BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0007.p (1046 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0928 [P] COG3696 Putative silver efflux pump Rso Ralstonia so... 1588 0.0 ybdE [P] COG3696 Putative silver efflux pump Eco Escherichia col... 1530 0.0 ZybdE [P] COG3696 Putative silver efflux pump EcZ Escherichia co... 1525 0.0 ECs0613 [P] COG3696 Putative silver efflux pump Ecs Escherichia ... 1525 0.0 aq_1122 [P] COG3696 Putative silver efflux pump Aae Aquifex aeol... 878 0.0 >RSp0928 [P] COG3696 Putative silver efflux pump Rso Ralstonia solanacearum Length = 1047 Score = 1588 bits (4111), Expect = 0.0, Method: Compositional matrix adjust. Identities = 777/1039 (74%), Positives = 897/1039 (86%), Gaps = 1/1039 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MI +LI S+R+RFLVL L WGLWA+++TP+DALPDLSDVQVIIRT + GQAPQI Sbjct: 1 MIARLIFASIRNRFLVLLTTALLTAWGLWAVRSTPLDALPDLSDVQVIIRTPFPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPL TTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTD+YWARSRVLEYLNQVQ R Sbjct: 61 VENQVTYPLTTTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDLYWARSRVLEYLNQVQSR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP +AK +LGPDATGVGW+YEYALVD+TG+HDLAQLR+LQDWFL++ELK+LPNVAEVA+V Sbjct: 121 LPVAAKPALGPDATGVGWVYEYALVDKTGRHDLAQLRALQDWFLRFELKALPNVAEVASV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQ+QVVL P KL AYN++Q KV+ A+K ANQETGGSVLE+ E EYMVRASGYLKTL Sbjct: 181 GGMVKQFQVVLQPDKLRAYNLSQAKVLAALKGANQETGGSVLELGEAEYMVRASGYLKTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DFR IPLAT GV V+LGDVA +Q GPEMRRGIAEL+G+GE GGVI++RSGKNA ET Sbjct: 241 DDFRQIPLATSDAGVAVRLGDVATVQLGPEMRRGIAELDGQGEVAGGVIVMRSGKNALET 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK++L L+KSLP GVE+VPVYDRS LI RA+DNL+HKL+EEFIVVA+VC +FL+HL Sbjct: 301 IEAVKAKLAALRKSLPVGVEIVPVYDRSALIHRAVDNLTHKLIEEFIVVALVCVVFLFHL 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RSALVAIVSLPLG++ AF+VMRYQGVNANIMSLGGIAIA+GAMVDAAVVMIENAHKH+E Sbjct: 361 RSALVAIVSLPLGVLAAFLVMRYQGVNANIMSLGGIAIAVGAMVDAAVVMIENAHKHLER 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W HPG L G W VIGEAAAEVGP LFF LLIITLSFIPVFTLEAQEGRLF PLAF Sbjct: 421 WHEAHPGHALAGHERWGVIGEAAAEVGPALFFSLLIITLSFIPVFTLEAQEGRLFSPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTY+MA AAGLSVTL+P+LMGY+IRG+IPSE SNPL+RWLIR Y+P+L VL PR T+ Sbjct: 481 TKTYSMAAAAGLSVTLVPVLMGYLIRGQIPSEQSNPLSRWLIRLYQPVLARVLAYPRATV 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 AIA + L T WPI R GGEF+P +DE DLLYMPSALPGLSA KAA+LLQQTDRLIKTVP Sbjct: 541 AIALVLLAATAWPILRTGGEFMPPLDEGDLLYMPSALPGLSAGKAAQLLQQTDRLIKTVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVA+VFGKAGRA++ATDPAP+EMFETTI+FKPRDQWRPGMT KLV+ELDRVVKVPGLSN Sbjct: 601 EVATVFGKAGRADTATDPAPMEMFETTIRFKPRDQWRPGMTTDKLVDELDRVVKVPGLSN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IWVPPIRNR+DMLATGIKSP+G+KV+GT L ID+ QIE K VPGV+SALAERLSG Sbjct: 661 IWVPPIRNRIDMLATGIKSPVGIKVAGTDLQQIDRLTTQIEAAVKTVPGVTSALAERLSG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY+DVDI R+ A YGLNI DVQSIV+SAIGG+NVGE ++GLAR+P+++RYPR+ RDS+ Sbjct: 721 GRYIDVDIHRMAAGRYGLNIEDVQSIVASAIGGDNVGEVVDGLARFPVNLRYPRDYRDSV 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 E+LR LPI+T GQQI L VA +++ GPPML+SENAR SGW+YVD+RGRDL S V D+ Sbjct: 781 EQLRSLPIVTDRGQQIVLSDVADIRVVSGPPMLRSENARLSGWVYVDIRGRDLRSAVRDM 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 +AAV+ V + G ++++SGQFEYLERA+ +LK+VVP TL+IIFVLLYL F R DEA LI Sbjct: 841 QAAVAKAVPMPAGYALSWSGQFEYLERASTKLKVVVPFTLLIIFVLLYLVFGRIDEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 M +LP AL+GG W LY GYNLSVA VGFIALAGV+AEFGV+MLLYLKQA + R+++G Sbjct: 901 MGTLPLALIGGFWLLYGLGYNLSVAGVVGFIALAGVAAEFGVIMLLYLKQAWTERQERGQ 960 Query: 961 TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGMIT 1020 T + +LE AI+EGAVLRVRPKAMTVAV+LAGLIPI+W G GSEVM RIAAPMVGGM+T Sbjct: 961 TTTDALLE-AIQEGAVLRVRPKAMTVAVVLAGLIPIMWSHGTGSEVMQRIAAPMVGGMVT 1019 Query: 1021 APLLSMFVIPAAYRLMRGR 1039 APLLS+ V+PA Y L+R R Sbjct: 1020 APLLSLLVVPAVYLLLRRR 1038 >ybdE [P] COG3696 Putative silver efflux pump Eco Escherichia coli K12 Length = 1047 Score = 1530 bits (3962), Expect = 0.0, Method: Compositional matrix adjust. Identities = 743/1038 (71%), Positives = 877/1038 (84%), Gaps = 2/1038 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MIE +I+ S+ +RFLVL G LFL WG W + TPVDALPDLSDVQVII+T+Y GQAPQI Sbjct: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPL TTMLSVPGAKTVRG+S FGDS+VYV+FEDGTD YWARSRVLEYLNQVQG+ Sbjct: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGK 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP A LGPDATGVGWIYEYALVDR+G+HDLA LRSLQDWFLKYELK++P+VAEVA+V Sbjct: 121 LPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVASV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GG+VK+YQVV+DP +LA Y I+ +V A+ +NQE GGS +E+AE EYMVRASGYL+TL Sbjct: 181 GGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DF +I L NGVPV L DVA +Q GPEMRRGIAELNGEGE GGV+ILRSGKNARE Sbjct: 241 DDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIAELNGEGEVAGGVVILRSGKNAREV 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK +LE LK SLP GVE+V YDRSQLIDRAIDNLS KLLEEFIVVAVVC LFLWH+ Sbjct: 301 IAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHV 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RSALVAI+SLPLG+ IAFIVM +QG+NANIMSLGGIAIA+GAMVDAA+VMIENAHK +EE Sbjct: 361 RSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEE 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W+H+HP L W+VI +A+ EVGP LF LLIITLSFIP+FTLE QEGRLFGPLAF Sbjct: 421 WQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMAGAA L++ +IPILMGY IRGKIP E+SNPLNR+LIR Y PLL VL P+TTL Sbjct: 481 TKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTL 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 +AAL++LT LWP++++GGEFLPQ++E DLLYMPS LPG+SA++AA +LQ+TD+LI +VP Sbjct: 541 LVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVA VFGK G+AE+ATD APLEM ETTIQ KP++QWRPGMT K++ ELD V++PGL+N Sbjct: 601 EVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLAN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 +WVPPIRNR+DML+TGIKSPIG+KVSGT LADID A+QIE+VA+ VPGV+SALAERL G Sbjct: 661 LWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY++V+I+R AA YG+ +ADVQ V+SA+GG VGET+EG+ARYPI++RYP+ RDS Sbjct: 721 GRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSP 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 + LR LPILT QQITL VA +K+S GP MLK+ENARP+ WIY+D R RD+ SVV DL Sbjct: 781 QALRQLPILTPMKQQITLADVADIKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDL 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 + A++ KV+L PG S+A+SGQFE LERAN +LKL+VP TLMIIFVLLYL FRR EA LI Sbjct: 841 QKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 ++S+PFALVGGIW L+ G++LSVATG GFIALAGV+AEFGVVML+YL+ A+ A Sbjct: 901 ISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAVPSLNN 960 Query: 961 --TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGM 1018 T S L++A+ GAVLRVRPKAMTVAVI+AGL+PILWG+GAGSEVMSRIAAPM+GGM Sbjct: 961 PQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGM 1020 Query: 1019 ITAPLLSMFVIPAAYRLM 1036 ITAPLLS+F+IPAAY+LM Sbjct: 1021 ITAPLLSLFIIPAAYKLM 1038 >ZybdE [P] COG3696 Putative silver efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1045 Score = 1525 bits (3948), Expect = 0.0, Method: Compositional matrix adjust. Identities = 743/1038 (71%), Positives = 875/1038 (84%), Gaps = 4/1038 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MIE +I+ S+ +RFLVL G LFL WG W + TPVDALPDLSDVQVII+T+Y GQAPQI Sbjct: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPL TTMLSVPGAKTVRG+S FGDS+VYV+FEDGTD YWARSRVLEYLNQVQG+ Sbjct: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGK 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP A LGPDATGVGWIYEYALVDR+G+HDLA LRSLQDWFLKYELK++P+VAEVA+V Sbjct: 121 LPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVASV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GG+VK+YQVV+DP +LA Y I+ +V A+ +NQE GGS +E+AE EYMVRASGYL+TL Sbjct: 181 GGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DF +I L NGVPV L DVA IQ GPEMRRGIAELNGE VGGV+ILRSGKNARE Sbjct: 241 DDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIAELNGE--VVGGVVILRSGKNAREV 298 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK +LE LK SLP GVE+V YDRSQLIDRAIDNLS KLLEEFIVVAVVC LFLWH+ Sbjct: 299 IAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHV 358 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RSALVAI+SLPLG+ IAFIVM +QG+NANIMSLGGIAIA+GAMVDAA+VMIENAHK +EE Sbjct: 359 RSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEE 418 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W+H+HP L W+VI A+ EVGP LF LLIITLSFIP+FTLE QEGRLFGPLAF Sbjct: 419 WQHQHPDATLDNKTRWQVITNASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAF 478 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMAGAA L++ +IPILMGY IRGKIP E+SNPLNR+LIR Y PLL VL P+TTL Sbjct: 479 TKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTL 538 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 +AAL++LT LWP++++GGEFLPQ++E DLLYMPS LPG+SA++AA +LQ+TD+LI +VP Sbjct: 539 LVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVP 598 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVA VFGK G+AE+ATD APLEM ETTIQ KP++QWRPGMT K++ ELD V++PGL+N Sbjct: 599 EVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLAN 658 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 +WVPPIRNR+DML+TGIKSPIG+KVSGT LADID A+QIE+VA+ VPGV+SALAERL G Sbjct: 659 LWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEG 718 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY++V+I+R AA YG+ +ADVQ V+SA+GG VGET+EG+ARYPI++RYP+ RDS Sbjct: 719 GRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSP 778 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 + LR LPILT QQITL VA +K+S GP MLK+ENARP+ WIY+D R RD+ SVV DL Sbjct: 779 QALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDL 838 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 + A++ KV+L PG S+A+SGQFE LERAN +LKL+VP TLMIIFVLLYL FRR EA LI Sbjct: 839 QKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLI 898 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 ++S+PFALVGGIW L+ G++LSVATG GFIALAGV+AEFGVVML+YL+ A+ A Sbjct: 899 ISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNN 958 Query: 961 --TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGM 1018 T S L++A+ GAVLRVRPKAMTVAVI+AGL+PILWG+GAGSEVMSRIAAPM+GGM Sbjct: 959 PQTFSEQKLDEALHHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGM 1018 Query: 1019 ITAPLLSMFVIPAAYRLM 1036 ITAPLLS+F+IPAAY+LM Sbjct: 1019 ITAPLLSLFIIPAAYKLM 1036 >ECs0613 [P] COG3696 Putative silver efflux pump Ecs Escherichia coli O157:H7 Length = 1045 Score = 1525 bits (3948), Expect = 0.0, Method: Compositional matrix adjust. Identities = 743/1038 (71%), Positives = 875/1038 (84%), Gaps = 4/1038 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MIE +I+ S+ +RFLVL G LFL WG W + TPVDALPDLSDVQVII+T+Y GQAPQI Sbjct: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPL TTMLSVPGAKTVRG+S FGDS+VYV+FEDGTD YWARSRVLEYLNQVQG+ Sbjct: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGK 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP A LGPDATGVGWIYEYALVDR+G+HDLA LRSLQDWFLKYELK++P+VAEVA+V Sbjct: 121 LPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVASV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GG+VK+YQVV+DP +LA Y I+ +V A+ +NQE GGS +E+AE EYMVRASGYL+TL Sbjct: 181 GGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DF +I L NGVPV L DVA IQ GPEMRRGIAELNGE VGGV+ILRSGKNARE Sbjct: 241 DDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIAELNGE--VVGGVVILRSGKNAREV 298 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK +LE LK SLP GVE+V YDRSQLIDRAIDNLS KLLEEFIVVAVVC LFLWH+ Sbjct: 299 IAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHV 358 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RSALVAI+SLPLG+ IAFIVM +QG+NANIMSLGGIAIA+GAMVDAA+VMIENAHK +EE Sbjct: 359 RSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEE 418 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W+H+HP L W+VI A+ EVGP LF LLIITLSFIP+FTLE QEGRLFGPLAF Sbjct: 419 WQHQHPDATLDNKTRWQVITNASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAF 478 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMAGAA L++ +IPILMGY IRGKIP E+SNPLNR+LIR Y PLL VL P+TTL Sbjct: 479 TKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTL 538 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 +AAL++LT LWP++++GGEFLPQ++E DLLYMPS LPG+SA++AA +LQ+TD+LI +VP Sbjct: 539 LVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVP 598 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVA VFGK G+AE+ATD APLEM ETTIQ KP++QWRPGMT K++ ELD V++PGL+N Sbjct: 599 EVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLAN 658 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 +WVPPIRNR+DML+TGIKSPIG+KVSGT LADID A+QIE+VA+ VPGV+SALAERL G Sbjct: 659 LWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEG 718 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY++V+I+R AA YG+ +ADVQ V+SA+GG VGET+EG+ARYPI++RYP+ RDS Sbjct: 719 GRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSP 778 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 + LR LPILT QQITL VA +K+S GP MLK+ENARP+ WIY+D R RD+ SVV DL Sbjct: 779 QALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDL 838 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 + A++ KV+L PG S+A+SGQFE LERAN +LKL+VP TLMIIFVLLYL FRR EA LI Sbjct: 839 QKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLI 898 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 ++S+PFALVGGIW L+ G++LSVATG GFIALAGV+AEFGVVML+YL+ A+ A Sbjct: 899 ISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNN 958 Query: 961 --TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGM 1018 T S L++A+ GAVLRVRPKAMTVAVI+AGL+PILWG+GAGSEVMSRIAAPM+GGM Sbjct: 959 PQTFSEQKLDEALHHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGM 1018 Query: 1019 ITAPLLSMFVIPAAYRLM 1036 ITAPLLS+F+IPAAY+LM Sbjct: 1019 ITAPLLSLFIIPAAYKLM 1036 >aq_1122 [P] COG3696 Putative silver efflux pump Aae Aquifex aeolicus Length = 1050 Score = 878 bits (2268), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/1061 (42%), Positives = 674/1061 (63%), Gaps = 51/1061 (4%) Query: 2 IEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQIV 61 +E+ + LR+R +LF +FL +G ++LK TP+DA+PDLSDVQVII + + GQ PQ++ Sbjct: 1 MERFTEILLRNRLPILFISIFLLFYGYYSLKKTPIDAIPDLSDVQVIIYSEWIGQIPQVI 60 Query: 62 ENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGRL 121 E+Q+TYPL T M+ VP KTVRGYSF S V+V+FEDGTD+YWARSRVLE L+ ++ +L Sbjct: 61 EDQLTYPLVTNMMGVPKVKTVRGYSFPNFSLVFVIFEDGTDLYWARSRVLEKLSSIRSQL 120 Query: 122 PPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATVG 181 P A+ LGPDATGVGW+Y+Y LV + + L +L +LQ++++KY L S+P+VAEVA+VG Sbjct: 121 PQDARIELGPDATGVGWVYKYVLVSK--KRTLEELWALQNFYIKYALLSIPDVAEVASVG 178 Query: 182 GMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTLA 241 G K+Y++++ P KL Y I+ ++ AIK+ N ETGG +E+ E EY++RA GY+K Sbjct: 179 GFEKEYRILVKPEKLYQYGISLGELYRAIKRTNVETGGKYVEINEKEYLIRAVGYVKNRE 238 Query: 242 DFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARETI 301 + +A R+GVP++L DVA + P R G+A+ NG G++V G++++R G +A + I Sbjct: 239 EIEKTVVAE-RDGVPIRLEDVAKVVEVPAFRMGVADFNGMGDTVAGIVVMRFGADAYKVI 297 Query: 302 VAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHLR 361 VK +LEE+KK LP V+V+ YDRS LI+ AI+NL KL+EE +VV ++ G+FL+H+R Sbjct: 298 QRVKEKLEEVKKGLPEDVQVLTAYDRSTLIESAIENLKRKLIEESVVVLLIVGIFLFHVR 357 Query: 362 SALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEEW 421 SALV I+ L L I+ F VM + G+ +NIMSLGGIAIAIG MVDAA+V++EN H+ +EE Sbjct: 358 SALVIIIFLVLSILTTFAVMNHLGITSNIMSLGGIAIAIGTMVDAAIVLVENIHRRLEE- 416 Query: 422 KHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAFT 481 G W I +A +VG +FF LLI+T+SF+P+F LE Q GRLF PL T Sbjct: 417 ----------GEKLWDAIVHSAKDVGKPIFFALLIVTVSFVPLFALEGQAGRLFEPLVAT 466 Query: 482 KTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTLA 541 KT +M A+ +SV ++P+L Y IRG+IP E NPL + LI+ Y P+ ++ L Sbjct: 467 KTLSMLIASIISVIVVPVLAYYFIRGRIPGEEKNPLVKLLIKVYDPVFHISIKLRYLLLI 526 Query: 542 IAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVPE 601 + + T + +LG EF+P ++E L+YMP+ +P +S + +L DR++K PE Sbjct: 527 LFIFMGVATFYLYEKLGREFMPPLNEGTLMYMPTTVPSVSRQEMLRILNIQDRILKEFPE 586 Query: 602 VASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRP----------------------- 638 V SV GKAGRA + TDPAP+ M ET I KP+++WR Sbjct: 587 VESVLGKAGRANTPTDPAPMSMIETFITLKPQEEWRKVKVERFYSDWEIPEFIKDILRKV 646 Query: 639 -----GMTPTKLVNELDRVVKVPGLSNIWVPPIRNRLDMLATGIKSPIGVKVSGTSLADI 693 +T +L+ E+D+ + +PGLSN+W PI+ R+DM+ TGI++P+G+KV G + + Sbjct: 647 FPEERPLTYAELIREMDKAISLPGLSNMWTMPIKGRIDMITTGIQTPLGIKVYGDDVNKL 706 Query: 694 DKTAQQIEQVAKEVPGVSSALAERLSGGRYVDVDIDRLTAANYGLNIADVQSIVSSAIGG 753 ++ AQ+IE++ K+VPG+ S ER + YV++ R YGL + DV + + Sbjct: 707 NEVAQEIEKLLKDVPGIMSVFGERSANALYVEIIPKREELDRYGLTVGDVNEAILTLFAN 766 Query: 754 ENVGETIEGLARYPISVRYPRETRDSLERLRDLPILTVSGQQITLGTVAKLKISDGPPML 813 + + I G RY +++ P + R LE L + + + + L VA + + + P + Sbjct: 767 KKISTVILGRERYSVTLGIPLDYRYELETLT----IPMKDKFVPLSAVADVVVKESPSSI 822 Query: 814 KSENARPSGWIYVDVRGR-DLSSVVADLRAAVSSKVKLTPGLSIAYSGQFEYLERANARL 872 KSEN +++V D+ +V+ + +KL G +SGQFEY ++A L Sbjct: 823 KSENGLLVSYVFVTPDPEVDMGTVIERAEKVLKENLKLPKGYYYEWSGQFEYWKKALENL 882 Query: 873 KLVVPATLMIIFVLLYLTFRRFDEAALIMASLPFALVGGIWFLYAQGYNLSVATGVGFIA 932 K++VP+ +++I +L++ TF + E L++ +LP A GG+ +Y YN+S+A+ GF+A Sbjct: 883 KVIVPSVILLIILLVWFTFNKLFETFLVLITLPIATFGGVLLMYLLNYNISIASIAGFLA 942 Query: 933 LAGVSAEFGVVMLLYLKQAVSAREQQGGTISVPVLEDAIREGAVLRVRPKAMTVAVILAG 992 L G++AE G+VM++Y++ A+ E + + +AI +GAV R+RPK MT IL G Sbjct: 943 LLGIAAEMGIVMVVYIQNALKESEIRSKKDAF----EAIYKGAVKRIRPKFMTFGAILIG 998 Query: 993 LIPILWGSGAGSEVMSRIAAPMVGGMITAPLLSMFVIPAAY 1033 L+PI+ G G GSEVMSRIAAPMVGG+++ ++ + ++PA Y Sbjct: 999 LLPIMLGHGTGSEVMSRIAAPMVGGILSTIVIVLIIVPALY 1039