Identities = 87/249 (34%), Positives = 145/249 (58%), Gaps = 9/249 (3%)

Query: 5   KTYGFTTTILHSDRQKGIEHGSLHKPIHTSVTFGYEDARQLAEVFQGKQPGYRYGRQGNP 64
           +T GF T  +H+  +     G+   PI+ + +F ++DA   A +F  K  G  Y R  NP
Sbjct: 3   RTPGFNTLAVHAGAKPDPATGARATPIYQTTSFVFDDADHAASLFGLKAFGNIYTRIMNP 62

Query: 65  TVSALEDKITKMEDGKSTICFATGMAAIGAIVQGLLREGDHVVSSAFLFGNT-NSLWMTV 123
           T + LE+++  +E G + +  A+G AA   +   L++ GD+ V++  L+G + N      
Sbjct: 63  TQAVLEERVAALEGGTAALAVASGHAAQVIVFHNLMQPGDNFVAATRLYGGSINQFGHAF 122

Query: 124 GAQGAKVSMVDATDVKNVEAAITPQTRLVFVETIANPRTQVADLKRIGELCRERGILYVV 183
              G +V   D  D+   E+ I  +T+ +F+E++ANP     D+++IG++ R+ G+  +V
Sbjct: 123 KNYGWEVRWADTNDLSTFESQIDDRTKAIFIESLANPGGTFVDIEKIGDIARKHGLPLIV 182

Query: 184 DNTMTSPYLFRPKTVGAGLVVNSLTKSIGGHGNALGGALTDTGEYDWT---RYPHIADSY 240
           DNT+ SPYL RP   GA +VV+SLTK IGGHGN++GG + D G +DW+   +YP +++  
Sbjct: 183 DNTLASPYLIRPIEHGADIVVHSLTKFIGGHGNSIGGVIVDGGTFDWSKSGKYPMLSE-- 240

Query: 241 KKNPAPQWG 249
              P P++G
Sbjct: 241 ---PRPEYG 246


>PM0738 [E] COG2873 O-acetylhomoserine sulfhydrylase Pmu Pasteurella
           multocida
          Length = 422

 Score =  162 bits (409), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 80/213 (37%), Positives = 132/213 (61%), Gaps = 4/213 (1%)

Query: 29  KPIHTSVTFGYEDARQLAEVFQGKQPGYRYGRQGNPTVSALEDKITKMEDGKSTICFATG 88
           +PI  S TF Y+ A ++ ++F  +  GY Y R  NPT +A E+KIT +E G +T+C A+G
Sbjct: 22  QPIVQSTTFTYDSAEEIGKLFDLQAAGYFYTRLSNPTTNAAEEKITALEGGVATMCTASG 81

Query: 89  MAAIGAIVQGLLREGDHVVSSAFLFGNTNSLWM-TVGAQGAKVSMVDA-TDVKNVEAAIT 146
            AA+   +  +L+ GDH +SS++++G + +L+  T    G +V+ VD    ++ ++ AI 
Sbjct: 82  QAAVFYAMLNILQAGDHFISSSYVYGGSYNLFAHTFKKMGIEVTFVDQDLPLEELKKAIR 141

Query: 147 PQTRLVFVETIANPRTQVADLKRIGELCRERGILYVVDNTMTSPYLFRPKTVGAGLVVNS 206
           P T+ +F ETIANP  +V D+++   L +      +VDNT  +PY  RP   GA +V++S
Sbjct: 142 PNTKAIFAETIANPALRVLDIEKFVALAKAAQAPLLVDNTFATPYFCRPIEFGANVVIHS 201

Query: 207 LTKSIGGHGNALGGALTDTGEYDWT--RYPHIA 237
            +K + GH  ALGG++TD G +DW   ++P ++
Sbjct: 202 TSKYLDGHAIALGGSITDGGNFDWNNGKFPQLS 234


>APE1226 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
           Ape Aeropyrum pernix
          Length = 384

 Score =  161 bits (407), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 91/230 (39%), Positives = 137/230 (59%), Gaps = 11/230 (4%)

Query: 8   GFTTTILHS-DRQKGIEHGSLHKPIHTSVTFGYEDARQLAEVFQGKQPGYRYGRQGNPTV 66
           GFTT  +H+ +  +   HG +  PIH SVT+     R +AE     + GY Y R  NPT 
Sbjct: 3   GFTTKAVHAGEDPRETLHGDVVHPIHLSVTYW---KRSVAEA----EEGYVYSRTSNPTR 55

Query: 67  SALEDKITKMEDGKSTICFATGMAAIGAIVQGLLREGDHVVSSAFLFGNTNSLWMTVGAQ 126
            ALE K+  +E+ +  + F++G+AA   ++  LLREGDH+V+   L+G T  L+  V A+
Sbjct: 56  DALEKKLAALENARYALAFSSGLAAEATVILALLREGDHIVAFDDLYGGTKRLFQRVMAR 115

Query: 127 -GAKVSMVDATDVKNVEAAITPQTRLVFVETIANPRTQVADLKRIGELCRERGILYVVDN 185
            G KV+ VDA D  N+E A+TP TR++++ET  NP  ++ D++   E+    G   VVDN
Sbjct: 116 FGIKVTYVDARDPGNIEKALTPATRMIWLETPTNPLLKLTDIRAAAEIASRAGAYLVVDN 175

Query: 186 TMTSPYLFRPKTVGAGLVVNSLTKSIGGHGNALGGA-LTDTGE-YDWTRY 233
           T  +PY  RP  +GA +VV+S TK + GH + L GA + ++ E Y+  +Y
Sbjct: 176 TFATPYFQRPLELGADIVVHSATKYLSGHSDLLAGAVMVNSSEVYEKLKY 225