BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0090.p (514 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0797 [J] COG0013 Alanyl-tRNA synthetase Rso Ralstonia solanac... 697 0.0 NMA1788 [J] COG0013 Alanyl-tRNA synthetase NmA Neisseria meningi... 603 e-172 NMB1595 [J] COG0013 Alanyl-tRNA synthetase Nme Neisseria meningi... 597 e-170 PA0903 [J] COG0013 Alanyl-tRNA synthetase Pae Pseudomonas aerugi... 593 e-169 STM2827 [J] COG0013 Alanyl-tRNA synthetase Sty Salmonella typhim... 592 e-169 >RSc0797 [J] COG0013 Alanyl-tRNA synthetase Rso Ralstonia solanacearum Length = 884 Score = 697 bits (1799), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/407 (82%), Positives = 358/407 (87%), Gaps = 8/407 (1%) Query: 1 MNSAEIRDKFLKFFESKEHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGTDKRNYVRA 60 M +++IR KFL FFE+K HT+VRSS LVPGNDPTLLFTNSGMVQFKDVFLGTDKR YVRA Sbjct: 1 MKASDIRQKFLTFFETKGHTVVRSSPLVPGNDPTLLFTNSGMVQFKDVFLGTDKRPYVRA 60 Query: 61 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLTQVYGLP 120 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKR++L WAWELLTQ Y LP Sbjct: 61 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRDALVWAWELLTQEYKLP 120 Query: 121 ADKLWATVYQTDDEAYDIWTKEIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPCSE 180 ADKLWATVYQTDDEAYDIWTK IGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPCSE Sbjct: 121 ADKLWATVYQTDDEAYDIWTKVIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPCSE 180 Query: 181 IFYDHGPDIWGGPPGSPDADGDRYIEIWNNVFMQFDRQLDPATGEYTLTPLPAPCVDTGM 240 IFYDHGP+IWGGPPGSP+ADGDRYIEIWNNVFMQFDRQLDP TGEYTLTPLPAPCVDTGM Sbjct: 181 IFYDHGPEIWGGPPGSPEADGDRYIEIWNNVFMQFDRQLDPQTGEYTLTPLPAPCVDTGM 240 Query: 241 GLERLAAILQHVHSNYEIDLFQALIKAAARETGISDLSNASLRVIADHIRATSFLIVDGV 300 G+ERLAAILQHVHSNYEIDLFQAL+ AAARET DL+N SLRVIADHIRA +FLIVDGV Sbjct: 241 GMERLAAILQHVHSNYEIDLFQALVSAAARETNTKDLANNSLRVIADHIRACAFLIVDGV 300 Query: 301 IPGNEGRGYVLRRIIRRALRHGHKLGQTKPFFHKLVKDLVVQMGAAYPELPEAAERVEMV 360 IPGNEGRGYVLRRIIRRA+RHG+KLG FFHKLV DLV +MG AYPEL EA +RV V Sbjct: 301 IPGNEGRGYVLRRIIRRAIRHGYKLGCRAAFFHKLVDDLVKEMGEAYPELREARDRVVDV 360 Query: 361 LKQEEERFGETLEHGMKILEAALA--------SNSSKLDGETAFTLY 399 L+ EE RF ET+EHGM IL+ AL LDGE AF L+ Sbjct: 361 LRTEEARFFETIEHGMSILDGALGELKAAGKDEKQRMLDGELAFKLH 407 >NMA1788 [J] COG0013 Alanyl-tRNA synthetase NmA Neisseria meningitidis Z2491 Length = 874 Score = 603 bits (1555), Expect = e-172, Method: Compositional matrix adjust. Identities = 281/408 (68%), Positives = 326/408 (79%), Gaps = 8/408 (1%) Query: 1 MNSAEIRDKFLKFFESKEHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGTDKRNYVRA 60 M ++E+R KFLKFFE+K HT+VRSSSLVP +DPTLLFTN+GM QFKDVFLG DKR Y RA Sbjct: 1 MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQFKDVFLGFDKRPYSRA 60 Query: 61 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLT--QVYG 118 + Q+C+RAGGKHNDLENVGYTARHHTFFEM+GN+SFGDYFKR+++ +AWE LT + Sbjct: 61 TTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFKRDAIHFAWEFLTSPEWLN 120 Query: 119 LPADKLWATVYQTDDEAYDIWTKEIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPC 178 +P DKL ATVY DDEAY+IW EIG+P ER+VRIGDNKGA Y SDNFWQM +TGPCGPC Sbjct: 121 IPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYVSDNFWQMGDTGPCGPC 180 Query: 179 SEIFYDHGPDIWGGPPGSPDADGDRYIEIWNNVFMQFDRQLDPATGEYTLTPLPAPCVDT 238 SEIFYDHG +IWGG PGSP+ DGDR+IEIWN VFMQF+R + + PLP P VDT Sbjct: 181 SEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRD-----EQGNMNPLPKPSVDT 235 Query: 239 GMGLERLAAILQHVHSNYEIDLFQALIKAAARETGIS-DLSNASLRVIADHIRATSFLIV 297 GMGLER+AA++QHVHSNYEIDLFQ L+KA ARETG + + SL+VIADHIR+ SFLI Sbjct: 236 GMGLERMAAVMQHVHSNYEIDLFQDLLKAVARETGAAFSMDEPSLKVIADHIRSCSFLIA 295 Query: 298 DGVIPGNEGRGYVLRRIIRRALRHGHKLGQTKPFFHKLVKDLVVQMGAAYPELPEAAERV 357 DGV+P NEGRGYVLRRIIRRA+RHG+KLGQ+KPFFHKLV DLV +MG AYPEL E ++ Sbjct: 296 DGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGGAYPELKEKQAQI 355 Query: 358 EMVLKQEEERFGETLEHGMKILEAALASNSSKLDGETAFTLYXPASPP 405 E LK EE RF +TLE GM +LE ALA LDGE F LY P Sbjct: 356 EEALKNEESRFAQTLETGMALLENALAKGGKTLDGEIIFKLYDTYGFP 403 >NMB1595 [J] COG0013 Alanyl-tRNA synthetase Nme Neisseria meningitidis MC58 Length = 874 Score = 597 bits (1540), Expect = e-170, Method: Compositional matrix adjust. Identities = 280/408 (68%), Positives = 324/408 (79%), Gaps = 8/408 (1%) Query: 1 MNSAEIRDKFLKFFESKEHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGTDKRNYVRA 60 M ++E+R KFLKFFE+K HT+VRSSSLVP +DPTLLFTN+GM QFKDVFLG DKR Y RA Sbjct: 1 MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQFKDVFLGFDKRPYSRA 60 Query: 61 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLT--QVYG 118 + Q+C+RAGGKHNDLENVGYTARHHTFFEM+GN+SFGDYFKR+++ +AWE LT + Sbjct: 61 TTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFKRDAIHFAWEFLTSPEWLN 120 Query: 119 LPADKLWATVYQTDDEAYDIWTKEIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPC 178 +P DKL ATVY DDEAY+IW EIG+P ER+VRIGDNKGA YASDNFWQM +TGPCGPC Sbjct: 121 IPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYASDNFWQMGDTGPCGPC 180 Query: 179 SEIFYDHGPDIWGGPPGSPDADGDRYIEIWNNVFMQFDRQLDPATGEYTLTPLPAPCVDT 238 SEIFYDHG +IWGG PGSP+ DGDR+IEIWN VFMQF+R + + PLP P VDT Sbjct: 181 SEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRD-----EQGNMNPLPKPSVDT 235 Query: 239 GMGLERLAAILQHVHSNYEIDLFQALIKAAARETGI-SDLSNASLRVIADHIRATSFLIV 297 GMGLER+AA++QHVHSNYEIDLFQ L+KA ARETG + SL+VIADHIR+ SFLI Sbjct: 236 GMGLERIAAVMQHVHSNYEIDLFQDLLKAVARETGAPFRMEEPSLKVIADHIRSCSFLIA 295 Query: 298 DGVIPGNEGRGYVLRRIIRRALRHGHKLGQTKPFFHKLVKDLVVQMGAAYPELPEAAERV 357 DGV+P NEGRGYVLRRIIRRA+RHG+KLGQ+KPFFHKLV DLV +MG AYPEL E ++ Sbjct: 296 DGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGGAYPELKEKQAQI 355 Query: 358 EMVLKQEEERFGETLEHGMKILEAALASNSSKLDGETAFTLYXPASPP 405 E LK EE RF +TLE GM +LE AL L GE F LY P Sbjct: 356 EEALKNEESRFAQTLETGMALLENALVKGGKTLGGEIIFKLYDTYGFP 403 >PA0903 [J] COG0013 Alanyl-tRNA synthetase Pae Pseudomonas aeruginosa Length = 874 Score = 593 bits (1529), Expect = e-169, Method: Compositional matrix adjust. Identities = 276/408 (67%), Positives = 322/408 (78%), Gaps = 8/408 (1%) Query: 1 MNSAEIRDKFLKFFESKEHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGTDKRNYVRA 60 M SAEIR+ FL+FFE K HT V SSSL+P NDPTLLFTN+GM QFKD FLG +KR Y RA Sbjct: 1 MKSAEIREAFLRFFEEKGHTRVASSSLIPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRA 60 Query: 61 ASVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLTQV--YG 118 + Q+C+RAGGKHNDLENVGYTARHHTFFEMLGN+SFGDYFKR+++ +AWE LT Sbjct: 61 TTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWEFLTGEKWLN 120 Query: 119 LPADKLWATVYQTDDEAYDIWTKEIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPC 178 LP +KLW TVY TDDEAYDIWTKE+G+P ER+VRIGDNKGAPYASDNFW M +TGPCGPC Sbjct: 121 LPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPYASDNFWAMGDTGPCGPC 180 Query: 179 SEIFYDHGPDIWGGPPGSPDADGDRYIEIWNNVFMQFDRQLDPATGEYTLTPLPAPCVDT 238 +EIF+DHGP+IWGGPPGSP+ DGDRYIEIWNNVFMQF+R T + + PLPAP VDT Sbjct: 181 TEIFFDHGPEIWGGPPGSPEEDGDRYIEIWNNVFMQFNR-----TADGVMHPLPAPSVDT 235 Query: 239 GMGLERLAAILQHVHSNYEIDLFQALIKAAARETGISDLSNASLRVIADHIRATSFLIVD 298 GMGLER++A+LQHVHSNYEIDLFQ L+KA+A G ++ SL+V+ADHIR+ SFLI D Sbjct: 236 GMGLERVSAVLQHVHSNYEIDLFQNLLKASAEAIGCANDDAPSLKVVADHIRSCSFLIAD 295 Query: 299 GVIPGNEGRGYVLRRIIRRALRHGHKLGQTKPFFHKLVKDLVVQMGAAYPELPEAAERVE 358 GV+P NEGRGYVLRRIIRRA RHG+KLG FFHK+V LV +MG A+PEL + +E Sbjct: 296 GVLPSNEGRGYVLRRIIRRACRHGNKLGARGTFFHKIVAALVAEMGDAFPELKQQQAHIE 355 Query: 359 MVLKQEEERFGETLEHGMKILEAALAS-NSSKLDGETAFTLYXPASPP 405 VLK EEE+F +TLE G+KILE LA S + G F LY P Sbjct: 356 RVLKTEEEQFAKTLEQGLKILEQDLAELQGSVIPGNVVFKLYDTYGFP 403 >STM2827 [J] COG0013 Alanyl-tRNA synthetase Sty Salmonella typhimurium LT2 Length = 876 Score = 592 bits (1525), Expect = e-169, Method: Compositional matrix adjust. Identities = 275/407 (67%), Positives = 324/407 (79%), Gaps = 8/407 (1%) Query: 2 NSAEIRDKFLKFFESKEHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGTDKRNYVRAA 61 ++AEIR FL FF SK H +V SSSLVP NDPTLLFTN+GM QFKDVFLG DKRNY RA Sbjct: 4 STAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRNYSRAT 63 Query: 62 SVQRCLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRESLKWAWELLTQV--YGL 119 + QRC+RAGGKHNDLENVGYTARHHTFFEMLGN+SFGDYFK +++++AWELLT + L Sbjct: 64 TSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTGENWFAL 123 Query: 120 PADKLWATVYQTDDEAYDIWTKEIGLPPERVVRIGDNKGAPYASDNFWQMAETGPCGPCS 179 P ++LW TVY+TDDEAY+IW KE+G+P ER++RIGDNKGAPYASDNFWQM +TGPCGPC+ Sbjct: 124 PKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCT 183 Query: 180 EIFYDHGPDIWGGPPGSPDADGDRYIEIWNNVFMQFDRQLDPATGEYTLTPLPAPCVDTG 239 EIFYDHG IWGGPPGSP+ DGDRYIEIWN VFMQF+RQ D T+ PLP P VDTG Sbjct: 184 EIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADG-----TMEPLPKPSVDTG 238 Query: 240 MGLERLAAILQHVHSNYEIDLFQALIKAAARETGISDLSNASLRVIADHIRATSFLIVDG 299 MGLER+AA+LQHV+SNY+IDLF+ LI+A A+ TG +DL N SLRVIADHIR+ +FL+ DG Sbjct: 239 MGLERIAAVLQHVNSNYDIDLFRTLIEAVAKVTGATDLGNKSLRVIADHIRSCAFLVADG 298 Query: 300 VIPGNEGRGYVLRRIIRRALRHGHKLGQTKPFFHKLVKDLVVQMGAAYPELPEAAERVEM 359 V+P NE RGYVLRRIIRRA+RHG+ LG + FF+KLV L+ MG+A EL +VE Sbjct: 299 VLPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIEVMGSAGEELKRQQAQVEQ 358 Query: 360 VLKQEEERFGETLEHGMKILEAALAS-NSSKLDGETAFTLYXPASPP 405 VLK EEE+F TLE G+ +L+ LA LDGETAF LY P Sbjct: 359 VLKTEEEQFARTLERGLALLDEELAKLQGDTLDGETAFRLYDTYGFP 405