BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0028.p (576 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2200 [V] COG1132 ABC-type multidrug transport system, ATPase ... 576 e-164 msbA [V] COG1132 ABC-type multidrug transport system, ATPase and... 460 e-129 ZmsbA [V] COG1132 ABC-type multidrug transport system, ATPase an... 460 e-129 ECs0997 [V] COG1132 ABC-type multidrug transport system, ATPase ... 460 e-129 STM0984 [V] COG1132 ABC-type multidrug transport system, ATPase ... 459 e-129 >RSc2200 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Rso Ralstonia solanacearum Length = 592 Score = 576 bits (1485), Expect = e-164, Method: Compositional matrix adjust. Identities = 290/574 (50%), Positives = 399/574 (69%), Gaps = 3/574 (0%) Query: 5 NIKRLAALHWPYKKRLALAFLGMIVTAATEPVVPYIFQVLLDKGFVGKPTFSLWLVPAAV 64 + KRL A P LA + M V AATE ++P + + LLD+GF G+ LW VPA + Sbjct: 19 HFKRLWAYLRPELSSFILAMVAMGVVAATEGIIPKVVKDLLDQGFGGEYAGKLWRVPAML 78 Query: 65 IGIFLIRGMATFTSTYMMTWVSTRILNELRRQMFARMLDLPIHFYATNTVGKVINSMMFE 124 +GI ++RG+A F +TY ++ VS ++L LR +MF R+L P FY NT +IN+++FE Sbjct: 79 VGIAVVRGVAQFGATYFLSLVSNKVLLNLRMKMFERLLQAPAAFYQRNTAASLINAVIFE 138 Query: 125 VQQIIDMVTKVFTSILRSALTVLGLLGWLLYLNWTLTIVTLVLLPLVSIVVRATGKRLKK 184 V Q++ ++T VF +++R ++TVL LL +L Y NW LT+V V+LP++ ++ +RL+ Sbjct: 139 VNQVLQVLTGVFITLVRDSMTVLALLIFLFYTNWRLTLVVAVILPVIGFLMSRINRRLRS 198 Query: 185 LNRDSLAVNAELTQLIEETTRAQQVIKIFGGHEYEKKRFHDRAENLRRYTMRMTAAFSST 244 LNR+ + E ++EE +V+K+ GG YE +RF+ LR Y MRM A Sbjct: 199 LNREHQNLTNEAAYVVEEAAGGYKVVKLHGGEAYESRRFNAMTNRLRGYAMRMAVAGGLN 258 Query: 245 VPITQLMTACAVAIVIVMALIQSGNGQITVGGFVSFITAMLMLLAPLKQLAEINGPLQRG 304 P+TQ + A A+++++ +A++Q+ Q TVGGF F+ AML+L++PLK L ++N P+QRG Sbjct: 259 QPVTQFLAALALSVILAIAMVQAQANQTTVGGFTGFVMAMLLLISPLKHLTDVNQPMQRG 318 Query: 305 MAAAEEVYKLIDKTPERVTGEALQQRAQGEVELVDVSFSYPGHEQQALKNINLRVRAGET 364 + AAE ++ LID E G RA+G++ V+F Y + AL +I+L V+AGE Sbjct: 319 LTAAEFIFGLIDTPIEPQDGGKHIDRARGDLRFEHVTFRYGPDGRAALDSIDLHVKAGEI 378 Query: 365 VAFVGMSGGGKSTLVSLLPGFHSVTAGKILLDGRDIESISLLSLRQQIAMVNQNTVLFDD 424 VA VG SG GK+TLV+LLP F T+G+I+LDG + +SL LR+QIA V+Q+ VLF+D Sbjct: 379 VALVGPSGSGKTTLVNLLPRFFEPTSGRIVLDGDALADLSLQDLRRQIAFVSQDVVLFND 438 Query: 425 TLAANISYGDQSP---DPARILAAVEAAHLTDVVQGLPQGMETRIGDNGSRLSGGQRQRV 481 T+AAN++YG + D AR+ A+EAA+LTDVV LP G++T IGDNGS+LSGGQRQR+ Sbjct: 439 TIAANVAYGARDASEIDMARVRRALEAAYLTDVVDNLPDGVDTNIGDNGSKLSGGQRQRL 498 Query: 482 AIARAIYKDAPILILDEATSALDTESERAVQAALERLMQGRTTFVIAHRLSTIERADRIV 541 AIARA+YKDAPILILDEATSALD+ESER VQAALE LMQGRTT VIAHRLSTIE ADRIV Sbjct: 499 AIARAVYKDAPILILDEATSALDSESERQVQAALEALMQGRTTLVIAHRLSTIENADRIV 558 Query: 542 VLVHGQIAEIGNHQELLQRDGVYANLYRLQFSQQ 575 VL HGQI E G H+ELL RDG+YA L+R+QF+ Q Sbjct: 559 VLEHGQIVEAGTHRELLDRDGLYAGLHRIQFATQ 592 >msbA [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Eco Escherichia coli K12 Length = 582 Score = 460 bits (1184), Expect = e-129, Method: Compositional matrix adjust. Identities = 231/571 (40%), Positives = 367/571 (64%), Gaps = 5/571 (0%) Query: 7 KRLAALHWPYKKRLALAFLGMIVTAATEPVVPYIFQVLLDKGFVGKPTFSL--WLVPAAV 64 +RL P+K L +A + +I+ AA++ + + + LLD GF GK S+ W+ P V Sbjct: 14 RRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGF-GKTDRSVLVWM-PLVV 71 Query: 65 IGIFLIRGMATFTSTYMMTWVSTRILNELRRQMFARMLDLPIHFYATNTVGKVINSMMFE 124 IG+ ++RG+ ++ S+Y ++WVS +++ +RR++F M+ +P+ F+ + G +++ + ++ Sbjct: 72 IGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYD 131 Query: 125 VQQIIDMVTKVFTSILRSALTVLGLLGWLLYLNWTLTIVTLVLLPLVSIVVRATGKRLKK 184 +Q+ + +++R +++GL + Y +W L+I+ +VL P+VSI +R KR + Sbjct: 132 SEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRN 191 Query: 185 LNRDSLAVNAELTQLIEETTRAQQVIKIFGGHEYEKKRFHDRAENLRRYTMRMTAAFSST 244 ++++ ++T E+ + + + IFGG E E KRF + +R M+M +A S + Sbjct: 192 ISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSIS 251 Query: 245 VPITQLMTACAVAIVIVMALIQSGNGQITVGGFVSFITAMLMLLAPLKQLAEINGPLQRG 304 PI QL+ + A+A V+ A S +T G ++M+ L+ PLK L +N QRG Sbjct: 252 DPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRG 311 Query: 305 MAAAEEVYKLIDKTPERVTGEALQQRAQGEVELVDVSFSYPGHEQQALKNINLRVRAGET 364 MAA + ++ ++D E+ G+ + +RA G+VE +V+F+YPG + AL+NINL++ AG+T Sbjct: 312 MAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKT 371 Query: 365 VAFVGMSGGGKSTLVSLLPGFHSVTAGKILLDGRDIESISLLSLRQQIAMVNQNTVLFDD 424 VA VG SG GKST+ SL+ F+ + G+IL+DG D+ +L SLR Q+A+V+QN LF+D Sbjct: 372 VALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFND 431 Query: 425 TLAANISYG-DQSPDPARILAAVEAAHLTDVVQGLPQGMETRIGDNGSRLSGGQRQRVAI 483 T+A NI+Y + +I A A+ D + + G++T IG+NG LSGGQRQR+AI Sbjct: 432 TVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAI 491 Query: 484 ARAIYKDAPILILDEATSALDTESERAVQAALERLMQGRTTFVIAHRLSTIERADRIVVL 543 ARA+ +D+PILILDEATSALDTESERA+QAAL+ L + RT+ VIAHRLSTIE+AD IVV+ Sbjct: 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVV 551 Query: 544 VHGQIAEIGNHQELLQRDGVYANLYRLQFSQ 574 G I E G H +LL+ GVYA L+++QF Q Sbjct: 552 EDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ 582 >ZmsbA [V] COG1132 ABC-type multidrug transport system, ATPase and permease components EcZ Escherichia coli O157:H7 EDL933 Length = 582 Score = 460 bits (1184), Expect = e-129, Method: Compositional matrix adjust. Identities = 231/571 (40%), Positives = 367/571 (64%), Gaps = 5/571 (0%) Query: 7 KRLAALHWPYKKRLALAFLGMIVTAATEPVVPYIFQVLLDKGFVGKPTFSL--WLVPAAV 64 +RL P+K L +A + +I+ AA++ + + + LLD GF GK S+ W+ P V Sbjct: 14 RRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGF-GKTDRSVLVWM-PLVV 71 Query: 65 IGIFLIRGMATFTSTYMMTWVSTRILNELRRQMFARMLDLPIHFYATNTVGKVINSMMFE 124 IG+ ++RG+ ++ S+Y ++WVS +++ +RR++F M+ +P+ F+ + G +++ + ++ Sbjct: 72 IGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYD 131 Query: 125 VQQIIDMVTKVFTSILRSALTVLGLLGWLLYLNWTLTIVTLVLLPLVSIVVRATGKRLKK 184 +Q+ + +++R +++GL + Y +W L+I+ +VL P+VSI +R KR + Sbjct: 132 SEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRN 191 Query: 185 LNRDSLAVNAELTQLIEETTRAQQVIKIFGGHEYEKKRFHDRAENLRRYTMRMTAAFSST 244 ++++ ++T E+ + + + IFGG E E KRF + +R M+M +A S + Sbjct: 192 ISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSIS 251 Query: 245 VPITQLMTACAVAIVIVMALIQSGNGQITVGGFVSFITAMLMLLAPLKQLAEINGPLQRG 304 PI QL+ + A+A V+ A S +T G ++M+ L+ PLK L +N QRG Sbjct: 252 DPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRG 311 Query: 305 MAAAEEVYKLIDKTPERVTGEALQQRAQGEVELVDVSFSYPGHEQQALKNINLRVRAGET 364 MAA + ++ ++D E+ G+ + +RA G+VE +V+F+YPG + AL+NINL++ AG+T Sbjct: 312 MAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKT 371 Query: 365 VAFVGMSGGGKSTLVSLLPGFHSVTAGKILLDGRDIESISLLSLRQQIAMVNQNTVLFDD 424 VA VG SG GKST+ SL+ F+ + G+IL+DG D+ +L SLR Q+A+V+QN LF+D Sbjct: 372 VALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFND 431 Query: 425 TLAANISYG-DQSPDPARILAAVEAAHLTDVVQGLPQGMETRIGDNGSRLSGGQRQRVAI 483 T+A NI+Y + +I A A+ D + + G++T IG+NG LSGGQRQR+AI Sbjct: 432 TVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAI 491 Query: 484 ARAIYKDAPILILDEATSALDTESERAVQAALERLMQGRTTFVIAHRLSTIERADRIVVL 543 ARA+ +D+PILILDEATSALDTESERA+QAAL+ L + RT+ VIAHRLSTIE+AD IVV+ Sbjct: 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVV 551 Query: 544 VHGQIAEIGNHQELLQRDGVYANLYRLQFSQ 574 G I E G H +LL+ GVYA L+++QF Q Sbjct: 552 EDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ 582 >ECs0997 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Ecs Escherichia coli O157:H7 Length = 582 Score = 460 bits (1184), Expect = e-129, Method: Compositional matrix adjust. Identities = 231/571 (40%), Positives = 367/571 (64%), Gaps = 5/571 (0%) Query: 7 KRLAALHWPYKKRLALAFLGMIVTAATEPVVPYIFQVLLDKGFVGKPTFSL--WLVPAAV 64 +RL P+K L +A + +I+ AA++ + + + LLD GF GK S+ W+ P V Sbjct: 14 RRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGF-GKTDRSVLVWM-PLVV 71 Query: 65 IGIFLIRGMATFTSTYMMTWVSTRILNELRRQMFARMLDLPIHFYATNTVGKVINSMMFE 124 IG+ ++RG+ ++ S+Y ++WVS +++ +RR++F M+ +P+ F+ + G +++ + ++ Sbjct: 72 IGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYD 131 Query: 125 VQQIIDMVTKVFTSILRSALTVLGLLGWLLYLNWTLTIVTLVLLPLVSIVVRATGKRLKK 184 +Q+ + +++R +++GL + Y +W L+I+ +VL P+VSI +R KR + Sbjct: 132 SEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRN 191 Query: 185 LNRDSLAVNAELTQLIEETTRAQQVIKIFGGHEYEKKRFHDRAENLRRYTMRMTAAFSST 244 ++++ ++T E+ + + + IFGG E E KRF + +R M+M +A S + Sbjct: 192 ISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSIS 251 Query: 245 VPITQLMTACAVAIVIVMALIQSGNGQITVGGFVSFITAMLMLLAPLKQLAEINGPLQRG 304 PI QL+ + A+A V+ A S +T G ++M+ L+ PLK L +N QRG Sbjct: 252 DPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRG 311 Query: 305 MAAAEEVYKLIDKTPERVTGEALQQRAQGEVELVDVSFSYPGHEQQALKNINLRVRAGET 364 MAA + ++ ++D E+ G+ + +RA G+VE +V+F+YPG + AL+NINL++ AG+T Sbjct: 312 MAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKT 371 Query: 365 VAFVGMSGGGKSTLVSLLPGFHSVTAGKILLDGRDIESISLLSLRQQIAMVNQNTVLFDD 424 VA VG SG GKST+ SL+ F+ + G+IL+DG D+ +L SLR Q+A+V+QN LF+D Sbjct: 372 VALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFND 431 Query: 425 TLAANISYG-DQSPDPARILAAVEAAHLTDVVQGLPQGMETRIGDNGSRLSGGQRQRVAI 483 T+A NI+Y + +I A A+ D + + G++T IG+NG LSGGQRQR+AI Sbjct: 432 TVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAI 491 Query: 484 ARAIYKDAPILILDEATSALDTESERAVQAALERLMQGRTTFVIAHRLSTIERADRIVVL 543 ARA+ +D+PILILDEATSALDTESERA+QAAL+ L + RT+ VIAHRLSTIE+AD IVV+ Sbjct: 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVV 551 Query: 544 VHGQIAEIGNHQELLQRDGVYANLYRLQFSQ 574 G I E G H +LL+ GVYA L+++QF Q Sbjct: 552 EDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ 582 >STM0984 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Sty Salmonella typhimurium LT2 Length = 582 Score = 459 bits (1182), Expect = e-129, Method: Compositional matrix adjust. Identities = 233/571 (40%), Positives = 365/571 (63%), Gaps = 5/571 (0%) Query: 7 KRLAALHWPYKKRLALAFLGMIVTAATEPVVPYIFQVLLDKGFVGKPTFS--LWLVPAAV 64 +RL P+K L +A + +I+ AA++ + + + LLD GF GK S LW+ P V Sbjct: 14 RRLWPTIAPFKAGLIVAGIALILNAASDTFMLSLLKPLLDDGF-GKTDRSVLLWM-PLVV 71 Query: 65 IGIFLIRGMATFTSTYMMTWVSTRILNELRRQMFARMLDLPIHFYATNTVGKVINSMMFE 124 IG+ ++RG+ ++ S+Y ++WVS +++ +RR++F M+ +P+ F+ + G +++ + ++ Sbjct: 72 IGLMILRGITSYISSYCISWVSGKVVMTMRRRLFGHMMGMPVAFFDKQSTGTLLSRITYD 131 Query: 125 VQQIIDMVTKVFTSILRSALTVLGLLGWLLYLNWTLTIVTLVLLPLVSIVVRATGKRLKK 184 +Q+ + +++R +++GL + Y +W L+I+ +VL P+VSI +R KR + Sbjct: 132 SEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILVVLAPIVSIAIRVVSKRFRS 191 Query: 185 LNRDSLAVNAELTQLIEETTRAQQVIKIFGGHEYEKKRFHDRAENLRRYTMRMTAAFSST 244 ++++ ++T E+ + + + IFGG E E KRF + +R M+M +A S + Sbjct: 192 ISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNKMRLQGMKMVSASSIS 251 Query: 245 VPITQLMTACAVAIVIVMALIQSGNGQITVGGFVSFITAMLMLLAPLKQLAEINGPLQRG 304 PI QL+ + A+A V+ A S +T G ++M+ L+ PLK L +N QRG Sbjct: 252 DPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRG 311 Query: 305 MAAAEEVYKLIDKTPERVTGEALQQRAQGEVELVDVSFSYPGHEQQALKNINLRVRAGET 364 MAA + ++ ++D E+ G+ + RA G++E +V+F+YPG E AL+NINL++ AG+T Sbjct: 312 MAACQTLFAILDSEQEKDEGKRVIDRATGDLEFRNVTFTYPGREVPALRNINLKIPAGKT 371 Query: 365 VAFVGMSGGGKSTLVSLLPGFHSVTAGKILLDGRDIESISLLSLRQQIAMVNQNTVLFDD 424 VA VG SG GKST+ SL+ F+ + G IL+DG D+ +L SLR Q+A+V+QN LF+D Sbjct: 372 VALVGRSGSGKSTIASLITRFYDIDEGHILMDGHDLREYTLASLRNQVALVSQNVHLFND 431 Query: 425 TLAANISYG-DQSPDPARILAAVEAAHLTDVVQGLPQGMETRIGDNGSRLSGGQRQRVAI 483 T+A NI+Y + +I A A+ D + + G++T IG+NG LSGGQRQR+AI Sbjct: 432 TVANNIAYARTEEYSREQIEEAARMAYAMDFINKMDNGLDTIIGENGVLLSGGQRQRIAI 491 Query: 484 ARAIYKDAPILILDEATSALDTESERAVQAALERLMQGRTTFVIAHRLSTIERADRIVVL 543 ARA+ +D+PILILDEATSALDTESERA+QAAL+ L + RT+ VIAHRLSTIE+AD IVV+ Sbjct: 492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEQADEIVVV 551 Query: 544 VHGQIAEIGNHQELLQRDGVYANLYRLQFSQ 574 G I E G H ELL + GVYA L+++QF Q Sbjct: 552 EDGIIVERGTHSELLAQHGVYAQLHKMQFGQ 582