BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0081.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA311 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 226 5e-59 SMa1838 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 222 7e-58 BMEI1939 [HE] COG0111 Phosphoglycerate dehydrogenase and related... 213 3e-55 mll5489 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 208 2e-53 AGl2846 [HE] COG0111 Phosphoglycerate dehydrogenase and related ... 206 6e-53 >AGpA311 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 308 Score = 226 bits (576), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 125/291 (42%), Positives = 170/291 (58%), Gaps = 3/291 (1%) Query: 25 ARRMPELQVRLWPDLPDPDDVEAVAGWYPPAGVIERLPNLRLISSIAAGVDHV-LGAARA 83 A R PE+ PD PD V +A W+PPAG+++R NL ++ S+ AGVD LG Sbjct: 20 AERAPEIPFEYRPDAIAPDAVRFLAVWHPPAGMLQRYSNLEVLFSLGAGVDQFDLGDIPQ 79 Query: 84 HPLVPVCRIVDPALAAGMAEYVLWAVLYYHRALDQALQQQVQRVWKIPSQKPAYQTHVGL 143 +P+ R+++P +A GMAEYV +V+ HR + QQ VWK+ P+ + VG Sbjct: 80 D--LPLVRMIEPGIAEGMAEYVSLSVMLLHRHFLDYVGQQRAEVWKLKRFHPSSRLRVGF 137 Query: 144 MGLGALGSHLAGVLRDQGFTVSGWSRSAHHIEGVRTYAGDDALHAFLQAPDIVVCLLPLT 203 +G G L L GFT+S WSRS IEGV Y G+D L+AFL DI+VCLLPLT Sbjct: 138 LGAGMLAQAAIARLWPFGFTLSAWSRSEKTIEGVTCYHGEDGLNAFLPQCDILVCLLPLT 197 Query: 204 DATRKLLGRDVFAAMKPGAALVHCGRGEHLVEEDLLEALDRQHLRGAVLDVFAQEPLPAS 263 TR +L +F+ + GAAL++CGRG+HLV DLL AL L A+LDV EPL Sbjct: 198 PETRGMLNDALFSKLPKGAALINCGRGQHLVHNDLLAALATGQLSRAILDVTEPEPLEPG 257 Query: 264 NALWSHPRVVVTPHMASSAQPGVIVGQILDNLQRLRRGEAALHEVDRSRGY 314 + W + ++ +TPH AS QP V I+DN++R R G+ + VDR+ Y Sbjct: 258 HPFWRNEKIFLTPHTASMTQPDTAVDAIIDNIRRHRAGKTMVGLVDRNSLY 308 >SMa1838 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Sme Sinorhizobium meliloti Length = 326 Score = 222 bits (566), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 126/297 (42%), Positives = 176/297 (59%), Gaps = 2/297 (0%) Query: 18 AVFREEAARRMPELQVRLWPDLPDPDDVEAVAGWYPPAGVIERLPNLRLISSIAAGVDHV 77 A+F E AR +P++ + P DPD V + W P + R +L ++ SI AGVD Sbjct: 32 AIFAETFARELPDIPFAVDPAAVDPDAVRYLITWTVPDN-LARYRSLEILFSIGAGVDQF 90 Query: 78 LGAARAHPLVPVCRIVDPALAAGMAEYVLWAVLYYHRALDQALQQQVQRVWKIPSQKPAY 137 A P V V R+V+ + M EYV AVL +HR L L+QQ W+ + A Sbjct: 91 RIDA-VPPHVRVVRMVEDGIVRMMQEYVTLAVLAHHRNLPAYLEQQQGENWQAIAPVQAV 149 Query: 138 QTHVGLMGLGALGSHLAGVLRDQGFTVSGWSRSAHHIEGVRTYAGDDALHAFLQAPDIVV 197 + VG++GLG LG+ + L+ GF +SGWSRS H IEGVR +G + L L + DI+V Sbjct: 150 ERRVGVLGLGMLGTAVLDRLKPFGFPLSGWSRSPHEIEGVRCLSGRNGLDTLLGSTDILV 209 Query: 198 CLLPLTDATRKLLGRDVFAAMKPGAALVHCGRGEHLVEEDLLEALDRQHLRGAVLDVFAQ 257 CLLPLTD TR L +FA + GAALVH GRG L + L+E LD+ HL GA++DV Sbjct: 210 CLLPLTDETRGFLNAQLFARLPAGAALVHVGRGPQLDHDALVEGLDKGHLSGAMVDVTDP 269 Query: 258 EPLPASNALWSHPRVVVTPHMASSAQPGVIVGQILDNLQRLRRGEAALHEVDRSRGY 314 EPLP+ + W+HP++++TPH+AS QP +++N++R R+G + VDR RGY Sbjct: 270 EPLPSGHRFWTHPKILLTPHIASVTQPETAARAVIENIKRHRQGLEPIGLVDRRRGY 326 >BMEI1939 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Bme Brucella melitensis Length = 318 Score = 213 bits (543), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 124/302 (41%), Positives = 168/302 (55%), Gaps = 12/302 (3%) Query: 19 VFREEAARRMPELQVRLWPDLPDPDDVEAVAGWYPPAGVIERLPNLRLISSIAAGVDHVL 78 F+E A+ R +V DP +E W G + LPNL++I S+ AGVDHV Sbjct: 23 TFKESASNR----KVVTERAENDPS-IEYALVWKQKPGSLANLPNLKVIFSLGAGVDHVF 77 Query: 79 GAARAHPLVPVCRIVDPALAAGMAEYVLWAVLYYHRALDQALQQQVQRVWKIPSQKPA-Y 137 + P VP+ RI+ L M EYV+W VL +HR + +QQ VW ++PA + Sbjct: 78 RDPQV-PDVPLVRIISDDLTMRMTEYVVWQVLDHHRLGSRYRKQQQNHVWHEDRRQPAAH 136 Query: 138 QTHVGLMGLGALGSHLAGVLRDQGFTVSGWSRSAHHIEGVRTYAGDDALHAFLQAPDIVV 197 + VG+MGLG LG A L+ GF ++GWSR I+GV+TY G D FL+ DI V Sbjct: 137 EVTVGIMGLGVLGRDAAEKLKILGFNITGWSRRPQKIDGVKTYHGGDGFTEFLKTADIFV 196 Query: 198 CLLPLTDATRKLLGRDVFAAMKPGA-----ALVHCGRGEHLVEEDLLEALDRQHLRGAVL 252 CLLPLT T+ +L +FA +K L++ GRG E D+L ALDR L L Sbjct: 197 CLLPLTPDTKVILSMSMFAQLKSDGPLGEPVLINAGRGSLQNEPDILAALDRGLLSAVTL 256 Query: 253 DVFAQEPLPASNALWSHPRVVVTPHMASSAQPGVIVGQILDNLQRLRRGEAALHEVDRSR 312 DVF QEPLPA++ LW HP+V +TPH+A+ + V+V QI+ ++ R H VDRS Sbjct: 257 DVFNQEPLPANSPLWDHPKVTITPHVAAISSATVLVPQIIRQIEAFERDGTLEHVVDRST 316 Query: 313 GY 314 Y Sbjct: 317 QY 318 >mll5489 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Mlo Mesorhizobium loti Length = 313 Score = 208 bits (529), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 122/291 (41%), Positives = 167/291 (57%), Gaps = 8/291 (2%) Query: 30 ELQVRLWPD-LPDPDDVEAVAGWYPPAGVIERLPNLRLISSIAAGVDHVLGAARAHPLVP 88 E +V L PD DP AV W ++ LPNLR I SI AGVDH+ A P VP Sbjct: 25 EREVVLEPDGAKDPSITYAVV-WKQKPNLLSSLPNLRAIFSIGAGVDHIF-ADPGLPDVP 82 Query: 89 VCRIVDPALAAGMAEYVLWAVLYYHRALDQALQQQVQRVWKIPSQKPAYQTHVGLMGLGA 148 + ++V L M EYV+W VL +HR QQQ +++W P Q+PA VG+MGLG Sbjct: 83 IVKVVADNLTQYMTEYVVWRVLDHHRQGLLYRQQQQKKIWHEPPQRPAGDISVGIMGLGN 142 Query: 149 LGSHLAGVLRDQGFTVSGWSRSAHHIEGVRTYAGDDALHAFLQAPDIVVCLLPLTDATRK 208 LG A VL GF V+GWSR+ ++GV TY+G+ L FL+A DI+V LLPLT T+ Sbjct: 143 LGRAAASVLLSLGFAVNGWSRTERPMQGVATYSGEAGLIPFLKATDILVVLLPLTPDTQG 202 Query: 209 LLGRDVFAAMKP-----GAALVHCGRGEHLVEEDLLEALDRQHLRGAVLDVFAQEPLPAS 263 ++ V ++ G+ L++ GRG + D++ ALD L+ A LDVF EPLP + Sbjct: 203 IINYGVLKELRKRNGLGGSVLINAGRGRLQKDADIVRALDDGTLKEASLDVFEVEPLPKT 262 Query: 264 NALWSHPRVVVTPHMASSAQPGVIVGQILDNLQRLRRGEAALHEVDRSRGY 314 + LW+HP+V VTPH A+++ P + +L + RGE + VDR GY Sbjct: 263 SPLWNHPKVFVTPHAAATSDPMHLAPTMLRQMDAFERGEKLENLVDRKAGY 313 >AGl2846 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 349 Score = 206 bits (524), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 123/296 (41%), Positives = 165/296 (55%), Gaps = 2/296 (0%) Query: 19 VFREEAARRMPELQVRLWPDLPDPDDVEAVAGWYPPAGVIERLPNLRLISSIAAGVDHVL 78 +FR+ AR +P+L + +PD V + W P I R NL ++ SI AGVD Sbjct: 56 IFRQALARDLPDLPFSMDAASVNPDAVRYLISWTVPED-IGRYRNLEILFSIGAGVDQFH 114 Query: 79 GAARAHPLVPVCRIVDPALAAGMAEYVLWAVLYYHRALDQALQQQVQRVWKIPSQKPAYQ 138 A P V V R+VD + M EYV VL HR L L QQ Q +WK Q+ A + Sbjct: 115 IDA-VPPHVKVVRMVDEGITRMMQEYVSLGVLALHRNLPAYLGQQRQGLWKAVPQRQAEE 173 Query: 139 THVGLMGLGALGSHLAGVLRDQGFTVSGWSRSAHHIEGVRTYAGDDALHAFLQAPDIVVC 198 VG++GLG LG L+ GF +SGWSRS I+GV + G+ L L DI+VC Sbjct: 174 CRVGVLGLGMLGVAALERLKPFGFPLSGWSRSPREIDGVTCHHGEAGLAKTLTTSDILVC 233 Query: 199 LLPLTDATRKLLGRDVFAAMKPGAALVHCGRGEHLVEEDLLEALDRQHLRGAVLDVFAQE 258 LLPLT+ T LL + + GA LVH GRG L + L++ALD L GAVLDV E Sbjct: 234 LLPLTEETTGLLNSERLGMLPEGAGLVHAGRGRQLDHDALIDALDSGRLSGAVLDVTEPE 293 Query: 259 PLPASNALWSHPRVVVTPHMASSAQPGVIVGQILDNLQRLRRGEAALHEVDRSRGY 314 PLP + W+HP++++TPH+AS QP +++N++R + G L VDR+RGY Sbjct: 294 PLPEDHRFWAHPKILLTPHVASVTQPHSAARTVVENIKRYQSGLEPLGLVDRNRGY 349