BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0015.0251.p         (199 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA2025 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex...   176   4e-44
BMEI0972 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase compl...   141   9e-34
CC2302 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex...   139   4e-33
all4968 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase comple...   136   3e-32
mll0523 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase comple...   135   4e-32

>PA2025 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex,
           dihydrolipoamide dehydrogenase (E3) component, and
           related enzymes Pae Pseudomonas aeruginosa
          Length = 451

 Score =  176 bits (445), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 85/148 (57%), Positives = 108/148 (72%), Gaps = 1/148 (0%)

Query: 1   MSYSAHFHEDFADAAGYGWTLHSEPTFDWSALIANKDREITHLNGIYQRLLDGANVSLHR 60
           + Y AHF EDF  A  YGW+   E  FDW+ LI NK+REI  LNGIY+ LL  + V+L  
Sbjct: 53  LVYGAHFSEDFEQARAYGWS-AGEAQFDWATLIGNKNREIQRLNGIYRNLLVNSGVTLLE 111

Query: 61  GFATVEDAHTVSVEGKRFTARHILVATGGHPDKPQIPGSELGITSDDFFHLKSLPKRAVV 120
           G A + DAH+V V+G+RF+A+HILVATGG P  P IPG E  ITS++ F L+ LP+R +V
Sbjct: 112 GHARLLDAHSVEVDGQRFSAKHILVATGGWPQVPDIPGKEHAITSNEAFFLERLPRRVLV 171

Query: 121 LGGGYIAVELASILNGLGSDVTLVYRRE 148
           +GGGYIAVE ASI NGLG++ TL+YRR+
Sbjct: 172 VGGGYIAVEFASIFNGLGAETTLLYRRD 199


>BMEI0972 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex,
           dihydrolipoamide dehydrogenase (E3) component, and
           related enzymes Bme Brucella melitensis
          Length = 483

 Score =  141 bits (356), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 71/147 (48%), Positives = 102/147 (69%), Gaps = 4/147 (2%)

Query: 3   YSAHFHEDFADAAGYGWTLHSEPTFDWSALIANKDREITHLNGIYQRLLDGANVSLHRGF 62
           Y++ F E F D+AGYGW++  E  FDW  LIA KD+EI+ L G+Y++ L+ ++V +    
Sbjct: 75  YASQFPEHFEDSAGYGWSM-GEAAFDWKKLIAAKDKEISRLEGLYRKGLENSHVDIFASR 133

Query: 63  ATVEDAHTVSV--EGKRFTARHILVATGGHPDKPQ-IPGSELGITSDDFFHLKSLPKRAV 119
           A + D HT+ +  +G+R TA  IL+ATGG P+  + +PG E  I+S++ FHL+ LPK  V
Sbjct: 134 AELIDEHTIELKADGRRVTADKILIATGGRPNTHESLPGHEYCISSNEAFHLEELPKSIV 193

Query: 120 VLGGGYIAVELASILNGLGSDVTLVYR 146
           + GGGYIAVE A+I +GLG + TLVYR
Sbjct: 194 IAGGGYIAVEFANIFHGLGVETTLVYR 220


>CC2302 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex,
           dihydrolipoamide dehydrogenase (E3) component, and
           related enzymes Ccr Caulobacter vibrioides
          Length = 466

 Score =  139 bits (350), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 76/153 (49%), Positives = 91/153 (59%), Gaps = 8/153 (5%)

Query: 1   MSYSAHFHEDFADAAGYGWTLHSEPTFDWSALIANKDREITHLNGIYQRLLDGANVSLHR 60
           M Y++        A GYGWT+  +  FDW   +  KD EI  L+GIY   L  A   L  
Sbjct: 54  MVYASEVTSQLKTAKGYGWTIE-DARFDWKTFLHEKDVEIARLSGIYVTNLQKAGAHLLH 112

Query: 61  GFATVEDAHTVSVEGK-------RFTARHILVATGGHPDKPQIPGSELGITSDDFFHLKS 113
           G A + DAHTV V  K        +TAR ILVATGG P +P  PG+ELGITSD+ FHL +
Sbjct: 113 GRAQIVDAHTVEVLPKDGSDDAGTYTARKILVATGGRPVRPVFPGAELGITSDEAFHLPT 172

Query: 114 LPKRAVVLGGGYIAVELASILNGLGSDVTLVYR 146
           LPK  +V+GGGYIAVE A I  GLG   TL+YR
Sbjct: 173 LPKSVLVVGGGYIAVEFAGIYAGLGVQTTLLYR 205


>all4968 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex,
           dihydrolipoamide dehydrogenase (E3) component, and
           related enzymes Nos Nostoc sp. PCC 7120
          Length = 459

 Score =  136 bits (342), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 67/146 (45%), Positives = 91/146 (62%), Gaps = 1/146 (0%)

Query: 1   MSYSAHFHEDFADAAGYGWTLHSEPTFDWSALIANKDREITHLNGIYQRLLDGANVSLHR 60
           M Y +HF   F DAAGYGW +  +   +W   I + D+E+  L+ ++   L+ A V L  
Sbjct: 53  MVYGSHFPALFEDAAGYGWQV-GKAELNWEHFITSIDKEVRRLSQLHISFLEKAGVELIS 111

Query: 61  GFATVEDAHTVSVEGKRFTARHILVATGGHPDKPQIPGSELGITSDDFFHLKSLPKRAVV 120
           G AT+ D HTV V  ++FTA  IL+A GG P KP++PG E GITS++ FHLK+ PK   +
Sbjct: 112 GRATLVDNHTVEVGERKFTADKILIAVGGRPIKPELPGMEYGITSNEIFHLKTQPKHIAI 171

Query: 121 LGGGYIAVELASILNGLGSDVTLVYR 146
           +G GYI  E A I+ GLGS VT + R
Sbjct: 172 IGSGYIGTEFAGIMRGLGSQVTQITR 197


>mll0523 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex,
           dihydrolipoamide dehydrogenase (E3) component, and
           related enzymes Mlo Mesorhizobium loti
          Length = 463

 Score =  135 bits (341), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 73/147 (49%), Positives = 96/147 (65%), Gaps = 4/147 (2%)

Query: 3   YSAHFHEDFADAAGYGWTLHSEPTFDWSALIANKDREITHLNGIYQRLLDGANVSLHRGF 62
           Y++ F E FADAAGYGWT+  E +F+W  L+ANKDREI+ L  IY++ ++GA        
Sbjct: 56  YASQFPEHFADAAGYGWTV-PEASFNWQTLVANKDREISRLEAIYKKNVEGAGGETFPSR 114

Query: 63  ATVEDAHTVSV--EGKRFTARHILVATGGHPDK-PQIPGSELGITSDDFFHLKSLPKRAV 119
           A + D H V +  + +  TA  IL+ATGG P   P +PG E  I S++ F LK LPK  +
Sbjct: 115 AMIVDPHVVHLLDDDRTVTADQILIATGGRPAAHPALPGHEHCIFSNEAFDLKELPKAIM 174

Query: 120 VLGGGYIAVELASILNGLGSDVTLVYR 146
           + GGGYIAVE A+I +GLG D TLVYR
Sbjct: 175 IEGGGYIAVEFANIFHGLGVDTTLVYR 201