BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0014.0025.p (395 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 287 3e-77 RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 281 1e-75 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 254 2e-67 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 254 2e-67 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 240 5e-63 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 287 bits (735), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 169/356 (47%), Positives = 242/356 (67%), Gaps = 4/356 (1%) Query: 1 VLSAALFGLAAGALTSGPLADRYGRRKILLLSVLVMGVACMGSAFAGNLQELTILRFLTG 60 V+SAAL G+ GAL SGPLADRYGR+ +L+ +V + G+ + SA++ N+++L LRFLTG Sbjct: 69 VMSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTG 128 Query: 61 LGLGAAMPNAVTLTSEYSPAARRAMLTNAMFCGFPLGAALGGFLAAWMIPLWGWRSVLML 120 LGLGAAMPNA TL SEY+P +++L +MFCGF LG A GGF++A +IPL+GW S+L+L Sbjct: 129 LGLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLL 188 Query: 121 GGAAPLLLLLVMLPNLPESVRHMVAKGYAAERIGAVLRRISSSAAAFNRFTLAETGPQGE 180 GG PL+L +V+L LPES R++V + +ER+ VL I+ + A R + P+ + Sbjct: 189 GGLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALAR---SFHVPEQQ 245 Query: 181 APTGKSGIALLFEPRYLVGTCMLWLAYFMGLVIFYALVNWMPVLFKDAGLAPKTATLIAA 240 ++ A++F Y GT +LWL YFMGLVI Y L +W+P L +D+G + + A I A Sbjct: 246 TVQARNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGA 305 Query: 241 LFPLGGV-GAILFGWLMDRYNANRVIAIGFAATAVAVFAIGQAAGNVGVLTVVVFVAGTL 299 LF GGV A+ GW MDR+N ++VI + + V + +GQ+ G V +L +V +AG Sbjct: 306 LFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLAGMC 365 Query: 300 MNTAQSSLPALAAAYYPTRGRATGVAWMLGVGRFGGIAGSFLVAELTRRQLGFSEV 355 +N AQS++P+LAA +YPT+GRATGV+WMLG+GRFG I G+++ A L F +V Sbjct: 366 INGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWNFEQV 421 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 281 bits (720), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 172/386 (44%), Positives = 234/386 (60%), Gaps = 7/386 (1%) Query: 1 VLSAALFGLAAGALTSGPLADRYGRRKILLLSVLVMGVACMGSAFAGNLQELTILRFLTG 60 V SA L GL GAL GPLADR GR++ LL +V G+A + SAFA ++ L LRFLTG Sbjct: 65 VFSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTG 124 Query: 61 LGLGAAMPNAVTLTSEYSPAARRAMLTNAMFCGFPLGAALGGFLAAWMIPLWGWRSVLML 120 LGLG AMPNA+ LTSEY P RRA LT MFCGF LG+ GG +AA ++P +GWRSVL+ Sbjct: 125 LGLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLF 184 Query: 121 GGAAPLLLLLVMLPNLPESVRHMVAKGYAAERIGAVLRRISS-SAAAFNRFTLAETGPQG 179 GG PLLLL VM+ LPESVR++VAKG + +G +L RI+ RF L ET +G Sbjct: 185 GGVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKG 244 Query: 180 EAPTGKSGIALLFEPRYLVGTCMLWLAYFMGLVIFYALVNWMPVLFKDAGLAPKTATLIA 239 AP S + LF P + GT +LW +FM L+I Y + NW+P L G+A A+ IA Sbjct: 245 -AP--GSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIA 301 Query: 240 ALFPLGG-VGAILFGWLMDRYNANRVIAIGFAATAVAVFAIGQAAGNVGVLTVVVFVAGT 298 ++ LGG VGA++ G +MDRY A V+ + A + G + G +L + V G Sbjct: 302 VMYQLGGTVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTGVSQGT--MLAIAVTGVGF 359 Query: 299 LMNTAQSSLPALAAAYYPTRGRATGVAWMLGVGRFGGIAGSFLVAELTRRQLGFSEVFAV 358 ++ +Q A AA +YPT R TG++W LG+GR G + G+ + L +GF +F + Sbjct: 360 CISGSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLL 419 Query: 359 VAVAALVSTVALLVKQASDRNRPDGG 384 VAV A ++++A+ + A R+ G Sbjct: 420 VAVPAAIASLAIFLCGAQARHVETQG 445 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 254 bits (649), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 147/373 (39%), Positives = 214/373 (57%), Gaps = 13/373 (3%) Query: 16 SGPLADRYGRRKILLLSVLVMGVACMGSAFAGNLQELTILRFLTGLGLGAAMPNAVTLTS 75 GPL+DR+GR++++ L V + G + SAF+ +LQ L LRFLTGLGLG AMPN +T+TS Sbjct: 77 CGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLGGAMPNTITMTS 136 Query: 76 EYSPAARRAMLTNAMFCGFPLGAALGGFLAAWMIPLWGWRSVLMLGGAAPLLLLLVMLPN 135 EY PA RR L MFCGF LG+A GG ++A ++P+ GW +L+LGG PL+L + +L Sbjct: 137 EYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLPLMLFVALLVV 196 Query: 136 LPESVRHMVAKGYAAERIGAVLRRISSSAAAFNRFTLAETGPQGEAPTGKSGIALLFEPR 195 LPES R V + I + I+ F L E+ A K I LF R Sbjct: 197 LPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIES-----ASVTKGSIRQLFMGR 251 Query: 196 YLVGTCMLWLAYFMGLVIFYALVNWMPVLFKDAGLAPKTATLIAALFPLGG-VGAILFGW 254 L T MLW+ +FM L+I Y L +WMP L G+ + A+ + A F +GG +GA+ G Sbjct: 252 QLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLGALALGV 311 Query: 255 LMDRYNANRVIAIGFAATAVAVFAIGQAAGNVGVLTVVVFVAGTLMNTAQSSLPALAAAY 314 LMD++N RV+ + +A A+ + IG + + ++ + +F G ++ +Q L AL A Sbjct: 312 LMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTATL 371 Query: 315 YPTRGRATGVAWMLGVGRFGGIAGSFLVAELTRRQLGFSEVFAVVAVAALVSTVAL---- 370 YPT+ RATGV+W +GR G I GS + F +F ++AV A +S V L Sbjct: 372 YPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAVMLTLLI 431 Query: 371 -LVKQASDRNRPD 382 +V+Q++ + PD Sbjct: 432 TVVRQST--SVPD 442 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 254 bits (649), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 147/373 (39%), Positives = 214/373 (57%), Gaps = 13/373 (3%) Query: 16 SGPLADRYGRRKILLLSVLVMGVACMGSAFAGNLQELTILRFLTGLGLGAAMPNAVTLTS 75 GPL+DR+GR++++ L V + G + SAF+ +LQ L LRFLTGLGLG AMPN +T+TS Sbjct: 77 CGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLGGAMPNTITMTS 136 Query: 76 EYSPAARRAMLTNAMFCGFPLGAALGGFLAAWMIPLWGWRSVLMLGGAAPLLLLLVMLPN 135 EY PA RR L MFCGF LG+A GG ++A ++P+ GW +L+LGG PL+L + +L Sbjct: 137 EYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLPLMLFVALLVV 196 Query: 136 LPESVRHMVAKGYAAERIGAVLRRISSSAAAFNRFTLAETGPQGEAPTGKSGIALLFEPR 195 LPES R V + I + I+ F L E+ A K I LF R Sbjct: 197 LPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIES-----ASVTKGSIRQLFMGR 251 Query: 196 YLVGTCMLWLAYFMGLVIFYALVNWMPVLFKDAGLAPKTATLIAALFPLGG-VGAILFGW 254 L T MLW+ +FM L+I Y L +WMP L G+ + A+ + A F +GG +GA+ G Sbjct: 252 QLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLGALALGV 311 Query: 255 LMDRYNANRVIAIGFAATAVAVFAIGQAAGNVGVLTVVVFVAGTLMNTAQSSLPALAAAY 314 LMD++N RV+ + +A A+ + IG + + ++ + +F G ++ +Q L AL A Sbjct: 312 LMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTATL 371 Query: 315 YPTRGRATGVAWMLGVGRFGGIAGSFLVAELTRRQLGFSEVFAVVAVAALVSTVAL---- 370 YPT+ RATGV+W +GR G I GS + F +F ++AV A +S V L Sbjct: 372 YPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAVMLTLLI 431 Query: 371 -LVKQASDRNRPD 382 +V+Q++ + PD Sbjct: 432 TVVRQST--SVPD 442 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 240 bits (612), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 153/360 (42%), Positives = 213/360 (59%), Gaps = 6/360 (1%) Query: 4 AALFGLAAGALTSGPLADRYGRRKILLLSVLVMGVACMGSAFAGNLQELTILRFLTGLGL 63 A LFGL G++ GP+ADR+GR+ +LL+SVLV GVA + A + +L L +LRFLTGLGL Sbjct: 70 AGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGL 129 Query: 64 GAAMPNAVTLTSEYSPAARRAMLTNAMFCGFPLGAALGGFLAAWMIPLWGWRSVLMLGGA 123 G AMP +TL++EYSP R +L + GF G ALGG +AA ++P++GWR VL+ GG Sbjct: 130 GGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGV 189 Query: 124 APLLLLLVMLPNLPESVRHMVAKGYAAERIGAVLRRISSSAAAFNRFTLAETGPQGEAP- 182 PL+LL V+ +PESV+ + + A+ + ++ RI+ + + Q AP Sbjct: 190 TPLVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIAGHDHGDGVTFIGDRPAQEGAPF 249 Query: 183 TGKSGIALLFEPRYLVGTCMLWLAYFMGLVIFYALVNWMPVLFKDAGLAPKTATLIAALF 242 G++ LF T +LW A+F L +FY L +W+PV+ +D GL A + A+ Sbjct: 250 PGRN----LFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMV 305 Query: 243 PLGG-VGAILFGWLMDRYNANRVIAIGFAATAVAVFAIGQAAGNVGVLTVVVFVAGTLMN 301 PLGG +GAI LMDR + R + + A+AV AIG A GNV LT VVFV G + Sbjct: 306 PLGGTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIA 365 Query: 302 TAQSSLPALAAAYYPTRGRATGVAWMLGVGRFGGIAGSFLVAELTRRQLGFSEVFAVVAV 361 AQ+ + LAA YPT RATGV+W LGVGR G I GS + L +F ++A+ Sbjct: 366 GAQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQTLFGIIAL 425