BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0047.p (494 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0708 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase... 785 0.0 NMA1952 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase... 760 0.0 NMB1694 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase... 756 0.0 PA5237 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase ... 749 0.0 YPO3769 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase... 731 0.0 >RSc0708 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Rso Ralstonia solanacearum Length = 503 Score = 785 bits (2028), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/501 (75%), Positives = 437/501 (87%), Gaps = 9/501 (1%) Query: 1 MKYTDLRDFISQLQQKGELKRVSHPVSSHLEMTEIADRTLRAEGPALLFEQ----VDKKN 56 M+Y DLRDF++QL++ GEL+R+ PVS LEMTE+ DR LRAEGPA++FE+ + Sbjct: 1 MQYRDLRDFLAQLERIGELRRIRVPVSPRLEMTEVCDRLLRAEGPAVVFERPADGAQTYD 60 Query: 57 IPVLANLFGTPHRVALGMGADSISELRRIGHLLARLKEPEPPKGIKDVLDLGGLVKSLWD 116 +PVLANLFGTP RVALGMGA+S+ ELR +G LL+ LKEPEPP+G+++ L + K++WD Sbjct: 61 MPVLANLFGTPRRVALGMGAESLDELRDVGRLLSALKEPEPPRGLREAGKLWTMAKAVWD 120 Query: 117 MAPKERGSAPCQDVVWEGKEVDLSRLPIQHCWPGDIAPLITWGLVITKGPNKKRQNLGIY 176 MAP++ S CQ++V EG +VDLSR+P+Q CWPGD APL+TWGLV+T+GP+KKRQNLGIY Sbjct: 121 MAPRKVSSPACQEIVLEGDDVDLSRIPVQTCWPGDAAPLVTWGLVVTRGPHKKRQNLGIY 180 Query: 177 RQQVLGPNKVIMRWLAHRGGALDFREHCIANPGKPYPIAVALGADPATILGAVTPVPDSL 236 RQQV+ N+VIMRWLAHRGGALDFREH IA+PG+P+PIAVALGADPATILGAVTPVPD+L Sbjct: 181 RQQVINRNQVIMRWLAHRGGALDFREHAIAHPGQPFPIAVALGADPATILGAVTPVPDTL 240 Query: 237 SEYQFAGLLRGSRTELVKAMG-----SDLRVPASAEIVLEGHIYPDEKHASGFEHALEGP 291 SEYQFAGLLRGSRTEL + + + L+VPA AEIVLEGHI PD H SG++HALEGP Sbjct: 241 SEYQFAGLLRGSRTELAQCLTPSLAQAQLQVPAGAEIVLEGHIQPDPAHPSGYQHALEGP 300 Query: 292 YGDHTGYYNEQDWFPVFTIDRITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQ 351 +GDHTGYYNEQDWFPVFT++RITMRRD IYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQ Sbjct: 301 FGDHTGYYNEQDWFPVFTVERITMRRDPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQ 360 Query: 352 FAEITDFYLPPEGCSYRMAVVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVDI 411 F EI DFYLPPEGCSYRMA+V MKK YAGHAKRVMFGVWSFLRQFMYTKFIVVVD+DVD+ Sbjct: 361 FPEIADFYLPPEGCSYRMALVSMKKQYAGHAKRVMFGVWSFLRQFMYTKFIVVVDDDVDL 420 Query: 412 RDWKEVIWAITTRVDPVRDTVMVDNTPIDYLDFASPISGLGSKMGIDATNKWPGETSREW 471 RDWKEVIWAITTRVDP RDTVMV+NTPIDYLDFASP+SGLGSKMGIDATNKWPGET+REW Sbjct: 421 RDWKEVIWAITTRVDPARDTVMVENTPIDYLDFASPVSGLGSKMGIDATNKWPGETTREW 480 Query: 472 GTPIVMSDDVKKRVDAIWQDL 492 G PIVM VK RVDA+W+ L Sbjct: 481 GQPIVMDAAVKSRVDAMWETL 501 >NMA1952 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases NmA Neisseria meningitidis Z2491 Length = 492 Score = 760 bits (1962), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/499 (74%), Positives = 425/499 (85%), Gaps = 12/499 (2%) Query: 1 MKYTDLRDFISQLQQKGELKRVSHPVSSHLEMTEIADRTLRAEGPALLFEQVDKKN---- 56 MKY DLRDFI+ L+Q+G+LKR++HPVS HLEMTEIADR LRAEGPALLFE K + Sbjct: 1 MKYKDLRDFIAMLEQQGKLKRIAHPVSPHLEMTEIADRVLRAEGPALLFEHPVKPDGTRY 60 Query: 57 -IPVLANLFGTPHRVALGMGADSISELRRIGHLLARLKEPEPPKGIKDVLDLGGLVKSLW 115 PVLANLFGTP RVA+GMGADS+S+LR IG LA LKEPEPPKGIKD L+K +W Sbjct: 61 DYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEPPKGIKDAFSKLPLLKDIW 120 Query: 116 DMAPKERGSAPCQDVVWEGKEVDLSRLPIQHCWPGDIAPLITWGLVITKGPNKKRQNLGI 175 MAP +APCQ++VWEG++VDL +LPIQHCWP D+APL+TWGL +T+GP+KKRQNLGI Sbjct: 121 SMAPNVVKNAPCQEIVWEGEDVDLYQLPIQHCWPEDVAPLVTWGLTVTRGPHKKRQNLGI 180 Query: 176 YRQQVLGPNKVIMRWLAHRGGALDFREHCIANPGKPYPIAVALGADPATILGAVTPVPDS 235 YRQQ++G NK+IMRWL+HRGGALD++E NP PYP+AV LG DPATILGAVTPVPD+ Sbjct: 181 YRQQLIGINKLIMRWLSHRGGALDYQEFRKLNPDTPYPVAVVLGCDPATILGAVTPVPDT 240 Query: 236 LSEYQFAGLLRGSRTELVKAMGSDLRVPASAEIVLEGHIYPDEKHASGFEHALEGPYGDH 295 LSEYQFAGLLRGSRTELVK +G+DL+VPA AEIVLEG I+P+E ALEGPYGDH Sbjct: 241 LSEYQFAGLLRGSRTELVKCIGNDLQVPARAEIVLEGVIHPNET-------ALEGPYGDH 293 Query: 296 TGYYNEQDWFPVFTIDRITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEI 355 TGYYNEQD FPVFT++RITMR + IYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQF EI Sbjct: 294 TGYYNEQDHFPVFTVERITMRENPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEI 353 Query: 356 TDFYLPPEGCSYRMAVVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVDIRDWK 415 TDFYLPPEGCSYRMAVV MKK YAGHAKRVM G WSFLRQFMYTKFI+VVD+DVD+RDWK Sbjct: 354 TDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMMGCWSFLRQFMYTKFIIVVDDDVDVRDWK 413 Query: 416 EVIWAITTRVDPVRDTVMVDNTPIDYLDFASPISGLGSKMGIDATNKWPGETSREWGTPI 475 EVIWA+TTR+DPVRDTV+++NTPIDYLDFASP+SGLG KMG+DATNKWPGET REWG I Sbjct: 414 EVIWAVTTRMDPVRDTVLMENTPIDYLDFASPVSGLGGKMGLDATNKWPGETDREWGRVI 473 Query: 476 VMSDDVKKRVDAIWQDLGI 494 V ++D IW++LG+ Sbjct: 474 KKDPAVTAKIDEIWEELGL 492 >NMB1694 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Nme Neisseria meningitidis MC58 Length = 494 Score = 756 bits (1953), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/499 (74%), Positives = 426/499 (85%), Gaps = 12/499 (2%) Query: 1 MKYTDLRDFISQLQQKGELKRVSHPVSSHLEMTEIADRTLRAEGPALLFEQVDKKN---- 56 MKY DLRDFI+ L+Q+G+LKRV+HP+S +LEMTEIADR LRAEGPALLFE K + Sbjct: 3 MKYKDLRDFIAMLEQQGKLKRVAHPISPYLEMTEIADRVLRAEGPALLFENPIKPDGTRY 62 Query: 57 -IPVLANLFGTPHRVALGMGADSISELRRIGHLLARLKEPEPPKGIKDVLDLGGLVKSLW 115 PVLANLFGTP RVA+GMGADS+S+LR IG LA LKEPEPPKGIKD L+K +W Sbjct: 63 GYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEPPKGIKDAFSKLPLLKDIW 122 Query: 116 DMAPKERGSAPCQDVVWEGKEVDLSRLPIQHCWPGDIAPLITWGLVITKGPNKKRQNLGI 175 MAP +APCQ++VWEG++VDL +LPIQHCWP D+APL+TWGL +T+GP+KKRQNLGI Sbjct: 123 SMAPNVVKNAPCQEIVWEGEDVDLYQLPIQHCWPEDVAPLVTWGLTVTRGPHKKRQNLGI 182 Query: 176 YRQQVLGPNKVIMRWLAHRGGALDFREHCIANPGKPYPIAVALGADPATILGAVTPVPDS 235 YRQQ++G NK+IMRWL+HRGGALD++E NP PYP+AV LG DPATILGAVTPVPD+ Sbjct: 183 YRQQLIGKNKLIMRWLSHRGGALDYQEFRKLNPDTPYPVAVVLGCDPATILGAVTPVPDT 242 Query: 236 LSEYQFAGLLRGSRTELVKAMGSDLRVPASAEIVLEGHIYPDEKHASGFEHALEGPYGDH 295 LSEYQFAGLLRGSRTELVK +G+DL+VPA AEIVLEG I+P+E ALEGPYGDH Sbjct: 243 LSEYQFAGLLRGSRTELVKCIGNDLQVPARAEIVLEGVIHPNET-------ALEGPYGDH 295 Query: 296 TGYYNEQDWFPVFTIDRITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEI 355 TGYYNEQD+FPVFT++RITMR + IYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQF EI Sbjct: 296 TGYYNEQDYFPVFTVERITMRENPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEI 355 Query: 356 TDFYLPPEGCSYRMAVVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVDIRDWK 415 TDFYLPPEGCSYRMAVV MKK YAGHAKRVM G WSFLRQFMYTKFI+VVD+DV++RDWK Sbjct: 356 TDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMMGCWSFLRQFMYTKFIIVVDDDVNVRDWK 415 Query: 416 EVIWAITTRVDPVRDTVMVDNTPIDYLDFASPISGLGSKMGIDATNKWPGETSREWGTPI 475 EVIWA+TTR+DPVRDTV+V+NTPIDYLDFASP+SGLG KMG+DATNKWPGET REWG I Sbjct: 416 EVIWAVTTRMDPVRDTVLVENTPIDYLDFASPVSGLGGKMGLDATNKWPGETDREWGRVI 475 Query: 476 VMSDDVKKRVDAIWQDLGI 494 V ++D IW++LG+ Sbjct: 476 KKDPAVTAKIDGIWEELGL 494 >PA5237 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Pae Pseudomonas aeruginosa Length = 488 Score = 749 bits (1934), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/494 (72%), Positives = 414/494 (83%), Gaps = 7/494 (1%) Query: 1 MKYTDLRDFISQLQQKGELKRVSHPVSSHLEMTEIADRTLRAEGPALLFEQVDKKNIPVL 60 M + DLRDFI+QL+Q+G LKR+ P+S LEMTE+ DRTLRA+GPALLFE+ ++PVL Sbjct: 1 MTFKDLRDFIAQLEQRGALKRIQVPISPVLEMTEVCDRTLRAKGPALLFEKPTGFDMPVL 60 Query: 61 ANLFGTPHRVALGMGADSISELRRIGHLLARLKEPEPPKGIKDVLDLGGLVKSLWDMAPK 120 NLFGTP RVALGMGA+ + LR IG LLA+LKEPEPPKG+KD + + + MAPK Sbjct: 61 GNLFGTPERVALGMGAEDVGALREIGKLLAQLKEPEPPKGLKDAWAKLPMYRKVLSMAPK 120 Query: 121 ERGSAPCQDVVWEGKEVDLSRLPIQHCWPGDIAPLITWGLVITKGPNKKRQNLGIYRQQV 180 APCQ+VV EG++VDL RLP+Q CWPGD+ PLITWGL +T+GPNK+RQNLGIYRQQV Sbjct: 121 VLKDAPCQEVVEEGEDVDLGRLPVQTCWPGDVGPLITWGLTVTRGPNKERQNLGIYRQQV 180 Query: 181 LGPNKVIMRWLAHRGGALDFREHCIANPGKPYPIAVALGADPATILGAVTPVPDSLSEYQ 240 +G NKVIMRWL+HRGGALD+RE C +PG+PYP+AVALGADPATILGAVTPVPD+LSEY Sbjct: 181 IGRNKVIMRWLSHRGGALDYREWCQKHPGQPYPVAVALGADPATILGAVTPVPDTLSEYA 240 Query: 241 FAGLLRGSRTELVKAMGSDLRVPASAEIVLEGHIYPDEKHASGFEHALEGPYGDHTGYYN 300 FAGLLRG RTELVK GSDL+VPASAEIVLEG I+P E A EGPYGDHTGYYN Sbjct: 241 FAGLLRGHRTELVKCRGSDLQVPASAEIVLEGVIHPG-------EMADEGPYGDHTGYYN 293 Query: 301 EQDWFPVFTIDRITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEITDFYL 360 E D FPVFT++R+T R+ IYHSTYTG+PPDEPA+LGVALNEVFVP+LQKQF EI DFYL Sbjct: 294 EVDRFPVFTVERVTRRQKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEIVDFYL 353 Query: 361 PPEGCSYRMAVVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVDIRDWKEVIWA 420 PPEGCSYRMAVV MKK Y GHAKRVM GVWSFLRQFMYTKF++V D+D+D RDW +VIWA Sbjct: 354 PPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDIDARDWNDVIWA 413 Query: 421 ITTRVDPVRDTVMVDNTPIDYLDFASPISGLGSKMGIDATNKWPGETSREWGTPIVMSDD 480 ITTR+DP RDTVM+DNTPIDYLDFASP+SGLGSKMG+DAT+KWPGETSREWG IV + Sbjct: 414 ITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATHKWPGETSREWGRAIVKDEA 473 Query: 481 VKKRVDAIWQDLGI 494 V +R+DA+W LGI Sbjct: 474 VTRRIDALWSSLGI 487 >YPO3769 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Ype Yersinia pestis Length = 498 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/494 (69%), Positives = 411/494 (83%), Gaps = 7/494 (1%) Query: 1 MKYTDLRDFISQLQQKGELKRVSHPVSSHLEMTEIADRTLRAEGPALLFEQVDKKNIPVL 60 MKY DLRDF+S L+Q+GELKR+S P+ +LEMTEIADRTLRA GPALLFE ++PVL Sbjct: 4 MKYRDLRDFLSLLEQRGELKRISQPIDPYLEMTEIADRTLRAGGPALLFENPKGYSMPVL 63 Query: 61 ANLFGTPHRVALGMGADSISELRRIGHLLARLKEPEPPKGIKDVLDLGGLVKSLWDMAPK 120 NLFGT RVA+GMG + +S LR +G LLA LKEP+PPKG +D+ D K + +M K Sbjct: 64 CNLFGTAKRVAMGMGQEDVSALRDVGKLLAFLKEPDPPKGFRDLFDKLPKFKQVLNMPTK 123 Query: 121 ERGSAPCQDVVWEGKEVDLSRLPIQHCWPGDIAPLITWGLVITKGPNKKRQNLGIYRQQV 180 SAPCQ+ VW+G++VDLSR+P+ HCWP D APL++WGL IT+GP+K+RQNLGIYRQQV Sbjct: 124 RLNSAPCQEQVWQGEDVDLSRIPVMHCWPEDAAPLVSWGLTITRGPHKERQNLGIYRQQV 183 Query: 181 LGPNKVIMRWLAHRGGALDFREHCIANPGKPYPIAVALGADPATILGAVTPVPDSLSEYQ 240 LG NK+IMRWL+HRGGALD++E C A+PG+ +P+AVALGADPATIL AVTPVPD+LSEY Sbjct: 184 LGKNKLIMRWLSHRGGALDYQEWCEAHPGERFPVAVALGADPATILAAVTPVPDTLSEYA 243 Query: 241 FAGLLRGSRTELVKAMGSDLRVPASAEIVLEGHIYPDEKHASGFEHALEGPYGDHTGYYN 300 FAGLLRG +TE+VK + +DL VPASAEIVLEG+I + A EGPYGDHTGYYN Sbjct: 244 FAGLLRGHKTEVVKCLSNDLEVPASAEIVLEGYI-------EQGDMAPEGPYGDHTGYYN 296 Query: 301 EQDWFPVFTIDRITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEITDFYL 360 E D FPVFT+ IT R+DAIYHSTYTG+PPDEPAV+GVALNEVFVP+LQKQF EI DFYL Sbjct: 297 EIDNFPVFTVTHITQRQDAIYHSTYTGRPPDEPAVMGVALNEVFVPILQKQFPEIVDFYL 356 Query: 361 PPEGCSYRMAVVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVDIRDWKEVIWA 420 PPEGCSYR+AVV +KK YAGHAKRVM G+WSFLRQFMYTKF++V D+D++ RDW +VIWA Sbjct: 357 PPEGCSYRLAVVTIKKQYAGHAKRVMMGIWSFLRQFMYTKFVIVCDDDINARDWNDVIWA 416 Query: 421 ITTRVDPVRDTVMVDNTPIDYLDFASPISGLGSKMGIDATNKWPGETSREWGTPIVMSDD 480 ITTR+DP RDTV+++NTPIDYLDFASP+SGLGSKMG+DATNKWP ET REWG PI M +D Sbjct: 417 ITTRMDPSRDTVLIENTPIDYLDFASPVSGLGSKMGLDATNKWPAETPREWGRPIKMDED 476 Query: 481 VKKRVDAIWQDLGI 494 V+ R+DA+W +L I Sbjct: 477 VRARIDALWDELAI 490