BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0081.p (503 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0952 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso R... 530 e-150 NMB1368 [LKJ] COG0513 Superfamily II DNA and RNA helicases Nme N... 441 e-123 NMA1580 [LKJ] COG0513 Superfamily II DNA and RNA helicases NmA N... 441 e-123 RSc0539 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso R... 347 5e-95 rhlE [LKJ] COG0513 Superfamily II DNA and RNA helicases Eco Esch... 338 2e-92 >RSc0952 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso Ralstonia solanacearum Length = 608 Score = 530 bits (1366), Expect = e-150, Method: Compositional matrix adjust. Identities = 258/406 (63%), Positives = 323/406 (79%), Gaps = 8/406 (1%) Query: 6 LGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSLHQLAD 65 LGL+ I +AL E YT PTPVQ +AIPA +SG+DLLV+SQTGSGKTAAFMLP++ ++++ Sbjct: 35 LGLDERIARALGELNYTQPTPVQAQAIPACLSGRDLLVTSQTGSGKTAAFMLPAIQRISE 94 Query: 66 LPQAPQAART--PNQERQATRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYGAYM 123 P+ PQ R P Q R +G RPR PA+P +LVLTPTRELALQVTTAT +YG ++ Sbjct: 95 QPE-PQRPRADGPQQ-----RVKGRRPRPAPAKPSLLVLTPTRELALQVTTATAQYGRHL 148 Query: 124 RRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEADRM 183 RR+ SILGGMPYPKQ+ +L+R P+I++ATPGRL+DH++SG+ID S L +LV DEADRM Sbjct: 149 RRIVCASILGGMPYPKQLDMLARMPDIIIATPGRLLDHIDSGRIDLSALDMLVFDEADRM 208 Query: 184 LDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPATIQIASSSTRHENIM 243 LDMGF DDIE IV ATPA+RQ ++FSAT+D + +A+R+ P I+IA++ +I Sbjct: 209 LDMGFADDIEAIVGATPASRQMLMFSATMDRRIEQLAERMMREPQRIEIAAARIDQSHIE 268 Query: 244 QRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHGDMH 303 +R+HF DDLSHK +LLDHLLRD ++ QA++FTATKRDAD++A+RL GF+A ALHGDMH Sbjct: 269 ERLHFTDDLSHKQQLLDHLLRDATLKQAIVFTATKRDADSLAERLTETGFSAGALHGDMH 328 Query: 304 QGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTGRAG 363 QGARNRTL +LRRGQ+R+LVATDVAARGIDVP ITHV N+DLPK AEDYVHRIGRTGRAG Sbjct: 329 QGARNRTLTALRRGQLRVLVATDVAARGIDVPDITHVVNFDLPKQAEDYVHRIGRTGRAG 388 Query: 364 RNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKSAAPRS 409 R+G+AI+LVNH + Q +RIERF + I VVEG EPK+S PRS Sbjct: 389 RSGIAINLVNHGDTFQWRRIERFVDRRIDATVVEGLEPKRSPKPRS 434 >NMB1368 [LKJ] COG0513 Superfamily II DNA and RNA helicases Nme Neisseria meningitidis MC58 Length = 462 Score = 441 bits (1135), Expect = e-123, Method: Compositional matrix adjust. Identities = 241/483 (49%), Positives = 310/483 (64%), Gaps = 41/483 (8%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 + F L L+ +I+ A++ GY SPTP+Q +AIP A+ G+D++ S+QTGSGKTAAF+LP+L Sbjct: 3 IKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIMASAQTGSGKTAAFLLPTL 62 Query: 61 HQLADLPQAPQAARTPNQERQATRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 +L R E+P P+ LVLTPTRELA QV Y Sbjct: 63 QKLT--------------------KRSEKP---GKGPRALVLTPTRELAAQVEKNALAYA 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 MR R VSI+GG + Q + LS+ +++VATPGRL+D M+SGK+DF +L++L+LDEA Sbjct: 100 KNMRWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFERLEVLILDEA 159 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPATIQIASSSTRHE 240 DRMLDMGFIDDIE IV ATP+ RQT+LFSAT DG VG +A+++T +P I++ + + Sbjct: 160 DRMLDMGFIDDIETIVEATPSDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQGK 219 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 I +++ + DD+ HKNRLLDH+LRD +IDQ VIFT+TK + IAD L GFAA LHG Sbjct: 220 -IEEQLLYCDDMRHKNRLLDHILRDANIDQCVIFTSTKAMTEVIADELYEKGFAANCLHG 278 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 DM QG RNRTL LR+G+ ++LVATDVAARGIDVP ITHV NYDLPK AEDYVHRIGRTG Sbjct: 279 DMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRIGRTG 338 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEP---KKSA-------APRSP 410 RAGR G+AI+ E ++V +IE++ + +P +EG EP +KSA Sbjct: 339 RAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKGKGGWGD 398 Query: 411 RKPGGWRPGDGRSNSGPRFGAGNREGGGHREG----GFGGNREGGFGGNREGGHREGGFG 466 RK GGWR S G FG R G +EG GF E GF G R+ G G G Sbjct: 399 RKSGGWRGDHKPSKEG--FGGKTRGEGFKKEGFKRDGFKKTGE-GFKGKRKAGDSFAGKG 455 Query: 467 GNR 469 R Sbjct: 456 ERR 458 >NMA1580 [LKJ] COG0513 Superfamily II DNA and RNA helicases NmA Neisseria meningitidis Z2491 Length = 462 Score = 441 bits (1133), Expect = e-123, Method: Compositional matrix adjust. Identities = 241/483 (49%), Positives = 309/483 (63%), Gaps = 41/483 (8%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 + F L L+ +I+ A++ GY SPTP+Q +AIP A+ G+D++ S+QTGSGKTAAF+LP+L Sbjct: 3 IKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIMASAQTGSGKTAAFLLPTL 62 Query: 61 HQLADLPQAPQAARTPNQERQATRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 +L R E+P P+ LVLTPTRELA QV Y Sbjct: 63 QRLT--------------------KRSEKP---GKGPRALVLTPTRELAAQVEKNALAYA 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 MR R VSI+GG + Q + LS+ +++VATPGRL+D M+SGK+DF++L++L+LDEA Sbjct: 100 KNMRWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFARLEVLILDEA 159 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPATIQIASSSTRHE 240 DRMLDMGFIDDIE IV ATP RQT+LFSAT DG VG +A+++T +P I++ + + Sbjct: 160 DRMLDMGFIDDIETIVEATPEDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQGK 219 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 I +++ + DD+ HKNRLLDH+LRD IDQ VIFT+TK + IAD L GFAA LHG Sbjct: 220 -IEEQLLYCDDMRHKNRLLDHILRDADIDQCVIFTSTKAMTEVIADELYEKGFAANCLHG 278 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 DM QG RNRTL LR+G+ ++LVATDVAARGIDVP ITHV NYDLPK AEDYVHRIGRTG Sbjct: 279 DMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRIGRTG 338 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEP---KKSA-------APRSP 410 RAGR G+AI+ E ++V +IE++ + +P +EG EP +KSA Sbjct: 339 RAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKGKGGWGD 398 Query: 411 RKPGGWRPGDGRSNSGPRFGAGNREGGGHREG----GFGGNREGGFGGNREGGHREGGFG 466 RK GGWR S G FG R G +EG GF E GF G R+ G G G Sbjct: 399 RKSGGWRGDHKPSKEG--FGGKTRGEGFKKEGFKRDGFKKTGE-GFKGKRKAGDSFAGKG 455 Query: 467 GNR 469 R Sbjct: 456 ERR 458 >RSc0539 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso Ralstonia solanacearum Length = 540 Score = 347 bits (889), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 204/451 (45%), Positives = 270/451 (59%), Gaps = 32/451 (7%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 M+F LGL+ +++A+ E GY PTP+Q +AIPA + G DLL +QTG+GKTA F LP L Sbjct: 1 MSFSELGLSDKLVRAVAELGYAEPTPIQRQAIPAILKGGDLLAGAQTGTGKTAGFTLPLL 60 Query: 61 HQLADLPQAPQAARTPNQERQATRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 H+L+ + P +TP+ R RA LVLTPTRELA QV + YG Sbjct: 61 HRLSAV--QPNKVQTPHGMRYPIRA--------------LVLTPTRELAAQVEESVRAYG 104 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 Y+ ++ + + GG+ Q+ L R +I+VATPGRL+DH+ ID S +++LVLDEA Sbjct: 105 KYLP-LKSMVMFGGVGINPQIDALKRGVDIVVATPGRLLDHVGQRTIDLSHIELLVLDEA 163 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPATIQIASSSTRHE 240 DRMLDMGFI DI KI+ P RQ +LFSAT + +A R+ + PA I++A +T E Sbjct: 164 DRMLDMGFIHDIRKILNILPPKRQNLLFSATFSDDIRALADRLLDQPALIEVARRNTTAE 223 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 + QR++ VD K LL L+ D Q ++FT TK A+ +A++L G A A+HG Sbjct: 224 TVEQRIYPVDR-ERKRELLAKLVSDNDWHQVLVFTRTKHGANRLAEQLTRDGIPALAIHG 282 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 + Q AR R L+ + G +R+LVATD+AARGID+ + HV N+DLP EDYVHRIGRTG Sbjct: 283 NKSQSARTRALSEFKAGTLRVLVATDIAARGIDIDQLPHVVNFDLPNVPEDYVHRIGRTG 342 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKSAAPR-------SPRKP 413 RAG G AISLV E ++ IER K+ +P V+ GFEP + AP S R P Sbjct: 343 RAGAQGEAISLVCVDEHGLLRDIERLIKRELPRTVLAGFEPDPTIAPEPIPNGRNSARAP 402 Query: 414 GGWRPGDGRSNSGPRFGAGN---REGGGHRE 441 R G GRS PR AGN RE RE Sbjct: 403 ---RQGGGRSQP-PRQAAGNAAPREPRAPRE 429 >rhlE [LKJ] COG0513 Superfamily II DNA and RNA helicases Eco Escherichia coli K12 Length = 454 Score = 338 bits (866), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 178/404 (44%), Positives = 251/404 (62%), Gaps = 23/404 (5%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 M+F++LGL+P I++A+ E GY PTP+Q++AIPA + G+DL+ S+QTG+GKTA F LP L Sbjct: 1 MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMASAQTGTGKTAGFTLPLL 60 Query: 61 HQLADLPQAPQAARTPNQERQATRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 L R P+ A+G RP + L+LTPTRELA Q+ Y Sbjct: 61 QHLI--------TRQPH-------AKGRRP------VRALILTPTRELAAQIGENVRDYS 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 Y+ +R + + GG+ QM L ++LVATPGRL+D + Q++ILVLDEA Sbjct: 100 KYLN-IRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEA 158 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPATIQIASSSTRHE 240 DRMLDMGFI DI +++ PA RQ +LFSAT + +A+++ +NP I++A +T + Sbjct: 159 DRMLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD 218 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 + Q VHFVD K LL H++ + Q ++FT TK A+ +A++LN G +AA+HG Sbjct: 219 QVTQHVHFVDK-KRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG 277 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 + QGAR R L + G +R+LVATD+AARG+D+ + HV NY+LP EDYVHRIGRTG Sbjct: 278 NKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIGRTG 337 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKS 404 RA G A+SLV E ++ IE+ K+ IP + G+EP S Sbjct: 338 RAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPS 381