BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0264.p (629 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1564_1 [GEPR] COG0477 Permeases of the major facilitator supe... 475 e-133 PA3267_1 [GEPR] COG0477 Permeases of the major facilitator super... 363 e-100 VC1966_1 [GEPR] COG0477 Permeases of the major facilitator super... 353 7e-97 NMB1515 [GEPR] COG0477 Permeases of the major facilitator superf... 295 2e-79 NMA1715 [GEPR] COG0477 Permeases of the major facilitator superf... 295 3e-79 >RSc1564_1 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 434 Score = 475 bits (1222), Expect = e-133, Method: Compositional matrix adjust. Identities = 246/435 (56%), Positives = 305/435 (70%), Gaps = 8/435 (1%) Query: 1 MQKNSQFTLFSQRRFAPFFWTQFLGALNDNVFKTALLTILTYDALSWTDMDPGLLNNLIP 60 M ++SQF+L QRRFAPFFWTQFLGA+NDNVFK A +++TY A + + DP LI Sbjct: 1 MSQSSQFSLLKQRRFAPFFWTQFLGAMNDNVFKVAFSSLVTYHAALFGNADPASAAFLIS 60 Query: 61 GLFILPFFLFSATSGQLSDKLEKGRVARFVKLLEIAIMCVAAYGWMTHHLWLLIAAVIGM 120 +FI PF L SATSGQ++D+++K R+ R VK LEIAIM + G+ + LL M Sbjct: 61 AIFIAPFVLLSATSGQIADRMDKARLIRLVKTLEIAIMAIGCAGFALRRVELLYLCTFLM 120 Query: 121 GVHSTLFGPVKYAYLPQQLKREELVGGNGLIEMGTFVGILLGEILGAVLVVHKPWGLHLV 180 GVHSTLFGPVKYAYLPQ L+ ELVGGNGL+EMGTFV ILLG I G L G LV Sbjct: 121 GVHSTLFGPVKYAYLPQHLQPSELVGGNGLVEMGTFVAILLGTIGGGELANLTRNG-ELV 179 Query: 181 AGITIGIAVL-----GWLASLRIPLSPAPVPDLKVNWNPFTETVRNLGYSRRNRPVFLSL 235 GIA L GWL + +P+SPA PDL++NWNP +ET RNL + R VFLSL Sbjct: 180 GPALTGIACLAIAVGGWLTARGVPVSPASQPDLRINWNPVSETWRNLKLASNQRAVFLSL 239 Query: 236 LGNSWFWFYGAIMLAQFPVYAKNYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEI 295 LG SW WF GA L F +A+N L GD +V LLLAVFS+GIG GS+LCE+LSG VE+ Sbjct: 240 LGISWLWFVGATFLTSFFAFARNVLGGDQNVVTLLLAVFSIGIGLGSVLCEKLSGRMVEV 299 Query: 296 GLVPFGSIGLSVFGLELYFAS--QAYVTPSAMLDLGGFLAQGGSWRILFDCLGIGLFGGL 353 GLVPFGSIG++VF ++LYFAS +A V A+ + GFL WR+L D + +FGG Sbjct: 300 GLVPFGSIGMTVFAVDLYFASHAEALVAHDALTGVAGFLQNHRHWRVLADLFLLAMFGGF 359 Query: 354 YIVPLFALIQTRCDPAHVSRTIAGMNIMNALFMVVSAVVAMVLLKAGLTIPQIFLATAIM 413 Y VPL+ALIQ+RC+P H +R IA NI+NALFM+ SAV+AMVL +AG TIPQ+FL T I+ Sbjct: 360 YSVPLYALIQSRCEPTHRARIIAANNILNALFMIASAVLAMVLTRAGFTIPQLFLVTGIL 419 Query: 414 NGVVAVYIFSLVPEF 428 N VVA+YI++L+PEF Sbjct: 420 NAVVAIYIYTLLPEF 434 >PA3267_1 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 428 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 221/430 (51%), Positives = 282/430 (65%), Gaps = 5/430 (1%) Query: 1 MQKNSQFTLFSQRRFAPFFWTQFLGALNDNVFKTALLTILTYDALSWTDMDPGLLNNLIP 60 M ++SQF L +RRF PFF TQ LGA NDN+FK +L+ + Y LS + D LL NL Sbjct: 1 MTQHSQFALLGKRRFLPFFITQLLGAFNDNIFKQSLILAILYH-LSVSG-DRSLLVNLCA 58 Query: 61 GLFILPFFLFSATSGQLSDKLEKGRVARFVKLLEIAIMCVAAYGWMTHHLWLLIAAVIGM 120 LFILPFFLFSA GQ +K K + R +KL E+ IM V A G++ L L+ A+ M Sbjct: 59 LLFILPFFLFSALGGQFGEKYNKDALMRALKLAEVGIMLVGAAGFVFGSLPLMFVALFAM 118 Query: 121 GVHSTLFGPVKYAYLPQQLKREELVGGNGLIEMGTFVGILLGEILGAVLVVHKPWGLHLV 180 G HS LFGPVKY+ LPQ L +ELVGGN L+EMGTF+ IL G I VL+ H + + Sbjct: 119 GTHSALFGPVKYSILPQHLHEDELVGGNALVEMGTFLAILAGTIGAGVLMSHAHYAAAVA 178 Query: 181 AGITIGIAVLGWLASLRIPLSPAPVPDLKVNWNPFTETVRNLGYSRRNRP-VFLSLLGNS 239 + + +A G+LAS IP + A +P LK++WN F ++ L RP V SL+GNS Sbjct: 179 TAVVL-VAACGYLASRGIPRAAAALPGLKLDWNIFAQSWSILRLGLGQRPAVSRSLVGNS 237 Query: 240 WFWFYGAIMLAQFPVYAKNYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEIGLVP 299 WFWF GA+ L Q P +AK +LHGD SV L+L VFSVGI GS+LCE+LSG KVEIGLVP Sbjct: 238 WFWFLGAVYLTQIPTFAKEWLHGDESVVTLILTVFSVGIALGSMLCEKLSGRKVEIGLVP 297 Query: 300 FGSIGLSVFGLELYFASQAYVTPSAMLDLGGFLAQGGSWRILFDCLGIGLFGGLYIVPLF 359 FGSIGL+VFG+ L++ + A D L +W +L D L IG+FGG YIVPL+ Sbjct: 298 FGSIGLTVFGILLWWHAGGIPPGEAPYDWLAVLRHHETWAVLADILFIGIFGGFYIVPLY 357 Query: 360 ALIQTRCDPAHVSRTIAGMNIMNALFMVVSAVVAMVLLK-AGLTIPQIFLATAIMNGVVA 418 ALIQ R D +R IA NI+NALFMV +A+V+++ L A L+IPQ+FLA ++MN V Sbjct: 358 ALIQARTDEDKRARVIAANNILNALFMVAAALVSILFLSVAKLSIPQLFLALSLMNVAVN 417 Query: 419 VYIFSLVPEF 428 VYIF +VPEF Sbjct: 418 VYIFKIVPEF 427 >VC1966_1 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 429 Score = 353 bits (906), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 198/426 (46%), Positives = 267/426 (62%), Gaps = 4/426 (0%) Query: 4 NSQFTLFSQRRFAPFFWTQFLGALNDNVFKTALLTILTYDALSWTDMDPGLLNNLIPGLF 63 N L ++RRF P+F TQFLGA NDN+FK LL + + + L NL GLF Sbjct: 6 NPTTALLTERRFLPYFITQFLGAFNDNIFKNVLLLFVAFAGPQALPISSNLFINLAAGLF 65 Query: 64 ILPFFLFSATSGQLSDKLEKGRVARFVKLLEIAIMCVAAYGWMTHHLWLLIAAVIGMGVH 123 ILPFFLFSAT+G L+DKLEK R R+VKLLEIAIM A G++T + + + MG Sbjct: 66 ILPFFLFSATAGVLADKLEKSRYIRWVKLLEIAIMLCGAIGFITQSYGISLFLLFLMGTQ 125 Query: 124 STLFGPVKYAYLPQQLKREELVGGNGLIEMGTFVGILLGEILGAVLVVHKPWGLHLVAGI 183 S FGPVKYA LPQQLK EELV GN L+E GTF+ ILLG LGA L+ + A Sbjct: 126 SAFFGPVKYALLPQQLKSEELVPGNALVETGTFLAILLGT-LGAGLIASADNAHYFAAAA 184 Query: 184 TIGIAVLGWLASLRIPLSPAPVPDLKVNWNPFTETVRNLGYSRRNRPVFLSLLGNSWFWF 243 + AVLG+L+S IPL+PA P L+ W P T+T + L ++R+R +F S++ SWFWF Sbjct: 185 VVIFAVLGYLSSRAIPLAPASAPHLEFRWQPITQTKQTLRIAKRDRAIFQSIMAISWFWF 244 Query: 244 YGAIMLAQFPVYAKNYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEIGLVPFGSI 303 GA L QFP + K +L+G+ + LLA+FSVGI GSL C++LSGH++E+G+VP GS+ Sbjct: 245 LGAGYLTQFPNFTKLHLNGNEAAVSFLLALFSVGIAVGSLACDKLSGHRIEVGIVPLGSV 304 Query: 304 GLSVFGLELYFASQAYVTPSAMLDLGGFLAQGGSWRILFDCLGIGLFGGLYIVPLFALIQ 363 G+S FG + A+ F+ W + L IG+FGG++IVPL+A++Q Sbjct: 305 GISFFGYLM--ATSIPADLPIFSTFADFVTYSALWPLFAYLLLIGVFGGVFIVPLYAMLQ 362 Query: 364 TRCDPAHVSRTIAGMNIMNALFMVVSAVVAMVLLKA-GLTIPQIFLATAIMNGVVAVYIF 422 R ++ IA +NI N+LFMV SA + +V L ++IPQ+F A++N +VA+YIF Sbjct: 363 QRAKVTERAQVIAALNIYNSLFMVGSAALGIVCLSVLEMSIPQLFALLAVLNVLVALYIF 422 Query: 423 SLVPEF 428 VP F Sbjct: 423 LQVPIF 428 >NMB1515 [GEPR] COG0477 Permeases of the major facilitator superfamily Nme Neisseria meningitidis MC58 Length = 436 Score = 295 bits (756), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 178/428 (41%), Positives = 258/428 (60%), Gaps = 5/428 (1%) Query: 3 KNSQFTLFSQRRFAPFFWTQFLGALNDNVFKTALLTILTYDALSWTDMDP-GLLNNLIPG 61 K L RRFAP F TQFLGA NDNVFKTAL ++ + L P G + NL Sbjct: 4 KKGGLGLVKSRRFAPLFATQFLGAFNDNVFKTALFVMIGFYGLGQNGFLPAGQMLNLGAL 63 Query: 62 LFILPFFLFSATSGQLSDKLEKGRVARFVKLLEIAIMCVAAYGWMTHHLWLLIAAVIGMG 121 LFILP+FLFS+ SGQL +K +K +AR+VK+LE+ IM VAAYG+ LL+A + MG Sbjct: 64 LFILPYFLFSSLSGQLGNKFDKAVLARWVKVLEMIIMAVAAYGFYIRSAPLLLACLFCMG 123 Query: 122 VHSTLFGPVKYAYLPQQLKREELVGGNGLIEMGTFVGILLGEILGAVLVVHKPWGLHLVA 181 STLFGP+KYA LP L +EL+ GN LIE GTFV IL G+ILG + P ++V Sbjct: 124 AQSTLFGPLKYAILPDYLDDKELMMGNSLIESGTFVAILFGQILGTAVAGVPP---YIVG 180 Query: 182 GITIGIAVLGWLASLRIPLSPAPVPDLKVNWNPFTETVRNLGYSRRNRPVFLSLLGNSWF 241 + + +AV G + SL +P PA D ++ WN T L + R++PVF +++G SWF Sbjct: 181 ILVLLVAVGGTVGSLFMPSVPAKAADTQIEWNIVRGTKSLLRETVRHKPVFTAIIGISWF 240 Query: 242 WFYGAIMLAQFPVYAKNYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEIGLVPFG 301 WF GA+ Q P + + +L G+ +VF L+LA+FS+GI AGS+LC + S ++ + V G Sbjct: 241 WFVGAVYTTQLPTFTQIHLGGNDNVFNLMLALFSIGIAAGSVLCAKFSRERLMLAWVTVG 300 Query: 302 SIGLSVFGLELYFASQAYVTPSAMLDLGGFLAQGGSWRILFDCLGIGLFGGLYIVPLFAL 361 ++GL+V GL L + + + + + FL+QG ++ ++ IG FGG + VPL+ Sbjct: 301 ALGLTVCGLVLVWLTHGH-RFEGLNGIFWFLSQGWAYPVMAVMTLIGFFGGFFSVPLYTW 359 Query: 362 IQTRCDPAHVSRTIAGMNIMNALFMVVSAVVAMVLLKAGLTIPQIFLATAIMNGVVAVYI 421 +QT +R +A NI+N +FMV +AV++ VLL +I ++L A+ N ++V++ Sbjct: 360 LQTASSETFRARAVAANNIVNGIFMVSAAVLSAVLLFLFDSISLLYLIVALGNIPLSVFL 419 Query: 422 FSLVPEFL 429 FL Sbjct: 420 IKRERRFL 427 >NMA1715 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 436 Score = 295 bits (754), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 177/428 (41%), Positives = 257/428 (60%), Gaps = 5/428 (1%) Query: 3 KNSQFTLFSQRRFAPFFWTQFLGALNDNVFKTALLTILTYDALSWTDMDP-GLLNNLIPG 61 K L RRFAP F TQFLGA NDNVFKTAL ++ + L P G + NL Sbjct: 4 KKGGLGLVKSRRFAPLFATQFLGAFNDNVFKTALFVMIGFYGLGQNGFLPAGQMLNLGAL 63 Query: 62 LFILPFFLFSATSGQLSDKLEKGRVARFVKLLEIAIMCVAAYGWMTHHLWLLIAAVIGMG 121 LFILP+FLFS+ SGQL +K +K +AR+ K+LE+ IM VAAYG+ LL+A + MG Sbjct: 64 LFILPYFLFSSLSGQLGNKFDKAVLARWAKVLEMIIMAVAAYGFYIRSAPLLLACLFCMG 123 Query: 122 VHSTLFGPVKYAYLPQQLKREELVGGNGLIEMGTFVGILLGEILGAVLVVHKPWGLHLVA 181 STLFGP+KYA LP L +EL+ GN LIE GTFV IL G+ILG + P ++V Sbjct: 124 AQSTLFGPLKYAILPDYLDDKELMMGNSLIESGTFVAILFGQILGTAVAGVPP---YIVG 180 Query: 182 GITIGIAVLGWLASLRIPLSPAPVPDLKVNWNPFTETVRNLGYSRRNRPVFLSLLGNSWF 241 + + +AV G + SL +P PA D ++ WN T L + R++PVF +++G SWF Sbjct: 181 ILVLLVAVGGTVGSLFMPSVPAKAADTQIEWNIVRGTKSLLRETVRHKPVFTAIIGISWF 240 Query: 242 WFYGAIMLAQFPVYAKNYLHGDHSVFVLLLAVFSVGIGAGSLLCERLSGHKVEIGLVPFG 301 WF GA+ Q P + + +L G+ +VF L+LA+FS+GI AGS+LC + S ++ + V G Sbjct: 241 WFVGAVYTTQLPTFTQIHLGGNDNVFNLMLALFSIGIAAGSVLCAKFSRERLRLAWVTVG 300 Query: 302 SIGLSVFGLELYFASQAYVTPSAMLDLGGFLAQGGSWRILFDCLGIGLFGGLYIVPLFAL 361 ++GL+V GL L + + + + + FL+QG ++ ++ IG FGG + VPL+ Sbjct: 301 ALGLTVCGLVLVWLTHGH-RFEGLNGIFWFLSQGWAYPVMAVMTLIGFFGGFFSVPLYTW 359 Query: 362 IQTRCDPAHVSRTIAGMNIMNALFMVVSAVVAMVLLKAGLTIPQIFLATAIMNGVVAVYI 421 +QT +R +A NI+N +FMV +AV++ VLL +I ++L A+ N ++V++ Sbjct: 360 LQTASSETFRARAVAANNIVNGIFMVSAAVLSAVLLFLFDSISLLYLIVALGNIPLSVFL 419 Query: 422 FSLVPEFL 429 FL Sbjct: 420 IKRERRFL 427