BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0161.p (273 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll7191 [IQR] COG1028 Dehydrogenases with different specificitie... 226 4e-59 SMc00880 [IQR] COG1028 Dehydrogenases with different specificiti... 224 1e-58 mlr4741 [IQR] COG1028 Dehydrogenases with different specificitie... 190 2e-48 CC0821 [IQR] COG1028 Dehydrogenases with different specificities... 187 2e-47 AGc1273 [IQR] COG1028 Dehydrogenases with different specificitie... 181 1e-45 >mll7191 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 226 bits (576), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 119/254 (46%), Positives = 156/254 (61%), Gaps = 5/254 (1%) Query: 12 ASYPWLAGQVVFISGGASGIGEALVKAFWEQGARVAFCDIDPAAGQALCQRLAAQPGSAP 71 A YP L G+ VFI+GG SGIGE+LV+ F QG+RVAF D+ + L + +AA+ AP Sbjct: 8 AIYPSLKGRSVFITGGGSGIGESLVRHFCAQGSRVAFVDLSEEPSRHLVEAIAAEGHPAP 67 Query: 72 ARHTPWFAVCDVRDIPAYQVVLDHAAAALGAIRVLVNNAGRDTRHGLDELSVEMWNDMLS 131 F CD+RD+ Q A G I+VL NNAG D RH +++V W+D ++ Sbjct: 68 L-----FIPCDLRDVEQLQAATAQAMQHNGPIQVLCNNAGNDDRHQTKDVTVAYWDDRMA 122 Query: 132 VNLSHHVFATQRVAPGMREAGGGAIINLGSISWLRGRPNLIGYTASKAAISGITRTLARE 191 VNL H FA Q V P M GGG+IIN GSI+W+ G P+ Y +KAA+ G+TR LARE Sbjct: 123 VNLRHQFFAAQAVRPQMSAQGGGSIINFGSITWMVGDPDCPAYVTAKAAVYGMTRALARE 182 Query: 192 LGEAGIRVNAVLPGAVVTERQTALWRDASSDRQFLDLQCLKFRVEPTHIADSVLFLASPQ 251 LG IRVN ++PG V+TERQ LW + + +RQ + QCL R++P IA LFLA+ Sbjct: 183 LGPERIRVNCMVPGWVMTERQMRLWLNPAGERQIAERQCLPDRLQPADIARMALFLAADD 242 Query: 252 AAAVTGQNLIVDAG 265 + T Q IVDAG Sbjct: 243 SRMCTSQQFIVDAG 256 >SMc00880 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 256 Score = 224 bits (572), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 119/258 (46%), Positives = 163/258 (63%), Gaps = 5/258 (1%) Query: 9 LPRASYPWLAGQVVFISGGASGIGEALVKAFWEQGARVAFCDIDPAAGQALCQRLAAQPG 68 LP + +P L + V ++GG SGIG ALV+AF QGARVAF DI + ALC+++AAQ G Sbjct: 3 LPSSQFPDLRDRGVLVTGGGSGIGAALVEAFARQGARVAFVDIAAESSLALCEKVAAQTG 62 Query: 69 SAPARHTPWFAVCDVRDIPAYQVVLDHAAAALGAIRVLVNNAGRDTRHGLDELSVEMWND 128 AP F D+R++ A + D A A LG++RVLVNNA RD R L+ ++ E W++ Sbjct: 63 QAP-----HFIQADLRNVEAVRAAADEAVAKLGSVRVLVNNAARDDRQALEAVTEESWDE 117 Query: 129 MLSVNLSHHVFATQRVAPGMREAGGGAIINLGSISWLRGRPNLIGYTASKAAISGITRTL 188 LSVNL H F Q VAP M+ GGG+I+N SI++L P + Y+ +KA I G+T++L Sbjct: 118 SLSVNLRHLFFMCQAVAPHMQRQGGGSIVNFSSIAFLLNMPEIPAYSTAKAGIIGLTKSL 177 Query: 189 ARELGEAGIRVNAVLPGAVVTERQTALWRDASSDRQFLDLQCLKFRVEPTHIADSVLFLA 248 A +LG IRVNA+LPG +VTERQ LW S + + QCLK + + LFLA Sbjct: 178 AGKLGPDNIRVNAILPGMIVTERQRRLWLTEESIARMQERQCLKRMLVADDLVGPCLFLA 237 Query: 249 SPQAAAVTGQNLIVDAGL 266 S +AA+T Q +I+D G+ Sbjct: 238 SDSSAAMTAQAMIIDGGV 255 >mlr4741 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 254 Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 111/258 (43%), Positives = 149/258 (57%), Gaps = 5/258 (1%) Query: 9 LPRASYPWLAGQVVFISGGASGIGEALVKAFWEQGARVAFCDIDPAAGQALCQRLAAQPG 68 +P A + L G V I+GG SGIG AL + F QGA VAF DI L R+ + G Sbjct: 1 MPSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFG 60 Query: 69 SAPARHTPWFAVCDVRDIPAYQVVLDHAAAALGAIRVLVNNAGRDTRHGLDELSVEMWND 128 P + D+RDI A + AA A G + VL+NNA D RH +++++VE W++ Sbjct: 61 -----RRPLYLKTDLRDIEALRASAARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDN 115 Query: 129 MLSVNLSHHVFATQRVAPGMREAGGGAIINLGSISWLRGRPNLIGYTASKAAISGITRTL 188 ++NL H F Q VAPGM+ AGGG+IIN S S+L P++ YTA+KA I G+T+ L Sbjct: 116 NQAINLRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAYTAAKAGILGLTKGL 175 Query: 189 ARELGEAGIRVNAVLPGAVVTERQTALWRDASSDRQFLDLQCLKFRVEPTHIADSVLFLA 248 A +LG IRVNAV PG V+TERQ W + + QC+K + P + +VLFLA Sbjct: 176 AGKLGPDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLA 235 Query: 249 SPQAAAVTGQNLIVDAGL 266 S + +T Q LIVD G Sbjct: 236 SDASRMLTAQMLIVDGGF 253 >CC0821 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 248 Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 115/257 (44%), Positives = 150/257 (58%), Gaps = 11/257 (4%) Query: 9 LPRASYPWLAGQVVFISGGASGIGEALVKAFWEQGARVAFCDIDPAAGQALCQRLAAQPG 68 + A YP L G+ V I+GG SGIG L F QGA V F DI +AL LA P Sbjct: 1 MSSAIYPSLKGKRVVITGGGSGIGAGLTAGFARQGAEVIFLDIADEDSRALEAELAGSP- 59 Query: 69 SAPARHTPWFAVCDVRDIPAYQVVLDHAAAALGAIRVLVNNAGRDTRHGLDELSVEMWND 128 P + CD+ ++ A + V A +G + VLVNNAG D RH L +++ W++ Sbjct: 60 -----IPPVYKRCDLMNLEAIKAVF----AEIGDVDVLVNNAGNDDRHKLADVTGAYWDE 110 Query: 129 MLSVNLSHHVFATQRVAPGMREAGGGAIINLGSISWLRGRPNLIGYTASKAAISGITRTL 188 ++VNL H +F TQ VAPGM++ GGGA+IN GSISW G +L+ Y +KA I G+TR L Sbjct: 111 RINVNLRHMLFCTQAVAPGMKKRGGGAVINFGSISWHLGLEDLVLYETAKAGIEGMTRAL 170 Query: 189 ARELGEAGIRVNAVLPGAVVTERQTALWRDASSDRQFLDLQCLKFRVEPTHIADSVLFLA 248 ARELG IRV V+PG V T+RQ W + Q + QCLK R+ P ++A VLFLA Sbjct: 171 ARELGPDDIRVTCVVPGNVKTKRQEK-WYTPEGEAQIVAAQCLKGRIVPENVAALVLFLA 229 Query: 249 SPQAAAVTGQNLIVDAG 265 S A+ TG +DAG Sbjct: 230 SDDASLCTGHEYWIDAG 246 >AGc1273 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 260 Score = 181 bits (460), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 109/260 (41%), Positives = 150/260 (57%), Gaps = 5/260 (1%) Query: 7 TPLPRASYPWLAGQVVFISGGASGIGEALVKAFWEQGARVAFCDIDPAAGQALCQRLAAQ 66 TP+ +A +P L V ++GG SGIG +LV+AF QGA+V+F DI AL +RLAA Sbjct: 5 TPMMQAQFPDLKDAGVLVTGGGSGIGASLVEAFAMQGAKVSFIDIAEQPSIALVERLAA- 63 Query: 67 PGSAPARHTPWFAVCDVRDIPAYQVVLDHAAAALGAIRVLVNNAGRDTRHGLDELSVEMW 126 + P H + D+ DI A + +D AA+A G I+VLVNNA D RH +D ++ W Sbjct: 64 --TVP--HPVHYFRADLSDIDAIKRTVDMAASATGGIKVLVNNAAWDDRHDIDSVTEAYW 119 Query: 127 NDMLSVNLSHHVFATQRVAPGMREAGGGAIINLGSISWLRGRPNLIGYTASKAAISGITR 186 + +VNL F Q P +R+A +I+N SIS+L L Y A+KA I G+T+ Sbjct: 120 DANQAVNLKQMFFTVQAALPHLRQAKDASIVNFSSISFLLNMGELPSYAAAKAGIIGLTK 179 Query: 187 TLARELGEAGIRVNAVLPGAVVTERQTALWRDASSDRQFLDLQCLKFRVEPTHIADSVLF 246 +LA LG IRVN +LPG +VTERQ LW QCLK + ++ LF Sbjct: 180 SLAGRLGPENIRVNTLLPGMIVTERQKELWLTDEGITATTARQCLKRTLVAADLSGPCLF 239 Query: 247 LASPQAAAVTGQNLIVDAGL 266 LAS ++A+T Q++IVD GL Sbjct: 240 LASSASSAITAQSIIVDGGL 259