BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0151.p (463 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0075 [GEPR] COG0477 Permeases of the major facilitator superf... 628 e-180 PA0229 [GEPR] COG0477 Permeases of the major facilitator superfa... 595 e-170 STM2654 [GEPR] COG0477 Permeases of the major facilitator superf... 582 e-166 kgtP [GEPR] COG0477 Permeases of the major facilitator superfami... 561 e-160 ECs3454 [GEPR] COG0477 Permeases of the major facilitator superf... 560 e-159 >RSp0075 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 437 Score = 628 bits (1620), Expect = e-180, Method: Compositional matrix adjust. Identities = 306/437 (70%), Positives = 360/437 (82%), Gaps = 3/437 (0%) Query: 4 TPQSSAPSTTSTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDA 63 TP + A P + R+RIFAI+GASSGNLVEWFDFYVY+FC++YFAPAFFP G+ Sbjct: 3 TPAAQASQAVMAP---HDTRRRIFAIVGASSGNLVEWFDFYVYAFCSLYFAPAFFPSGNT 59 Query: 64 TSQLLNTAGVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVLPTYAT 123 T+QL+NTAGVFAAGFLMRPIGGWLFGRIAD+HGR+ +M+ISVLMMCGGSL +AVLP YA Sbjct: 60 TTQLMNTAGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPIYAQ 119 Query: 124 IGAWAPALLLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVL 183 IGA AP LLL+ARLFQGLSVGGEYGTSATYMSEVA GRRGFFASFQYVTLIGGQL A+L Sbjct: 120 IGALAPFLLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALL 179 Query: 184 VLFAMQQWLTKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGL 243 VL +QQ L+ AEL AWGWRIPFV+GA+ ALV++YLR SL ET S +R+ K AGT++G Sbjct: 180 VLVILQQVLSTAELKAWGWRIPFVVGALSALVSLYLRRSLDETQSTASREAKHAGTIRGA 239 Query: 244 LQHKRAFLNVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPI 303 QHK AFL V+GFTAGGSL+FYTFTTYMQKYLVNTAGM+ K A+ VMT ALFVYM LQP+ Sbjct: 240 WQHKGAFLRVIGFTAGGSLIFYTFTTYMQKYLVNTAGMNTKTASNVMTAALFVYMALQPV 299 Query: 304 FGAISDKIGRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISG 363 FGA+SD+IGRR SM+ F ++ T P++ L V++P A L AL I+SFYTSISG Sbjct: 300 FGALSDRIGRRMSMILFGVGAVLFTVPLMRALGSVTNPYAAFGLVTAALAIISFYTSISG 359 Query: 364 LIKAEMFPPEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGVESAFYWYVSALCLVALI 423 LIKAEMFPPEVRA+GVGLSYA+ NA+FGGSAE+VAL KSAG ES FYWYV+ LC V+LI Sbjct: 360 LIKAEMFPPEVRAMGVGLSYAIANAVFGGSAEYVALWFKSAGRESTFYWYVTTLCAVSLI 419 Query: 424 ISLRMPDPQRDGHLKGD 440 +S MPDP ++G+L+ + Sbjct: 420 VSYTMPDPSKEGYLRHE 436 >PA0229 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 432 Score = 595 bits (1534), Expect = e-170, Method: Compositional matrix adjust. Identities = 305/423 (72%), Positives = 357/423 (84%) Query: 18 SAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTAGVFAAG 77 S E RKRIFAI+GASSGNLVEWFDFYVY+FCAIYFAPAFFP + T QLLNTAGVFAAG Sbjct: 9 SNEERRKRIFAIVGASSGNLVEWFDFYVYAFCAIYFAPAFFPSDNPTVQLLNTAGVFAAG 68 Query: 78 FLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVLPTYATIGAWAPALLLLARL 137 FLMRPIGGW+FGRIADKHGRKT+MLISV+MMC GSLA+A +PTYA+IG APALLLLAR+ Sbjct: 69 FLMRPIGGWMFGRIADKHGRKTAMLISVVMMCAGSLAIACMPTYASIGTLAPALLLLARM 128 Query: 138 FQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQWLTKAEL 197 FQGLSVGGEYGTSATYMSEVA G+RGFFASFQYVTLIGGQLLAVLV+ +QQ L++ EL Sbjct: 129 FQGLSVGGEYGTSATYMSEVALKGQRGFFASFQYVTLIGGQLLAVLVVVILQQLLSEDEL 188 Query: 198 MAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAFLNVVGFT 257 AWGWRIPFV+GA+ A++A++LR SL ET+S ++K++GT L +HKRAF V+GFT Sbjct: 189 RAWGWRIPFVIGAITAVIALWLRRSLNETASKSTLERKESGTFAELFKHKRAFFTVLGFT 248 Query: 258 AGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDKIGRRNSM 317 AGGSL+FYTFTTYMQKYLVNTAGM K A+ VMT AL YM++QP+FG +SD+IGR+ SM Sbjct: 249 AGGSLIFYTFTTYMQKYLVNTAGMSAKTASAVMTFALLAYMLMQPLFGMLSDRIGRKTSM 308 Query: 318 LCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFPPEVRAL 377 L F G + T PIL LK VSSP +A L ILAL IVS YTSISGLIKAEMFPPEVRAL Sbjct: 309 LWFGTLGTLCTLPILLALKTVSSPYMAFFLIILALAIVSLYTSISGLIKAEMFPPEVRAL 368 Query: 378 GVGLSYAVGNAIFGGSAEFVALSLKSAGVESAFYWYVSALCLVALIISLRMPDPQRDGHL 437 GVG+SYAVGNAIFGGSAE+VAL LKS G+E+ FYWYVSA+CL+AL++ + +PD ++ +L Sbjct: 369 GVGVSYAVGNAIFGGSAEYVALGLKSVGMENVFYWYVSAMCLLALLVCVSLPDLRKVSYL 428 Query: 438 KGD 440 + Sbjct: 429 NDE 431 >STM2654 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 433 Score = 582 bits (1500), Expect = e-166, Method: Compositional matrix adjust. Identities = 297/423 (70%), Positives = 347/423 (82%), Gaps = 7/423 (1%) Query: 18 SAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTAGVFAAG 77 A E R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QLL TAGVFAAG Sbjct: 14 EAPEMRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTAGVFAAG 73 Query: 78 FLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVLPTYATIGAWAPALLLLARL 137 FLMRPIGGWLFGRIAD+ GRK SMLISV MMC GSL +A LP Y TIG WAPALLL+ARL Sbjct: 74 FLMRPIGGWLFGRIADRRGRKASMLISVCMMCMGSLVIACLPGYDTIGTWAPALLLIARL 133 Query: 138 FQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQWLTKAEL 197 FQGLSVGGEYGTSATYMSEVA GR+GFFASFQYVTLIGGQLLA+LV+ +QQ L AEL Sbjct: 134 FQGLSVGGEYGTSATYMSEVALEGRKGFFASFQYVTLIGGQLLALLVVVILQQVLDDAEL 193 Query: 198 MAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAFLNVVGFT 257 AWGWRIPF LGAV A+VA++LR L ETS R K+AG+LKGL ++++AFL V+GFT Sbjct: 194 RAWGWRIPFALGAVLAVVALWLRRQLDETSKHETRALKEAGSLKGLWRNRKAFLMVLGFT 253 Query: 258 AGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDKIGRRNSM 317 A GSL FYTFTTYMQKYLVNTAGM VA+G+MT AL V+M++QP+FGA+SDKIGRR SM Sbjct: 254 AAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALCVFMLVQPLFGALSDKIGRRTSM 313 Query: 318 LCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFPPEVRAL 377 LCF + T PIL L++V+SP A AL I AL IVSFYTSISG++KAEMFP +VRAL Sbjct: 314 LCFGALATLFTVPILSALQNVTSPYAAFALVICALLIVSFYTSISGILKAEMFPAQVRAL 373 Query: 378 GVGLSYAVGNAIFGGSAEFVALSLKSAGVESAFYWYVSALCLVALIISLRMPDPQRDGHL 437 GVGLSYAV NA+FGGSAE+VALSLKS G+ES+F+WYV+A+ ++A ++SL + H Sbjct: 374 GVGLSYAVANALFGGSAEYVALSLKSVGMESSFFWYVTAMAVLAFLVSLML-------HR 426 Query: 438 KGD 440 KG Sbjct: 427 KGK 429 >kgtP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 432 Score = 561 bits (1447), Expect = e-160, Method: Compositional matrix adjust. Identities = 294/429 (68%), Positives = 348/429 (81%), Gaps = 7/429 (1%) Query: 12 TTSTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTA 71 T + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QLL TA Sbjct: 7 TADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTA 66 Query: 72 GVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVLPTYATIGAWAPAL 131 GVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A LP Y TIG WAPAL Sbjct: 67 GVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTWAPAL 126 Query: 132 LLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQW 191 LLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ +Q Sbjct: 127 LLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVVLQHT 186 Query: 192 LTKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAFL 251 + A L WGWRIPF LGAV A+VA++LR L ETS R K+AG+LKGL +++RAF+ Sbjct: 187 MEDAALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNRRAFI 246 Query: 252 NVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDKI 311 V+GFTA GSL FYTFTTYMQKYLVNTAGM VA+G+MT ALFV+M++QP+ GA+SDKI Sbjct: 247 MVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGALSDKI 306 Query: 312 GRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFP 371 GRR SMLCF + T PIL L++VSSP A L + AL IVSFYTSISG++KAEMFP Sbjct: 307 GRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFP 366 Query: 372 PEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGVESAFYWYVSALCLVALIISLRMPDP 431 +VRALGVGLSYAV NAIFGGSAE+VALSLKS G+E+AF+WYV+ + +VA ++SL + Sbjct: 367 AQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLML--- 423 Query: 432 QRDGHLKGD 440 H KG Sbjct: 424 ----HRKGK 428 >ECs3454 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 432 Score = 560 bits (1444), Expect = e-159, Method: Compositional matrix adjust. Identities = 293/429 (68%), Positives = 348/429 (81%), Gaps = 7/429 (1%) Query: 12 TTSTPLSAAEYRKRIFAILGASSGNLVEWFDFYVYSFCAIYFAPAFFPKGDATSQLLNTA 71 T + L++++ R+RI+AI+GASSGNLVEWFDFYVYSFC++YFA FFP G+ T+QLL TA Sbjct: 7 TADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFFPSGNTTTQLLQTA 66 Query: 72 GVFAAGFLMRPIGGWLFGRIADKHGRKTSMLISVLMMCGGSLAVAVLPTYATIGAWAPAL 131 GVFAAGFLMRPIGGWLFGRIADKHGRK SML+SV MMC GSL +A LP Y TIG WAPAL Sbjct: 67 GVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTWAPAL 126 Query: 132 LLLARLFQGLSVGGEYGTSATYMSEVAPNGRRGFFASFQYVTLIGGQLLAVLVLFAMQQW 191 LLLARLFQGLSVGGEYGTSATYMSEVA GR+GF+ASFQYVTLIGGQLLA+LV+ +Q Sbjct: 127 LLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVVLQHT 186 Query: 192 LTKAELMAWGWRIPFVLGAVGALVAMYLRSSLAETSSAGARKKKDAGTLKGLLQHKRAFL 251 + + L WGWRIPF LGAV A+VA++LR L ETS R K+AG+LKGL +++RAF+ Sbjct: 187 MEDSALREWGWRIPFALGAVLAVVALWLRRQLDETSQQETRALKEAGSLKGLWRNRRAFI 246 Query: 252 NVVGFTAGGSLMFYTFTTYMQKYLVNTAGMDPKVANGVMTGALFVYMILQPIFGAISDKI 311 V+GFTA GSL FYTFTTYMQKYLVNTAGM VA+G+MT ALFV+M++QP+ GA+SDKI Sbjct: 247 MVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFMLIQPLIGALSDKI 306 Query: 312 GRRNSMLCFAFFGMVGTFPILHFLKDVSSPGVAMALAILALTIVSFYTSISGLIKAEMFP 371 GRR SMLCF + T PIL L++VSSP A L + AL IVSFYTSISG++KAEMFP Sbjct: 307 GRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFP 366 Query: 372 PEVRALGVGLSYAVGNAIFGGSAEFVALSLKSAGVESAFYWYVSALCLVALIISLRMPDP 431 +VRALGVGLSYAV NAIFGGSAE+VALSLKS G+E+AF+WYV+ + +VA ++SL + Sbjct: 367 AQVRALGVGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLML--- 423 Query: 432 QRDGHLKGD 440 H KG Sbjct: 424 ----HRKGK 428