BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0160.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 275 1e-73 PA2006 [GEPR] COG0477 Permeases of the major facilitator superfa... 250 5e-66 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 249 7e-66 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 246 1e-64 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 245 1e-64 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 275 bits (704), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 167/438 (38%), Positives = 243/438 (55%), Gaps = 10/438 (2%) Query: 7 IQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMARFGPIFS 66 I V +D + QWS + C + +DGFDT +G +APA++++ I A G +FS Sbjct: 8 IDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTVFS 67 Query: 67 AGLLGMLVGAMILGPLADRFGRKTMVIASTLAFGSMSLLTALAASHDDLLLLRFLTGIGL 126 AGL G++VGA+I GPLADR GRK ++ + AFG S+L+A A S L+ LRFLTG+GL Sbjct: 68 AGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGLGL 127 Query: 127 GGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGA 186 GGA+PNA+AL SEY P R + + CG LG+ GGIV + L+P GW +V + GG Sbjct: 128 GGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFGGV 187 Query: 187 LPIAVALFALVFMPESARFLLVRGKHRARLQALMRRIAP-ELGADQDL---AAPPPQAPG 242 +P+ + + +PES R+L+ +G A + L+ RIAP ++ D APG Sbjct: 188 IPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKGAPG 247 Query: 243 VPVAELFRHGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVTVGITAISCFSAG 302 PV +LF T+LLW +FM+L+++Y + +W+P ++ + + + G Sbjct: 248 SPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMYQLG 307 Query: 303 GVLGSLLQGWLMNALGVRRTLVLELALYALLALGLANWPQSEWNVIVASSLMGVVIQGAQ 362 G +G+L+ G +M+ L L A L L Q I + +G I G+Q Sbjct: 308 GTVGALVIGRMMDRYPATVVLCCTYGLGAGF-LVLTGVSQGTMLAIAVTG-VGFCISGSQ 365 Query: 363 AGLNVLATEIYPTAMRATGIGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAV 422 G N A + YPTA R TGI +ALGIGR+GS+CG L G ++L + + +FL+ PA Sbjct: 366 IGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAVPAA 425 Query: 423 IAGLAIVF----NRRAET 436 IA LAI R ET Sbjct: 426 IASLAIFLCGAQARHVET 443 >PA2006 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 450 Score = 250 bits (638), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 169/420 (40%), Positives = 243/420 (57%), Gaps = 6/420 (1%) Query: 13 IDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMARFGPIFSAGLLGM 72 +DARPV QW + L+ V DG+D Q +G + P +++E G+ A FGP+FSA L G+ Sbjct: 12 LDARPVSRYQWLLLLLLALLLVTDGYDAQVLGYVVPTLAQEWGLDKAAFGPVFSANLFGL 71 Query: 73 LVGAMILGPLADRFGRKTMVIASTLAFGSMSLLTALAASHDDLLLLRFLTGIGLGGALPN 132 VG++++ PLADRFG + +++ L + S+++L A S + L+L RF+ GIG+GGA+P+ Sbjct: 72 TVGSLLVTPLADRFGIRRVLLCCVLIYASLTVLMVFAGSLESLMLARFVCGIGMGGAMPS 131 Query: 133 ALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGALPIAVA 192 A+AL +EYSP R ++V CG G GG V + + GW AVF+ GG P+ + Sbjct: 132 AMALMAEYSPPRLRTLMVTLAACGFSFGGAAGGFVAAAFMDGFGWQAVFLAGGVTPLLLF 191 Query: 193 LFALVFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLAAPPPQAPGVPVAELFRHG 252 F L+F+PES LL ARL+ L R+AP A A + V ELFRHG Sbjct: 192 PFLLLFLPESLPRLLRDAPPYARLRQLSERMAPGWQPPPAEAD-AEPAASLTVLELFRHG 250 Query: 253 RWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVTVGITAISCFSAGGVLGSLLQGW 312 + T+LLW +F++L++LYF+VSW+P++L + A S F G LG++L W Sbjct: 251 YARPTLLLWATFFVSLILLYFMVSWLPSLLQESGLTRNAANLATSMFLFAGTLGAMLLAW 310 Query: 313 LMNAL--GVRRTLVLELALYAL-LALGLANWPQSEWNVIVASSLMGVVIQGAQAGLNVLA 369 L + L VR + L LGL N Q W + + G I G Q LN A Sbjct: 311 LADRLRSKVRLLAAILAGAALFTLLLGL-NHDQPRWLLAFVFA-AGFCIIGGQLTLNAFA 368 Query: 370 TEIYPTAMRATGIGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAGLAIV 429 + YP +RATG G+ALG+GR GSI GPL GSL+LG + V++IF++ PA +A L I+ Sbjct: 369 SNFYPAQVRATGTGWALGVGRFGSILGPLFGSLLLGMHISVENIFMLAAIPAGLAALLIL 428 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 249 bits (637), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 151/410 (36%), Positives = 234/410 (57%), Gaps = 3/410 (0%) Query: 7 IQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMARFGPIFS 66 + V I+A+P+ QW + C LI LDG DT +G +APA++++ GI A GP+ S Sbjct: 12 LDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPVMS 71 Query: 67 AGLLGMLVGAMILGPLADRFGRKTMVIASTLAFGSMSLLTALAASHDDLLLLRFLTGIGL 126 A L+GM+ GA+ GPLADR+GRK +++A+ FG SL +A + + + LL LRFLTG+GL Sbjct: 72 AALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGLGL 131 Query: 127 GGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGA 186 G A+PNA L SEY+P R ++V ++ CG LG GG V++ L+P GWH++ ++GG Sbjct: 132 GAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLGGL 191 Query: 187 LPIAVALFALVFMPESARFLLVRGKHRARLQALMRRIAP-ELGADQDLAAPPPQAPGVP- 244 LP+ +A+ L +PESAR+L+VR + R++ ++ IAP ++ + P Q Sbjct: 192 LPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVPEQQTVQARN 251 Query: 245 -VAELFRHGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVTVGITAISCFSAGG 303 A +F T+LLW+ YFM LV++Y + SW+P ++ + + + F GG Sbjct: 252 VFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGALFQFGG 311 Query: 304 VLGSLLQGWLMNALGVRRTLVLELALYALLALGLANWPQSEWNVIVASSLMGVVIQGAQA 363 VL ++ GW M+ + + L L + A + + L G+ I GAQ+ Sbjct: 312 VLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLAGMCINGAQS 371 Query: 364 GLNVLATEIYPTAMRATGIGFALGIGRIGSICGPLAGSLMLGWQMDVKHI 413 + LA YPT RATG+ + LGIGR G+I G G+ +LG + + + Sbjct: 372 AMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWNFEQV 421 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 246 bits (627), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 149/420 (35%), Positives = 228/420 (54%), Gaps = 1/420 (0%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMARFGPIFSA 67 + +IDA PVG +QW I C L+ +LDGFDT IG +AP + + P+F A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVIASTLAFGSMSLLTALAASHDDLLLLRFLTGIGLG 127 GLL + GA++ GPL+DRFGRK ++ FG++SL +A + L+ LRFLTG+GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 GA+PN + + SEY P R +V + CG LG+ GGIV++ L+P GWH + ++GG L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 188 PIAVALFALVFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLA-APPPQAPGVPVA 246 P+ + + LV +PES R+ + R +A + + I E D + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIR 245 Query: 247 ELFRHGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVTVGITAISCFSAGGVLG 306 +LF + T++LW+ +FM+L+++Y + SWMP +L + + F GG LG Sbjct: 246 QLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLG 305 Query: 307 SLLQGWLMNALGVRRTLVLELALYALLALGLANWPQSEWNVIVASSLMGVVIQGAQAGLN 366 +L G LM+ R L L A+ A+ + + W + +A G+ I G+Q GLN Sbjct: 306 ALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLN 365 Query: 367 VLATEIYPTAMRATGIGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAGL 426 L +YPT RATG+ ++ IGR G+I G L+G +M+ +F + PA I+ + Sbjct: 366 ALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAV 425 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 245 bits (626), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 150/420 (35%), Positives = 229/420 (54%), Gaps = 1/420 (0%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMARFGPIFSA 67 + +IDA PVG +QW I C L+ +LDGFDT IG +AP + + P+F A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVIASTLAFGSMSLLTALAASHDDLLLLRFLTGIGLG 127 GLLG+ GA++ GPL+DRFGRK ++ FG++SL +A + L+ LRFLTG+GLG Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 GA+PN + + SEY P R +V + CG LG+ GGIV++ L+P GWH + ++GG L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 188 PIAVALFALVFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLA-APPPQAPGVPVA 246 P+ + + LV +PES R+ + R +A + + I E D + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIR 245 Query: 247 ELFRHGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVTVGITAISCFSAGGVLG 306 +LF + T++LW+ +FM+L+++Y + SWMP +L + + F GG LG Sbjct: 246 QLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLG 305 Query: 307 SLLQGWLMNALGVRRTLVLELALYALLALGLANWPQSEWNVIVASSLMGVVIQGAQAGLN 366 +L G LM+ R L L A+ A+ + + W + +A G+ I G+Q GLN Sbjct: 306 ALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLN 365 Query: 367 VLATEIYPTAMRATGIGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAGL 426 L +YPT RATG+ ++ IGR G+I G L+G +M+ +F + PA I+ + Sbjct: 366 ALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAV 425