BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0117.p (435 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1278 [GEPR] COG0477 Permeases of the major facilitator superf... 391 e-108 PA0458 [GEPR] COG0477 Permeases of the major facilitator superfa... 354 3e-97 STM3887 [GEPR] COG0477 Permeases of the major facilitator superf... 343 4e-94 STM2129 [GEPR] COG0477 Permeases of the major facilitator superf... 336 7e-92 yieO [GEPR] COG0477 Permeases of the major facilitator superfami... 333 6e-91 >RSp1278 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 476 Score = 391 bits (1005), Expect = e-108, Method: Compositional matrix adjust. Identities = 230/438 (52%), Positives = 299/438 (68%), Gaps = 11/438 (2%) Query: 1 MQTLDTTIVNTALPAMARSLAEPVLNMHPVVVAYTLTMASLTPASGWLADRFGTRRVYFA 60 MQTLD TIVNTALPAMARSL+E L M V++AYTLT A L PASGWLADRFGTRR++FA Sbjct: 24 MQTLDATIVNTALPAMARSLSESPLQMQSVIIAYTLTTAMLMPASGWLADRFGTRRMFFA 83 Query: 61 AILLFALGSVLCAMAPTLPMLLAARVIQGLGGSMLLPVGRLAVLRAVPGAQYIAALASIS 120 AI LF++GS+LCA + TL ML+ ARV+QG+GG++L+PVGRL VLR VP Q++ A++ ++ Sbjct: 84 AIFLFSVGSLLCAESRTLTMLIVARVVQGVGGALLMPVGRLTVLRVVPREQFLPAMSFVT 143 Query: 121 IAGQLGPVVGPVLGGWLVESLSWHWIFLINLPVGVLGMGAVLYFLPD---DSLTGTPRFD 177 I G +GP++GP LGGWLVE++SWHWIFLINLPVGV+G L +PD D+ FD Sbjct: 144 IPGLIGPLIGPTLGGWLVEAVSWHWIFLINLPVGVVGALVTLKVMPDVRGDAADAADAFD 203 Query: 178 LFGCALLSACMVAFSLALDVPFD---THRTGWSLGLFALAALTVLVYWRHASVHPRPLFR 234 G +L+ M + S +LD D T L +F LAALT YW HA + LF Sbjct: 204 WAGYLMLAFGMASVSFSLDGLSDLGFRRATVLVLLMFGLAALT--AYWLHAGRAKQALFP 261 Query: 235 LGLFGEPNFSIGLAGNLVCRIGSSAVPFLLPLLLQVRLGYSPLHAGMLLLPAAIAGTIAK 294 LF P+FS+G+ GNL RIG+ +PFL+PLLLQV LGYSP+ AG++++P A+AG AK Sbjct: 262 RALFAIPSFSVGILGNLFARIGAGGMPFLIPLLLQVGLGYSPMQAGLMMVPVAVAGMAAK 321 Query: 295 PWIAPLVKRFGYDRFLLINTAIVGISIVSFALITPGWPLAASIVQLAVFGASNSMQFAAM 354 P LVKR GY L NT ++G+ IVSFAL +P PL IVQLA FG NSMQF +M Sbjct: 322 PLGTWLVKRHGYRHMLFGNTLLLGLMIVSFALSSPQEPLWLRIVQLAAFGTFNSMQFTSM 381 Query: 355 NSVTLKGLRKEDAGSGNSLFSMVQMLAIGLGVTIGGTMVNAFKSEAG---IATNASFQIT 411 N++TL+ L A +GNS+ SMV ML++ LGV G ++N F AG T +F Sbjct: 382 NALTLRDLSGAQASAGNSMLSMVMMLSMSLGVAAAGALLNGFSEYAGGQPADTLGAFHKA 441 Query: 412 FVIVGLITLVSAWVFRKM 429 ++ +GLIT + W+F ++ Sbjct: 442 YICLGLITTAAGWIFAQL 459 >PA0458 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 477 Score = 354 bits (908), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 203/448 (45%), Positives = 282/448 (62%), Gaps = 16/448 (3%) Query: 1 MQTLDTTIVNTALPAMARSLAEPVLNMHPVVVAYTLTMASLTPASGWLADRFGTRRVYFA 60 MQ LD TI+NTALP+MA SL E L M VV+AY LT+A L PASGW+ADRFGTRRV+ Sbjct: 25 MQALDGTILNTALPSMASSLNENPLRMQAVVIAYLLTVALLIPASGWIADRFGTRRVFLG 84 Query: 61 AILLFALGSVLCAMAPTLPMLLAARVIQGLGGSMLLPVGRLAVLRAVPGAQYIAALASIS 120 A+LLF+LGS+LCA++P+L +L+ AR++QG+GG++++PVGRL +LR P + L+ ++ Sbjct: 85 AVLLFSLGSLLCALSPSLELLVGARIVQGVGGALMMPVGRLVILRVYPRQDLVRVLSFVT 144 Query: 121 IAGQLGPVVGPVLGGWLVESLSWHWIFLINLPVGVLGMGAVLYFLPDDSLTGTPRFDLFG 180 I G LGP+ GP LGGWLVE SWHWIFLINLPVG+LG + +PD RFD G Sbjct: 145 IPGLLGPLAGPTLGGWLVEYASWHWIFLINLPVGLLGCLVAMKLMPDLRSPVPSRFDSIG 204 Query: 181 CALLSACMVAFSLALDVPFDTHRTGWSLGLFALAALTVLV-YWRHASVHPRPLFRLGLFG 239 L MV S+AL+ + H + + L + L +L YW A +PLF LF Sbjct: 205 FLLFGGSMVLISIALEGLGELHLSHLRVVLLLIGGLVLLTAYWLRALRIDKPLFPPSLFK 264 Query: 240 EPNFSIGLAGNLVCRIGSSAVPFLLPLLLQVRLGYSPLHAGMLLLPAAIAGTIAKPWIAP 299 F++G+ GNL R+GS A+PFL PLLLQV LGY P AGM ++P A+ +AKP P Sbjct: 265 ARTFAVGILGNLFARLGSGALPFLTPLLLQVGLGYPPSTAGMTMIPLALFAMVAKPMAKP 324 Query: 300 LVKRFGYDRFLLINTAIVGISIVSFALITPGWPLAASIVQLAVFGASNSMQFAAMNSVTL 359 L+ FGY + L+ NT I+G I F L+ P ++ L++ GA NS+QF AMN++TL Sbjct: 325 LLDFFGYRKLLVGNTLILGCLIAGFGLVDQDTPYVWLLLHLSLLGAVNSLQFTAMNTLTL 384 Query: 360 KGLRKEDAGSGNSLFSMVQMLAIGLGVTIGGTMVNAFKSEAGIATN---ASFQITFVIVG 416 L+ +A SGNSL S+V L+I LGV ++ F+++ + +F T+V VG Sbjct: 385 IDLQDSNASSGNSLMSVVVQLSISLGVACAAALLGGFQTDLDTGQDTVLGAFHATYVSVG 444 Query: 417 LITLVSAWVF------------RKMDPR 432 L+++++A +F R++DP Sbjct: 445 LMSMLAAAIFFQLGSEDGRTSPRRVDPE 472 >STM3887 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 475 Score = 343 bits (880), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 186/429 (43%), Positives = 272/429 (63%), Gaps = 6/429 (1%) Query: 1 MQTLDTTIVNTALPAMARSLAEPVLNMHPVVVAYTLTMASLTPASGWLADRFGTRRVYFA 60 MQ LD TI+NTALPA+A SL L M +++YTLT+A L P SGWLADRFGTRRV+ Sbjct: 22 MQALDATILNTALPAIAHSLNRSPLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRVFMV 81 Query: 61 AILLFALGSVLCAMAPTLPMLLAARVIQGLGGSMLLPVGRLAVLRAVPGAQYIAALASIS 120 A+ LF LGS+ CA++ +L L+ RV+QG+GG+M++PV RLA+LRA P ++ + L ++ Sbjct: 82 AVSLFTLGSLACALSSSLSELVIFRVVQGVGGAMMMPVARLALLRAYPRSELLPVLNFVT 141 Query: 121 IAGQLGPVVGPVLGGWLVESLSWHWIFLINLPVGVLGMGAVLYFLPDDSLTGTPR--FDL 178 + G +GP++GPVLGG LV SWHWIFLIN+P+GV G+ ++P+ + TPR FD+ Sbjct: 142 MPGLVGPILGPVLGGVLVTWASWHWIFLINIPIGVAGILYARKYMPNFT---TPRRKFDM 198 Query: 179 FGCALLSACMVAFSLALDVPFDTHRTGWSLGLFALAALTVLV-YWRHASVHPRPLFRLGL 237 G L +V FS +++ + W ++ +L+ Y RHA HP PL L L Sbjct: 199 TGFFLFGLSLVLFSSGMELFGEKIVATWIASAIIFCSIVLLLAYIRHARRHPTPLISLSL 258 Query: 238 FGEPNFSIGLAGNLVCRIGSSAVPFLLPLLLQVRLGYSPLHAGMLLLPAAIAGTIAKPWI 297 F FS+G+AGNL R+G+ VPFL+PL+LQV GY L AG ++ P A+ IAK + Sbjct: 259 FKTRTFSVGIAGNLATRLGTGCVPFLMPLMLQVGFGYPALIAGCMMAPTALGSIIAKSTV 318 Query: 298 APLVKRFGYDRFLLINTAIVGISIVSFALITPGWPLAASIVQLAVFGASNSMQFAAMNSV 357 +++R GY + L+ T +G+ I F+ +P P+ ++ L + G + S QF AMN++ Sbjct: 319 TQVLRRLGYRKTLVGITVFIGLMIAQFSFQSPAMPIWMLVLPLFILGMAMSTQFTAMNTI 378 Query: 358 TLKGLRKEDAGSGNSLFSMVQMLAIGLGVTIGGTMVNAFKSEAGIATNASFQITFVIVGL 417 TL L ++A SGNS+ ++ Q L+I LGV I ++ ++ AG +T F TF+ +G Sbjct: 379 TLADLTDDNASSGNSVLAVTQQLSISLGVAISAAVLRIYEGFAGTSTVEQFHYTFITMGA 438 Query: 418 ITLVSAWVF 426 IT+VSA +F Sbjct: 439 ITIVSALMF 447 >STM2129 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 470 Score = 336 bits (861), Expect = 7e-92, Method: Compositional matrix adjust. Identities = 202/436 (46%), Positives = 285/436 (65%), Gaps = 12/436 (2%) Query: 1 MQTLDTTIVNTALPAMARSLAEPVLNMHPVVVAYTLTMASLTPASGWLADRFGTRRVYFA 60 MQ+LDTTIVNTALP+MA+SL E L+MH VVV+Y LT+A + PASGWLAD+ G R ++FA Sbjct: 21 MQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFA 80 Query: 61 AILLFALGSVLCAMAPTLPMLLAARVIQGLGGSMLLPVGRLAVLRAVPGAQYIAALASIS 120 AI+LF LGS+ CA++ TL L+ ARV+QG+GG+M++PVGRL V++ VP AQY+AA+ ++ Sbjct: 81 AIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVT 140 Query: 121 IAGQLGPVVGPVLGGWLVESLSWHWIFLINLPVGVLGMGAVLYFLPDDSLTGTPRFDLFG 180 + GQ+GP++GP LGG LVE SWHWIFLIN+PVG++G A +P + + T RFDL G Sbjct: 141 LPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMATFMLMP-NYIIETRRFDLPG 199 Query: 181 CALLSACMVAFSLALDVPFDTHRTGWS-LGLFALAALTVLVYWRHASVHPRPLFRLGLFG 239 LL+ M +LALD + W+ GL A A +L+Y HA + LF L LF Sbjct: 200 FLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFR 259 Query: 240 EPNFSIGLAGNLVCRIGSSAVPFLLPLLLQVRLGYSPLHAGMLLLPAAIAGTIAKPWIAP 299 P FS+GL G+ RIGS +PF+ P+ LQ+ LG+SP HAG++++P + K + Sbjct: 260 TPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQ 319 Query: 300 LVKRFGYDRFLLINT---AIVGISIVSFALITPGWPLAASIVQLAVFGASNSMQFAAMNS 356 +V RFGY R L+ T A+V + +S AL+ GW +V L G NS +F++MN+ Sbjct: 320 IVNRFGYRRVLVATTLGLALVSLLFMSVALL--GWYYLLPLVLLLQ-GMVNSARFSSMNT 376 Query: 357 VTLKGLRKEDAGSGNSLFSMVQMLAIGLGVTIGGTMVNAF-KSEAGI---ATNASFQITF 412 +TLK L A SGNSL SM+ L++ +GVTI G ++ F + GI AT+ F T+ Sbjct: 377 LTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTW 436 Query: 413 VIVGLITLVSAWVFRK 428 + + +I + A +F + Sbjct: 437 LCMAVIIALPAIIFAR 452 >yieO [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 475 Score = 333 bits (853), Expect = 6e-91, Method: Compositional matrix adjust. Identities = 180/427 (42%), Positives = 266/427 (62%), Gaps = 2/427 (0%) Query: 1 MQTLDTTIVNTALPAMARSLAEPVLNMHPVVVAYTLTMASLTPASGWLADRFGTRRVYFA 60 MQ LD TI+NTALPA+A SL L M +++YTLT+A L P SGWLADRFGTRR++ Sbjct: 22 MQALDATILNTALPAIAHSLNRSPLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTL 81 Query: 61 AILLFALGSVLCAMAPTLPMLLAARVIQGLGGSMLLPVGRLAVLRAVPGAQYIAALASIS 120 A+ LF LGS+ CA++ +LP L+ RVIQG+GG+M++PV RLA+LRA P + + L ++ Sbjct: 82 AVSLFTLGSLACALSNSLPQLVVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVA 141 Query: 121 IAGQLGPVVGPVLGGWLVESLSWHWIFLINLPVGVLGMGAVLYFLPDDSLTGTPRFDLFG 180 + G +GP++GPVLGG LV +WHWIFLIN+P+G+ G+ +P+ + T RFD+ G Sbjct: 142 MPGLVGPILGPVLGGVLVTWATWHWIFLINIPIGIAGLLYARKHMPNFT-TARRRFDITG 200 Query: 181 CALLSACMVAFSLALDVPFDTHRTGW-SLGLFALAALTVLVYWRHASVHPRPLFRLGLFG 239 L +V FS +++ + W +L + + +L+Y HA P PL L LF Sbjct: 201 FLLFGLSLVLFSSGIELFGEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFK 260 Query: 240 EPNFSIGLAGNLVCRIGSSAVPFLLPLLLQVRLGYSPLHAGMLLLPAAIAGTIAKPWIAP 299 FSIG+ GN+ R+G+ VPFL+PL+LQV GY AG ++ P A+ IAK + Sbjct: 261 TRTFSIGIVGNIATRLGTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQ 320 Query: 300 LVKRFGYDRFLLINTAIVGISIVSFALITPGWPLAASIVQLAVFGASNSMQFAAMNSVTL 359 +++R GY L+ T I+G+ I F+L +P + I+ L + G + S QF AMN++TL Sbjct: 321 VLRRLGYRHTLVGITVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITL 380 Query: 360 KGLRKEDAGSGNSLFSMVQMLAIGLGVTIGGTMVNAFKSEAGIATNASFQITFVIVGLIT 419 L ++A SGNS+ ++ Q L+I LGV + ++ ++ G T F TF+ +G+IT Sbjct: 381 ADLTDDNASSGNSVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIIT 440 Query: 420 LVSAWVF 426 + SA +F Sbjct: 441 VASAAMF 447