BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0201.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 449 e-126 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 365 e-101 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 291 2e-78 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 287 3e-77 Z5523 [GEPR] COG0477 Permeases of the major facilitator superfam... 262 1e-69 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 449 bits (1154), Expect = e-126, Method: Compositional matrix adjust. Identities = 232/410 (56%), Positives = 303/410 (73%), Gaps = 7/410 (1%) Query: 18 QRRRAIIATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMRPV 77 ++R A+ ++GN EWFDFT+Y FFA +IA + FP+ N T+LLLA+ATFGVGF RP+ Sbjct: 17 RQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFVTRPL 76 Query: 78 GGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESVGLFAPLIIVVARLLQGFSA 137 GGI+LGIYADR GR+ AL+++ LLMA+GT +I +APTY G+ AP+I V+ARLLQGFSA Sbjct: 77 GGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQGFSA 136 Query: 138 GGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTTSLDPQALASWGWR 197 GGEMG ATA+L E AP +RA+Y+SWIQAS+G+A++ GA +GT T+ LD +AL +WGWR Sbjct: 137 GGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRAWGWR 196 Query: 198 LPFLLGIIIGPVGYYIRNHLEETPTFLEE--KDKTDSPLKEVIRNFPRETSASFSMVILW 255 +PF LG++IGP+GY IR+ L+ETP F + + DSPL EV+R R S+VILW Sbjct: 197 IPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASIVILW 256 Query: 256 TVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRL--DMGLER---PA 310 TVCTYVLLFYM TY++ VLKLP + GF M G+ +M+ AP+ G L +G +R A Sbjct: 257 TVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRVLSGA 316 Query: 311 AALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLSTGLS 370 A ILVLAYP++AY+N AP+ TL+ Q+VFG L AAYTGPI AF++LFP KVLSTGLS Sbjct: 317 ALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLSTGLS 376 Query: 371 VAYNLAVTIFGGFASFFITWLIAATGNNMAPAFYVMIAAAISFVGTRFVR 420 AYNL V + GGFA F++TWL A +AP YVM+AA +S +GT ++R Sbjct: 377 TAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLR 426 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 202/414 (48%), Positives = 269/414 (64%), Gaps = 7/414 (1%) Query: 15 TNHQRRRAIIATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFM 74 + R R + A VIGN LEW+DF VY F + +IA+LFFP+G++ TSLL+A+ATFGVGFFM Sbjct: 6 SGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFM 65 Query: 75 RPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESVGLFAPLIIVVARLLQG 134 RPVGG+LLG+YADR GRKAA+ + ILLM + MI APTY ++G+ APL+IV+AR+LQG Sbjct: 66 RPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQG 125 Query: 135 FSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTTSLDPQALASW 194 F+ GGE SATAFL E AP R Y SW +AV GA +G VT LD +AL SW Sbjct: 126 FATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESW 185 Query: 195 GWRLPFLLGIIIGPVGYYIRNHLEETPTFLE--EKDKTDSPLKEVIRNFPRETSASFSMV 252 GWR+PFL G++IGPVG +IR ++ ET FLE + L V+R + R S + Sbjct: 186 GWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLT 245 Query: 253 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLDMGLERPAAA 312 ++ TV YV+L MPT++ K L LP F+ M + ++ P+ G L + R Sbjct: 246 VVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVL 305 Query: 313 LILVLA-----YPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 367 L+ LA YP+FA++ +APSL LL+ QL+ T I + GP A +E FP +V ST Sbjct: 306 LVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRST 365 Query: 368 GLSVAYNLAVTIFGGFASFFITWLIAATGNNMAPAFYVMIAAAISFVGTRFVRE 421 GL+VAYNLAV +FGGFA F +TWL G+ +APAFYV+ AA + + T ++RE Sbjct: 366 GLAVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLRE 419 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 291 bits (744), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 164/416 (39%), Positives = 235/416 (56%), Gaps = 10/416 (2%) Query: 16 NHQRRRAIIATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMR 75 N + RAI V GN LE FDF VY ++A IA FFP GN SL+L++ TFG GF MR Sbjct: 7 NESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMR 66 Query: 76 PVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESVGLFAPLIIVVARLLQGF 135 P+G I+LG Y DR GR+A L +T++LMA GT +I L P Y ++GL APL++++ RLLQGF Sbjct: 67 PLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGF 126 Query: 136 SAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTTSLDPQALASWG 195 SAGGE G + +L+E A + +Y SW S VAV+ A +G ++ L P+ + WG Sbjct: 127 SAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWG 186 Query: 196 WRLPFLLGIIIGPVGYYIRNHLEETPTFLEEKDKTDSPLKEVIRNFP---RETSASFSMV 252 WR+PFL+G +I P ++IR L ET F E+ K + E++R+ R A + Sbjct: 187 WRVPFLIGCLIVPFLFFIRRSLRETEEF--EQRKHRPTMGELLRSMGENWRLAGAGTLLA 244 Query: 253 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLDMGLERPA-- 310 ++ TV Y++ Y PT+ VL + I + G ++ P++G L + R Sbjct: 245 VMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPL 304 Query: 311 ---AALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 367 +AL L+ AYP ++ + PS LL +L L Y G ++ +E+ P ++ +T Sbjct: 305 IVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTT 364 Query: 368 GLSVAYNLAVTIFGGFASFFITWLIAATGNNMAPAFYVMIAAAISFVGTRFVREPQ 423 G S+AY+LA IFGGF T LI ATGN P ++ AA V T V +PQ Sbjct: 365 GFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQ 420 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 287 bits (735), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 164/421 (38%), Positives = 234/421 (55%), Gaps = 10/421 (2%) Query: 16 NHQRRRAIIATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMR 75 N + R+I V GN LE +DF VY ++A IA FFP N+ SL+L++ TFGVGF MR Sbjct: 7 NESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMR 66 Query: 76 PVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESVGLFAPLIIVVARLLQGF 135 P+G ++LG Y DR GR+A L +T+ LMA GT +I L P Y ++GL APL++++ RLLQGF Sbjct: 67 PLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGF 126 Query: 136 SAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTTSLDPQALASWG 195 SAG E+G + +L E + + ++ SW AS VAV+ A +G ++ L P+ + WG Sbjct: 127 SAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWG 186 Query: 196 WRLPFLLGIIIGPVGYYIRNHLEETPTFLEEKDKTDSPLKEVIRNFP---RETSASFSMV 252 WR+PFL+G +I P + IR L+ET F + K + L E+ R+ R A +V Sbjct: 187 WRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHR--PALGEIFRSMGENWRLVGAGTLLV 244 Query: 253 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRL-DMGLERPA- 310 ++ TV Y++ Y PT+ VL L I + G P++G + D RP Sbjct: 245 VMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLL 304 Query: 311 ---AALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 367 AL L+ AYP ++ + PS LL +L L +Y G ++ +E+ P V +T Sbjct: 305 ITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTT 364 Query: 368 GLSVAYNLAVTIFGGFASFFITWLIAATGNNMAPAFYVMIAAAISFVGTRFVREPQYLQQ 427 G S+AY+LA IFGGF TWLI ATGN P ++ AA V T V +P Sbjct: 365 GFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKPAGRHV 424 Query: 428 H 428 H Sbjct: 425 H 425 >Z5523 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 438 Score = 262 bits (670), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 162/427 (37%), Positives = 242/427 (56%), Gaps = 17/427 (3%) Query: 11 IPVVTNHQRRRAIIATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLT-SLLLAVATFG 69 + V RR I A+ GN LE+FDF VY+FF V I+ LFFP D +LLLA ATFG Sbjct: 9 VSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFG 68 Query: 70 VGFFMRPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESVGLFAPLIIVVA 129 V FFMRP+GGI++G +ADR GRK A+ TI LM++GT MIG+APTYE+ G + +V+A Sbjct: 69 VSFFMRPLGGIIVGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLA 128 Query: 130 RLLQGFSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTTSL--- 186 RL+QG +AGGE+G++ + L E AP R +YSSW A+ G+A G V ++ L Sbjct: 129 RLIQGVAAGGEVGASMSLLVESAPANRRGFYSSWSLATQGLATTFGGVVALGLSAWLPFA 188 Query: 187 --DPQALASWGWRLPFLLGIIIGPVGYYIRNHLEET---PTFLEEKDKTDSPLKEVIRNF 241 +A WGWR+PF +G+++ PVG ++R LE P ++ ++S ++++ Sbjct: 189 TGSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPEPAHNKKAAASESAFSLLMQH- 247 Query: 242 PRETSAS-FSMVILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVG 300 + T A+ + I TV TY+ LFY T++ K L + Q A ++ G+ V A +VG Sbjct: 248 -KATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVG 306 Query: 301 RLDMGLERPAAALI-----LVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAA 355 L + R LI L+ ++P F + + PS LL V + P++ Sbjct: 307 MLCDSVGRKKLILISRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLL 366 Query: 356 FSELFPAKVLSTGLSVAYNLAVTIFGGFASFFITWLIAATGNNMAPAFYVMIAAAISFVG 415 SEL P ++ + G ++ Y++ V IFGGFA +F T I + APA+Y+ +S + Sbjct: 367 ISELLPKRIRALGFALVYSIGVAIFGGFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLA 426 Query: 416 TRFVREP 422 +V+EP Sbjct: 427 LLYVKEP 433