BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0030.p (400 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4117 [T] COG4251 Bacteriophytochrome (light-regulated signal t... 127 7e-29 BS_resE_4 [T] COG0642 Signal transduction histidine kinase Bsu B... 117 4e-26 slr1324_2 [T] COG0642 Signal transduction histidine kinase Syn S... 101 4e-21 CAC3219 [T] COG0642 Signal transduction histidine kinase Cac Clo... 97 5e-20 BH1581 [T] COG0642 Signal transduction histidine kinase Bha Baci... 97 7e-20 >PA4117 [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase) Pae Pseudomonas aeruginosa Length = 728 Score = 127 bits (318), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 76/242 (31%), Positives = 126/242 (52%), Gaps = 7/242 (2%) Query: 159 LAESLARYSKLLDQSRNLFLAILGHDLRNPLGATIQGAQIILLAEDIDDRHRKIAARIYN 218 L E ++ +D+ R +A+LGHDLRNPL + A ++ D R ++ I Sbjct: 489 LMELCLNHAAEVDRMRQRLIAVLGHDLRNPLQSISMAAALL---SSSDTRTTELRQHISA 545 Query: 219 SGQRMGKLVADLLDYTRTHLGTGLPLHLTSVNIGEIAQSVVEEISTSHPDREVTLKTSGD 278 S RM +LV+ +LD +R G GL ++ ++ ++ + +V E ++P + + Sbjct: 546 SSSRMERLVSQILDMSRLQSGIGLTVNPVDTDVSQLVRQIVCETDVAYPGLVIEIAIDPQ 605 Query: 279 LKGKWDRERVAQAISNLLGNAVQHGLAEEPIRVEITAAQDEVIVSINNKAPRIPEEKLQS 338 ++ D +R AQ +NLL NA HGL P+ V +T DEV +S+ N+ + E +L + Sbjct: 606 VRAVVDPDRYAQVAANLLSNARHHGLPGRPVLVTLTRQGDEVCLSVLNETSGLSEAQLAN 665 Query: 339 IFNPLVRLAADADEPAKQSGSMGLGLYIVREVASAHGGSVTVGSSADEGTTFTIRLPKDQ 398 +F P R +AD + +G+GLYI + +A AH G + V D+ TF +RLP Q Sbjct: 666 LFEPFKRESADNQ---RNRNGLGIGLYISQAIAQAHQGRIDV-DCRDDVITFCLRLPVRQ 721 Query: 399 EQ 400 + Sbjct: 722 AE 723 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Bsu Bacillus subtilis Length = 269 Score = 117 bits (294), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 78/233 (33%), Positives = 128/233 (54%), Gaps = 14/233 (6%) Query: 170 LDQSRNLFLAILGHDLRNPLGATIQG---AQIILLAEDIDDRHRKIAARIYNSGQRMGKL 226 LD+ R F+A + H+LR P+ + +QG A + +A +DR ++IA IY+ RMG+L Sbjct: 41 LDKLREDFIANVSHELRTPI-SMLQGYSEAIVDDIASSEEDR-KEIAQIIYDESLRMGRL 98 Query: 227 VADLLDYTRTHLG-TGLPLHLTSVNIGEIAQSVVEEISTSHPDREVTLKTSGDLKGK--- 282 V DLLD R G TGL H +N+ E + ++ + S ++ + L L + Sbjct: 99 VNDLLDLARMESGHTGL--HYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFM 156 Query: 283 WDRERVAQAISNLLGNAVQHGLAEEPIRVEITAAQDEVIVSINNKAPRIPEEKLQSIFNP 342 +D +++ Q +NL+ NA++H A + + + + +D + + I + IPEE L IF Sbjct: 157 FDEDKMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFER 216 Query: 343 LVRLAADADEPAKQSGSMGLGLYIVREVASAHGGSVTVGSSADEGTTFTIRLP 395 + AD ++G+ GLGL IV+ + AH GS+TV S D+GTTF+ +P Sbjct: 217 FYK--ADKARTRGRAGT-GLGLAIVKNIVEAHNGSITVHSRIDKGTTFSFYIP 266 >slr1324_2 [T] COG0642 Signal transduction histidine kinase Syn Synechocystis Length = 267 Score = 101 bits (251), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 73/253 (28%), Positives = 127/253 (50%), Gaps = 22/253 (8%) Query: 156 DQALAESLARYSKLLDQSR------NLFLAILGHDLRNPLGATIQGAQIILLAEDIDDRH 209 +Q L+ S+ R + L +++ + F+++L HD RNPL + A ++ E+ DR Sbjct: 11 NQILSASIKRQERELSEAKAANKLKSEFVSMLSHDFRNPLNTILLSAGLL---EESGDRL 67 Query: 210 RKIAARIYNSGQR-----MGKLVADLLDYTRTHLGTGLPLHLTSVNIGEIAQSVVEEIST 264 K Y + R + +L++++L +T G L S+++ Q ++ ++ Sbjct: 68 SKGQQHNYFNMIRTAIKDLDELLSEVLLLGKTENGQ-LSCQFESLDLLYFCQDLMRLVNN 126 Query: 265 SH-PDREVTLKTSGDLK-GKWDRERVAQAISNLLGNAVQHGLAEEPIRVEITAAQDEVIV 322 + R + T G+L+ G WD + I NLL NA+++ + PI ++ A +I Sbjct: 127 AQRQPRPIHFHTQGNLQQGVWDAHLLRHIICNLLSNAIKYSPSPTPILFDVIAEGKTMIF 186 Query: 323 SINNKAPRIPEEKLQSIFNPLVRLAADADEPAKQSGSMGLGLYIVREVASAHGGSVTVGS 382 + ++ IP + + +FNP R AD +G+ GLGL IV+ A+ HGG VTV S Sbjct: 187 RVTDQGIGIPPQAMAELFNPFFR----ADNVEGVTGT-GLGLAIVQRCANIHGGEVTVES 241 Query: 383 SADEGTTFTIRLP 395 EG+ F +RLP Sbjct: 242 KEGEGSCFAVRLP 254 >CAC3219 [T] COG0642 Signal transduction histidine kinase Cac Clostridium acetobutylicum Length = 475 Score = 97.4 bits (241), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 125/232 (53%), Gaps = 12/232 (5%) Query: 171 DQSRNLFLAILGHDLRNPLGATIQGAQIILLAEDI-DDRHRKIAARIYNSGQRMGKLVAD 229 +++R F++ + H++R+P+ +I+G +L I ++ R + Y+ R+ +LV D Sbjct: 250 EKNRREFISNVSHEIRSPI-TSIKGFIGGMLDGVIPKEKERYYLSLTYDEINRLTRLVND 308 Query: 230 LLDYTRTHLGTGLPLHLTSVNIGEIAQSVVEEISTSHPDREVTLKTSGDLKGKW---DRE 286 LLD + G L L+LT ++I EI + V + T ++++ + + + D++ Sbjct: 309 LLDLSSIEAG-HLKLNLTKIDINEIIRFTVLKFETKIKEKKLNVDVCFNNDKVYVIADKD 367 Query: 287 RVAQAISNLLGNAVQHGLAEEPIRVEITAAQDEVIVSINNKAPRIPEEKLQSIFNPLVRL 346 R++Q ++NL+ NAV++ AE I++ ++ ++I N P+IPEE I++ + Sbjct: 368 RISQVVTNLIDNAVKYVYAEGEIKISTKERYNKAYITIYNNGPQIPEEDFNHIWDRFYK- 426 Query: 347 AADADEPAKQSGSMGLGLYIVREVASAHGGSVTVGSSADEGT--TFTIRLPK 396 +D+ S GLGL IVR + + HG + V + + G TFT++L K Sbjct: 427 ---SDKARTTKMSTGLGLPIVRSILTEHGQDINVINKKEGGVEFTFTLKLAK 475 >BH1581 [T] COG0642 Signal transduction histidine kinase Bha Bacillus halodurans Length = 594 Score = 97.1 bits (240), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 120/233 (51%), Gaps = 15/233 (6%) Query: 171 DQSRNLFLAILGHDLRNPLGATIQGAQIILLAEDI---DDRHRKIAARIYNSGQRMGKLV 227 D+ R F+A + H+LR P+ + +QG ++ +DI D +++A IY+ RMG+LV Sbjct: 363 DKLRKDFIANVSHELRTPI-SMLQGYSEAII-DDIAGTDQEKKELAKIIYDESLRMGRLV 420 Query: 228 ADLLDYTRTHLGTGLPLHLTSVNIGEIAQSVVEEISTSHPDREVTLK--TSGDLKGK--- 282 +LLD R G + L + + + + + ++++TL GD +GK Sbjct: 421 NELLDLARMEAG-HIDLSYEEIEVKTFCERITRKFQGLAKEQQLTLDFIYRGD-EGKRIQ 478 Query: 283 WDRERVAQAISNLLGNAVQHGLAEEPIRVEITAAQDEVIVSINNKAPRIPEEKLQSIFNP 342 D +R+ Q ++NLL NA++H +++ ++ V + + + IPEE L +F Sbjct: 479 VDPDRLEQVLTNLLSNAIRHTDPGGTVQLACHVMENGVKIDVTDTGTGIPEEDLPYVFER 538 Query: 343 LVRLAADADEPAKQSGSMGLGLYIVREVASAHGGSVTVGSSADEGTTFTIRLP 395 + AD +SG+ GLGL IV+ + AH G ++V S EGTTFT P Sbjct: 539 FYK--ADKARTRGRSGT-GLGLAIVKNIVDAHSGEISVHSKQQEGTTFTAFFP 588