BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0228.p (414 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1932 [GEPR] COG0477 Permeases of the major facilitator superf... 452 e-127 PA2114 [GEPR] COG0477 Permeases of the major facilitator superfa... 427 e-119 RSp0234 [GEPR] COG0477 Permeases of the major facilitator superf... 393 e-109 PM0835 [GEPR] COG0477 Permeases of the major facilitator superfa... 223 6e-58 RSp0797 [GEPR] COG0477 Permeases of the major facilitator superf... 198 2e-50 >YPO1932 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 409 Score = 452 bits (1163), Expect = e-127, Method: Compositional matrix adjust. Identities = 225/407 (55%), Positives = 295/407 (72%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W + +ER+T A F G+A+D D+M++TF+I TL+A W + +AG ++T LL SA Sbjct: 3 WFSDLNQTERKTFIAAFGGWALDALDFMVFTFVIATLMALWQIDAGQAGMLSTVTLLFSA 62 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFALFTFLSGFTTSFGELFFTRAMQGFGMGGEWAVG 121 IGGW AG+LADRYGRVR+LQ T+LWF+L T L GF +F +F RA+QG G GGEWAVG Sbjct: 63 IGGWGAGILADRYGRVRILQITILWFSLCTVLIGFAQNFEHVFILRALQGLGFGGEWAVG 122 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAASALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 SVL+ E + A HRGKA G VQS WA+GW A+AL + +++VL E AW+ LFWIGVLPAL Sbjct: 123 SVLMGEIVRAEHRGKAVGTVQSGWAIGWGAAALLYTLMFSVLSEEWAWRALFWIGVLPAL 182 Query: 182 LTLYIRRAISEPEVFLATQARLRESGQRGNFLRIFHRDLLRTTLLASLLATGMQGAYYSV 241 L LYIR+ + EP +FL ++ + +R + IF LL+TT+LASLL TG+QG YY++ Sbjct: 183 LVLYIRKNVPEPALFLKSRHEQQAKDRRVSSFAIFSPALLKTTVLASLLCTGVQGGYYAI 242 Query: 242 TTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVL 301 TTWLPTFLK ER+LSV+GT YL+V+I GSF GY+ A+L+D +GRR ++F+ + + Sbjct: 243 TTWLPTFLKLERNLSVIGTGGYLMVIIFGSFVGYICGAYLTDKLGRRANLIIFSLLSCIT 302 Query: 302 VLSYTQLIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVG 361 + +YTQL +T+ ML LGF LGF SGIFSGMGA+L+ELFPS VR +GQGF Y+FGRAVG Sbjct: 303 IFAYTQLTLTNTQMLVLGFPLGFSASGIFSGMGAFLTELFPSAVRATGQGFTYSFGRAVG 362 Query: 362 AICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLILPETRGKELE 408 A+ P LVGYLS S L IG A Y +V+V L+LPET+ K+LE Sbjct: 363 ALFPGLVGYLSQSSSLAFAIGVFAGSAYCIVLVMSLLLPETKNKQLE 409 >PA2114 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 423 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 221/408 (54%), Positives = 283/408 (69%), Gaps = 3/408 (0%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W + ERR + GY +DG D + +F+IPTL+A W + EAG+I T LL SA Sbjct: 17 WYRALDKQERRAFWSCKIGYGLDGMDTQMLSFVIPTLIALWGIGTGEAGFIHTMTLLASA 76 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFALFTFLSGFTTSFGELFFTRAMQGFGMGGEWAVG 121 GGW AG+L+DR GRV LQ TVLWFA FTFL G ++ +L R + GFG GGEW G Sbjct: 77 AGGWIAGILSDRIGRVLTLQLTVLWFAFFTFLCGLAQNYEQLLVARTLMGFGFGGEWTAG 136 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAASALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 +VLI E I AR RGKA GLVQS WA+GW +A+ + ++++LPPE AW+ LF +G+LPAL Sbjct: 137 AVLIGEVIKARDRGKAVGLVQSGWAIGWGLTAILYSLMFSLLPPEEAWRALFMLGLLPAL 196 Query: 182 LTLYIRRAISEPEVFLATQARLRESG-QRGNFLRIFHRDLLRTTLLASLLATGMQGAYYS 240 L +RR + EPE++ +AR R G + +F IF +L TL ASLL TG G YY+ Sbjct: 197 FVLVVRRLVKEPEIY--REARQRNQGADKVSFYEIFAPGMLSITLRASLLTTGALGGYYA 254 Query: 241 VTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIV 300 +T WLPTFLKTER L+VLGTS YL ++I GS+ GY+ SA+L+D IGR++ F+LFA Sbjct: 255 ITAWLPTFLKTERGLTVLGTSGYLAMVILGSYVGYVVSAFLTDLIGRKKNFVLFAVGSFT 314 Query: 301 LVLSYTQLIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAV 360 +VL YTQL +++ ML LGF LGFF SGIFSGMG++L+ELFP+ +RGSGQGFCYN GRA+ Sbjct: 315 VVLLYTQLPVSNGAMLWLGFPLGFFASGIFSGMGSFLTELFPTRIRGSGQGFCYNAGRAI 374 Query: 361 GAICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLILPETRGKELE 408 A+ P L+G L L LG IG AA YG+VI+A L LPETRGK+LE Sbjct: 375 AALFPMLIGMLGQKLSLGLGIGAFAAVSYGVVILAALSLPETRGKQLE 422 >RSp0234 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 416 Score = 393 bits (1009), Expect = e-109, Method: Compositional matrix adjust. Identities = 213/417 (51%), Positives = 276/417 (66%), Gaps = 10/417 (2%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W +E + E+RT A F G+A+D D +++ +IPT++AAW + K EAG ++ L+ SA Sbjct: 4 WFKEISAGEKRTFWACFGGWALDALDVQMFSLVIPTIIAAWHIGKTEAGLVSGITLVASA 63 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFALFTFLSGFTTSFGELFFTRAMQGFGMGGEWAVG 121 +GGW AG + DR GRVR LQ TV WF+L TF S F +F + +A+QGFG GGEWA G Sbjct: 64 LGGWIAGAMTDRLGRVRTLQITVAWFSLATFASAFAQNFEQFLALKAVQGFGFGGEWAAG 123 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAASALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 +VL+AE+I A HRGKA G VQS+WAVGW A+ L + Y+++ P+ AW+V+F GVLPAL Sbjct: 124 AVLMAESIRASHRGKAMGTVQSAWAVGWGAAVLLYALTYSLVEPDLAWRVMFAAGVLPAL 183 Query: 182 LTLYIRRAISEPEVFLATQARLRESGQRG------NFLRIFHRDLLRTTLLASLLATGMQ 235 L +YIRR + EP A E+G G L IF +LR TL+ +LL G Sbjct: 184 LIIYIRRGVQEP----APAGAKAEAGPDGMPVSRFPLLDIFRPRVLRMTLIGALLGVGAH 239 Query: 236 GAYYSVTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFA 295 G YY++ TWLPT+LKTERHLSVLGT YL V+I +CG + SAWL D IGRR +LF+ Sbjct: 240 GGYYALMTWLPTYLKTERHLSVLGTGGYLAVIIFAFWCGCVASAWLLDVIGRRGNILLFS 299 Query: 296 AMGIVLVLSYTQLIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYN 355 +V VL Y + ++D ML LGF LGFF +GI + MGA +EL+P VRG+G GFCYN Sbjct: 300 CCCVVTVLVYLLVPLSDGAMLVLGFPLGFFAAGIPASMGALFNELYPHGVRGTGVGFCYN 359 Query: 356 FGRAVGAICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLILPETRGKELEAVVA 412 FGR V A P LVG +S S+ LG IG AA Y +V VA L+LPETRG++L AV A Sbjct: 360 FGRVVSAAFPVLVGKMSASMSLGTAIGIDAAIAYSIVAVAVLMLPETRGRDLAAVTA 416 >PM0835 [GEPR] COG0477 Permeases of the major facilitator superfamily Pmu Pasteurella multocida Length = 405 Score = 223 bits (568), Expect = 6e-58, Method: Compositional matrix adjust. Identities = 135/400 (33%), Positives = 216/400 (54%), Gaps = 8/400 (2%) Query: 12 RTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGGWAAGVLA 71 + L + GYA+DGFD +I F++ + A +++ A++G + T L+ + GG G L+ Sbjct: 11 KALLGSAVGYAMDGFDLLILGFMLSAISADLALTPAQSGSLVTWTLIGAVAGGIIFGALS 70 Query: 72 DRYGRVRVLQWTVLWFALFTFLSGFTTSFGELFFTRAMQGFGMGGEWAVGSVLIAETISA 131 D+YGRVRVL WT++ FA+FT L F + +L R + G G+GGE+ +G L AE A Sbjct: 71 DKYGRVRVLTWTIVLFAVFTGLCAFAQGYWDLLIYRTIAGIGLGGEFGIGMALAAEAWPA 130 Query: 132 RHRGKASGLVQSSWAVGWAASALAFWGVYAVLPPETAWKVLFWIGVLPALLTLYIRRAIS 191 RHR KAS V A+GW L + +L P W+ +F +G+ PA + Y+R + Sbjct: 131 RHRAKASSYV----ALGWQVGVLGAALLTPLLLPHIGWRGMFLVGIFPAFVAWYLRAKLH 186 Query: 192 EPEVFLATQARL-RESGQRGNFLRIFHRDLLRTTLLASLLA-TGMQG-AYYSVTTWLPTF 248 EPE+F+ Q L R+ R R+ +D + A ++ T +Q YY + W+P F Sbjct: 187 EPEIFVKKQTALERQKTSRLEPFRLLIKDKATAKISAGIVVLTSVQNFGYYGIMIWMPNF 246 Query: 249 LKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVLSYTQL 308 L + S+ + + V I G G L+D IGR+ F+LF ++ + +Y+Q+ Sbjct: 247 LSKQLGFSLTKSGVWTAVTICGMMFGIWLFGQLADRIGRKPSFLLFQFGAVISIFTYSQM 306 Query: 309 IITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAICPALV 368 +ML G VLG F++G+ G GA +SE +P+ R + Q +N GRAVG P +V Sbjct: 307 -SDPTYMLFAGAVLGMFVNGMMGGYGALMSEAYPTQARATAQNVLFNLGRAVGGFGPIVV 365 Query: 369 GYLSNSLPLGQTIGWIAAGCYGLVIVACLILPETRGKELE 408 G L ++ I ++A+ +I ++PE +GK+L+ Sbjct: 366 GALVSTYSFQLAIAFLASIYIIDMIATIFLIPELKGKQLD 405 >RSp0797 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 418 Score = 198 bits (504), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 143/406 (35%), Positives = 218/406 (53%), Gaps = 12/406 (2%) Query: 5 ETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGG 64 T+ + L + GYA+DGFD +I F++P + AA +++ E+G + T L+ + GG Sbjct: 21 RTSGDAWKALAGSAIGYAMDGFDLLILGFMLPAISAALALTPGESGALVTWTLVGAVAGG 80 Query: 65 WAAGVLADRYGRVRVLQWTVLWFALFTFLSGFTTSFGELFFTRAMQGFGMGGEWAVGSVL 124 G L+D YGRVRVL WT++ FA+FT + F F +L R + G G+GGE+ +G L Sbjct: 81 ILFGALSDAYGRVRVLTWTIVLFAVFTGMCAFAQGFTDLLIYRTIAGIGLGGEFGIGMAL 140 Query: 125 IAETISARHRGKASGLVQSSWAVGWAASALAFWGVYAVLPPETAWKVLFWIGVLPALLTL 184 AE A R + S V A+GW L + +L P W+ +F +GVLPA + Sbjct: 141 AAEAWPAHKRARVSSYV----ALGWQCGVLLAALLTPLLLPFIGWRGMFLLGVLPAAVAW 196 Query: 185 YIRRAISEPEVFL--ATQARLRESGQRGNFLRIFHRDLLRTTLLASLLATGMQGAYYSVT 242 +IR + EPE+F+ A R + S R L + LRT+L +L YY + Sbjct: 197 FIRNRLHEPELFVRHAHAPRGKTSAFR---LLVSDARTLRTSLGIVILCAVQNFGYYGIM 253 Query: 243 TWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLV 302 WLPT+L S+ ++ + V I G G + L+D IGR+ F++F A + +V Sbjct: 254 IWLPTYLGKTLGFSLTKSALWTSVTILGMMLGIVAFGHLADRIGRKPTFLIFQAGAVAMV 313 Query: 303 LSYTQLIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGA 362 L+Y +L A + A G V+G F++G+ G GA +SE FP+ R + Q +N GRAVG Sbjct: 314 LTYARLTDPLALLWA-GAVMGMFVNGMIGGYGALISEAFPTAARATAQNVLFNLGRAVGG 372 Query: 363 ICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACL-ILPETRGKEL 407 P +VG L+ + I + AG Y L ++A + ++PE +G EL Sbjct: 373 FGPVVVGSLAAAYSFRTAIALL-AGLYVLDMLATMALVPERKGAEL 417