BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0113.p (295 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3058 [R] COG2321 Predicted metalloprotease Ype Yersinia pestis 316 4e-86 ypfJ [R] COG2321 Predicted metalloprotease Eco Escherichia coli K12 310 2e-84 Z3734 [R] COG2321 Predicted metalloprotease EcZ Escherichia coli... 310 2e-84 ECs3337 [R] COG2321 Predicted metalloprotease Ecs Escherichia co... 310 2e-84 PA4717 [R] COG2321 Predicted metalloprotease Pae Pseudomonas aer... 310 3e-84 >YPO3058 [R] COG2321 Predicted metalloprotease Ype Yersinia pestis Length = 288 Score = 316 bits (810), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 162/301 (53%), Positives = 205/301 (68%), Gaps = 23/301 (7%) Query: 1 MKWEGNRESDNVEDRRGEDGGGGGGGGF-----GFGGRSIGLGTVAVALVASYFLGINPL 55 M+W+G RES+NVEDRRG GGGGF G GG +I + + LVA Y+ G++ Sbjct: 1 MRWQGRRESNNVEDRRGN---ASGGGGFRPPIRGKGGVAI----LIIVLVAGYY-GVDLT 52 Query: 56 TMLNLLSGGGSPAPVQQQAPAHKP----SPNDQMARFVSTVLADTEDTWGQIFANNGKQY 111 +LN GG P Q Q P P + +DQ A+F S +LADTEDTW IF G+ Y Sbjct: 53 PLLN----GGDPLS-QTQTPPRSPKAVSTQDDQYAKFTSVILADTEDTWKPIFQKMGRTY 107 Query: 112 VQPKLVLFSGSTPTACGTGQTATGPFYCPGDQKVYIDLSFYELMKQRFKVSGNFAQAYVI 171 PKLV++ G+T T CGTGQ+ GPFYCP D +YIDLSFYE MK + G+FAQAYVI Sbjct: 108 QDPKLVMYRGATQTGCGTGQSVMGPFYCPADSTIYIDLSFYEDMKNKLGAGGDFAQAYVI 167 Query: 172 AHEVGHHVQHLMGISDKVDAARRNATEKQANAMSVRLELQADCFAGVWAYHANQARHILE 231 AHEVGHHVQHLMGI KV ++ ++ + N +SV++ELQADCFAGVW A + + +LE Sbjct: 168 AHEVGHHVQHLMGIDAKVRQQQQGVSQAEGNRLSVKMELQADCFAGVWG-KAMEEQQVLE 226 Query: 232 EGDIEDALNAASAIGDDALQRQARGVVVPDSFTHGSSAQRVTWFKRGISEGKVSACNTFG 291 GD+++ALNAA AIGDD LQ+Q++G VVPDSFTHG+S QR TWFKRG G ++CNTF Sbjct: 227 AGDLQEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYTWFKRGFDSGDPNSCNTFA 286 Query: 292 A 292 + Sbjct: 287 S 287 >ypfJ [R] COG2321 Predicted metalloprotease Eco Escherichia coli K12 Length = 287 Score = 310 bits (795), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 164/293 (55%), Positives = 199/293 (67%), Gaps = 11/293 (3%) Query: 1 MKWEGNRESDNVEDRRGEDGGGGGGGG-FGFGGRSIGLGTVAVALVASYFLGINPLTMLN 59 M+W+G RESDNVEDRR GG GG F GL + V LVA Y+ G++ Sbjct: 1 MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVVLVAGYY-GVD------ 53 Query: 60 LLSGGGSPAPVQQQAPAHKPSPN-DQMARFVSTVLADTEDTWGQIFANNGKQYVQPKLVL 118 L+G + PV QQ SPN D+ A+F S +LA TEDTWGQ F GK Y QPKLV+ Sbjct: 54 -LTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMGKTYQQPKLVM 112 Query: 119 FSGSTPTACGTGQTATGPFYCPGDQKVYIDLSFYELMKQRFKVSGNFAQAYVIAHEVGHH 178 + G T T CG GQ+ GPFYCP D VYIDLSFY+ MK + G+FAQ YVIAHEVGHH Sbjct: 113 YRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFAQGYVIAHEVGHH 172 Query: 179 VQHLMGISDKVDAARRNATEKQANAMSVRLELQADCFAGVWAYHANQARHILEEGDIEDA 238 VQ L+GI KV ++NAT+ + N +SVR+ELQADCFAGVW H+ Q + +LE GD+E+A Sbjct: 173 VQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWG-HSMQQQGVLETGDLEEA 231 Query: 239 LNAASAIGDDALQRQARGVVVPDSFTHGSSAQRVTWFKRGISEGKVSACNTFG 291 LNAA AIGDD LQ+Q++G VVPDSFTHG+S QR +WFKRG G + CNTFG Sbjct: 232 LNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGDPAQCNTFG 284 >Z3734 [R] COG2321 Predicted metalloprotease EcZ Escherichia coli O157:H7 EDL933 Length = 287 Score = 310 bits (795), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 164/293 (55%), Positives = 199/293 (67%), Gaps = 11/293 (3%) Query: 1 MKWEGNRESDNVEDRRGEDGGGGGGGG-FGFGGRSIGLGTVAVALVASYFLGINPLTMLN 59 M+W+G RESDNVEDRR GG GG F GL + V LVA Y+ G++ Sbjct: 1 MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVVLVAGYY-GVD------ 53 Query: 60 LLSGGGSPAPVQQQAPAHKPSPN-DQMARFVSTVLADTEDTWGQIFANNGKQYVQPKLVL 118 L+G + PV QQ SPN D+ A+F S +LA TEDTWGQ F GK Y QPKLV+ Sbjct: 54 -LTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMGKTYQQPKLVM 112 Query: 119 FSGSTPTACGTGQTATGPFYCPGDQKVYIDLSFYELMKQRFKVSGNFAQAYVIAHEVGHH 178 + G T T CG GQ+ GPFYCP D VYIDLSFY+ MK + G+FAQ YVIAHEVGHH Sbjct: 113 YRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFAQGYVIAHEVGHH 172 Query: 179 VQHLMGISDKVDAARRNATEKQANAMSVRLELQADCFAGVWAYHANQARHILEEGDIEDA 238 VQ L+GI KV ++NAT+ + N +SVR+ELQADCFAGVW H+ Q + +LE GD+E+A Sbjct: 173 VQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWG-HSMQQQGVLETGDLEEA 231 Query: 239 LNAASAIGDDALQRQARGVVVPDSFTHGSSAQRVTWFKRGISEGKVSACNTFG 291 LNAA AIGDD LQ+Q++G VVPDSFTHG+S QR +WFKRG G + CNTFG Sbjct: 232 LNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGDPAQCNTFG 284 >ECs3337 [R] COG2321 Predicted metalloprotease Ecs Escherichia coli O157:H7 Length = 287 Score = 310 bits (795), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 164/293 (55%), Positives = 199/293 (67%), Gaps = 11/293 (3%) Query: 1 MKWEGNRESDNVEDRRGEDGGGGGGGG-FGFGGRSIGLGTVAVALVASYFLGINPLTMLN 59 M+W+G RESDNVEDRR GG GG F GL + V LVA Y+ G++ Sbjct: 1 MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVVLVAGYY-GVD------ 53 Query: 60 LLSGGGSPAPVQQQAPAHKPSPN-DQMARFVSTVLADTEDTWGQIFANNGKQYVQPKLVL 118 L+G + PV QQ SPN D+ A+F S +LA TEDTWGQ F GK Y QPKLV+ Sbjct: 54 -LTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMGKTYQQPKLVM 112 Query: 119 FSGSTPTACGTGQTATGPFYCPGDQKVYIDLSFYELMKQRFKVSGNFAQAYVIAHEVGHH 178 + G T T CG GQ+ GPFYCP D VYIDLSFY+ MK + G+FAQ YVIAHEVGHH Sbjct: 113 YRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFAQGYVIAHEVGHH 172 Query: 179 VQHLMGISDKVDAARRNATEKQANAMSVRLELQADCFAGVWAYHANQARHILEEGDIEDA 238 VQ L+GI KV ++NAT+ + N +SVR+ELQADCFAGVW H+ Q + +LE GD+E+A Sbjct: 173 VQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWG-HSMQQQGVLETGDLEEA 231 Query: 239 LNAASAIGDDALQRQARGVVVPDSFTHGSSAQRVTWFKRGISEGKVSACNTFG 291 LNAA AIGDD LQ+Q++G VVPDSFTHG+S QR +WFKRG G + CNTFG Sbjct: 232 LNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGDPAQCNTFG 284 >PA4717 [R] COG2321 Predicted metalloprotease Pae Pseudomonas aeruginosa Length = 297 Score = 310 bits (793), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 177/298 (59%), Positives = 215/298 (72%), Gaps = 4/298 (1%) Query: 1 MKWEGNRESDNVEDRRGEDGGGGGGGGFGFGGRSIGLGTVAVALVASYFLGINPLTML-N 59 M W R SDNV D RGE G GGGGG GG+ + LG VA+ +V +G +P+ +L + Sbjct: 1 MLWRKGRRSDNVIDARGEGGAGGGGGMRI-GGKGLSLGGVAIVVVVGLLMGQDPMQILGS 59 Query: 60 LLSGGGSPAP-VQQQAPAHKPSPNDQMARFVSTVLADTEDTWGQIFANNGKQYVQPKLVL 118 LL SPAP QQQA P+ ND+ + FV ++L DTEDTW QIFA+ QY QPKLVL Sbjct: 60 LLGQMDSPAPATQQQAGGRAPAANDEQSEFVRSILGDTEDTWEQIFASGQAQYQQPKLVL 119 Query: 119 FSGSTPTACGTGQTATGPFYCPGDQKVYIDLSFYELMKQRFKVSGNFAQAYVIAHEVGHH 178 FS +ACG +ATGPFYCP D++VY+DL F+ M+QRF +G+FAQAYVIAHEVGHH Sbjct: 120 FSNGVNSACGFASSATGPFYCPADRRVYLDLEFFREMEQRFSAAGDFAQAYVIAHEVGHH 179 Query: 179 VQHLMGISDKVDAAR-RNATEKQANAMSVRLELQADCFAGVWAYHANQARHILEEGDIED 237 VQ+LMGIS K++AAR R A + AN +SVR ELQADCFAGVWA A Q + LE GDIE+ Sbjct: 180 VQNLMGISAKINAARQRGARMEGANGLSVRQELQADCFAGVWANRAQQRLNWLEPGDIEE 239 Query: 238 ALNAASAIGDDALQRQARGVVVPDSFTHGSSAQRVTWFKRGISEGKVSACNTFGAKEL 295 ALNAA+AIGDD LQRQ RG+VVPDSFTHGSSAQR+ WFK G G ++C+TF A+ L Sbjct: 240 ALNAANAIGDDRLQRQGRGMVVPDSFTHGSSAQRMRWFKTGFESGSPASCDTFKAQTL 297