BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0181.p (727 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3704_1 [NT] COG0643 Chemotaxis protein histidine kinase and re... 587 e-167 mll9511_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 566 e-161 Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 266 2e-70 CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 232 3e-60 HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and re... 230 8e-60 >PA3704_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Pae Pseudomonas aeruginosa Length = 640 Score = 587 bits (1514), Expect = e-167, Method: Compositional matrix adjust. Identities = 333/637 (52%), Positives = 437/637 (68%), Gaps = 9/637 (1%) Query: 3 TPD-LSQMSMLDLFRFEAESQIAQLNTSLLALEQQPTAAEHLEACMRAGHSLKGAARIVG 61 TPD + S+L+LFR EAE+Q LN L+ALE+ PT A+ LEACMRA HSLKGAARIVG Sbjct: 2 TPDQMRDASLLELFRLEAEAQTQVLNAGLMALERSPTQADQLEACMRAAHSLKGAARIVG 61 Query: 62 LETAVKVAHVLEDCFVLAQQGKLRLEKKHIDVLLRGADLLGRIASPPDGDETWVDHAGSA 121 L+ V+VAHV+EDC V AQ G+L L+ +HID LL+G DLL RI +PP GD W + AG Sbjct: 62 LDAGVRVAHVMEDCLVEAQDGRLLLQSEHIDALLQGCDLLLRIGTPPAGDAGWAEGAGRE 121 Query: 122 EVQAFLQALPA-VMSG---ADADPWPAPSAALQEAFAAEAAPQPPAPAPSAAAMEPPQPA 177 E+ + L V SG A A+ PA + L EA A + E P Sbjct: 122 EIDGLVLRLEGLVRSGLPLARAE-LPATTPGLPEAVPEAPPAASAAASDDND--EEPAGQ 178 Query: 178 ASAPIVNQTAAARAVRVSADSLDRLLSLTGESLVESRRLKPFSASMLRMKRVQREAVQAL 237 A + + R +RV+A+ LDRLL ++ +SLVE +R+KP + S+ R++R+Q A +AL Sbjct: 179 AGGEQAEERRS-RVLRVTAERLDRLLDISSKSLVEFQRIKPLADSLQRLRRLQSSASRAL 237 Query: 238 DLLQQKLAASQLDEFAQTTLAELRALMQTNQQLLGEQLIALDAFDRRSVNLSQQLYDEAL 297 D++++ + + LD AQ L E R L+ QQ+L + + LD F + +Q LYD AL Sbjct: 238 DVVRETVQETALDPQAQAMLGEARQLIGECQQMLVQHIADLDEFAWQGGQRAQVLYDAAL 297 Query: 298 ACRMRPFADGTAGFARMVRDVGNALGKSVRLDISGTATQIDRDILEKLEAPLGHLLRNAV 357 A RMRPFAD +G ARMVRD+G +LGK VRL + G +TQ+DRD+LEKLEAPL HLLRNAV Sbjct: 298 ASRMRPFADVLSGQARMVRDLGRSLGKQVRLLVEGESTQVDRDVLEKLEAPLTHLLRNAV 357 Query: 358 DHGIEDGSTRRAAGKPEQGVVRLEARHSAGMLLIEVADDGAGIDLDALRRTVVMRGLATQ 417 DHGIE TR AAGKP +G + + ARH AGML++E++DDG GIDL LR TV+ R AT Sbjct: 358 DHGIEAPETRLAAGKPAEGRITIRARHHAGMLVLELSDDGGGIDLQRLRETVLNRQFATA 417 Query: 418 EIAERLSDAELLDFLLLPSFSLRETVTEISGRGVGLDVVADMLKQVRGTIRITTRPGQGS 477 E +LS+ ELL FL LP FS+RE VTE+SGRGVGLD V M++Q+RG +R+ R GQG+ Sbjct: 418 ETVAQLSEEELLAFLFLPGFSMREQVTEVSGRGVGLDAVQHMVRQLRGGVRMEQRQGQGA 477 Query: 478 RFLLQLPLTLSVIRSLLVEIAGEPYAFPLAYVNRTLRLPAEALQTLEGYQHFSHGGRQVG 537 F +++PLTLSV+RSL+VEI E YAFPLA++ R L AE + LEG QHF + GR VG Sbjct: 478 LFHVEVPLTLSVVRSLVVEIGEEAYAFPLAHIERMCELEAEEIVQLEGRQHFWYEGRHVG 537 Query: 538 LVSAHQVLQRGQWRVRDGSVCVVVIGEEEHSYGIAVDAFLGERMLVVQPLDARLGKIPDI 597 LVSA Q+LQR + +G++ VVV+ + + YG+AV+ F+GER LVV PLD RLGK+ D+ Sbjct: 538 LVSAAQLLQRPESSRTEGAIPVVVVRDRDAVYGVAVERFVGERTLVVMPLDPRLGKVRDV 597 Query: 598 LAGALMEDGAPLLILDVADLLRTVEKLTASGRLQTVD 634 AGAL++DG+P+LILDV DLL +V KL +SGRL+ +D Sbjct: 598 SAGALLDDGSPVLILDVEDLLHSVGKLLSSGRLERID 634 >mll9511_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Mlo Mesorhizobium loti Length = 630 Score = 567 bits (1460), Expect = e-161, Method: Compositional matrix adjust. Identities = 325/629 (51%), Positives = 422/629 (67%), Gaps = 16/629 (2%) Query: 1 MSTPDLSQMSMLDLFRFEAESQIAQLNTSLLALEQQPTAAEHLEACMRAGHSLKGAARIV 60 M+ D SQ+SML LF+ E E+Q L + LLALE+ P AA+ LEACMRA HSLKGAARI+ Sbjct: 1 MTDEDFSQVSMLSLFQAELETQSQALTSGLLALERDPIAADALEACMRAAHSLKGAARII 60 Query: 61 GLETAVKVAHVLEDCFVLAQQGKLRLEKKHIDVLLRGADLLGRIASPPDGDETWVDHAGS 120 L AVKVA+ +EDC V AQ+G LR+ ++HID LL+G+DLL IAS + + Sbjct: 61 DLMPAVKVANAMEDCLVAAQRGHLRVRREHIDTLLQGSDLLKLIAS------GSSSESAN 114 Query: 121 AEVQAFLQALPAVMSGADADPWPAPSAALQEAFAA-EAAPQPPAPAPSAAAMEPPQPAAS 179 +EV+ FL + +A P P SAA FA + A + PA SA + P A Sbjct: 115 SEVETFLAKFEELFL-PEAKPRPQDSAA---DFATPDHAQEQPATTSSATLLVGTVPQAH 170 Query: 180 APIVNQTAAARAVRVSADSLDRLLSLTGESLVESRRLKPFSASMLRMKRVQREAVQALDL 239 I + R VRV+ADSL+RLL L GESL+E+RRL+PF+ +LR+KR+Q + A D Sbjct: 171 GNI----GSDRMVRVTADSLNRLLGLAGESLIEARRLRPFADGLLRLKRLQSDLASAFDN 226 Query: 240 LQQKLAASQLDEFAQTTLAELRALMQTNQQLLGEQLIALDAFDRRSVNLSQQLYDEALAC 299 L L D LAE + ++ +Q L E+L LD+ DR++ +L+ +LYDE LA Sbjct: 227 LHAVLPPGSNDAAVVEALAEAQRKLRLSQAFLAERLDELDSVDRKATDLANRLYDETLAS 286 Query: 300 RMRPFADGTAGFARMVRDVGNALGKSVRLDISGTATQIDRDILEKLEAPLGHLLRNAVDH 359 RMRPF DG +AR VRD+G LGK VRL+I G +T IDRDILE+L+APLGHLLRNAVDH Sbjct: 287 RMRPFEDGVRHYARTVRDLGRTLGKRVRLEIVGGSTGIDRDILEQLDAPLGHLLRNAVDH 346 Query: 360 GIEDGSTRRAAGKPEQGVVRLEARHSAGMLLIEVADDGAGIDLDALRRTVVMRGLATQEI 419 G+E R A GKPE+G++RLEARH+AG+L I V DDG GI+L LR TVV R LAT+E Sbjct: 347 GLEPPEERLAMGKPEEGLIRLEARHNAGLLQIAVVDDGRGIELSTLRETVVARQLATRES 406 Query: 420 AERLSDAELLDFLLLPSFSLRETVTEISGRGVGLDVVADMLKQVRGTIRITTRPGQGSRF 479 A+ LS+ ELL FL LP FS++ +T++SGRGVGLD V M K+VRG +++ G G+RF Sbjct: 407 ADTLSETELLAFLFLPGFSMKAGLTDVSGRGVGLDAVQAMTKEVRGVASVSSEFGHGTRF 466 Query: 480 LLQLPLTLSVIRSLLVEIAGEPYAFPLAYVNRTLRLPAEALQTLEGYQHFSHGGRQVGLV 539 LQLPLTLSV+R+LLV++ GEPYAFPLA + +TL+L + L+G HF RQ+GLV Sbjct: 467 QLQLPLTLSVLRTLLVDVDGEPYAFPLAAIAKTLKLQRTQINLLQGRPHFRLNDRQIGLV 526 Query: 540 SAHQVLQRGQWRVRDGSVCVVVI-GEEEHSYGIAVDAFLGERMLVVQPLDARLGKIPDIL 598 +A +VL RG+ + VVV+ +YG+ VD FLGER LV++PLD R KI DI Sbjct: 527 TAREVLDRGEPGSEPDELSVVVVDAGRGDAYGLIVDRFLGERELVIRPLDPRFAKIKDIS 586 Query: 599 AGALMEDGAPLLILDVADLLRTVEKLTAS 627 A ALMEDG+P+LI DV DL+R+VEKL +S Sbjct: 587 AAALMEDGSPVLIFDVDDLIRSVEKLASS 615 >Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Cje Campylobacter jejuni Length = 622 Score = 266 bits (679), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 179/659 (27%), Positives = 307/659 (46%), Gaps = 97/659 (14%) Query: 11 MLDLFRFEAESQIAQLNTSLLALEQQPTAAEHLEACMRAGHSLKGAARIVGLETAVKVAH 70 +L+ F EA + Q++ L+ LE P E L R H++KG++ + + K+ H Sbjct: 7 ILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDVLTKLTH 66 Query: 71 VLEDCFVLAQQGKLRLEKKHIDVLLRGADLLGRIASP--PDGDETWVDHAGSAEVQAFLQ 128 +ED A+ G+L++ +DV+L D + + + +G++T + +++ Sbjct: 67 HMEDVLNKARHGELKITPDIMDVVLESIDRMKTLLNSIRDNGNDTAI----GMDIEPICA 122 Query: 129 ALPAVMSG------ADADPWPAPSAALQEAFAAEAAPQPP-------------------- 162 L A+ G D++ P A L+ A P+P Sbjct: 123 RLTAISEGESPVVATDSNEKSIPQAELEAPKQEIATPEPEVDVNQLSDSEVEAEIERLLK 182 Query: 163 -------------------APAPSAAAMEPPQPAASAPI----VNQTAAARAVRVSADSL 199 AP P+ P + + N ++ + +RV L Sbjct: 183 VRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVKRL 242 Query: 200 DRLLSLTGESLVESRRLKPFSASMLRMKRVQREAVQALDLLQQKLAASQLDEFAQTTLAE 259 D L++L GE ++ RL ++ D ++++ + E +++ Sbjct: 243 DHLMNLIGELVLGKNRL-----------------LKIYDDVEERYEGEKFLEELNQVVSQ 285 Query: 260 LRALMQTNQQLLGEQLIALDAFDRRSVNLSQQLYDEALACRMRPFADGTAGFARMVRDVG 319 L +++ T+ QL + RM+P A F R+VRD+ Sbjct: 286 L-SIIITDVQLA------------------------VMKTRMQPIAKVFNKFPRVVRDLS 320 Query: 320 NALGKSVRLDISGTATQIDRDILEKLEAPLGHLLRNAVDHGIEDGSTRRAAGKPEQGVVR 379 LGK + L+I+G T++D+ I+E++ P+ H++RN+ DHG+ED +TR A GKPE+G+V+ Sbjct: 321 RELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDPATRAANGKPEKGIVQ 380 Query: 380 LEARHSAGMLLIEVADDGAGIDLDALRRTVVMRGLATQEIAERLSDAELLDFLLLPSFSL 439 L+A + +++E+ DDG G+D + L+ + + L T+ A++++D E + P FS Sbjct: 381 LKAYNEGNHIVVEITDDGKGLDPNGLKAKAIEKNLITEREADQMTDKEAFALIFKPGFST 440 Query: 440 RETVTEISGRGVGLDVVADMLKQVRGTIRITTRPGQGSRFLLQLPLTLSVIRSLLVEIAG 499 VT +SGRGVG+DVV ++++ G I I + G+GS F L++PLTL++I+SLLV Sbjct: 441 AAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSFKLKIPLTLAIIQSLLVGTQE 500 Query: 500 EPYAFPLAYVNRTLRLPAEALQTLEGYQHFSHGGRQVGLVSAHQVLQRGQWRVRDGSVCV 559 E YA PLA V T+R+P + + T+EG + LV V Q V Sbjct: 501 EFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLVRLSDVFGVKQVLESGDQTYV 560 Query: 560 VVIGEEEHSYGIAVDAFLGERMLVVQPLDARLGKIPDILAGALMEDGAPLLILDVADLL 618 VVIG E GI VD +G+ +V++ + L I I + DG LI+DV ++ Sbjct: 561 VVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAGATIRGDGRVTLIIDVGAMM 619 >CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Ccr Caulobacter vibrioides Length = 764 Score = 232 bits (591), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 182/634 (28%), Positives = 301/634 (47%), Gaps = 90/634 (14%) Query: 15 FRFEAESQIAQLNTSLLALEQQPTAAEHLEACMRAGHSLKGAARIVGLETAVKVAHVLED 74 F EA + ++ L+ E +P L+ R H+LKGA +GL +AH E Sbjct: 8 FLVEAHEGLEVIDVELVRFEARPEDRAALDKIFRLVHTLKGACGFLGLGRLEAIAHAGET 67 Query: 75 CFVLAQQGKLRLEKKHIDVLLRGADL-------LGRIASPPDGDETWVDHAGSAEVQAFL 127 + G+L + + + +L D LG + P+GD+T + A ++AF Sbjct: 68 LLGRFRDGRLEVSSQAVTAVLSAIDRIKMILDGLGDLGREPEGDDTALIQA----LEAFS 123 Query: 128 Q-ALPAVMSGADADPWP------APSAAL----------QEAF-AAEA----APQPPAPA 165 A P+ S A+P P AP L + AF AAE AP PP Sbjct: 124 DGAAPSEQSPVAAEPEPLAADVAAPERTLRPGEVSLEELEAAFLAAEGPVFDAPAPPVET 183 Query: 166 PSAAA----MEPPQPAASAP--IVNQTAAARAVRVSADSLDRLLSLTGESLVESRRLKPF 219 PSAA+ EP Q SAP +V+++ + +RV D L+ +++L E LV +R Sbjct: 184 PSAASPAATFEPDQ-TDSAPEALVSESLGPQTIRVGVDVLEDMMTLVSE-LVLTRN---- 237 Query: 220 SASMLRMKRVQREAVQALDLLQQKLAASQLDEFAQTTLAELRALMQTNQQLLGEQLIALD 279 +L++ R + DE L Sbjct: 238 --QLLQLNR------------------GRGDETFTPPL---------------------- 255 Query: 280 AFDRRSVNLSQQLYDEALACRMRPFADGTAGFARMVRDVGNALGKSVRLDISGTATQIDR 339 +R +++ +L D + RM+P R+VRD+ LGK + L + G AT++DR Sbjct: 256 ---QRLSSITGELQDSVMKTRMQPIGQAWKKLPRLVRDLSGELGKPIELVMEGEATELDR 312 Query: 340 DILEKLEAPLGHLLRNAVDHGIEDGSTRRAAGKPEQGVVRLEARHSAGMLLIEVADDGAG 399 +LE++ PL H++RN+ DHG+E RRAAGKPE G++ L A H G ++I + DDG G Sbjct: 313 QVLEQIRDPLTHMVRNSADHGLEGPEARRAAGKPEAGLIHLSAYHEGGAIVIRLRDDGRG 372 Query: 400 IDLDALRRTVVMRGLATQEIAERLSDAELLDFLLLPSFSLRETVTEISGRGVGLDVVADM 459 +D +R + +G+ + AE +++A++ + P FS VT +SGRGVG+DVV Sbjct: 373 LDTARIREKAIEKGIVGRAEAETMTEAQVHRLIFAPGFSTAAVVTNVSGRGVGMDVVRSN 432 Query: 460 LKQVRGTIRITTRPGQGSRFLLQLPLTLSVIRSLLVEIAGEPYAFPLAYVNRTLRLPAEA 519 ++Q+ G I + + GQG +++PLTL+++ +L++ AGE +A P A V +++ A++ Sbjct: 433 IEQIGGQIELQSTLGQGCVVTVKIPLTLAIVSALIIRAAGERFAVPQASVQELVKVSADS 492 Query: 520 LQTLEGYQHFSHGGRQVGLVSAHQVLQRGQWRVRDGSVCVVVIGEEEHSYGIAVDAFLGE 579 E +H + L+ + + R + V+++ H +G+ V+ + Sbjct: 493 DHRFEEIEHVRMLRLREQLIPLIDLSEELGRERRHEAKFVLIMRVGAHRFGVLVEEVIDT 552 Query: 580 RMLVVQPLDARLGKIPDILAGALMEDGAPLLILD 613 +VV+PL + L IP L+ DG+ +LI+D Sbjct: 553 EEIVVKPLASVLRTIPVFSGATLLGDGSVVLIID 586 >HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Hpy Helicobacter pylori 26695 Length = 651 Score = 230 bits (587), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 177/646 (27%), Positives = 304/646 (47%), Gaps = 42/646 (6%) Query: 11 MLDLFRFEAESQIAQLNTSLLALEQQPTAAEHLEACMRAGHSLKGAARIVGLETAVKVAH 70 +++ F EA QL+ L+ LE P + L R H++KG++ + L + H Sbjct: 7 IMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTH 66 Query: 71 VLEDCFVLAQQGKLRLEKKHIDVLLRGADLLGRIASPPDGDETWVDHAGSAEVQAFLQAL 130 +ED A++G++++ +DV+LR DL+ + + ++ E++ ++ L Sbjct: 67 NMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQL 126 Query: 131 PAVMS----GADADPWPAPSAALQEAFAAEAAPQPPAPA---PSAAAMEPPQPAASAPIV 183 A+ S A AP +E EA + P+A P A P + Sbjct: 127 QAITSQNLESAKERTTEAPQKENKEETKEEAKEENKENKAKAPTAENTSSDNPLADEPDL 186 Query: 184 NQTAAARAVRVSADSLDRLLSLTGESLVESRRLKPFSASMLRMKRVQREAVQALDLLQQK 243 + A A V A+ ++RLL+ E+ E R K A + +E +A + Sbjct: 187 DY-ANMSAEEVEAE-IERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKTETKA 244 Query: 244 LAASQLDE-------FAQTTLAELRALMQTNQQLLGEQLIALDAFDRRSVNLSQQLYD-- 294 A + +E QT ++R L L+GE ++ + R ++ ++ YD Sbjct: 245 KAKADTEENKAPSIGVEQTVRVDVRRLDHL-MNLIGELVLGKNRLIRIYSDVEER-YDGE 302 Query: 295 ----------------------EALACRMRPFADGTAGFARMVRDVGNALGKSVRLDISG 332 + RM+P F RMVRD+ LGKS+ L I G Sbjct: 303 KFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEG 362 Query: 333 TATQIDRDILEKLEAPLGHLLRNAVDHGIEDGSTRRAAGKPEQGVVRLEARHSAGMLLIE 392 T++D+ I+E++ PL H++RN+ DHGIE RR KPE G V+L A + ++I+ Sbjct: 363 EETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKLNKPETGKVQLSAYNEGNHIVIK 422 Query: 393 VADDGAGIDLDALRRTVVMRGLATQEIAERLSDAELLDFLLLPSFSLRETVTEISGRGVG 452 ++DDG G+D L+ + +G+ ++ AE +SD E + + P FS + V+ +SGRGVG Sbjct: 423 ISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGVG 482 Query: 453 LDVVADMLKQVRGTIRITTRPGQGSRFLLQLPLTLSVIRSLLVEIAGEPYAFPLAYVNRT 512 +DVV ++++ G I I + G G+ L++PLTL++I++LLV + E YA PL+ V T Sbjct: 483 MDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLET 542 Query: 513 LRLPAEALQTLEGYQHFSHGGRQVGLVSAHQVLQRGQWRVRDGSVCVVVIGEEEHSYGIA 572 +R+ + + T++G + LV + + + V VV+IG + G+ Sbjct: 543 VRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVI 602 Query: 573 VDAFLGERMLVVQPLDARLGKIPDILAGALMEDGAPLLILDVADLL 618 VD +G+ +V++ L L I + DG LI+DV ++ Sbjct: 603 VDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMM 648