BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0179.p (259 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SSO0102 [R] COG0596 Predicted hydrolases or acyltransferases (al... 99 1e-20 DR0791 [R] COG0596 Predicted hydrolases or acyltransferases (alp... 89 1e-17 AF1706 [R] COG0596 Predicted hydrolases or acyltransferases (alp... 82 2e-15 BMEII0638 [R] COG0596 Predicted hydrolases or acyltransferases (... 76 7e-14 SMb20579 [R] COG0596 Predicted hydrolases or acyltransferases (a... 76 1e-13 >SSO0102 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Sso Sulfolobus solfataricus Length = 231 Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 68/241 (28%), Positives = 108/241 (44%), Gaps = 15/241 (6%) Query: 21 LCIHGLGGSSNTWTPILPALA-GRKVIRLDLPGSGRSKLPAQALTIEAYVLAVRQVLKAL 79 + IH L GS +W ++P L+ V+ DL G GRS P IE + +R++L L Sbjct: 1 MLIHHLAGSYKSWKFVIPKLSLDNTVVAYDLRGHGRSSTPNSPYNIEDHSNDLRRLLVQL 60 Query: 80 KIESVDILAHSMGTIVAQHFAVAYPDSVTSLVLFGPLVAPP--EPARPAIRARAELARQG 137 IE ++ HS+G+++A +A+ YP + LVL G L P E +R + Sbjct: 61 GIEKPVLIGHSIGSLIAIDYALKYP--IEKLVLIGALYRAPSSEVYEKYVRIAVNFGMRA 118 Query: 138 AEKVQEIADAIVAGATSKETKASNPMALTLVRESVMRQPPEGYAQSCEALASAQSAPIEE 197 + + ET ASN A + E P GY + E L A+ E Sbjct: 119 LAEYRRFHKEFT------ETLASNYQAWNSLLEVYEETTPIGYKNAVEGLLKAKDYSDEL 172 Query: 198 IAV--QTLLVTGDQDGVAPAANVNAMAQRIRGSKVLVLEGCGHWTTFEKTDACIKAIKEA 255 + + +TL+V G DG+ N+N ++ ++ ++G GH+ FE + IK Sbjct: 173 MGINAKTLIVYGTYDGL--IVNLNVFKNNMKNVEIKTIDGYGHFLNFENPLLLSEIIKNF 230 Query: 256 L 256 L Sbjct: 231 L 231 >DR0791 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Dra Deinococcus radiodurans Length = 305 Score = 89.0 bits (219), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 125/256 (48%), Gaps = 13/256 (5%) Query: 8 DIAVEVEGDGAPVLCIHG--LGGSSNTWTPILPALAGRKVIRLDLPGSGRSKL-PAQALT 64 + + G G P+L IHG L G ++ +G +VI +DLPG G+SKL P Q ++ Sbjct: 52 QVYYKATGSGQPLLLIHGYPLNGELFKNNRMM---SGYRVITVDLPGFGKSKLAPGQTVS 108 Query: 65 IEAYVLAVRQVLKALKIESVDILAHSMGTI-VAQHFAVAYPDSVTSLVLFGPLVAPPEPA 123 IE Y + + A+K++ + SMG + + Q + +A P+ L+L P A Sbjct: 109 IENYAQTMVGFMDAMKLDKAVVGGMSMGGMTLLQMYKIA-PERFKGLILIDTTAEPAGIA 167 Query: 124 RPAI-RARAELARQGAEKVQEIADAIVAGATSKETKASNPMALTLVRESVMRQPPEGYAQ 182 A+ R A+ A+Q + V + D ++ + E++ P + + + + EG Sbjct: 168 EAAMWRGTAQQAQQ--KGVASLVDLLMPRMLTGESRMKMPNQVAHLGNLIKQASVEGAVG 225 Query: 183 SCEALASAQSAP--IEEIAVQTLLVTGDQDGVAPAANVNAMAQRIRGSKVLVLEGCGHWT 240 + ALAS A + I V TL+V G +D V M + IRGSK++++ G GH + Sbjct: 226 AGNALASRPDANPVLPTIKVPTLIVAGLEDNVTAPELQMKMNKAIRGSKLVLIPGAGHAS 285 Query: 241 TFEKTDACIKAIKEAL 256 TFEK A A+ L Sbjct: 286 TFEKAGAMNAAVANWL 301 >AF1706 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Afu Archaeoglobus fulgidus Length = 238 Score = 81.6 bits (200), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 59/204 (28%), Positives = 95/204 (46%), Gaps = 8/204 (3%) Query: 15 GDGAPVLCIHGLGGSSNTWTPILPALAGR-KVIRLDLPGSGRSKLPAQALTIEAYVLAVR 73 G+G P++ IHGLG WT + +V+ LDL G G S +P +++++E + V+ Sbjct: 25 GEGEPLILIHGLGDCIEGWTFQYDDFSKHFRVVALDLRGFGMSDVP-ESISVEDFARDVK 83 Query: 74 QVLKALKIESVDILAHSMGTIVAQHFAVAYPDSVTSLVLFGPLVAPPEPARPAIRARAEL 133 ++ L IE ++L SMG +V F YP+ V SLVL L P+ R R +L Sbjct: 84 NLIDHLGIERANLLGLSMGGVVCMEFYRQYPEMVKSLVLANTLHKLPDAGRAMFEQRLKL 143 Query: 134 ARQGAEKVQEIADAIVAGATSKETKASNPMALTLVRESVMRQPPEGYAQSCEALASAQSA 193 + Q IA+ I + ++ P LV+ + + E Y + L Sbjct: 144 LESSPDMTQ-IAEFIAEMSIHQD----RPELKELVKTIIRKNNKEFYTKVTAELGRINYE 198 Query: 194 P-IEEIAVQTLLVTGDQDGVAPAA 216 + +I V TL++T + D P A Sbjct: 199 DLLPKIEVPTLVITAEFDVTTPPA 222 >BMEII0638 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Bme Brucella melitensis Length = 267 Score = 76.3 bits (186), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 79/264 (29%), Positives = 110/264 (41%), Gaps = 17/264 (6%) Query: 6 IDDIAVEVE----GDGAPVLC-IHGLGGSSNTWTPILPALAGRKVIRL--DLPGSGRSKL 58 ++DI V + G+ PVL I+ LG W + L G V L D G G S + Sbjct: 6 VNDIVVHYDLRWNGNDKPVLVFINSLGTDFRIWNKVRARL-GHDVSTLVYDKRGHGLSDI 64 Query: 59 PAQALTIEAYVLAVRQVLKALKIESVDILAHSMGTIVAQHFAVAYPDSVTSLVLFGPL-- 116 TIE + +L L I I S+G ++AQ A PD V LVL Sbjct: 65 GKTPYTIELLAQDLIALLDRLSIHKAVICGLSVGGLIAQGLYAARPDLVAGLVLSNTAHK 124 Query: 117 VAPPEPARPAIRARAELARQGAEKVQEIADAIVAGATSKETKASNPMALTLVRESVMRQP 176 + PE AR + Q + I DA + + + + A RQP Sbjct: 125 IGTPE----MWNARIDAIMQNG--LASILDATMPRWFTAAYRRPDNAAYQAYCNMFTRQP 178 Query: 177 PEGYAQSCEALASAQ-SAPIEEIAVQTLLVTGDQDGVAPAANVNAMAQRIRGSKVLVLEG 235 EGYA +C AL A +A +I+V V GDQDG P V +A I G+ + Sbjct: 179 LEGYAATCAALRDADFTAAAHKISVPVRCVAGDQDGSTPPTLVQELASLIPGAVFSQIAN 238 Query: 236 CGHWTTFEKTDACIKAIKEALSNN 259 GH E+ DA +++ LS+N Sbjct: 239 SGHIPCVEQPDAYTALLRDFLSHN 262 >SMb20579 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) Sme Sinorhizobium meliloti Length = 268 Score = 75.9 bits (185), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 68/260 (26%), Positives = 111/260 (42%), Gaps = 11/260 (4%) Query: 6 IDDIAVEVEGDGA-----PVLCIHGLGGSSNTWTPILPALAGRKVIRL-DLPGSGRSKLP 59 I+D+ + GA ++ I+ LG W ++ LAG I L D G G S + Sbjct: 6 INDVTIHYRVVGAVTEKPALVFINSLGTDFRIWRDVVLRLAGDFAIVLYDKRGHGLSDIG 65 Query: 60 AQALTIEAYVLAVRQVLKALKIESVDILAHSMGTIVAQHFAVAYPDSVTSLVLFGPLVAP 119 +IE + + +L L ++ + S+G ++AQ PD V +LVL G Sbjct: 66 QVPYSIEDHATDLAGLLDRLAVKQAIVCGLSVGGLIAQSLYGRRPDLVRALVLSGT---- 121 Query: 120 PEPARPAIRARAELARQGAEKVQEIADAIVAGATSKETKASNPMALTLVRESVMRQPPEG 179 A + A ++ +AD ++ + + +A T R ++RQP G Sbjct: 122 AHKIGTVEFWDARITAIEAHGIEAVADGVLERWFTPAFRRPENLAFTGYRNMLVRQPVPG 181 Query: 180 YAQSCEALASAQ-SAPIEEIAVQTLLVTGDQDGVAPAANVNAMAQRIRGSKVLVLEGCGH 238 Y +C A+ A + IAV L V GDQDG P V + A I G++ V+ G GH Sbjct: 182 YVGTCAAIRDADFTEAAGRIAVPVLCVVGDQDGSTPPDLVRSTADLIPGARFEVIRGAGH 241 Query: 239 WTTFEKTDACIKAIKEALSN 258 E+ +A ++ + Sbjct: 242 IPCVEQPEALWSVLRRFFRS 261