BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0102.p (431 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ycdG [F] COG2233 Xanthine/uracil permeases Eco Escherichia coli K12 622 e-178 ZycdG [F] COG2233 Xanthine/uracil permeases EcZ Escherichia coli... 618 e-177 ECs1252 [F] COG2233 Xanthine/uracil permeases Ecs Escherichia co... 618 e-177 AGl3468 [F] COG2233 Xanthine/uracil permeases Atu Agrobacterium ... 511 e-144 BMEII0825 Non COG 483 e-136 >ycdG [F] COG2233 Xanthine/uracil permeases Eco Escherichia coli K12 Length = 464 Score = 622 bits (1604), Expect = e-178, Method: Compositional matrix adjust. Identities = 309/425 (72%), Positives = 365/425 (85%), Gaps = 2/425 (0%) Query: 6 FPQWRLRQSTNDGQGAVIAADERLPAPQTLAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 FP W+L+ ++ + V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 FPHWQLKSTSTES--GVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLMVGGRVPSYLGSSFSFIGLVIAVTGYAGSGPNANLGVALGGIIACGAVY 125 MSG+GTLLFF + GGRVPSYLGSS +F+G+VIA TG+ G G N N+ +ALGGIIACG VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 AVIGLIVSGVGTRWIESLMPPVVTGAVVAVIGLNLAPIAVKGVSGSSFDSWMALATILCV 185 VIGL+V +GTRWIE LMPPVVTGAVV IGLNLAPIAVK VS S+FDSWMA+ T+LC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCI 205 Query: 186 GFVAVFTRGMLQRLLILIGLLLAYVLYAVLTNGMGLGKPIDFSTVANAAWFGLPHFAAPV 245 G VAVFTRGM+QRLLIL+GL++A +LY V+TN +GLGK +DF+ V++AAWFGLPHF+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FQGSAMALLAPVAIILVAENLGHIKAVSAMTGQNLDRYIGRAFIGDGLATMLSGSVGGTG 305 F G AM L+APVA+ILVAENLGH+KAV+ MTG+N+D Y+GRAF+GDGLATMLSGSVGG+G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAILLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA+LLGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKMGGFALGGIGTATFGAIILHA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L +GGF LGGIGTATFGAI+L+A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLKRR 430 LL R+ Sbjct: 446 LLSRK 450 >ZycdG [F] COG2233 Xanthine/uracil permeases EcZ Escherichia coli O157:H7 EDL933 Length = 464 Score = 618 bits (1594), Expect = e-177, Method: Compositional matrix adjust. Identities = 308/425 (72%), Positives = 362/425 (85%), Gaps = 2/425 (0%) Query: 6 FPQWRLRQSTNDGQGAVIAADERLPAPQTLAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 P W+L+ ++ + V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 LPHWQLKSTSTES--GVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLMVGGRVPSYLGSSFSFIGLVIAVTGYAGSGPNANLGVALGGIIACGAVY 125 MSG+GTLLFF + GGRVPSYLGSS +F+G+VIA TG+ G G N N+ +ALGGIIACG VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 AVIGLIVSGVGTRWIESLMPPVVTGAVVAVIGLNLAPIAVKGVSGSSFDSWMALATILCV 185 VIGL+V +GTRWIE LMPPVVTGAVV IGLNLAPIAVK VS S FDSWMA+ T+LC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASGFDSWMAVMTVLCI 205 Query: 186 GFVAVFTRGMLQRLLILIGLLLAYVLYAVLTNGMGLGKPIDFSTVANAAWFGLPHFAAPV 245 G VAVFTRGM+QRLLIL+GL++A +LY V+TN +GLGK +DF+ V++AAWFGLPHF+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FQGSAMALLAPVAIILVAENLGHIKAVSAMTGQNLDRYIGRAFIGDGLATMLSGSVGGTG 305 F G AM L+APVA+ILVAENLGH+KAV+ MTG+N+D Y+GRAF+GDGLATMLSGSVG +G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGSSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAILLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA+LLGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKMGGFALGGIGTATFGAIILHA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L +GGF LGGIGTATFGAI+L+A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLKRR 430 LL RR Sbjct: 446 LLSRR 450 >ECs1252 [F] COG2233 Xanthine/uracil permeases Ecs Escherichia coli O157:H7 Length = 464 Score = 618 bits (1594), Expect = e-177, Method: Compositional matrix adjust. Identities = 308/425 (72%), Positives = 362/425 (85%), Gaps = 2/425 (0%) Query: 6 FPQWRLRQSTNDGQGAVIAADERLPAPQTLAMGVQHVVAMFGSTVLAPLLMGFDPNLAIL 65 P W+L+ ++ + V+A DERLP QT MGVQH VAMFG+TVL P+LMG DPNL+IL Sbjct: 28 LPHWQLKSTSTES--GVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIL 85 Query: 66 MSGVGTLLFFLMVGGRVPSYLGSSFSFIGLVIAVTGYAGSGPNANLGVALGGIIACGAVY 125 MSG+GTLLFF + GGRVPSYLGSS +F+G+VIA TG+ G G N N+ +ALGGIIACG VY Sbjct: 86 MSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVY 145 Query: 126 AVIGLIVSGVGTRWIESLMPPVVTGAVVAVIGLNLAPIAVKGVSGSSFDSWMALATILCV 185 VIGL+V +GTRWIE LMPPVVTGAVV IGLNLAPIAVK VS S FDSWMA+ T+LC+ Sbjct: 146 TVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASGFDSWMAVMTVLCI 205 Query: 186 GFVAVFTRGMLQRLLILIGLLLAYVLYAVLTNGMGLGKPIDFSTVANAAWFGLPHFAAPV 245 G VAVFTRGM+QRLLIL+GL++A +LY V+TN +GLGK +DF+ V++AAWFGLPHF+ P Sbjct: 206 GLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPA 265 Query: 246 FQGSAMALLAPVAIILVAENLGHIKAVSAMTGQNLDRYIGRAFIGDGLATMLSGSVGGTG 305 F G AM L+APVA+ILVAENLGH+KAV+ MTG+N+D Y+GRAF+GDGLATMLSGSVG +G Sbjct: 266 FNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGSSG 325 Query: 306 VTTYAENIGVMAVTKIYSTLVFVVAAVIAILLGFSPKFGAVILTIPGAVLGGVSIVVFGL 365 VTTYAENIGVMAVTK+YSTLVFV AAVIA+LLGFSPKFGA+I TIP AV+GG SIVVFGL Sbjct: 326 VTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGL 385 Query: 366 ITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKMGGFALGGIGTATFGAIILHA 425 I V+GARIWV+N+VD S N NLI+ AVTLVLGAGDF L +GGF LGGIGTATFGAI+L+A Sbjct: 386 IAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNA 445 Query: 426 LLKRR 430 LL RR Sbjct: 446 LLSRR 450 >AGl3468 [F] COG2233 Xanthine/uracil permeases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 502 Score = 511 bits (1316), Expect = e-144, Method: Compositional matrix adjust. Identities = 271/434 (62%), Positives = 335/434 (77%), Gaps = 14/434 (3%) Query: 2 SGSYFPQWRLRQSTNDGQGAVIAADERLPAPQTLAMGVQHVVAMFGSTVLAPLLMGFDPN 61 +G YFP+WRL+ +G+ I DERLPA QT +G+QHVVAMFGSTVLAPL+MGFDPN Sbjct: 66 TGGYFPRWRLK---TEGR---IMPDERLPAGQTAVLGLQHVVAMFGSTVLAPLIMGFDPN 119 Query: 62 LAILMSGVGTLLFFLMVGGRVPSYLGSSFSFIGLVIAVTGYAGSGPNANLGVALGGIIAC 121 ++IL SG+ TL+FF+ VGGRVPSYLGSSF+FIG V+ TG A + ++ +ALGGIIA Sbjct: 120 VSILFSGISTLIFFIAVGGRVPSYLGSSFAFIGPVLVATGAAAGAASPDIALALGGIIAA 179 Query: 122 GAVYAVIGLIVSGVGTRWIESLMPPVVTGAVVAVIGLNLAPIAVKGVSGS--------SF 173 G +YA+IG+IV VG WIE LMPPV+TGA+VA IGL LAPIA+ SG+ Sbjct: 180 GVLYALIGVIVMIVGHNWIEKLMPPVLTGAIVAAIGLVLAPIAIASASGTGPGNPDGDQL 239 Query: 174 DSWMALATILCVGFVAVFTRGMLQRLLILIGLLLAYVLYAVLTNGMGLGKPIDFSTVANA 233 W+A+ T+ VG +AV+ GM +RL IL+G +AY+ Y VL NG GLGKP+DF+ VA A Sbjct: 240 SRWIAILTVTSVGAIAVYAPGMTRRLPILLGGAIAYLAYLVLANGFGLGKPVDFAGVAAA 299 Query: 234 AWFGLPHFAAPVFQGSAMALLAPVAIILVAENLGHIKAVSAMTGQNLDRYIGRAFIGDGL 293 AWFGLP F PVF A+AL+APV +ILVAENLGHIKA+ AMTG+NLD Y+GRAFIGDG+ Sbjct: 300 AWFGLPAFTTPVFSAPAIALIAPVVVILVAENLGHIKAIGAMTGRNLDPYLGRAFIGDGI 359 Query: 294 ATMLSGSVGGTGVTTYAENIGVMAVTKIYSTLVFVVAAVIAILLGFSPKFGAVILTIPGA 353 AT+ SG+ GGTG+TTYAEN+GVMA+T+I+STLVF+VAA++AI+LGFSPKFGA+I TIPG Sbjct: 360 ATIFSGAFGGTGMTTYAENMGVMAITRIFSTLVFIVAALVAIILGFSPKFGALIQTIPGP 419 Query: 354 VLGGVSIVVFGLITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKMGGFALGGI 413 V+GG+S+VVFGLI + RIWVENKVDFS NLI + LVLGAG+F L + GF L GI Sbjct: 420 VIGGLSVVVFGLIAATAGRIWVENKVDFSEPRNLITVGIALVLGAGNFKLNVAGFTLDGI 479 Query: 414 GTATFGAIILHALL 427 GTAT GAI + LL Sbjct: 480 GTATIGAIAFYHLL 493 >BMEII0825 Non COG Length = 426 Score = 483 bits (1244), Expect = e-136, Method: Compositional matrix adjust. Identities = 250/423 (59%), Positives = 325/423 (76%), Gaps = 6/423 (1%) Query: 5 YFPQWRLRQSTNDGQGAVIAADERLPAPQTLAMGVQHVVAMFGSTVLAPLLMGFDPNLAI 64 YFP WRL + AV+ DERLPA + MG+QH++AM GST++APLLMGFDPN+A+ Sbjct: 3 YFPSWRLTSN------AVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAV 56 Query: 65 LMSGVGTLLFFLMVGGRVPSYLGSSFSFIGLVIAVTGYAGSGPNANLGVALGGIIACGAV 124 SG+GTLLFFL+ GRVPSYLGSSF+FI +VIA TGY+GSGPN N+ +ALGGIIACGA+ Sbjct: 57 FFSGIGTLLFFLITAGRVPSYLGSSFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGAL 116 Query: 125 YAVIGLIVSGVGTRWIESLMPPVVTGAVVAVIGLNLAPIAVKGVSGSSFDSWMALATILC 184 Y++IGLIV +GT W+E LMPP VTGA+ IGLNLAP+A+ + G+ + +AL T+LC Sbjct: 117 YSLIGLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQLKGTGAHTSIALLTVLC 176 Query: 185 VGFVAVFTRGMLQRLLILIGLLLAYVLYAVLTNGMGLGKPIDFSTVANAAWFGLPHFAAP 244 + ++ + +RL +L LL Y+L + NG+G+ IDF+ V NAAWFGLPHF P Sbjct: 177 MAMISAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTP 236 Query: 245 VFQGSAMALLAPVAIILVAENLGHIKAVSAMTGQNLDRYIGRAFIGDGLATMLSGSVGGT 304 F A+ L+APVAI+LVAENLGHIKA+ ++TG+N+D YIGR F DGLATM+SG+ GGT Sbjct: 237 AFNWQAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGT 296 Query: 305 GVTTYAENIGVMAVTKIYSTLVFVVAAVIAILLGFSPKFGAVILTIPGAVLGGVSIVVFG 364 GVTTYAENIGVMA+TK+YSTL+FV+AA++A++LG SPKFGA++ TIP VL G+++ VFG Sbjct: 297 GVTTYAENIGVMAMTKVYSTLIFVIAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFG 356 Query: 365 LITVSGARIWVENKVDFSNNTNLIVAAVTLVLGAGDFTLKMGGFALGGIGTATFGAIILH 424 LI + ARIW+ NKVDF+++ NL V L+ GAGDFTL +G FALGGI T+T A++L+ Sbjct: 357 LIASAMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNFALGGIATSTLAALVLY 416 Query: 425 ALL 427 LL Sbjct: 417 QLL 419